Researchers discovered a mutated regulator that disrupts blood cell production, leading to leukemia. Removing this regulator restored normal function and offers hope for new treatments.
Researchers are using multiparental populations to map complex trait genes in organisms such as mice, fruit flies, and maize. This approach enables the identification of specific gene regions associated with traits like nicotine resistance and toxicity of chemotherapy drugs.
Research from the University of Sydney measures positive and negative emotional states in dogs objectively, revealing that while most dogs are optimistic, some display pessimistic tendencies. Pessimistic dogs tend to be more stressed by failures and less willing to take risks.
A QUT study found that drivers underestimate speed limits at inactive roadwork sites, leading to high crash rates. The researchers suggest combining measures such as variable speed limit signs and police enforcement to improve safety.
A recent study published in the Journal of the National Cancer Institute has established a link between longer telomeres and increased melanoma risk. The research team identified seven genetic variations associated with telomere length and found that those with the longest telomeres are at a 30% increased risk of developing melanoma.
The Hastings Center and the Presidential Commission for the Study of Bioethical Issues have published a series of essays on bioethics education, highlighting gaps in knowledge and best practices. The papers focus on clinical ethics training for nurses, doctors, and medical students, emphasizing the importance of moral agency, reproduct...
The University of Texas at Arlington has received a National Science Foundation grant to boost its research capabilities, particularly in high-energy physics and data-intensive science projects. The grant will increase the campus's network performance to support researchers working on large-scale data analysis.
A new study shows that patients with HPV-positive oropharyngeal cancer respond better to treatment, making lingering neck bumps likely benign. This suggests skipping neck surgery for these patients could be a viable option.
Researchers have sequenced an ancient Iberian pig genome from the 16th century, finding it closely related to today's Iberian pig breed. The study suggests no significant changes in the genome over the past five centuries.
Hurricane Edouard's maximum sustained winds near 90 mph, with life-threatening rip current conditions expected along the US East Coast. The storm is forecast to rapidly weaken on Sept. 18, dropping in intensity to a tropical storm.
Researchers found a tiny galaxy, M60-UCD1, hosting a supermassive black hole with a mass of 21 million suns. The discovery suggests many ultracompact dwarf galaxies may contain huge black holes. The team used Gemini North and Hubble Space Telescope observations to estimate the black hole's mass.
The Interface Region Imaging Spectrograph (IRIS) mission has captured a unique perspective on an X-class solar flare, highlighting the transition region and corona. The observations provide insight into the dynamics of these powerful flares, which can have significant effects on Earth's magnetic field and radiation environment.
Astronomers using Hubble have found the smallest known galaxy with a supermassive black hole at its center. The galaxy, M60-UCD1, has a diameter of just 300 light-years and contains 140 million stars, yet it harbors a massive black hole weighing five times that of the Milky Way's central black hole.
Researchers found that leaders who prioritize others' perspectives produce better outcomes, especially when combined with power. Effective leadership involves balancing acceleration and steering to achieve successful results.
A study published in PLOS ONE suggests climate change may increase agricultural land availability in the North, but reduce it in tropical regions. This shift could lead to more frequent harvests in some areas and fewer in others, impacting global food production.
A new technique for detecting meat adulteration has been reported by scientists from Germany, offering a vast improvement over current methods. The approach uses protein analysis to reliably detect as little as 0.24% horse or pork in processed beef samples.
Researchers have developed a magnetic resonance technique to detect and quantify fat in the liver, improving upon traditional hepatic biopsy methods. The study uses magnetic resonance imaging (MRI) to measure liver fat content with high accuracy, providing valuable insights for diagnosing and monitoring liver diseases.
A team of researchers at Michigan Technological University has published an open-source library of syringe pump designs, making it cheaper for scientists to access this essential laboratory equipment. The designs can be printed on a 3D printer using inexpensive plastic filament and are customizable for specific experimental needs.
The Earth's massive tectonic plates are driven by a self-sustaining process that has shaped the modern planet. Early continents triggered plate motion by placing major stress on surrounding plates, forcing them to be pushed under at their edges.
Researchers found that artificial sweeteners can induce glucose intolerance by changing the composition and function of the gut microbiota. The study used mice and human data to show that certain bacteria in the gut react to artificial sweeteners, leading to inflammation and metabolic changes.
A QUT road safety expert has found that car security systems are virtually non-existent, leaving vehicles vulnerable to hacking. The risk of cyber attack increases as vehicles become more connected and autonomous.
