A new study by Monash University has shown that gastric banding can lead to remission of diabetes in people who are overweight but not obese. The research, published in The Lancet Diabetes and Endocrinology, found that weight loss surgery significantly improved the condition in over half of participants.
A new concept of Alzheimer's disease, as a spectrum of diseases, raises ethical and policy-related questions. Dr. Karlawish suggests preparing legal providers to assess decision-making ability and offering caregiver training to support those affected by the disease.
A study by Columbia University found that exposure to arsenic in drinking water is associated with decreased intelligence in children, with reduced Full Scale and Working Memory scores of 5-6 points
Researchers from the University of California - San Francisco, led by Margaret Tempero, are part of a national 'dream team' working to accelerate treatment and discoveries for pancreatic cancer. The team aims to turn the deadly disease into a treatable one through targeted approaches and collaborative research.
Researchers at Liverpool University are developing new sensors to detect and measure nuclear radiation in the environment, aiming to locate radioactive sources with greater accuracy and sensitivity. The goal is to monitor sites, prevent releases, and support safe nuclear facility operation, with a focus on improving monitoring and cont...
Researchers develop a new strategy to kill bladder cancer cells by attaching gold nanorods to EGFR proteins, which are overexpressed on these cells. The application of low-intensity laser heat the nanorods, killing the cancer cells without harming healthy tissue.
Studies show that we track people's popularity through brain regions involved in anticipating rewards and emotional evaluation. This is linked to two critical systems: reward learning and social cognition, which scale up with the popularity of an individual.
New research by Andrew Stokes suggests that excess weight in the US substantially increases mortality risk, contrary to previous findings. Using individuals' highest BMI in life to predict mortality rates, Stokes found a 33% attributable risk for overweight and obesity.
Researchers tracked bar-headed geese's remarkable tolerance to low oxygen while exercising at top speed in simulated high altitude conditions. The study found that the birds' hearts can supply more oxygen to their muscles, suggesting adaptations for humans could prevent or treat heart attacks and stroke.
A recent study published in University of Eastern Finland found that the quality of dietary carbohydrates affects fatty acid composition in children's blood. High candy consumption and low high-fibre grain intake were linked to increased oleic acid levels, suggesting a potential role for delta-9-desaturase enzyme.
Tropical Cyclone Ita developed near the Solomon Islands and strengthened into a tropical storm on April 5. NASA satellite imagery revealed strong convection and thunderstorms surrounding its center of circulation near Papua New Guinea.
A recent study published in the Proceedings of the National Academy of Sciences found that the intensity difference between an immune response that stimulates cancer and one that kills it may be minimal. This discovery challenges long-held assumptions about the role of the immune system in preventing and killing cancers.
Researchers at Fox Chase Cancer Center have identified FAK as a potential target for epithelial ovarian cancer treatment. By inhibiting the activity of FAK, they found that STAT3 activation was reduced, suggesting that targeting this enzyme could also inhibit the action of STAT3 in epithelial ovarian cancer cells.
A new study found all classes of obesity in US children have increased over the last 14 years, with more severe forms of obesity rising significantly. The study analyzed data from 26,690 children ages 2-19 and found 17.3% were obese in 2011-2012.
Researchers at Fox Chase Cancer Center have uncovered new insights into the genetic mechanisms that protect against breast cancer during pregnancy. By analyzing the genetic activity of women who had and had not given birth, scientists identified differences in gene expression related to cell differentiation and breast anatomy development.
A study by University of Chicago scientists found that genetic variants associated with enjoying the effects of amphetamine also reduce the risk for developing schizophrenia and ADHD. This suggests a complex role for dopamine in these diseases.
Henry Ford Hospital has implemented a kidney transplant technique using new patient safety standards coordinated by the University of Oxford. The IDEAL framework was used to develop and test the minimally-invasive procedure, which successfully transplanted kidneys in 50 recipients.
Researchers at La Jolla Institute for Immunology have identified a novel interaction between Protein Kinase C-η and CTLA-4, a key immune checkpoint receptor. This finding may lead to new tumor immunotherapy strategies targeting CTLA-4.
The SU2C Phillip A. Sharp Innovation in Collaboration Awards aim to foster synergistic and innovative collaborations among SU2C scientists. The inaugural awards will support five grants totaling $950,000, focusing on projects that enhance the SU2C mission to accelerate cancer treatment development.
A new security system called LatentGesture continuously monitors how a user taps and swipes their mobile device, recognizing differences from the owner's tendencies. The system achieved nearly 98% accuracy on smartphones and 97% accuracy on tablets, making it an effective tool for enhancing mobile device security.
