The Journal supplement highlights innovative approaches to healthy aging, including community-based efforts, technology uses, and civic service. Strategies like Experience Corps and volunteering are shown to enhance social engagement, independence, and well-being in older adults.
A recent study suggests that emissions from human activity have caused a decline in monsoon rainfall over the past 50 years. The research, published in Geophysical Research Letters, found that rising levels of anthropogenic aerosols are responsible for the decrease, which affects billions of people primarily in India and parts of Africa.
University of Minnesota researchers have identified microRNAs miR-182 and miR-503 that contribute to the development of colon polyps into cancerous tumors. By targeting these microRNAs, physicians may be able to provide earlier and more specialized treatment for patients with a higher risk of colon cancer.
A new genetic test developed by scientists can detect canine fecal contamination in water, providing insights into the scale of the problem. The test identified 11 genetic markers common to most dog samples but absent from human ones, revealing the significant role dogs play in contaminating US waterways.
Sick mice produce specialized sugars to feed their gut microbiota and resist infection. Healthy recovery requires both L-fucose production and intact gut microbiota. The study suggests a potential role for L-fucose in preventing or tolerating Crohn's disease.
Researchers conducted life history interviews with 26 health workers who lived through conflict in Northern Uganda, revealing their resilience and coping mechanisms. The study proposes solutions to protect and motivate health workers during and after crises, including community support, formal promotion, and regular pay.
A genetic study suggests that individuals with a specific genotype may be prone to weight gain and increased risk of diabetes and heart disease when exposed to chronic stress. Simple interventions like healthy diet, exercise, and stress management could help reduce the risk of cardiovascular disease in these individuals.
Researchers have successfully treated a genetic form of intellectual disability in mice using an anticancer drug, suggesting a potential new approach for the human condition. The study's findings indicate that altering the balance between chromatin's open and closed states could be key to treating Mendelian disorders of the epigenetic ...
A new study found that providing free contraception and education on various methods significantly reduced teen pregnancies, births, and abortions. Among participants, 72% opted for long-acting forms like IUDs or implants, leading to a 34-per-1,000 pregnancy rate among teens compared to 158.5 in 2008.
New research suggests that long non-coding RNAs play a crucial role in regulating the human immune system's response to infection. The study reveals how these molecules can promote, fine-tune, and restrain the body's inflammatory response by controlling gene expression.
Scientists at Cincinnati Children's Hospital Medical Center developed a new cell transplantation therapy to treat mice with a rare lung disease. The therapy, using macrophages, corrected the disease in mice and showed promise for treating other human lung diseases caused by dysfunctional immune cells.
An international study found that introducing gluten at different ages has no effect on developing celiac disease, and genetic factors are the primary risk factor. The study's results suggest a blood test for HLA genotype could determine high-risk infants, paving the way for preventive interventions.
Researchers have identified a novel source of stem cells in the corneal limbus that can be directed to behave like photoreceptor cells, potentially treating conditions like age-related macular degeneration. These cells can also be cultured from older eyes and may offer a promising approach for new treatments.
New research published in the BMJ suggests that long-acting insulin is superior to intermediate-acting insulin for controlling blood sugar levels, preventing weight gain, and treating severe hypoglycemia. Long-acting insulin also showed improved cost-effectiveness compared to intermediate-acting insulin.
A study published in Science Signaling found that JAK inhibitors can effectively treat over 80% of bowel cancers with a genetic mutation present in more than 80% of cases. The researchers discovered that these inhibitors block tumour growth by targeting the Wnt signaling pathway, with minimal impact on normal cells.
Researchers have identified a molecular mechanism that could explain why the common cold can bring on life-threatening asthma attacks. A small molecule called IL-25 may play a central role in triggering these attacks, and blocking it could potentially produce a much greater therapeutic effect.
The National Science Foundation is investing $31 million in 17 innovative projects to develop tools, cyberinfrastructure, and best practices for data science. These projects aim to create a robust national data infrastructure that supports research priorities and emerging data policies.
A new study from the University of Melbourne found that acupuncture did not improve chronic knee pain in patients older than 50. The research, published in JAMA, involved 282 participants who received either real or sham acupuncture for 12 weeks.
Researchers found that Montmorency tart cherry juice lowered blood uric acid levels and increased specific anthocyanin compounds, which may help alleviate joint pain and inflammation associated with conditions like gout. The study also detected increased C-reactive protein in the bloodstream after consuming tart cherries.
