The new guideline aims to reduce unnecessary re-excision rates by identifying optimal margin widths that minimize ipsilateral breast tumor recurrence. Wider margin widths do not significantly lower the risk, and the choice of radiation technique should not depend on margin width.
Researchers discovered that ants' neck joints can withstand pressures of up to 5,000 times the ant's weight due to a unique combination of soft tissue and hard exoskeleton materials. This finding could lead to the development of micro-sized robots with improved mechanical functionality.
A new study confirms that big-city legislation is passed at lower rates than smaller bills, citing infighting within city delegations as the primary cause. Despite larger representation, urban areas struggle to pass legislation due to internal divisions and party politics.
Researchers found that aggression genes control dominance in wasps, while also being linked to fighting behaviors in bees, fruit flies, and mice. External environment plays a crucial role in shaping gene expression, suggesting a stronger influence of nature over nurture.
Researchers at NIST and American University suggest changes to the common furniture fire test to make it more realistic, focusing on air flow and foam materials. The modifications aim to identify upholstery materials most likely to prevent smoldering ignition, with potential implications for fire safety regulations.
Researchers found distinct spectral signatures of ferric and ferrous minerals at most RSL sites, suggesting a possible connection to water. However, the lack of water-related absorptions rules out hydrated salts as a dominant phase on RSL slopes.
A 18-month pilot program increased the time people with dementia lived successfully at home, with participants receiving in-home care coordination and education. The trial found significant improvements in quality of life, safety, and reduced need for nursing homes.
Researchers have developed nanoparticles that can efficiently silence target genes in the liver, showing promise for treating cancer and other diseases. The new particles, inspired by lipoproteins, achieve gene knockdown with a small amount of RNA, minimizing side effects in other tissues.
Researchers found that chronic lead intoxication impairs therapeutic effectiveness of antibiotic amoxicillin in goats, leading to lower serum concentrations and faster excretion. The study suggests that lead-intoxicated goats may require more frequent amoxicillin administration for effective therapy.
A study of 55 patients treated for flu at Duke University Hospital found that unvaccinated young adults had severe cases and required intensive treatment. The findings highlight the importance of vaccination in reducing severity and preventing costly hospitalizations.
A TGen study has uncovered possible genetic origins of breast cancer that spreads to the brain, providing potential new methods of diagnosis and treatment. The study identified common genetic alterations linked to key mechanisms of cancer, such as cell proliferation and cell-cycle progression.
Researchers at the Stowers Institute discovered that Ndc1, a conserved nuclear envelope protein, works with Mps3 to regulate insertion sites into the nuclear membrane. The team found that Mps3 helps shuttle Ndc1 to specific locations in the nucleus, controlling the distribution of critical structures.
Researchers at NYU Langone Health have found a biological weakness in mutant K-Ras, the most commonly mutated gene involved in human cancers. By blocking the activity of related genes H-Ras and N-Ras, chemotherapy drug irinotecan can stall tumor growth.
Researchers at Curtin University have found a way to breed disease-resistant wheat, reducing yield loss due to Yellow Spot and other diseases. This new technology allows for improved disease resistance without affecting yields or increasing costs.
A study published in the Journal of Traumatic Stress found that Congolese refugees who practiced Transcendental Meditation experienced a significant reduction in posttraumatic stress disorder (PTSD) symptoms after just 10 days. Their PTSD test scores dropped to an average of 48, indicating nearly no symptoms of PTSD.
A study by St. Jude Children's Research Hospital identified an immune signature that predicts poor flu outcomes in patients, who are more likely to develop severe symptoms and suffer from complications. The findings also explain why infants and toddlers are at elevated risk for flu-related issues.
The Supreme Court's decision will likely affect standard of medical care and practice beyond Ontario, with potential resource implications for the province. The ruling also raises concerns about the role of the Consent and Capacity Board in end-of-life decision-making.
A new study found that political values significantly influence public response to health disparities messages, with liberals and conservatives differing in their reactions. The researchers suggest that advocacy strategies need to be tailored to the audience's composition and goals.
A recent study found that exposure to Manga comics promoting fruit intake significantly improved healthy snack selection among minority students. The intervention resulted in a 26% increase in children choosing healthy snacks compared to those without the comic exposure.
A new study from Rice University and the University of North Texas suggests that physical similarity is not the dominant rule in human mating when it comes to height preferences. Women prefer taller partners mostly for protection and femininity, while men prefer shorter women but not extremely short ones for intimacy purposes.
