A panel of experts has called for improved screening and treatment of psoriatic arthritis (PsA) to help millions worldwide. The condition causes painful joint inflammation and can lead to irreversible joint damage if left untreated.
Researchers have discovered an innovative way to visualize where proteins touch each other using brightly hued dyes, a breakthrough that could lead to new treatments for various diseases. The technique involves mixing dyes with proteins and then separating them to reveal the 'hot spots' where proteins interlock.
A new study by UNC researchers provides evidence that could help improve CF pharmacotherapies. They found that a mutant CFTR protein loses its ability to function properly when in the presence of two drugs, suggesting that drug developers should take this destabilization effect into account.
A combination treatment of gene inhibitor AAVshPTEN and salmon fibrin injections restored voluntary motor function impaired by spinal cord injury in rodents. This breakthrough expands on previous research at UCI and provides a novel scaffold for neuronal axons to grow and link up again.
A recent study by Johns Hopkins Bloomberg School of Public Health found that older Americans with multiple chronic medical conditions have shorter life expectancies. On average, a 75-year-old woman with five chronic conditions will only live to the age of 87.
Physicists Sergei Filippov and Mario Ziman have found a way to preserve quantum entanglement in particles passing through an amplifier and when transmitting signals over long distances. This breakthrough allows for more efficient quantum computing and secure communication channels.
Research found that sleep-deprived individuals who viewed photos of a crime and then read false information were more likely to report remembering the false details. The study suggests that chronic sleep deprivation may increase susceptibility to false memories, with implications for eyewitness reliability.
A systematic review of 10 studies confirms ketamine's safety in critically ill patients, providing analgesia, sedation, and amnesia without significant increases in intracranial pressure or neurological outcomes. The findings support the use of ketamine as a routine treatment for life-threatening infections and unconscious patients.
A new electronic chip with nano-sized chemical sensors can detect miniscule concentrations of hazardous materials in the air, surpassing even the most advanced detection dogs. The breakthrough technology has been tested on various explosives and shows great promise for providing a safer world.
Researchers focus on areas of memory and learning to treat obesity, suggesting a link between the two diseases. The 'vicious cycle' model proposes that overeating leads to brain pathologies, which can weaken control over thoughts and behaviors.
The Duke Lemur Center has made nearly 50 years of life history data for endangered primates available online. The database contains detailed records of over 3600 animals representing 27 species, including birth and death dates, breeding habits, and health information.
A 3D image of a Paleolithic child's skull shows compound fractures indicating blunt force trauma, likely caused by interpersonal violence. The child is believed to have suffered from severe traumatic brain injury, which may have impacted their social communication and behavior.
A new study from UC San Diego suggests dogs may have a more basic form of jealousy that evolved to protect social bonds from interlopers. Dogs exhibited aggressive behaviors like snapping and pushing when owner showed affection to a stuffed dog, indicating they were motivated to break up the connection.
Researchers tested dogs' reactions to owners' affection for realistic and non-realistic objects, finding stronger jealous behaviors towards the dog-like object. This study suggests jealousy may have a primordial form in animals, including humans.
A study by University of Cincinnati researchers found that combination antiretroviral therapy can reduce HCV viral loads and liver injury in HIV patients co-infected with HCV. This approach supports the concept of early and uninterrupted HIV therapy to prevent liver disease in individuals with HCV/HIV infection.
A researcher from Moscow Institute of Physics and Technology has developed a reliable mathematical model of Titan's atmosphere, which matches the latest data surprisingly well. The model takes into account various chemical reactions between neutral molecules and ions in the upper layers of Titan's atmosphere.
Researchers have linked autistic behaviors in Fragile X syndrome to the MMP-9 enzyme, which can be targeted therapeutically. The study found that deleting MMP-9 favorably impacts behaviors associated with FXS, offering new hope for treating the disorder.
A new study found that obese workers have significantly shorter endurance times when performing workplace tasks compared to their non-obese counterparts. The study also revealed greater declines in task performance among females with obesity, highlighting the need for longer rest breaks and ergonomic redesigns.
Researchers propose a new strategy for preventing age-related diseases, focusing on treating metabolic and molecular causes. They suggest lifestyle interventions such as personalized diets and exercise programs to delay chronic disease onset.
A study of over 180,000 women found that imprinted genes, active only when inherited from one parent, influence the age of puberty in girls. These genetic variations were associated with a difference in development between boys and girls.
