A new Penn Medicine study found that dopamine replacement therapy is associated with an increase in impulse control disorders and excessive daytime sleepiness in newly diagnosed Parkinson's disease patients. In contrast, fatigue improved with dopamine therapy, but depression remained undertreated.
A new study reveals seven tiny pieces of interstellar dust found in samples collected by the Stardust Interstellar Dust Collector, which traveled through space and returned to Earth in 2006. The discovery allows researchers to study contemporary stardust for the first time on Earth.
Hurricane Karina's vertical wind shear was evident in NASA imagery captured on August 14, with clouds being pushed to the western side of the storm. The National Hurricane Center predicts further weakening over the next two days as Karina moves over sea surface temperatures near 26C.
Researchers at Baylor College of Medicine have successfully incorporated a cream supplement into premature infants' diets, improving their growth outcomes in the NICU. The study found that adding human milk fat to an exclusive human milk diet enhanced weight and length gain in premature babies, indicating improved lean mass growth.
A new study from the University of Exeter challenges traditional views on magpie behavior, finding that these birds are not attracted to shiny objects. Instead, they exhibit neophobia, or fear of new things, when encountering novel and unfamiliar items.
Researchers at the University of Edinburgh have validated a set of guidelines that identify girls with cancer most likely to enter early menopause. These criteria will help select patients for ovarian tissue freezing, potentially allowing young cancer survivors to have children in the future.
The NIH Follow that Cell Challenge seeks tools to monitor a cell's behavior and function over time, potentially leading to earlier diagnosis and improved therapies for diseases. The challenge aims to generate creative ideas and methods for following a single cell's behavior, using multiple integrated measures.
More than 500 delegates from 62 countries have issued a call to action to address the impacts of climate change on human health and the global environment. The ecohealth community has developed a vision and commitment to action that will bring together existing efforts to respond to climate change.
Researchers will use innovative approaches to study how genetic sequence changes affect cells in the body, leading to diseases such as obesity, diabetes, and heart disease. The goal is to develop new therapies and improve treatment for these conditions.
Researchers have found that an antibody against EphA3 can slow tumour growth and kill cancer cells by disrupting blood vessels and the tumour micro-environment.
Researchers investigate possible Galileon-like theories with new kinds of symmetries, potentially describing systems near multi-critical points and superfluids. Non-relativistic systems like Goldstone bosons are also considered for potential applications.
SRAP markers exhibit high variability and are less technically demanding than traditional methods, making them suitable for various research fields including plant systematics, biogeography, conservation, and ecology. The new study suggests that these markers will be useful when paired with next-generation sequencing technologies.
Patients with low vitamin D levels are at increased risk of death and serious complications after noncardiac surgery. Higher vitamin D concentrations were associated with decreased odds of in-hospital mortality/morbidity, but the association was only statistically significant for cardiovascular complications.
The Lindau Meeting on Economic Sciences brings together Nobel laureates and young economists to discuss the scope of incentives, innovation, and growth. The meeting will explore how to encourage mass flourishing and dynamism in economics.
Researchers found an association between over-estimating medication self-administration ability and memory loss among stroke survivors. Assessing patients for their ability to estimate medication skills accurately may predict memory disorders.
Researchers at PRB, WSU, and DMC identify preterm labor as a syndrome caused by multiple disease states, including silent infections and maternal anti-fetal rejection. Studies show that administering vaginal progesterone can reduce preterm birth rates by 45%, highlighting potential therapeutic interventions.
A new algorithm developed by Hua-Wei Shen helps accurately allocate credit to researchers based on their contributions. The algorithm, which has been tested on 63 Nobel prize-winning papers, found that authors deserving of the most credit corresponded to the Nobel laureate in 81% of cases.
A large pooled analysis of seven studies involving over 25,000 individuals found associations between lung cancer and chronic bronchitis, emphysema, and pneumonia. Patients with co-occurring chronic bronchitis, emphysema, and pneumonia had a higher risk of lung cancer.
A new study by the University of British Columbia found that changes to B.C.'s impaired driving laws reduced fatal crashes by 21%, hospital admissions by 8% and ambulance calls by 7.2%. The study attributes these reductions to stricter penalties for impaired driving.
A UCSF study found significant price differences in common blood tests across California hospitals, with prices ranging from $35 to $7,303. Hospital ownership and teaching status explain some variation, but factors like location and labor costs do not.
