Scientists have unraveled a molecular mechanism of mRNA recognition, essential for understanding differential gene regulation in male and female organisms. This principle represents an essential and widespread mechanism of gene regulation in higher organisms.
A study by Physicians for a National Health Program finds that US hospital bureaucracy consumes a quarter of hospital budgets, driving inefficiency and diverting resources away from patient care. Single-payer reform could potentially save $150 billion annually on hospital overhead.
Scientists create doped graphene nanoribbons with nitrogen atoms, enabling directional electronic current flow and solving scaling issues. The development allows for the transfer of ultra-narrow graphene ribbons onto non-conductive materials, paving the way for future graphene-based electronics.
Researchers identified a gene called AMPK that can slow the aging process throughout the entire body when activated remotely in key organ systems. Activating AMPK in fruit flies increased their lifespans by about 30 percent and kept them healthier longer.
Researchers suggest that dark matter particles scattering with photons and neutrinos could explain the lack of small galaxies around the Milky Way. By tuning this interaction, scientists can learn more about dark matter's physics and its effects on galaxy formation.
E-cigarette nicotine refill cartridges contain high levels of nicotine, posing a risk to young children who may accidentally ingest them. The US CDC reports a massive rise in accidental poison calls related to e-cigarette refills, with over half involving children under 5.
A study found that tear gas exposure can lead to respiratory symptoms such as coughing, chest pain, and phlegm production in protesters, with the effects lasting up to two weeks. Researchers also discovered that people living near protest areas were exposed to harmful lung health effects from tear gas use.
The Miriam Hospital is part of a research collaboration that has received a $20 million grant from the National Institutes of Health (NIH) to develop an intravaginal ring (IVR) that can deliver powerful antiretroviral drugs to prevent the spread of sexually transmitted HIV in women. The project will test multiple-drug combinations to d...
Researchers confirm that textbook theory behind volcanoes is incorrect, with no evidence for narrow mantle plumes. Instead, large, slow-moving chunks of mantle drive volcano formation through plate tectonics.
Researchers found that the protein RBM4, crucial to gene splicing, is drastically decreased in multiple forms of human cancer, including lung and breast cancers. This discovery offers a new route toward therapies targeting altered genetic pathways that allow cancer cells to proliferate and spread.
Scientists have successfully demonstrated how combining hexagonal boron nitride and graphene can create perfect crystals capable of being used in ultra-high frequency devices. The research paves the way for innovative applications in high-frequency electronics.
A study found that autistic males have lower levels of estrogen receptors and aromatase, an enzyme converting testosterone to estradiol. This could lead to increased testosterone levels, potentially contributing to the disorder's prevalence in men. The findings suggest a possible reason for the gender bias in autism diagnosis.
Pitt researchers identify natural TH17 cells as a key player in preventing oral thrush, a common infection among HIV patients and those with impaired immune systems. These innate immune cells produce IL-17 to fight Candida albicans, a fungus that causes painful white lesions.
Researchers at University of Wisconsin-Madison found that the stiffness of surfaces on which stem cells are grown influences cell fate. A soft, brain tissue-like surface directed cells to become neurons, while stiffer surfaces favored the stem cell state.
Scientists have identified a new species of titanosaurian dinosaur, Rukwatitan bisepultus, in Tanzania, with unique features that set it apart from other finds. The discovery contributes to understanding the evolution of species in sub-Saharan Africa and the global portrait of titanosaurians.
Post-tropical cyclone Norbert is weakening and losing strength, but still causing rough surf along the Baja California coast. The storm's remnants are expected to spread heavy rains and life-threatening flash flooding across northern Mexico and the southwestern United States.
A new study suggests that addressing psychological needs can help alleviate severe asthma symptoms. The research found a 42% reduction in hospital days among patients who received psychological support after experiencing an asthma exacerbation.
Researchers at MIT have developed a solar-powered desalination system that can provide clean drinking water to villages in India. The system, which uses electrodialysis technology, is more energy-efficient and cost-effective than traditional reverse-osmosis systems.
BioEYES K-12 program delivers two-week environmental curriculum using live zebrafish to teach students about local watersheds and pollution. The award supports the delivery of 'Your Watershed, Your Backyard' curriculum to 90 middle school students from Baltimore City Public Schools.
A new study shows that total facial rejuvenation combining extensive facelifts, midface implants, and laser resurfacing can be performed safely at one time. Patients experienced normal wound healing and no reported complications after the procedure.