A study published in Psychological Science found that individuals with high subjective knowledge are more prone to choice overload and are less likely to purchase products with numerous options. In contrast, those with low subjective knowledge tend to prefer a wide range of choices when the information is easily understandable.
A team of researchers has discovered a previously unknown mechanism for wear in metals, which could lead to improved durability of metal parts. The findings show that tiny bumps and surface defects can form through a swirling, fluid-like behavior in solid metals, leading to cracks and wear particles.
A team of researchers from UCLA discovered that autophagy, a process that clears damaged proteins, is impaired in people with Type 2 diabetes, leading to the destruction of insulin-producing beta cells. This impairment contributes to the accumulation of toxic IAPP protein.
Research in Saanich Inlet reveals sulfur-oxidizing bacterial group SUP05 dominates oxygen-starved regions, driving carbon dioxide fixation and nutrient cycling. The study sheds light on the ecological impact of microbial respiration in the oxygen-poor ocean.
Researchers found that bioidentical hormone treatments reduced tumor recurrence and improved cardiovascular and bone health, while also increasing physical activity and cognition. The study's results are promising but require further validation, providing a new direction in the search for alternative hormone therapies.
A new study by New York University found that a well-designed physical work environment can improve nurses' efficiency, teamwork, and communication, leading to higher job satisfaction. The study also revealed that this indirect impact on job satisfaction is associated with better patient outcomes.
Researchers have identified three genetic changes linked to an increased risk of breast cancer in East Asian women. These findings provide new insights into the genetics and biology of breast cancer.
A 15-year study reveals that blue whales consistently return to specific feeding grounds along the US West Coast, despite busy shipping lanes. The findings highlight the need for modifications in ship routing to reduce human threats to the endangered species.
A new study finds that statin use significantly reduces the risk of developing Barrett's esophagus, with the greatest effect seen in obese patients. Those with a body mass index greater than or equal to 30 had a 74 percent reduction in Barrett's esophagus odds.
The Digital Latin Library will provide access to Latin texts and resources for reading and analysis, while the Library of Digital Latin Texts will support new scholarship and educational materials. The project aims to enhance scholarly endeavors on an international scale and complement other digital initiatives.
Research finds men with wider faces excel in solo negotiations, securing higher bonuses and sale prices, but falter when collaborating or selling to others. In contrast, more attractive men perform better in team settings.
A three-year grant will measure indoor air quality in tents used by Native subsistence hunters in subarctic North America to determine possible health effects of wood smoke exposure. The study aims to provide information on emissions mitigation methods and improve understanding of multipollutant emissions.
A new study found that genetic variations, particularly imprinted genes, play a significant role in determining the age of puberty in girls. The research analyzed DNA data from over 180,000 women and identified six imprinted gene variants associated with earlier or later menstrual cycles.
A recent study published in JAMA Dermatology found that nearly 36.9% of skin cancer lesions are accompanied by itching, while 28.2% involve pain. Non-melanoma skin cancers are more likely to be associated with itch or pain.
A new study published in Neurology suggests that regularly monitoring pulse after a stroke can detect irregular heartbeats and prevent a second stroke. The study found that healthcare professionals had a high sensitivity rate of nearly 97% in detecting irregular heartbeats.
Researchers successfully ran 10,240 parallel simulations of global weather using Japan's K computer, achieving a significant improvement in forecasting accuracy. The study found that faraway observations can have an immediate impact on weather forecasts, highlighting the need for advanced methods to utilize this data.
A multi-center study found significant improvements in medical students' perceptions of their health policy education between 2008 and 2012. The study revealed gains in three domains: systems and principles, value and equity, and quality and safety. However, the domain politics and law experienced a decline due to inadequate training.
The US Department of Defense has awarded a $2.6 million grant to the STEMPREP Project at Southern Methodist University to support its goal of increasing the number of minorities in STEM fields. The program boasts an impressive success rate, with 100% of students attending college and 83% going on to graduate school.
Researchers propose using industrial pollution as a sign of intelligent life, which could be detectable with the James Webb Space Telescope. The team found that CFCs could be used to identify advanced civilizations, but this method requires an ideal environment, such as an Earth-like planet circling a white dwarf star.
Lab tests reveal that oregano and rosemary, commonly used herbs, have potent compounds against type-2 diabetes. Greenhouse-grown herbs contained more polyphenols but required less to inhibit a key enzyme.
A research team has developed a cost-effective technology to synthesize heteroatom (S or N)-doped graphenes, which can be applied as high performance electrodes for secondary batteries and fuel cells. These materials enhance battery performance and drive down the cost of producing fuel cells.
