Scientists have discovered that a single genetic change in the Bmp6 gene is associated with an increase in tooth number in freshwater sticklebacks, which can lead to cleft palate deformities. The study suggests that regulating this gene may hold the key to replacing human teeth and improving tooth formation.
Researchers analyzed data from over 17,000 surveys to track changes in urinary and sexual symptoms following various prostate cancer treatments. The study found that certain treatments, such as surgery and low-dose rate brachytherapy (LDR), may cause temporary increases in symptoms, while others, like intensity modulated radiation ther...
The prevalence of abdominal obesity and average waist circumference increased significantly among US adults between 1999-2012. The overall age-adjusted average waist circumference rose by 1.2 inches in men and 1.5 inches in women, with significant increases seen across different racial groups.
The article emphasizes the need for improved access to female-controlled contraceptive methods to counteract reproductive health risks caused by intimate partner violence. Clinicians can help women and girls regain control over their reproductive health through availability of effective contraceptives.
Scientists at Boston University and Stanford University School of Medicine attach E. coli colonies to a microcantilever, allowing real-time monitoring of bacterial motion and communication patterns. The new system enables rapid assessment of antibiotic susceptibility and potential applications in cancer drug development.
A randomized trial found that IVUS-guidance significantly improved 12-month clinical outcomes after new-generation drug-eluting stent implantation, compared to conventional angiography-guided CTO intervention. The IVUS-CTO study showed lower rates of cardiac death, myocardial infarction, and target-vessel revascularization in the IVUS-...
Researchers have discovered a way to control the properties of quantum dots by using ultrathin layers of metal oxides. This new approach makes quantum dots glow brighter and enhances their emission efficiency, which is crucial for applications such as sensors, light-emitting diodes, and solar cells.
Researchers at the University of Warwick found that a mathematical model replicating Ebola outbreaks can no longer predict its scale. The current outbreak is 'out of all proportion' and defies previous patterns.
A meta-analysis of 757 Stage IV NSCLC patients found that factors such as timing of metastases and lymph node involvement impact overall survival. The study identified three risk groups with different five-year OS rates, and highlighted the importance of identifying patients who are most likely to benefit from aggressive treatments.
A new study suggests that artworks are perceived as an extension of the creator, with original pieces valued more highly than copies. The researchers propose a concept called 'magical contagion,' where the artist's physical presence imbues the work with their essence.
A phase I/II trial of hypofractionated radiation therapy found that prostate cancer patients reported similar quality of life, bladder and bowel function before and after treatment. The study's results also indicated that different regimens of hypofractionated RT produced similar outcomes in terms of patient-reported quality of life.
A urine HPV test showed high accuracy in detecting the virus compared to traditional cervical sampling methods. The test had a sensitivity of 87% and specificity of 94%, with improved results when using first-void urine samples.
A global study of 80,000 men with prostate cancer has identified another 23 prostate cancer risk loci, bringing the total to 100 genetic regions associated with the disease. The study found that these genetic variants explain 33% of familial risk and can be used to predict aggressive form of prostate cancer.
A study of 307 patients with treatment-resistant MDD found that NeuroStar TMS Therapy induced significant response and remission, which were maintained through 52 weeks. At one year, 68% achieved symptomatic improvement and 45% reported complete remission.
Researchers from UCI capture moving images of a single molecule as it vibrates and shifts between quantum states, opening a window into the realm of quantum mechanics. This breakthrough could lead to applications such as lightning-fast quantum computers and uncrackable encryption.
Researchers found that radiation oncologists are using fewer or less-aggressive radiation procedures on elderly women with early-stage breast cancer. The study confirms that radiation oncologists are successfully balancing patients' needs with the cost of providing healthcare.
The HS3 mission gathered data on Hurricane Cristobal as it became an extra-tropical storm, revealing strong winds and dry air moving eastward across the western side of the storm. The data showed a shift in the strongest winds outward from the center compared to earlier stages in the storm's lifecycle.
Researchers studied lamprey embryology to understand the evolutionary origins of modern vertebrates. They discovered that Hox genes play a crucial role in hindbrain segmentation, which is conserved across vertebrates.
Approval of Keystone XL would increase oil sands extraction, leading to higher greenhouse gas emissions, according to a survey of experts. The study suggests that KXL could raise CO2 emissions by 1-40 million metric tons per year, depending on market responses.
Research found that NSCLC patients who never smoked had a significantly lower risk of developing secondary primary lung cancers (SPLC) compared to current smokers. The study analyzed 1,484 patients and found that five years after diagnosis, current smokers were more likely to develop SPLC.
A study of 91 prostate cancer patients found that vessel-sparing radiation therapy preserves sexual function without compromising cure rates. Patients who received combination EBRT and brachytherapy reported improved sexual function at five years post-treatment.
Researchers have created a smart material-based chin strap that generates electricity from chewing, eating and talking, with potential to power hearing aids, cochlear implants and other small electronic devices. The device harnesses piezoelectric fiber composites to convert mechanical stress into electric charge.
Researchers at Columbia University and the University of Michigan found an interaction between the ADRB2 gene and childhood adversity in a study of Ohio National Guard soldiers. The study suggests that genetic variations can influence PTSD symptoms, particularly in individuals with two or more experiences of childhood trauma.
Research suggests that lactation may reduce the risk of estrogen receptor-negative and triple-negative breast cancers in African American women. Parous women had a higher chance of developing these aggressive subtypes if they never breastfed, particularly those with four or more births.
A recent study found that men who viewed images of sexy women felt less connected to others and were less likely to make charitable contributions. Exposure to such images temporarily decreased male consumers' sense of psychological connectedness with others, making them less receptive to ads promoting social benefits.