Climate change is forecasted to alter the distribution of southwestern bird and reptile species in the Western United States. The study predicts that nearly half of all reptile species will experience significant distribution losses, including the iconic chuckwalla. In contrast, black-throated sparrows and gray vireos are projected to ...
African-Americans may be at a higher risk for developing Alzheimer's disease due to biologic and cultural factors. Researchers emphasize the need for increased participation of African-American participants in research studies to better understand the disease.
Researchers at Penn State have redefined the Atlantic Multidecadal Oscillation (AMO), finding that its true signal was likely in a cooling phase in recent decades. This shift may have offset some of the anthropogenic warming, resulting in a temporary slowdown in global warming.
The Mayo Clinic uses frozen section analysis during breast cancer lumpectomies, sparing patients the need for repeat surgeries in 96% of cases. This technique significantly lowers the 30-day reoperation rate from 13.2% nationally to 3.6% at Mayo.
Research suggests that humans became less mobile and physically active after the transition to agriculture in Central Europe around 5300 BC. Male bones show a decline in strength and rigidity, indicating reduced mobility and heavy physical work, while female bones exhibit more inconsistent trends.
New research suggests that women who frequently consume fat-free or low-fat milk may reduce the progression of knee osteoarthritis. The study found that joint space width decreased by 0.38mm, 0.29mm, and 0.26mm in women with increasing milk intake.
The BRAIN Initiative aims to map all cell types in the brain, develop methods for large-scale recordings of neuronal activity, and advance computational methods to understand patterned neural activity. The ultimate goal is to shed light on disease processes and suggest new therapeutic approaches.
A new study from Ohio State University found that the NRAS gene produces five different variants, rather than just one original form, which may help improve cancer treatment. The discovery of these variants could lead to the development of more effective drugs targeting the NRAS pathway.
The SU2C-Lustgarten Foundation Pancreatic Cancer Convergence Dream Team aims to develop new therapies using patients' own immune cells to treat pancreatic cancer. The team, led by experts in various institutions, will focus on understanding the tumor microenvironment and developing therapeutic agents to eliminate barriers to treatment.
A daily serving of pulses can significantly lower LDL 'bad' cholesterol by five per cent, translating to a five to six per cent reduction in the risk of cardiovascular disease. North Americans would need to more than double their current pulse intake to achieve this benefit.
A Wayne State University professor has received a nearly $1.7 million grant from the National Institutes of Health to investigate proteasome and parkin as potential pharmaceutical drug targets for treating methamphetamine-abuse related neurotoxicity.
The BOSS study uses quasars to map density variations in intergalactic gas, tracing the structure of the young universe and illuminating the nature of dark energy. The latest results establish the expansion rate at 68 km/s/Mly at redshift 2.34 with unprecedented accuracy of 2.2 percent.
Researchers at Oregon State University have discovered a way to convert cellulose from trees into nitrogen-doped nanoporous carbon membranes, used in high-power energy storage devices called supercapacitors. This single-step reaction could enable mass production of these devices at lower cost.
A nationwide study found that parents or caregivers were physically injured in over a third of domestic violence cases, yet only 2% of offenders faced jail time. Children experienced fear, anxiety, and trauma more often than physical harm.
A study published in the Canadian Medical Association Journal found that eating just 1 serving of legumes daily can significantly reduce LDL cholesterol by 5%. This reduction may lead to a 5% lower risk of major vascular events. The authors suggest that increasing pulse intake is a reasonable and beneficial dietary change.
Researchers at NC State University found that organic solar cell efficiency improves when donor and acceptor molecules are aligned face-on, rather than edge-on. This alignment enables favorable charge transfer interactions, reducing recombination and increasing power generation.
Research published in Psychological Science found that procrastination and impulsivity are genetically linked, with a complete genetic overlap between the two traits. This suggests that procrastination may be an evolutionary byproduct of impulsivity, manifesting itself more in modern times.
Research published in PNAS identifies the insula as a key brain region disrupted in individuals with gambling addiction. The study reveals that problems gamblers are more susceptible to cognitive distortions, such as the gambler's fallacy, due to insula hyperactivity.
The Farrah Fawcett Foundation is supporting a new $1.2 million research team to develop vaccines and immunotherapies for HPV-driven cancers, which currently have few therapeutic options. The team aims to identify tumor targets, activate specific immune cells, and deploy them at the tumor site for selective destruction of cancer.
