A retrospective study found that 62% of veterans reported getting sunburned while deployed, and 29% noticed changes in their moles, highlighting a potential deficiency in sun protection among military personnel. The study suggests room for improvement in skin cancer prevention and early detection in the military population.
A new study found that children and teens with ADHD lag behind others in forming connections within their brains, particularly between networks controlling internal and external tasks. This lag may contribute to the disorder's hallmark symptoms of distraction and difficulty focusing.
Researchers found that patients taking generic statins were more likely to adhere to their medication and had a significantly lower rate of cardiovascular events and death. Generic statins were also associated with improved clinical outcomes due to lower out-of-pocket costs.
A study published by the American College of Cardiology found that higher cardiorespiratory fitness levels can delay the natural increase of systolic and diastolic blood pressure with age. Men with high fitness levels experience a later onset of prehypertension, with systolic blood pressure increasing around age 54 and diastolic blood ...
Researchers at Montana State University provided the first blueprint of a bacterium's molecular machinery, showing how bacterial immune systems fight off viruses. By understanding CRISPR mechanisms, scientists can potentially develop therapies for plant, animal, and human diseases.
A team of University of Pittsburgh professors is working on a project to transition the US power grid to direct current (DC) using a $800,000 grant from the Henry L. Hillman Foundation. DC technology has the potential to improve energy efficiency and promote renewable energy, especially in low-income areas. The researchers aim to devel...
A randomized trial found that radiation therapy (RT) alone is as effective in reducing dysphagia as chemoradiotherapy (CRT), allowing patients to forgo chemotherapy. The study also demonstrated comparable survival prognosis between the two groups, highlighting a potential simpler treatment option.
The US CoreValve High Risk Trial found that transcatheter aortic valve replacement (TAVR) provided lower 12-month mortality compared to surgical aortic valve replacement (SAVR) in high-risk patients. TAVR also showed significant improvements in quality of life, with estimated gains of 0.24 life years and 0.20 quality-adjusted life years.
A comprehensive look at lithium ion battery electrodes reveals that rapid-charging and high-power discharging may not damage the electrode as much as previously thought. The research suggests modifying electrodes or changing charging processes could promote uniform charging and discharging, extending battery life.
A recent study suggests that treating mildly elevated blood pressure in low-risk individuals may not be effective in reducing cardiovascular disease or death. Experts urge clinicians to re-examine the threshold for treatment and promote lifestyle changes, such as weight loss and increased exercise, instead of relying on medication.
A new study reveals climate change's complex effects on land and water, contradicting the 'DDWW' principle. While some regions become drier or wetter, others experience no trends, highlighting the need for a more nuanced understanding of climate change.
The CoreValve US Pivotal trial showed improved survival benefit in patients with aortic stenosis, with low rates of all-cause mortality and major stroke after two years. The study demonstrated durable improvement in hemodynamic valve performance and low rates of moderate or severe aortic insufficiency.
A new radiotherapy strategy for treating advanced small-cell lung cancer significantly prolongs long-term survival and reduces cancer recurrence in the chest. The study found that patients treated with thoracic radiation therapy had a 50% lower risk of cancer recurrence compared to those who did not receive it.
A shorter course of androgen deprivation therapy (ADT) has been found to improve the quality of life for high-risk prostate cancer patients, with faster recovery times and better outcomes compared to a longer 36-month ADT regimen. The study analyzed data from 561 patients who received radiation therapy and long-term ADT.
The PARTNER I trial found that TAVR demonstrated persistent mortality benefits and improved functional status after five years compared to standard therapy. This is the first long-term analysis of the randomized PARTNER I trial, which initially showed TAVR as an accepted therapy for inoperable patients with severe aortic stenosis.
A recent study by University of California, Berkeley researchers has found evidence of neural compensation in individuals with beta-amyloid deposits, a hallmark of Alzheimer's disease. This discovery could help explain how some older adults maintain normal cognitive function despite the presence of these deposits.
Marie Claude Morice, a world-renowned interventional cardiologist, has been recognized with the Master Clinical Operator Award at TCT for her technical expertise and innovative contributions to the field of interventional cardiology. Her extensive research and clinical experience have led to significant advancements in the treatment of...
Research reveals Asian monsoon's origins date back 40 million years to high CO2 levels and warmer temperatures. The climate pattern was stronger then than now and weakened with decreasing CO2 levels during an ice age.
Researchers have developed a new method to measure structurally modified proteins in complex biological samples, enabling the analysis of thousands of proteins. The method uses a combination of digestion enzymes and Selected Reaction Monitoring to quantify protein quantities and determine structural changes.