New research suggests that playing as a heroic or villainous avatar in video games can impact participants' behavior towards anonymous strangers. For example, those who played as Superman poured more chocolate than chili sauce, while those who played as Voldemort poured more chili sauce than chocolate.
Researchers at Queen Mary University of London have discovered a 'cell hijack' method in pancreatic cancer where pancreatic stellate cells are recruited to aid the growth and spread of cancer. This process can be blocked to prevent tumour growth, suggesting new therapeutic strategies for treating pancreatic cancer.
Researchers found that peaceful cooperation triggers the alignment of social categories with coalitional alliances, regardless of race. The study's findings suggest that cognitive systems are specialized for detecting alliances in the social world, but do not necessarily link racial differences to patterns of cooperation and conflict.
Researchers warn that soccer's unique aspect – the purposeful use of the head to control the ball – may contribute to long-term cognitive consequences. Studies found concussions accounted for 5.8% to 8.6% of injuries in soccer games, with players who executed more headers experiencing memory and planning deficits.
A Kaiser Permanente study found that an EHR-based screening program for abdominal aortic aneurysms (AAAs) reduced the number of unscreened at-risk men by over 50% in 15 months. The program used electronic health records to signal providers that patients needed screening, leading to a significant decrease in unscreened patients.
Researchers successfully controlled nanomotors inside live human cells, powered by ultrasonic waves and steered magnetically. The ability to manipulate cells from the inside holds promise for treating diseases such as cancer.
Researchers found that hydrogen sulfide regulates the body's production of nitric oxide, which protects the heart muscle against cell death. The study's discovery has far-reaching implications for developing novel treatments for cardiovascular disease.
A recent study published in Cancer journal found that smoking is significantly linked with an increased risk of estrogen receptor positive breast cancer among young women. Young women who have smoked a pack a day for 10 years or more experience a 60% higher risk of developing this type of breast cancer.
Using point-of-care ultrasound for suspected appendicitis in kids has been shown to reduce emergency room length of stay by 46% and avoid unnecessary CT scans. The study found no cases of appendicitis were missed, and surgeons became more comfortable using ultrasound for decision-making.
Researchers have identified twenty specific proteins secreted by primary effusion lymphoma cell lines, which may explain the cancer's peculiar behavior. These proteins are involved in inflammation, immune response, and cell growth, and their presence in tumor cells could lead to more personalized treatment approaches.
Research on drifting herbicides reveals mixed effects, including positive, neutral, and negative impacts on neighboring fields and farms. Grasses dominated field edge test sites, while herbicide drift was associated with declines in three species of herbivores.
Scientists at UNC Chapel Hill have identified a nonflammable alternative to the inherently flammable electrolyte used in current lithium-ion batteries, paving the way for safer and more efficient electric vehicles. The new material, PFPE, exhibits unique properties that make it an ideal replacement, with potential applications in aeros...
Researchers found a 400% increase in obesity and 250% increase in diabetes among TV, computer, and car owners in low-income countries. The study suggests that these modern conveniences contribute to a sedentary lifestyle, leading to increased rates of obesity and diabetes.
Researchers have developed a new live-cell printing technology called BloC-Printing that can print living cells onto any surface in a grid-like formation. The technology, which manipulates microfluidic physics to guide cells into hook-like traps, produces high survival rates of over 100% compared to traditional inkjet printing.
A study published in The Journal of Immunology found that Interleukin 21 (IL-21) contributes to fatal inflammatory disease, particularly when another cytokine is deficient. Removing IL-21 can greatly subdue the inflammatory response and may help people with chronic inflammation due to defective T cell regulation.
Scientists at the University of York have developed hemp plants with dramatically increased oleic acid content, making them attractive for cooking oil production. The new oil profile has a longer shelf life and greater heat tolerance, opening up industrial applications.
Research finds polar bears have unique genetic variations that influence nitric oxide production, a key factor in energy metabolism and thermogenesis. This adaptation enables them to survive the harsh Arctic environment without hibernation.
A team of researchers at Columbia University has developed a CMOS chip that can electrochemically image signaling molecules from bacterial colonies, providing new insights into how biofilms form. The chip enables direct detection of small molecules, such as phenazines, which control gene expression and contribute to colony morphogenesis.
Daniel W. Armstrong, a professor at UT Arlington, will receive the ACS Award in Separations Science and Technology for his development of novel applications with major impacts in the field of separation science and technology. He has also made significant contributions to chromatography, including the development of over 30 different t...
Researchers suggest lower-intensity statin combination therapy as an alternative to high-intensity monotherapy for certain patients. Meanwhile, a medical author argues that personal genome services lack evidence to support their claims and may overwhelm the healthcare system.