ApoE3 helps repair blood vessels, while apoE4 prevents this process, leading to increased cardiovascular disease risk. Researchers discovered a potential preventive treatment using NO donors for individuals with the apoE4 variant.
A new study suggests that an autoimmune response may contribute to the development of high blood pressure. Using mouse models, researchers found that compounds stimulating hypertension led to the faulty production of modified proteins in dendritic cells, triggering an immune response.
A study published in the Journal of Computer-Mediated Communication found that habitual Facebook users are more likely to accept strangers as friends and give them personal information. This is because Facebook's design fosters habit formation and users with large social networks, frequent use, and impulsive behavior are more susceptib...
A team of researchers, led by Tom Broadhurst, has reinterpreted cold dark matter as a Bose-Einstein condensate, proposing that it governs the formation of the universe's structure. The theory predicts galaxies formed relatively late and could explain puzzling cores in dwarf galaxies.
Researchers found a 72% and 78% increase in childhood asthma risk among children exposed to butylbenzyl phthalate (BBzP) and di-n-butyl phthalate (DnBP), respectively, during pregnancy. Prenatal exposure to these phthalates can lead to inflammation and oxidative stress, increasing the risk of asthma.
A study from Oregon State University psychology professor Kathleen Bogart found that people with facial paralysis are perceived as less happy and sad because they can't communicate through facial expressions. The research highlights the importance of facial movement in everyday communication.
A new study finds that people with middle-age migraines are more likely to develop Parkinson's disease and other movement disorders. Those with migraine with aura face a higher risk, with women also being more prone to a family history of the condition.
A new MRI technique using Diffusion Tensor Imaging (DTI) can help clinicians predict the likelihood of poor clinical outcomes following mild traumatic brain injury. This technique shows significant differences in white matter between mTBI patients with positive versus negative findings on CT and MRI evaluation.
A new study by NYU Langone Medical Center identifies a specific neurobiological basis for key symptoms of post-traumatic stress disorder (PTSD), including sadness, emotional detachment, and listlessness. The research uses brain imaging to link an opioid receptor in the brain to these symptoms, suggesting a potential target for personal...
The North American Menopause Society (NAMS) has published its first comprehensive set of evidence-based recommendations for the care of midlife women. The guide covers over 50 key topics, including vasomotor symptoms and osteoporosis, providing practical advice for clinicians and patients.
According to a study by the University of the Basque Country, the mobility model is closely linked to the city's characteristics. The study found that compact towns and cities have lower private vehicle use, better public transport offers lead to less car usage, and higher per capita income is associated with greater private car use. T...
A new treatment regimen has been found to be safe and effective in restoring skin pigmentation in vitiligo patients. The study, led by Henry Ford Hospital, showed that a combination of afamelanotide and phototherapy using narrowband ultraviolet-B rays resulted in faster repigmentation compared to UVB treatment alone.
Researchers developed a math model that can predict the progression from nephritis to interstitial fibrosis in lupus patients. The model can also gauge the effectiveness of experimental treatments for inflammation and fibrosis, reducing the need for invasive biopsies.
A Yale study found that patients with early-stage non-small cell lung cancer who underwent conventional surgery had better long-term outcomes than those treated with radiosurgery. The study used Medicare billing records of 1,078 patients and found a significant difference in complications and mortality rates between the two groups.
Women with PTSD experienced higher rates of food addiction due to earlier symptom onset and more severe trauma experiences, suggesting a potential link between PTSD and obesity-related issues.
Researchers at Karolinska Institutet found that age-dependent reduction of mitochondrial function in beta cells leads to reduced insulin release. Impaired calcium ion dynamics is the molecular mechanism underlying this process.
New research from the Copenhagen Centre for Social Evolution and Yale University found a strong link between birth weight and risk of developing mental health disorders such as autism and schizophrenia in adolescence. The study, which analyzed medical records of 1.75 million Danish births, found that smaller babies were at higher risk ...
Researchers developed tiny hollow shells to contain Li-S compounds, achieving high-energy storage capacity of 630 mAh/g. The new battery technology could potentially offer up to five times the energy of existing lithium-ion batteries.
Researchers have discovered new complex oxides that exhibit both magnetic and ferroelectric properties, combining characteristics of logic circuits and spintronics. The findings, published in Scientific Reports, bring scientists closer to creating ultra-efficient memory devices with massive storage capacities.