The biospleen device uses magnetic beads coated with genetically engineered MBL proteins to remove pathogens and toxins from the blood. In laboratory tests, it filtered out over 90% of key sepsis pathogens within five hours.
A randomized phase II trial found that Manuka honey was not effective in reducing esophagitis pain during radiation therapy for lung cancer patients. The study enrolled 163 patients who received either standard supportive care or Manuka honey supplements, but showed no significant differences in pain levels.
The CLEAN-TAVI trial found that using a cerebral protection device during TAVR significantly reduced the number and volume of cerebral lesions in high-risk patients with severe aortic stenosis. The study showed improved outcomes at two and seven days post-procedure.
Researchers at VIB/VUB have created a detailed three-dimensional image of the pores through which curli building blocks cross the bacterial cell wall, shedding light on biofilm formation. This breakthrough could lead to the development of small molecules that inhibit unwanted biofilm growth and pave the way for new applications in fiel...
A major international study identified 23 new genetic variants associated with increased risk of prostate cancer, explaining a third of the inherited risk. Testing for these variants can identify 1% of men with a risk almost six times as high as the population average.
A study by the Stowers Institute for Medical Research reveals that the sea lamprey, a jawless vertebrate, exhibits a pattern of gene expression reminiscent of its jawed cousins, indicating that the genetic program used by jawed vertebrates was up and running ages before they possessed recognizable faces. This finding suggests that regu...
Research by the University of East Anglia found that walking and cycling to work improves mental health and wellbeing. Commuters who switched from driving to active transport reported improved concentration, reduced stress, and better psychological wellbeing.
University of Leeds researchers found that a single missed care step can lead to a 46% increased chance of death within a month of discharge and a 74% increased chance of dying within one year. The nine identified pathways of care include pre-hospital electrocardiogram, aspirin prescription, and cardiac rehabilitation referral.
Researchers developed a novel approach to target the activation of Ral proteins, which drive tumor growth in several human cancers. A compound called BQU57 proved most successful in slowing cancer cell growth and activation.
The ISAR-CLOSURE trial reported that vascular closure devices (VCD) are non-inferior to manual compression in patients undergoing transfemoral coronary angiography. VCDs were found to reduce time-to-hemostasis, but had a higher rate of repeat manual compressions.
The study found a sharp increase in early-stage breast cancer cases among 70-75 year olds after national screening was introduced, suggesting overdiagnosis. The researchers argue that personalized screening decisions based on remaining life expectancy and individual risk factors are necessary to avoid unnecessary overtreatment.
Researchers discovered that mice missing TRPML1 calcium channel developed similar muscle defects as those present in muscular dystrophy patients. Increasing the activity of this channel improved muscle membrane repair and restored function. The goal is to develop a drug that can activate TRPML1 for potential treatment in humans.
Researchers found that African Americans and Caribbean blacks who experience discrimination are at higher risk for anxiety, depression, and substance abuse. The type and frequency of discrimination matter, with hostile and character-based discrimination placing adults at considerable risk for mental health problems.
Researchers at UNC School of Medicine discovered how Period and Cryptochrome genes interact to control the circadian clock. The findings have implications for developing drugs for diseases such as cancer, diabetes, and metabolic syndrome.
A global study of over 87,000 individuals from diverse ethnic backgrounds has discovered 23 new genetic factors that contribute to the development of prostate cancer. The research, led by Keck School of Medicine at USC, provides valuable insights into the causes of this disease and may lead to better prevention strategies.
A study of over 41,000 patients with stage I and II Hodgkin's Disease found that those receiving consolidated radiation therapy had a higher 10-year survival rate of 84 percent compared to 76 percent for non-RT recipients. The data also showed a decrease in RT utilization, highlighting ongoing disparities in treatment.
Researchers found that high levels of VEGF-A and TGF-β1 before treatment correlated with lower survival rates and less complete tumor regression. A blood test for these proteins could help predict patients' pathological response and disease-free survival rates, allowing for more personalized treatment plans.
Researchers at NIST and the University of Waterloo directly entangled three photons, a breakthrough in quantum information systems. The use of superfast single-photon detectors enabled stable and high-quality results, paving the way for applications in quantum computing and quantum communications.
Research presented at ASTRO's 56th Annual Meeting found no association between radiation therapy and increased risk of lymphedema in women with clinically node-negative breast cancer. The study results provide reassurance for breast cancer patients regarding the impact of radiation therapy on lymphedema risk.
Dr. Mack, the first surgeon to receive the award, has made significant contributions to research involving minimally invasive surgery and percutaneous heart valve therapy. He has performed over 7,000 cardiac surgeries, including 3,000 heart valve procedures.