Researchers at the University of Helsinki found that vitamin B3 form, nicotinamide riboside, can delay the signs of mitochondrial myopathy in animal models. The treatment increased mitochondrial mass and function, curing structural abnormalities and providing a potential therapeutic approach for adult-onset mitochondrial muscle diseases.
Scientists have discovered the atomic-scale mechanism of action for NpmA, an enzyme that imparts chemical changes to bacterial ribosomes, making them resistant to aminoglycoside antibiotics. This finding poses a significant threat to public health, but also reveals potential targets for developing new drugs.
Researchers explore new approaches to managing intraocular fluid buildup in the trabecular meshwork, a key structure controlling eye pressure. The development of next-generation glaucoma therapies aims to improve treatment options for those at risk of glaucoma.
Researchers from Universidad Carlos III de Madrid find that price controls can increase efficiency and lower prices for generic medicines. The study suggests alternative instruments to direct regulation, promoting competition and transparency.
A recent study found that paternal obesity may be a greater risk factor for autism spectrum disorder in children than maternal obesity. The research analyzed data from over 90,000 Norwegian children and found a doubled risk of developing autism if the father was obese compared to a normal-weight father.
A study of 10,000 students found that remedial courses at community colleges can help earn an associate's degree, but taking three or more remedial courses at four-year colleges may hold back students from earning a bachelor's degree. Researchers from Boston College analyzed federal data and discovered that developmental education at t...
Researchers at Dartmouth found that disrupting VISTA, a protein preventing overreaction, enhanced the immune system. This discovery may lead to new cancer treatments using the immune system.
The Bezos family's $20 million donation will support the development of novel cancer immunotherapies for various solid tumor cancers. The gift promises to save lives by expanding the use of immunotherapy to treat a range of deadly cancers.
A new study reveals that feelings of failure and frustration during video game play are the primary causes of aggression, not violent content. The research found that players' experiences of mastering a game's controls and degree of difficulty led to frustration and hostility.
Researchers found that individuals with private insurance were more likely to secure a new-patient appointment with a primary care physician compared to those with Medicaid or no insurance. The study suggests that the primary care system may struggle to handle increased demand from ACA coverage expansions, highlighting the need for pol...
A study by Johns Hopkins Bloomberg School of Public Health found that cognitive impairment affects seniors in both nursing homes and the community, with patients lacking advance directives receiving aggressive care. Advance care planning is essential to ensure desired treatments are followed.
Researchers found that integrating URI education into Early Head Start programs led to a decline in pediatric emergency visits and adverse care practices among predominantly Latino families. The intervention showed promise in addressing health literacy gaps, with significant reductions in over-the-counter medication misuse.
A study found that teenage drivers with a higher response to stress, as measured by cortisol levels, had lower crash and near-crash rates. Cortisol levels were measured at baseline and over time from saliva samples, and in-vehicle cameras and sensors allowed continuous observation of driving.
A team of researchers in Kenya and Brown University will test a community-based breastfeeding support initiative with a $450,000 grant. The three-year pilot aims to improve nutrition and health status among 1,000 mother-child pairs in rural Igembe North.
The I-SPY 2 trial found that neratinib-based treatment improved outcomes for women with newly diagnosed, high-risk breast cancer. The adaptive randomization algorithm successfully identified patient subgroups likely to benefit from the regimen.
A new study explains how DNA methylation protects duplicate genes, allowing them to evolve into new cellular functions. The research found that young duplicate genes are heavily methylated, shielding them from natural selection.
A new study by Brown University researchers found that hospital attending physicians' specialties are linked to the likelihood of patients receiving gastric feeding tubes, which is not recommended for frail, terminal patients. The study analyzed tens of thousands of cases over a decade and found that patients cared for by primary care ...
Scientists at Scripps Research Institute have discovered a new binding site on peroxisome proliferator-activated receptor-gamma (PPARG) that could lead to improved insulin-sensitizing drugs. This alternative site may provide clues to the adverse effects of existing anti-diabetic medications, such as bone loss and congestive heart failure.
A study published in Neurobiology of Aging has found a connection between the integrity of white matter connections in the brain and cognitive health in adults with Down syndrome. The research team identified biomarkers connected to dementia, including Alzheimer's disease, which could potentially lead to earlier intervention and retard...
A study reveals that nearly one-third of ADHD-diagnosed foster care youth aged 2-17 received atypical antipsychotics, highlighting a critical trend in pediatric psychiatry. The most common medications given were risperidone, aripiprazole, and quetiapine.
A recent study examined the impact of state Medicaid expansions on perceived access to care and emergency department use among enrollees. The results showed no evidence that expanding Medicaid coverage eroded access to care or increased ED use, contrary to previous concerns.