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Science News for August 17, 2014


BGRF announces OncoFinder algorithm for reducing errors in transcriptome analysis

The OncoFinder algorithm reduces errors in transcriptome analysis by mapping gene expression onto signalling pathways, allowing for more effective evaluation and analysis. The method enables scientists to characterise functional states of transcriptomes more accurately, improving research and clinical applications.

SourceBiogerontology Research Foundation·JournalFrontiers in Molecular Biosciences·DateAug 17, 2014

Microchip reveals how tumor cells transition to invasion

Researchers have shed new light on the epithelial-mesenchymal transition (EMT) process in cancer cells, using a microengineered device that acts as an obstacle course for cells. The study reveals that EMT upgrades cancer cells from an economy model to a fast sports car, allowing them to migrate aggressively to distant locations.

SourceBrown University·JournalNature Materials·DateAug 17, 2014

DNA methylation involved in Alzheimer's disease

Researchers at Brigham and Women's Hospital discovered that early changes in brain DNA methylation are involved in Alzheimer's disease. The study found correlations between methylation levels and Alzheimer's disease in specific genes, suggesting a potential role for epigenomic modifications in disease susceptibility.

SourceBrigham and Women's Hospital·JournalNature Neuroscience·DateAug 17, 2014