New research suggests that bats' brains use the temporal binding hypothesis to focus on targets in cluttered scenes, which could inspire new navigation technology. By studying bat echolocation, scientists have developed a better understanding of how to design radar and sonar systems for real-time performance.
A recent study found that using active questioning techniques can significantly improve the accuracy of lie detection in interrogations, with experts achieving near-perfect results (97.8%) compared to non-experts. This suggests that simply watching or listening is not enough for effective deception detection.
Researchers at TUM developed TCP Stealth, a free software that inhibits identification of systems through Hacienda and similar cyberattack software. The software uses secret tokens to protect against remote control of servers worldwide.
Researchers found that gut bacteria can sway food choices by releasing signaling molecules into the gut, influencing physiological and behavioral responses. The microbiome's diversity of interests can be manipulated through diet and supplement changes, offering a tractable approach to obesity and unhealthy eating.
Researchers discovered that beetle scales scatter light efficiently to achieve ultra-whiteness, using a complex network of chitin filaments. This finding could lead to brighter, whiter materials for paper, plastics, and paints while reducing material usage.
Broadly neutralizing antibodies, combined with viral inducers, have been found to control HIV in mice by targeting latent reservoirs of infected cells. The approach, called "shock and kill," resulted in a 57% success rate in preventing viral rebound.
A new study found an inverse relationship between phthalate exposure and testosterone levels in various populations, including boys ages 6-12 and men and women ages 40-60. Increased phthalate concentrations were associated with a decline in testosterone levels, potentially impacting reproductive development and sexual function.
Researchers used CRISPR/Cas9 to correct genetic mutations leading to Duchenne muscular dystrophy in a mouse model, preventing progressive muscle weakness and degeneration. The technique may lead to permanent correction of the disease, offering hope for future therapeutic applications.
Research highlights the effectiveness of blood pressure-lowering treatment based on cardiovascular risk, as well as the importance of predicted baseline risk equations. Additionally, studies investigate the use of bivalirudin versus heparin in percutaneous coronary intervention and implant-based multiparameter telemonitoring for heart ...
A recent study from the University of Bergen found that 8.3 percent of the Norwegian workforce is addicted to work, with no differences between men and women. The study used a nationally representative sample of 2,160 participants and identified seven criteria to measure work addiction.
Research at the Center for BrainHealth found that risk-taking teens exhibit hyperconnectivity between the amygdala and prefrontal cortex, indicating an imbalance in emotional regulation. This imbalance may be associated with increased activity in the nucleus accumbens, a center linked to reward sensitivity.
Researchers have discovered an enzyme therapy that improves bone growth, mineralization, and strength in a mouse model of neurofibromatosis type-1. The treatment, asfotase-alpha, reduces fractures by clearing accumulated pyrophosphate, a strong inhibitor of bone mineralization.
Researchers found that rats with no explicit memory of an early childhood trauma developed PTSD symptoms, highlighting the importance of non-articulated brain processes in distress. This study challenges traditional views on PTSD treatment by emphasizing the role of physiologic arousal and other forms of learning.
A thermosensitive collagen hydrogel was used as an extracellular matrix to construct tissue-engineered peripheral nerve composites in vitro. The results showed that seeded cells maintained larger numbers and were well-distributed throughout the material, improving the construction of tissue-engineered peripheral nerves.
Researchers at Washington University School of Medicine have identified a potential new class of drugs, histone deacetylase inhibitors, that can dissolve kidney stones by reducing calcium and magnesium levels in the urine. The study shows promising results using small doses of two specific drugs, Vorinostat and trichostatin A.
Researchers found that a husband's declining health increases his wife's glucose levels, while a widowed spouse only affects men's blood sugar control. Caregiving demands on married women may lead to poor eating habits and inadequate glucose control.
Researchers have identified a 52-character biological signal specific to bacterial infection in newborns' DNA, enabling early detection and diagnosis. This breakthrough could lead to the development of a single-drop blood test, limiting antibiotic overuse and tackling drug resistance.
Researchers have discovered a key enzyme involved in O-glycosylation of LDLR, a receptor protein responsible for absorbing bad cholesterol. The study provides new insights into the functional impact of glycosylation on cholesterol levels.
Researchers at the University of Adelaide found that a child's future health is shaped by more than genetic material. Stored environmental factors in eggs and sperm can influence development, leading to a higher risk of metabolic diseases, anxiety, and immune dysfunction.
Researchers discover that 12-lipoxygenase (12-LO) enzyme promotes pre-diabetes and diabetes by causing oxidative stress in pancreatic cells. The study shows that a high-fat diet leads to the production of harmful molecules, ultimately damaging the cell's ability to produce insulin.