Researchers studied how average people with high blood pressure, heart disease, diabetes, and other common conditions performed during simulated flight. They found that nearly everyone tolerated the stresses of commercial spaceflight without problems.
Researchers at Moffitt Cancer Center have discovered 23 new regions of the genome linked to prostate cancer risk, with testing potentially identifying men with a six times higher risk. This brings the total number of genetic variants linked to prostate cancer to 100.
The Great Barrier Reef is an effective wave absorber, driving currents that transport nutrients and larvae. Wave reduction also has implications for shoreline stability. The reef's porosity varies by location, influencing wave height reduction.
Researchers have found a supermassive black hole at the center of an ultra-compact galaxy, M60-UCD1, with a mass of 21 million suns. This discovery suggests that these massive black holes are more common in less-massive galaxies than previously thought.
Astronomers used Hubble and ground observations to find the M60-UCD1 dwarf galaxy containing a massive black hole. The discovery suggests compact galaxies may be remnants of larger galaxies torn apart during collisions.
Regular physical activity and avoiding sedentary lifestyle crucial for brain health in older age. Older adults who engage in moderate-to-vigorous exercise tend to have less white-matter lesions, a key indicator of cognitive decline.
A major new study shows that some prostate cancer treatments can stop working over time and even drive tumour growth. Researchers identified a 'treatment paradigm' using repeated blood samples to monitor signs of therapy becoming counter-productive.
A UT Arlington engineering professor and his doctoral student have designed a device based on a shorebird's beak that can accumulate water collected from fog and dew. The device could provide water in drought-stricken areas of the world or deserts around the globe, offering an alternative to current methods.
Researchers found that toddlers' abilities to accurately guess word meanings increase with age, while social cues become less effective. Children can retain around three new words per day, highlighting the importance of rich word-learning environments.
The European Menopause and Andropause Society (EMAS) has published a position statement on breast cancer screening, recommending individualized screening based on familial risk and first screening mammogram results. This approach aims to reduce overdiagnosis and unnecessary treatments for slowly growing tumors.
A new survey by the Media Insight Project finds that African Americans and Hispanics are using digital technology at similar rates as the US population, but face a lack of diverse content in their communities. Despite this, many believe their communities are under-represented in the media.
Researchers studied astronauts' movements in low gravity and found that they could maintain higher speeds while walking on the moon. The team used NASA's DC-9 aircraft to simulate lunar gravity and tested the speed at which walkers transitioned from a walk to a run, discovering an average speed of 1.4m/s, exceeding previous estimates.
The project will support a series of events exploring human self-definition and the concept of humanism in the face of scientific advancements. The initiative aims to build bridges between arts, humanities, and sciences at Penn State.
Researchers identify how bacteria prioritize instructions and create a 'shredder' enzyme that destroys old messages. By targeting this enzyme with antibiotics, deadly bacterial infections may be killed, providing new hope for treating human illnesses.
Researchers found that combining targeted radiation therapy (SBRT) with the drug cetuximab improved treatment outcomes for patients with recurrent squamous cell carcinoma of the head and neck. The study showed a significant reduction in severe toxicity, allowing patients to complete treatments faster.
A new research study will analyze how changes in diet and lifestyle affect long-term wellness and contribute to healthy aging. The Stanford Prevention Research Center will lead the study, which aims to identify lifestyle and environmental factors that help people maintain their health and wellness as they age.
Researchers found that chokeberry extract killed off cancer cells and boosted the effectiveness of chemotherapy drug gemcitabine in treating pancreatic cancer. The extract's anti-cancer properties were tested on human pancreatic cancer cells, with results suggesting a potential synergy between the two.
Researchers are studying nature's secrets to develop efficient light-based technologies. From seashells to spider wings, scientists are discovering inspiration in the natural world to create innovative solutions for energy, healthcare, and communications.
Despite Congress's adjournment, the Sustainable Growth Rate (SGR) Repeal and Medicare Provider Payment Modernization Act of 2014 remains a crucial issue in healthcare finance. Experts, including Dr. Eli Adashi, advocate for bipartisan efforts to address the SGR law and promote reforms to move Medicare towards quality-based compensation.
Michigan State University scientists have discovered the first detailed examination of mutations similar to those present in the human cancer gene. The study reveals that boosting levels of even standard protein can alter fruit flies' eyes and wings, while mutated protein causes consistent and dramatic deformations.