Fish larvae produce distinct 'knock' and 'growl' sounds within the hearing range of adult fish to maintain group cohesion during their pelagic journey. The sounds were observed in 70% of nighttime trials, suggesting a mechanism for larval communication.
A team of researchers will study the complex connections between brain cells that allow us to make and retrieve lasting memories. The project aims to build a complete computational model of a neural network in vertebrates using experimental data, with potential transformative insights into mammalian brain abilities.
Scientists at The University of Nottingham have made a major medical discovery that could lead to the development of an entirely new type of painkiller for chronic pain conditions like traumatic nerve injury. They found that a signal protein called VEGF promotes pain while its inhibiting form prevents it.
A study of Medicare data found that hospitals with high care intensity had lower failure-to-rescue rates after major surgery, but longer hospital stays. However, patients treated at these hospitals also experienced higher inpatient deaths and reduced hospice use.
Researchers propose a new method for measuring magnetic properties of materials at atomic resolution, utilizing the phase symmetry of an electron beam. This technique enhances the magnetic signal, enabling the detection of magnetism with unprecedented precision.
The Global AgeWatch Index highlights disparities in the wellbeing of over-60s worldwide, with Norway and Sweden leading the top five. Many countries, particularly in low-income regions, face challenges in providing adequate support for their aging populations.
Researchers at Concordia University found that individuals with less variable heart rates when worrying are more likely to experience high stress levels later on. This diagnostic measure can help healthcare professionals identify those most susceptible to chronic stress and provide timely interventions.
A team of Clemson University researchers will use a $5.25 million grant from the US Department of Energy to advance nuclear monitoring, remediation and disposal technologies in South Carolina. The project aims to address key scientific issues related to radioactive contaminants and develop integrative models for radionuclide transport.
A University of Utah study reveals benzodiazepines increase ICU mortality by 9.1% compared to propofol. Patients treated with benzodiazepines spent more time on mechanical ventilation and were at higher risk for complications like delirium.
A team led by Drs. Mary L. Marazita and Seth M. Weinberg will recruit 6,100 individuals for genetic studies to identify genetic susceptibility for cleft lip and palate in low-risk populations in Nigeria, the Philippines, and Colombia, as well as mid-risk populations in Pittsburgh and Lancaster.
Researchers at Lund University have discovered a new learning mechanism in individual nerve cells, which enables the brain to time its reactions and control complex processes like blinking and intelligible speech. This discovery has significant implications for rehabilitation following stroke, autism, ADHD, and language problems.
Researchers have successfully developed a synthetic version of the sperm protein PAWP, which induces calcium oscillations and oocyte activation in human and mouse eggs. This breakthrough raises hopes for improved IVF success rates and better understanding of fertilization events.
Tropical Storm Rachel is spinning down west of Mexico's Baja California, with another tropical low pressure area, System 90E, outgrowing it. The National Hurricane Center predicts that System 90E will intensify into a tropical depression by Wednesday, Oct. 1.
CWRU researchers are investigating how patients make end-of-life decisions, with a focus on improving the quality of life for patients and their loved ones. The four-year study aims to better understand the complex interactions between healthcare professionals, caregivers, and patients in making these decisions.
Researchers have made a breakthrough in understanding how birds evolved from dinosaurs by studying fossil and developmental data, revealing the fusion of two bones to form a semilunate bone. The study clarifies the identity of wrist bones in both groups, shedding light on the evolutionary reversal of a lost bone.
A study found that a type of gut bacteria called Clostridium ramosum promotes obesity in mice, particularly when fed a high-fat diet. The bacteria appears to improve nutrient uptake, leading to increased energy conversion and weight gain.
Harvard University researchers demonstrate ability to paint ultra-thin coatings onto rough surfaces using thin-film interference, enabling lightweight decorative logos on spacecraft. The technology also holds promise for making flexible electronic devices and advanced solar cells.
Four CSHL scientists will conduct research in the Brain Research through Advancing Innovative Neurotechnologies Initiative, aiming to map the human brain and understand brain disorders. The initiative seeks to develop transformative tools for studying the brain's structure and function.
A new study published in the FASEB Journal reveals never-before-detected gene activity and sex differences in human skeletal muscle. The research found that men have approximately 400 more active genes than women, providing a reference for future studies on muscle disease and dysfunction.
A study by Chapman University's Food Science Program has identified 20 commercial pet foods that were potentially mislabeled, containing undeclared meat species such as pork. The research focused on the presence of eight meat species in dog and cat food products, with chicken being the most common detected species.