Using a neutron beam, researchers at Ohio State University track lithium atoms in real time as batteries charge and discharge. This technique, called neutron depth profiling, may help explain why rechargeable batteries lose capacity over time.
A new study found that vulnerable populations in Toronto reported more discrimination by healthcare workers based on their housing status, mental health, or substance abuse issues than race. Forty-two percent of people surveyed experienced at least one form of perceived discrimination.
A new University of Michigan study found significant variation in hospital admissions for ER patients with common non-life-threatening conditions, resulting in estimated annual costs of $5 billion and $266 billion. The study analyzed data from 961 hospitals and 28.5 million emergency visits, revealing that some conditions had high rate...
A team of researchers at Monash University has developed a light detector based on graphene that can detect light over an unusually broad range of wavelengths, including terahertz waves. This breakthrough could lead to inexpensive infrared cameras or night-vision goggles with unparalleled sensitivity and speed.
A new study predicts that climate change will increase forest fire danger in Europe by 200% by 2090. However, prescribed burns and improved firefighting can reduce this risk to below 50%. The study examined adaptation options for forest fires on a pan-European scale.
Researchers have developed new genomic editing tools to create genetically identical patient-derived iPSCs for disease modeling. These advancements will improve the accuracy of drug testing and cell-based therapies, revolutionizing human disease modeling and treatment.
Researchers discovered two potential therapeutic targets to treat pulmonary arterial hypertension, a deadly disease marked by high blood pressure in the lungs. The targets involve suppressing abnormal proliferation of smooth muscle cells and signaling molecules involved in the disease.
According to a Northwestern Medicine study, only one in four students with asthma and half of children with food allergies have emergency health management plans in place at school. This underutilization leaves schools inadequately prepared to handle medical emergencies and puts the most vulnerable students at risk.
Scientists from the John Innes Centre are developing a new business concept to revive heritage lines of barley for brewing, offering greater choice and added value to farmers and brewers. The venture aims to provide sustainable production and high-quality malting barley, capitalizing on the demand for unique beer ingredients.
A new study by UNC researchers led by Kathleen Caron, Ph.D., shows that deleting CXCR7 allows adrenomedullin to run rampant, triggering enlarged heart and overgrowth of lymphatic vessels. The study highlights the importance of understanding the role of CXCR7 in cardiovascular health.
Scientists identified a compound that effectively inhibits an enzyme crucial to Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS) viruses. The compound has a different mode of action for each virus due to slight differences in the enzyme.
A study of over 13,000 men found that non-allergic asthma was significantly more common in children whose fathers smoked before conception. The risk of asthma increased with the duration and age of paternal smoking.
Scientists analyzed depictions of animals in ancient Egyptian artifacts to reconstruct the large mammal community that lived in the Nile Valley. The study found that species extinctions led to a decline in ecosystem stability, with only eight species remaining today compared to 37 six millennia ago.
Researchers discovered that patients with lung cancer have a higher breath temperature than those without. The study also identified a cut-off value in temperature measurement to accurately diagnose lung cancer.
Researchers developed an antibody-based drug, mepolizumab, to replace steroid-based treatments for patients with severe eosinophilic asthma. The new treatment has improved outcomes and reduced side effects in these patients, offering a more personalized approach to asthma care.
Researchers have identified 871 wild plant species in China with potential to adapt globally important crops, including rice and wheat. These crop wild relatives (CWR) can improve crop tolerance and nutritional qualities.
A UT Arlington study found that teens living with two college-educated parents are significantly less likely to drink alcohol or smoke marijuana. The presence of both parents is a strong protective factor for African-American adolescents, with white teenagers being 69% more likely to engage in substance abuse than black peers.
Researchers have adapted a biomedical technique to study ocean organisms, identifying and measuring proteins to understand biochemical reactions. The study reveals how microbes respond to environmental cues and ecosystem changes over large regions.
A Baylor University study finds that young people who regularly attend religious services are less likely to experiment with drugs and alcohol. Feeling connected to a 'higher power' may help overcome peer pressure and lead to increased prosocial behaviors and reduced narcissistic behavior.
Grand Challenges Canada awards $2.4 million to 22 projects addressing major health burdens in low-resource countries, including tuberculosis, deafness, and mental health problems. Innovations include a personal eyepiece for deaf children and sterile drill covers for low-cost orthopaedic trauma surgery.