Researchers at Cedars-Sinai will investigate the potential links between air pollution and brain cancer, with a focus on three pollutants: naphthalene, butadiene, and isoprene. The study aims to determine if prolonged exposure to these toxins can cause molecular changes in the brain that lead to brain tumor development.
The FASEB MARC Program has announced seven travel awards totaling $12,950 to support students and scientists from underrepresented groups at the Association of Biomolecular Resource Facilities (ABRF) 2014 annual meeting. The program aims to increase diversity in biomedical research.
A new study published in the Journal of Bone and Joint Surgery found that obese children are at a higher risk of developing complex elbow fractures and experiencing postoperative complications. The study, which included over 350 patients aged 2-11, highlights the importance of early exercise and bone strengthening to prevent such issues.
The IMPaCT model, which employs trained lay Community Health Workers (CHWs), has been shown to improve patient experiences and health outcomes. The intervention group had a 52% greater chance of seeing a primary care physician within two weeks after discharge and reported better communication with healthcare providers.
A study found that patients undergoing PCI have a higher risk of dying from non-cardiac diseases than heart disease, with only 37% of deaths being cardiac-related. The researchers attribute this to improved cardiac therapies, such as medication and catheterization laboratory technologies.
Researchers find Pacific trade winds have driven more heat into oceans, slowing global warming; however, when winds weaken, heat will rapidly return to atmosphere. The study suggests a hiatus in global warming is temporary and temperatures will soon rise rapidly.
Researchers found that fallow bucks respond differently to fast vs. slow rate groans, indicating they signal aggression through calling speed. Bucks also recognize early-rut groans as more threatening than late-rut ones, helping them avoid exhausted rivals during mating season.
Researchers have discovered a new, red-light-sensitive opsin called Chrimson that enables the independent control of two brain populations. The new opsin was found in a screen of algae and can mediate neural activity in response to red light with high precision.
The discovery of the oldest known star in the Universe allows scientists to study its chemistry, providing a clearer idea of the early universe. The ancient star is around 6,000 light years from Earth and formed shortly after the Big Bang.
A study of over 48,000 patients and 139,000 healthy controls from four ethnic groups revealed seven new genetic regions associated with type 2 diabetes. The research provides insights into the biological processes involved in the disease and may lead to novel therapies.
A study involving twin sisters has identified a novel molecular target, SETD2, which can become a way to treat recurring and deadly malignancies. The researchers found that the SETD2 gene mutation contributes to the initiation and progression of leukemia by promoting the self-renewal potential of leukemia stem cells.
Researchers at MIT have developed a new, low-power signal-processing chip that could lead to a wirelessly rechargeable cochlear implant without external hardware. The device uses the natural microphone of the middle ear and can be charged via an ordinary cell phone in two minutes.
Researchers have found a way to efficiently edit the human genome one letter at a time, boosting ability to model human disease and paving the way for therapies that fix genetic 'bugs'. The new technique highlights out-of-the-box thinking critical for scientific success.
The study provides critical information for targeting conservation efforts and highlights the need for urgent action to protect biodiversity. Climate change is expected to force plants and animals to adapt or migrate to track their ideal climate, with some species facing significant challenges in finding new habitats.
Researchers at Scripps Research Institute create Inforna, a technique to identify potent compounds targeting cancer-causing microRNAs. The method enables unprecedented targeting of disease-associated RNAs, offering a promising approach to designing novel anti-cancer drugs.
A study published in Neuron has identified a small protein, Endothelin-1, that can be targeted to promote repair of damaged brain tissue in multiple sclerosis patients. The molecule inhibits myelin repair, and blocking it or using genetic approaches may help restore myelin in the brain.
The TRMM satellite measured intense feeder bands producing the heaviest rain near La Reunion and Mauritius Islands, dropping 175mm/hour at a rate of over 6.9 inches.
A genetic variation near an area that encodes for interferon-lamda3 (IFNL3) is responsible for the differences between those who can and cannot effectively clear HCV. Individuals with a favorable IFNL3 genotype have a better outcome in fighting HCV.
Researchers at Aarhus University have developed tiny, degradable 'medicine factories' inside the body that can produce specific medicines in response to specific enzymes. The technology, funded by a €2 million ERC grant, has the potential to revolutionize pain relief and cancer treatment.
The UCLA research team aims to restore patients' independence by returning their ability to type on a keyboard, open doors and transfer themselves between their bed and wheelchair. The most promising therapy uses electrical impulses to stimulate dormant pathways within the spinal cord.