A study by Columbia University School of Nursing found that NPs in Massachusetts have better relationships with physicians and administrators compared to those in New York State. The researchers recommend improving the practice environment for NPs in NY by promoting their role and providing opportunities for involvement in organization...
A new study found that controlling pain during childbirth and post delivery may reduce the risk of postpartum depression. Women who had epidural anesthesia during labor had a significantly lower rate of depression compared to those without pain control.
A study found that implementing an Enhanced Recovery After Surgery (ERAS) program in a community hospital setting reduced length of stay from 6.7 days to 3.7 days without increasing readmissions. The ERAS program also decreased use of opioid analgesia and intra-abdominal infections, resulting in estimated cost savings.
A team of Australian astronomers has created a 'Google Street View' of the cosmos using a novel optical-fibre instrument. By analysing light spectra from 60 points in each galaxy, they can study gas and star movement, young star formation, and old star populations, gaining insights into how galaxies change over time.
Research from University of Illinois expert Ravi Mehta found that people are self-controlled in everyday behavior, but indulge when thinking long-term. Abstract thinking can lead to feelings of missing out, regret, and corrective overindulgence, contradicting common consumer psychology literature.
Researchers developed a new method to estimate magma volume and flow, enabling more accurate predictions of future volcanic eruptions. This technique uses zircon crystals to determine the age and injection rate of magma, providing insights into Earth's crust formation, mineral deposits, and natural resources.
Researchers at Purdue University are using spinach to study photosynthesis and convert sunlight into a clean, efficient alternative fuel. The team has made significant breakthroughs in understanding the protein complex responsible for this process, which could lead to the creation of artificial photosynthesis.
Researchers at University of Southampton found a link between increasing temperatures and reduced wheat yield in India. Warmer nighttime temperatures had the most significant impact on crop yield, highlighting the vulnerability of Indian wheat production to climate change.
Researchers found no difference in cancer incidence between those living near nuclear power plants and the general population. The study confirms raised risks of cancer, particularly leukaemia, for earlier time periods.
The Advanced Technology Large-Aperture Space Telescope (ATLAST) mission aims to study dark energy, the mysterious form of energy that accelerates the universe's expansion. ATLAST would also detect signatures of life in the atmospheres of Earth-like planets and resolve stars in distant galaxies.
A genetic study reveals that climate change has significantly impacted Antarctic fur seals, leading to a decline in the population due to changes in food availability. The seals' ability to adapt is hindered by the lack of heritability of 'fitness genes', resulting in a decrease in survival and breeding success.
Physicist Dr David Robert Grimes has derived equations to explain how guitar techniques manipulate pitch, shedding light on string bending, vibrato, and whammy bars. His research provides insights into the physics behind iconic guitarists' sounds.
New research from North Carolina State University reveals that urban heat is killing red maples by boosting pest populations. Warmer temperatures lead to a 300% increase in young gloomy scale insects, resulting in 200 times more adult scales on urban trees. This stress can also limit tree growth and kill trees.
Researchers found that New Caledonian crows can discriminate between different volumes of water and pass a modified test, previously only achieved by 7- to 10-year-old children. The birds' ability to choose options that displace more water suggests they attend to cause-and-effect relationships.
Researchers found that greater mouse-eared bats can calibrate their inner compass using the polarized light of the evening sky. The bats deviated from the control group when exposed to a 90-degree shifted polarization pattern, indicating they used this visual cue for orientation.
A new investigation by The BMJ raises concerns about the top-selling blood-thinning drug dabigatran, citing withheld company information and potential flaws in regulatory decisions. Key findings suggest that monitoring blood levels could reduce major bleeding risks by up to 30-40%.
A 15-year analysis of blue whale movements off the West Coast found that their feeding areas are bisected by shipping lanes, increasing the risk of injury and mortality. Researchers suggest moving shipping lanes to reduce collisions, similar to a previous study that reduced right whale strikes in the Bay of Fundy.
The Hurricane Imaging Radiometer (HIRAD) will fly aboard a NASA Global Hawk aircraft during the HS3 mission, providing unique observations of sea surface wind speed, temperature, and rain. HIRAD's data will advance understanding and predictability of hurricane intensity, helping to determine maximum wind speed and structure of the vortex.
Mayo Clinic researchers discover a strategy to significantly reduce the risk of tumor development using pretreatment with genotoxic etoposide. This approach establishes an adjunctive therapy to harness the clinical value of iPSC-derived cardiac regeneration, providing a promising breakthrough for heart disease treatment.