The International Balzan Foundation announced the 2014 prize winners, including Mario Torelli, Ian Hacking, G. David Tilman, Dennis Sullivan, and Vivre en famille. The foundation's awards focus on innovative research in various fields, with half of the prize money dedicated to supporting young scholars.
An Australian study found that belly dancers have a more positive body image than college students, focusing on the experience rather than appearance. This embodying activity allows women to feel good about themselves and explore their sensual selves in a safe and creative way.
Researchers at Cornell University developed a shape-changing soft robot that can navigate through snow, puddles of water, flames, and withstand crushing forces. The robot's resilience has implications for search and rescue missions.
A new study found that taking short walking breaks during prolonged sitting can significantly improve endothelial function and reduce cardiovascular risks. The research involved 11 healthy men who sat for three hours with or without regular breaks, showing that breaks can prevent decline in arterial function.
A new paper published in Nature Communications suggests that simple traits like butterfly wing patterns may have a shared genetic source. Researchers identified a single gene, WntA, responsible for the evolution of similar color patterns in two distantly related butterfly species.
Scientists at the University of Birmingham have identified 'hotspots' around the globe where crop wild relatives can be conserved to secure future global food resources. The highest concentration of these species is found in the Middle East's Fertile Crescent, threatening their survival due to climate change and conflict.
Researchers at the University of Copenhagen have developed a new screening method that reduces precious sample consumption by a billion times, enabling faster and cheaper drug development. The method uses nanotechnology to study cell membrane proteins binding drugs like cannabis and adrenaline.
A team led by Lin Zhang identified a non-protein-coding RNA, FAL1, whose expression is linked to ovarian cancer. The study found that blocking the activity of FAL1 reduces cancer cells' growth and may serve as a biomarker for BRCA-related cancer prognosis.
Researchers successfully harness a mouse's immune system to remove toxic proteins in the brain associated with Alzheimer's disease. The treatment approach, which stimulates the natural immune system, showed promise in reducing amyloid beta plaques and tau tangles.
A new computer model simulates how plants grow under varying conditions, providing valuable insights into nutrient distribution and adaptation to changing climates. The study's findings could lead to the development of crop varieties with high yields in specific environmental conditions.
A Yale study finds that the conversion of forests to cropland worldwide has reduced global BVOC emissions, leading to a net cooling effect on climate temperatures. The loss of dark-colored forests and reduction in emissions of short-lived climate pollutants have offset warming caused by increased fossil fuel carbon dioxide emissions.
A nationwide study found significant declines in central line-associated bloodstream infections and ventilator-associated pneumonias among critically ill neonates and children. The rates of these infections decreased by 61% in NICUs and 76% in PICUs, resulting in estimated cost savings of $131 million.
A commentary calls for physicians to carefully review older patients' medication lists and consider their anticipated life expectancy, goals of care, and treatment targets. This approach can help reduce the number of unnecessary prescriptions and minimize harm from medications in older adults.
Researchers discovered that a unique twist in the nectar spur of a bird-pollinated flower allows for more efficient pollen placement on sunbirds' heads and bills. This adaptation increases the likelihood of successful pollination and reduces competition among plant species.
A multicenter trial of 1358 children found intermittent montelukast reduced wheezing episodes only in those with the specific genetic subtype. The treatment was ineffective in children without this genotype, highlighting the need for targeted research.
Researchers discovered that a single-celled organism, Oxytricha trifallax, can break its DNA into nearly quarter-million pieces and reassemble them in 60 hours for mating. This ability highlights the complexity of life on Earth, with intricate mechanisms to reconstruct chromosomes.
Researchers found that viruses can contaminate surfaces within 2-4 hours, spreading to 40-60% of workers and visitors. Disinfecting wipes with quaternary ammonium compounds (QUATS) reduced virus spread by 80-99% when used in conjunction with hand hygiene.
A study published in JAMA Neurology found that immunosuppressant MMF treatment significantly reduced relapse rates and improved disability scores in patients with neuromyelitis optica spectrum disorder (NMOSD). The results suggest MMF may be an effective treatment option for preventing attacks and resulting disabilities in these patients.
The Cloud-Aerosol Transport System (CATS) will provide critical measurements on the International Space Station, demonstrating new technology and proving inexpensive missions can make accurate climate predictions. The instrument will track aerosols over population centers and reveal shifts in global climate.
The Illinois Medicaid primary care case management program, implemented in 2006, was associated with substantial savings, reductions in inpatient and emergency care, and improvements in quality measures. The programs promoted preventive care, reduced redundancy of services, and improved chronic disease management.