A study by Yale University researchers found that Medicare spending on breast cancer screening increased significantly between 2001 and 2009, despite no corresponding decrease in new breast cancer cases. The use of digital mammography technology, which is more expensive than standard film technology, contributed to the increase.
A study published in JAMA found that whole-exome sequencing successfully identified the underlying gene mutations causing mitochondrial respiratory chain defects, leading to a 60% diagnostic yield. This approach outperformed traditional methods, detecting new potential disease genes and improving the diagnosis of neurometabolic disorders.
A new study by the London School of Hygiene and Tropical Medicine and UNAIDS found that scaling up HIV services can achieve substantially lower unit-costs per patient. Integrating these services with other healthcare services, such as tuberculosis treatment, can lead to better value for money.
Researchers identified a new biomarker that predicts glioblastoma response to chemotherapy temozolomide, improving patient outcomes. The biomarker targets MGMT-regulating microRNAs, which suppress the cancer-killing effect of temozolomide.
Half of US adults suffer from at least one chronic condition, with a quarter having two or more. The report highlights the need for coordinated action to reduce the chronic disease burden, including promoting health and healthy behaviors, effective prevention services, and stronger links between healthcare and community services.
Researchers at IMIM have identified galectin-1 as a potential therapeutic target for pancreatic cancer, demonstrating improved survival rates of 20% in mice. The inhibition of this protein mainly affects the immune system and surrounding tumor cells, suggesting a new strategy for treating pancreatic cancer with minimal side effects.
A new study found that simpler marine organisms, like bacteria and unicellular algae, can withstand higher temperatures than complex ones, such as animals and plants. The researchers discovered that the complexity of an organism's structure determines its ability to adapt to warmer waters.
The modENCODE Project has provided new genomic advances on embryonic development, DNA replication, and transcriptional regulation. Researchers compared developmental gene expression between Drosophila melanogaster and Caenorhabditis elegans, finding conserved gene expression patterns during development, despite significant differences ...
According to the report, nearly 180,000 people die each year from preventable causes such as automobile crashes and drug overdoses. Preventive strategies show promise in reducing these deaths, particularly child safety seats, seatbelt laws, and drink driving laws.