A comprehensive study found that medications are the leading cause of allergy-related sudden deaths in the US, particularly among older people and African-Americans. The study analyzed death certificates from 1999-2010 and identified antibiotics as the most common culprit drug.
A study analyzing medical professional liability claims related to esophageal cancer screening found that the risks of claims arising from acts of commission and omission are similarly low. The authors suggest that physicians balance the risk of complications from diagnostic procedures, even if those complications are rare.
A new study found that countries with greater parity in measures of educational equality had more women and men reach the podium at the London 2012 and Sochi 2014 Olympic Games. The researchers suggest that gender stereotypes may limit the number of women and men viewed as potential high-performance athletes.
A new virtual breast test using ultrasound elastography could significantly improve cancer detection accuracy, especially for women with suspicious mammograms.
A gene mutation that causes a rare premature aging disease could lead to the development of drugs that block rapid cell division in cancer. Researchers discovered a protein mutation that inhibits telomerase, allowing for the potential treatment of cancer and bone marrow failure.
A new study from Harvard, Syracuse, and Boston University scientists reveals that strong carbon standards for power plants can significantly reduce air pollution and provide substantial human health benefits. The research estimates that such standards could prevent thousands of premature deaths and hospitalizations every year in the US.
The Rosetta spacecraft has woken up from its 957-day hibernation, sparking jubilation among scientists and engineers. The mission aims to unlock the mysteries of how our solar system formed and developed into what we see today.
The NASA Swift satellite detected a series of powerful stellar flares from the nearby red dwarf star DG CVn, with temperatures reaching 360 million degrees Fahrenheit. The flares were triggered by rapid spin and amplifying magnetic fields, making them one of the longest-lasting events ever recorded.
Researchers at Salk Institute will create an epigenetic map of each cell type in the brain, allowing for deeper understanding of neurons' identity and functional differences. The study aims to reveal possible windows into brain development and disease.
A new study reveals TMS treatment normalizes hyperconnectivity in the DMN, while leaving CEN connectivity unaffected. The treatment may act by selectively regulating network-level connectivity.
Researchers have identified a bacterial breakdown pathway for diazepam in UK rivers, which could reduce its potentially harmful impact on the environment. The study found that bacteria can break down diazepam's photo-degradation product, ACB, into small natural molecules, including ammonium.
Researchers at University of Cincinnati discover that electroencephalography (EEG) electrodes on the scalp can measure spreading depolarizations in injured brains, which are associated with worse outcomes. This non-invasive technique has the potential to revolutionize bedside neuro-monitoring.
Researchers develop a new liquid-phase 3D printing technique that allows for the rapid manufacturing of conductive metal objects with a low melting point alloy ink. The process prevents oxidation and offers advantages over conventional methods, including high speed and flexibility in controlling temperature and flow fields.
Researchers found that combining resveratrol with benzoyl peroxide reduces bacteria counts more effectively than either compound alone. The combination treatment may lead to new, less irritating topical acne therapies.
A minimum unit price of 45p would significantly reduce consumption and health harms among harmful drinkers, with effects estimated at 40-50 times greater than a below cost selling ban. This policy is likely to save thousands of lives and hospital admissions per year.
The new guidelines emphasize the effectiveness of levothyroxine in most patients with hypothyroidism, but note that some individuals may not regain optimal health. Alternative treatments are also discussed, but no consistently strong evidence supports their superiority.
Researchers at Trinity College Dublin discovered a mechanism called 'mutational robustness' that explains how gene duplication leads to novel functions and survival across long evolutionary timescales. This breakthrough has implications for understanding genome evolution and the importance of redundancy in organisms.
Researchers discover six unique states of pneumococcus bacteria, which can help develop tailored vaccines. The study found that each state has distinct DNA methylation patterns and alters gene expression, virulence, and disease severity.
A study by Max-Planck Institute found that great tits' risk-taking behaviour correlates with both metabolic rate and ambient temperature. Birds with high metabolic rates and low temperatures were more likely to approach predators.
A study by San Diego State University professor Jean M. Twenge found that Americans now report more psychosomatic symptoms of depression than their counterparts in the 1980s. These symptoms include trouble sleeping, concentration difficulties, memory problems, feeling overwhelmed, restless sleep, poor appetite, and lack of motivation.
Researchers at Brown University created a culturally compatible diagnostic approach for autism in Tanzanian children. The approach uses a collection of instruments adapted from established tools, including the Childhood Autism Rating Scale-Second Edition (CARS-2) and Malawi Development Assessment Tool.