Scientists discovered that the Hippo pathway, a tumor suppressor pathway, senses abnormal chromosome numbers in cells and triggers cell cycle arrest. This pathway prevents progression into cancer by halting the proliferation of tetraploid cells with double the number of chromosomes.
A team of astronomers has created new maps of the interstellar medium in the Milky Way, revealing clues about the composition and distribution of mysterious complex molecules. The findings could provide insights into how stars form and the conditions that lead to their creation.
A new study by Johns Hopkins Medicine found that nearly one in ten inner-city children has a food allergy, with breastfed kids and high exposure to endotoxin being potential risk factors. The study also highlighted a subgroup of children with higher-than-average allergy risk.
Researchers at Australian National University developed a technique to cool nanowire probes with lasers, increasing their sensitivity 20 times and enabling detection of tiny forces. This could improve the resolution of atomic force microscopes, measuring nanoscopic structures and molecular interactions.
Tropical Storm Karina formed in the Eastern Pacific on August 13 near Socorro Island, strengthening from a 11th tropical depression. The storm's maximum sustained winds were near 40 mph with an estimated minimum central pressure of 1005 millibars.
A new virus-like particle vaccine has shown promising results in a human trial, generating antibodies that provide long-term protection against chikungunya. The vaccine, composed of non-infectious VLP particles, was well-tolerated and effective across different doses.
Researchers have found that plants can exchange thousands of mRNA molecules, allowing them to freely communicate and potentially dictate what the host plant should do. This discovery could lead to new strategies for controlling parasitic weeds that affect food crops in poor regions.
Researchers at Aalto University found that users fake parts of their online image to be accepted by others. Despite this, sharing authentic content is often hindered by a fear of being perceived as excessive or attention-seeking. This paradox highlights the complexities of presenting an authentic image on social network sites.
Researchers have identified a small molecule capable of interrupting the disease process in cells carrying the C9ORF72 gene, a variant associated with ALS and FTD. The compound selectively targets abnormal RNA molecules, reducing their accumulation and potentially serving as a biomarker for clinical trials.
A comprehensive review article reveals shared nervous system mechanisms governing mammalian parental motivation, including the role of oxytocin and testosterone. This understanding can lead to improved social development and benefit future generations of humans and animals.
Researchers found that mountain lions in the Santa Monica Mountains have dangerously low genetic diversity due to near complete isolation by freeways. Only one young lion successfully dispersed into the area over a decade, highlighting the need for increased connectivity.
Research by Kurt Ingeman at Oregon State University shows that lionfish exhibit alarming behavior, staying in one area and consuming prey even when numbers are low. This makes them more formidable predators than native species, threatening local extinction.
The cytoplasm of mammalian cells is actually an elastic gel that creates random waves due to energetic processes in the cell. This new understanding provides a snapshot of the metabolic state of the cell and raises questions about cellular dynamics.
Researchers found that patients taking COX2 inhibitors, such as aspirin or ibuprofen, had a lower breast cancer recurrence rate compared to those not taking these medications. This reduced the risk of ERα positive breast cancer by 50% and extended disease-free periods by more than two years.
A study by the Endocrine Society found that women with vitamin D deficiency were nearly half as likely to conceive through IVF as those with sufficient levels. Women with adequate vitamin D levels had higher-quality embryos and increased chances of successful implantation.
Research finds that parasitic nematodes use olfaction to locate hosts, with distinct odor profiles reflecting host specificity rather than relatedness. The study's findings suggest targeted traps or repellents could be developed to control nematode infections.
Researchers at the Salk Institute have identified a key control mechanism on regulatory T cells that maintain immune system balance. Removing a specific genetic sequence in Foxp3 destabilizes these cells, leading to autoimmune disease in animal models.
A strong association has been found between severe untreated obstructive sleep apnea and the risk of elevated blood pressure despite aggressive medication use. The odds of resistant elevated blood pressure were four times higher in participants with severe sleep apnea.
A new study in the Annals of Global Health highlights the urgent need for substance abuse programs in developing countries. The study calls on policymakers to design effective programs that meet known population needs, adapting models like Alcoholics Anonymous to fit different cultural norms.
Researchers create RNA origami structures by encoding folding recipes into single-strand RNAs, allowing for self-folding and organization of molecules on the nanoscale. The method has potential applications in cellular engineering, biochemical factories, and molecular scaffolds.