Researchers developed a methodology for describing dynamic sugar chain behaviors at atomic resolution, enabling the characterization of minor but biologically relevant conformational species. This breakthrough opens doors to observing flexible biomolecules as potential drug targets.
A new electroencephalography (EEG) tool has been developed to detect refractory idiopathic epilepsy in children, a condition that cannot be managed by antiepileptic drugs. The tool uses EEG classification analysis and identifies significant EEG features that distinguish refractory epilepsy from well-controlled forms.
Researchers at Wake Forest Baptist Medical Center developed a new method to coat blood vessels in lab-grown kidneys, allowing them to remain open for four hours. The breakthrough could potentially be applied to other complex organs, such as the liver and pancreas.
A new study by University of Vermont scientists predicts increased precipitation and temperature in the Lake Champlain region, leading to more extreme weather events and potential flooding. The forecast suggests a rise in average temperatures by mid-century, with some ski resorts experiencing a 50% decline in annual snowfall.
Tropical Storm Kalmaegi intensified as NASA's Aqua satellite captured its visible image approaching the Philippines. The storm is expected to strengthen over the next couple of days and potentially become a typhoon by September 13.
The proposed platform would leverage the cloud to expand individual device capabilities, supporting applications like healthcare, safety, and social interaction. The technology could also enable real-time searches of cell phone photos taken by people in the area to locate lost children.
The TRMM satellite detected powerful thunderstorms near Odile's center, dropping rain at a rate of over 196 mm/h. The combined data from TRMM and Aqua satellites showed the coldest cloud tops in storms circling Odile's center, with temperatures as low as -63F/-53C.
A large-scale study found that more than 70% of individuals with multiple sclerosis screened positive for one or more sleep disorders, highlighting the importance of diagnosing and managing these conditions. The study's findings suggest that sleep problems may be a hidden epidemic in the MS population, separate from MS fatigue.
The Selway complex of fires has grown to 1,659 fires, mostly contained. The Johnson Bar fire, sparked by a lightning strike, has affected 8,867 acres and is currently 55% contained. Warmer weather may increase fire activity.
A group of researchers recommend applying evolutionary biology to combat modern threats, proposing gene therapies, drought-resistant crop varieties, and conservation strategies to protect land with high genetic diversity. This approach can help develop more robust solutions to societal problems and promote sustainable development.
The current Ebola outbreak in West Africa requires a rapid global response to contain the virus, which has already killed nearly 2000 people and may infect up to 20,000. Experts warn that fear, mistrust, and lack of resources are exacerbating the situation.
The project aims to digitize images and data on aquatic and wetland plants, mollusks, and fish from the Great Lakes basin, targeting 2,550 species. The goal is to document species invasions and eventually prevent them.
Rates of high-dose opioid dispensing increased across provinces, with Ontario having the highest rates and Quebec the lowest. Provincial differences may be attributed to varying coverage, training, and marketing strategies.
The article proposes a connection between SLq(2) and the standard model, where preons are creation operators for fundamental particles. This extension describes a finer level of structure than the standard model, with open problems including gravitational binding and renormalization.
The NIH has awarded over $64 million to six institutions to create a database of human cellular responses, known as the Library of Integrated Network-based Cellular Signatures (LINCS). This will improve scientists' understanding of cell pathways and aid in the development of new therapies for many diseases.
Researchers found that removing only the rib cartilage, but leaving its surrounding perichondrium intact, allowed for rapid repair within one to two months. This discovery suggests the presence of progenitor or stem cells in the perichondrium, which could lead to new regenerative therapies.
A team from the University of Pennsylvania School of Medicine found that some behavioral defects in NF1 fish are not related to abnormal Ras, but can be corrected by drugs targeting another signaling pathway controlled by cAMP. Learning and memory defects can be treated with drugs modulating the Ras pathway.
Researchers at the University of Vienna successfully manipulated individual silicon atoms in graphene, revealing a previously unknown phenomenon where the silicon-carbon bond is inverted. This discovery opens promising possibilities for atomic-scale engineering and could lead to the creation of unique quantum structures.
Researchers found that endothelial cells in eyes with glaucoma are stiffer than healthy cells, leading to increased flow resistance and elevated pressure. This mechanical dysfunction may lead to a cure for the debilitating disease.
The Suomi NPP satellite captured high-resolution infrared images of Tropical Storm Edouard, revealing very high thunderstorms and cold cloud top temperatures. The storm is moving west-northwest at 16 mph, with forecasters predicting it may become a hurricane by September 15.
Researchers have discovered a new family of hexagonal rare earth ferrites that exhibit ferroelectricity and ferromagnetism simultaneously. This phenomenon enables the magnetoelectric memory effect, which could significantly improve energy efficiency in information storage and processing.