The Journal supplement highlights innovative approaches to healthy aging, including community-based efforts, technology uses, and civic service. Strategies like Experience Corps and volunteering are shown to enhance social engagement, independence, and well-being in older adults.
A recent study suggests that emissions from human activity have caused a decline in monsoon rainfall over the past 50 years. The research, published in Geophysical Research Letters, found that rising levels of anthropogenic aerosols are responsible for the decrease, which affects billions of people primarily in India and parts of Africa.
University of Minnesota researchers have identified microRNAs miR-182 and miR-503 that contribute to the development of colon polyps into cancerous tumors. By targeting these microRNAs, physicians may be able to provide earlier and more specialized treatment for patients with a higher risk of colon cancer.
A new genetic test developed by scientists can detect canine fecal contamination in water, providing insights into the scale of the problem. The test identified 11 genetic markers common to most dog samples but absent from human ones, revealing the significant role dogs play in contaminating US waterways.
Sick mice produce specialized sugars to feed their gut microbiota and resist infection. Healthy recovery requires both L-fucose production and intact gut microbiota. The study suggests a potential role for L-fucose in preventing or tolerating Crohn's disease.
Researchers conducted life history interviews with 26 health workers who lived through conflict in Northern Uganda, revealing their resilience and coping mechanisms. The study proposes solutions to protect and motivate health workers during and after crises, including community support, formal promotion, and regular pay.
A genetic study suggests that individuals with a specific genotype may be prone to weight gain and increased risk of diabetes and heart disease when exposed to chronic stress. Simple interventions like healthy diet, exercise, and stress management could help reduce the risk of cardiovascular disease in these individuals.
Researchers have successfully treated a genetic form of intellectual disability in mice using an anticancer drug, suggesting a potential new approach for the human condition. The study's findings indicate that altering the balance between chromatin's open and closed states could be key to treating Mendelian disorders of the epigenetic ...
A new study found that providing free contraception and education on various methods significantly reduced teen pregnancies, births, and abortions. Among participants, 72% opted for long-acting forms like IUDs or implants, leading to a 34-per-1,000 pregnancy rate among teens compared to 158.5 in 2008.
New research suggests that long non-coding RNAs play a crucial role in regulating the human immune system's response to infection. The study reveals how these molecules can promote, fine-tune, and restrain the body's inflammatory response by controlling gene expression.
Scientists at Cincinnati Children's Hospital Medical Center developed a new cell transplantation therapy to treat mice with a rare lung disease. The therapy, using macrophages, corrected the disease in mice and showed promise for treating other human lung diseases caused by dysfunctional immune cells.
An international study found that introducing gluten at different ages has no effect on developing celiac disease, and genetic factors are the primary risk factor. The study's results suggest a blood test for HLA genotype could determine high-risk infants, paving the way for preventive interventions.
Researchers have identified a novel source of stem cells in the corneal limbus that can be directed to behave like photoreceptor cells, potentially treating conditions like age-related macular degeneration. These cells can also be cultured from older eyes and may offer a promising approach for new treatments.
New research published in the BMJ suggests that long-acting insulin is superior to intermediate-acting insulin for controlling blood sugar levels, preventing weight gain, and treating severe hypoglycemia. Long-acting insulin also showed improved cost-effectiveness compared to intermediate-acting insulin.
A study published in Science Signaling found that JAK inhibitors can effectively treat over 80% of bowel cancers with a genetic mutation present in more than 80% of cases. The researchers discovered that these inhibitors block tumour growth by targeting the Wnt signaling pathway, with minimal impact on normal cells.
Researchers have identified a molecular mechanism that could explain why the common cold can bring on life-threatening asthma attacks. A small molecule called IL-25 may play a central role in triggering these attacks, and blocking it could potentially produce a much greater therapeutic effect.
The National Science Foundation is investing $31 million in 17 innovative projects to develop tools, cyberinfrastructure, and best practices for data science. These projects aim to create a robust national data infrastructure that supports research priorities and emerging data policies.
A new study from the University of Melbourne found that acupuncture did not improve chronic knee pain in patients older than 50. The research, published in JAMA, involved 282 participants who received either real or sham acupuncture for 12 weeks.
Researchers found that Montmorency tart cherry juice lowered blood uric acid levels and increased specific anthocyanin compounds, which may help alleviate joint pain and inflammation associated with conditions like gout. The study also detected increased C-reactive protein in the bloodstream after consuming tart cherries.
Fish larvae produce distinct 'knock' and 'growl' sounds within the hearing range of adult fish to maintain group cohesion during their pelagic journey. The sounds were observed in 70% of nighttime trials, suggesting a mechanism for larval communication.
A team of researchers will study the complex connections between brain cells that allow us to make and retrieve lasting memories. The project aims to build a complete computational model of a neural network in vertebrates using experimental data, with potential transformative insights into mammalian brain abilities.
Scientists at The University of Nottingham have made a major medical discovery that could lead to the development of an entirely new type of painkiller for chronic pain conditions like traumatic nerve injury. They found that a signal protein called VEGF promotes pain while its inhibiting form prevents it.
A study of Medicare data found that hospitals with high care intensity had lower failure-to-rescue rates after major surgery, but longer hospital stays. However, patients treated at these hospitals also experienced higher inpatient deaths and reduced hospice use.
Researchers propose a new method for measuring magnetic properties of materials at atomic resolution, utilizing the phase symmetry of an electron beam. This technique enhances the magnetic signal, enabling the detection of magnetism with unprecedented precision.