Researchers analyze 13 wearable activity monitors to determine their effectiveness in promoting healthy behaviors. While many apps are in line with health community recommendations, some lack key features such as action planning and problem-solving tools.
Researchers at USC have developed a technique to twist radio beams and transmit data at high speeds of 32 gigabits per second. This method outperforms traditional optical systems and could enable ultra-high-speed links for next-generation cellular systems.
A network meta-analysis of nearly 50 randomized trials compared the efficacy and safety outcomes of eight anticoagulation options for venous thromboembolism. Rivaroxaban and apixaban were associated with the lowest bleeding risk, while UFH-vitamin K antagonist combination was linked to higher recurrent venous thromboembolism rates.
Researchers at Hebrew University develop a new cocktail of genes to coax adult cells into pluripotent stem cells, producing high-quality results. The new approach improves upon existing methods by reducing genetic abnormalities and increasing the proportion of successful cell reprogramming.
A study in Journal of Consumer Research found that loyal consumers overestimate their chances of winning random prizes. Higher levels of loyalty affect how likely consumers think they are to receive random rewards.
Researchers propose epigenetic drugs to treat cancer resistance and relapse by modifying gene expression. Studies suggest epigenetic changes contribute to cancer progenitor cell formation, drug resistance, and relapse.
Female northern swordtail fish are attracted to specific patterns visible in polarized light, increasing mating chances for males with higher polarization. The camera developed by Viktor Gruev captures real-time polarization properties of light, revealing new insights into vertebrate behavior.
A new randomized trial demonstrated that optical coherence tomography (OCT) guidance during stent implantation in primary PCI for ST-elevation myocardial infarction (STEMI) improves patient outcomes. The OCT STEMI trial found lower area stenosis and fewer uncovered struts after nine months, indicating better long-term results.
Researchers have found that Topo 2, an essential enzyme for chromosome separation, needs more time to untangle long chromosomes, which can lead to mutations and cancer. The study suggests that chromosome length affects the enzyme's action and highlights the importance of understanding cell division.
A study by researchers from five universities found that contamination in drinking water wells in Pennsylvania and Texas stems from well-integrity problems such as poor casing and cementing. The analysis used noble gas and hydrocarbon tracers to identify the source of fugitive methane and determine if it is natural or not.
Researchers have identified a novel drug target, Kir7.1, that induces acute and sustained uterine contractions to treat postpartum haemorrhage (PPH), a major global cause of maternal mortality. The treatment bypasses biochemical pathways exhausted during prolonged labour, promising effective treatment at low doses.
The researchers emphasize the need for clear communication of science to policymakers and the general public to make informed decisions. They offer a communication protocol that involves identifying relevant facts, characterizing uncertainties, and assessing their magnitude.
Researchers found that the human version of the Foxp2 gene helps transform new experiences into routine procedures, enabling faster learning and better habit formation. The gene's protein, a transcription factor, regulates synaptic connections between neurons, allowing for more efficient learning and language acquisition.
Researchers uncover new insights into viral infections influencing SUP05 ecology and metabolic potential in oxygen-minimum zones. The study reveals viruses play a crucial role in marine microbial ecology below sunlit surface waters, with implications for ocean carbon cycling.
Scientists have discovered genes in zebrafish that may be synonymous with human airway genes, which could lead to new treatments for Primary Ciliary Dyskinesia (PCD) and other respiratory diseases. The study identified hundreds of novel genes associated with cilia formation, shedding light on the causes of defective motile cilia.
A new IEA study highlights the need for clear frame conditions to promote biomethane market growth. The report analyzes production technologies, grid injection, and use in various countries, emphasizing the importance of technical standards, sustainability requirements, and financial support.
The American Gastroenterological Association has released a new clinical decision tool to guide gastroenterologists in assessing and treating patients with Crohn's disease. The tool synthesizes current literature to create a practical algorithm for clinicians, providing a pathway for better quality care.
Researchers at Washington State University have found a key gene in wheat that can be used to transfer valuable traits from other plants, reducing crop losses and pesticide use. The discovery enables breeders to develop disease- and pest-resistant wheat varieties without the need for genetically modified organisms.
A study of nearly 4000 Taiwanese found that increased dairy consumption lowered cardiovascular mortality and stroke risks. Moderate dairy intake, even in lactose intolerant individuals, is beneficial for overall health.
A new study reveals that individuals with high intake of high-fat dairy products have a 23% lower risk of developing type 2 diabetes compared to those with low consumption. High fat from dairy may explain the protective association between dairy intake and T2D.
Researchers found pseudouridylation of mRNA in yeast and humans, increasing mRNA stability under heat shock conditions. This discovery has significant implications for understanding human diseases associated with PUS gene mutations.
A study of 57,256 individuals found that increased dairy consumption was associated with a lower incidence of hypertension. Milk intake was not linked to an increased risk of coronary heart disease or stroke. The findings support the potential health benefits of dairy products for cardiovascular health.
Researchers used brain scans to forecast early reading difficulties in kindergarteners, finding that white matter development predicts reading ability. The study suggests a new tool for clinicians to spot dyslexia and other reading challenges before they arise.
A new statistical model complements hurricane forecasting by showing the size of storms, not just wind speed. This metric allows forecasters to better assess the risk of hurricanes that make landfall.
Researchers at Moscow Institute of Physics and Technology have developed a new method for synthesizing ultrahard fullerite, a material with hardness values ranging from 150 to 300 GPa, surpassing diamond. The breakthrough synthesis requires lower pressures and can be achieved at room temperature, enabling industrial-scale production.
Adequate vitamin E levels are critical for fetal development and nervous system health. Inadequate intake is linked to increased infection, anemia, stunting of growth, and poor pregnancy outcomes.
Research found that socioeconomic status significantly affects childhood asthma outcomes, with poor consequences concentrated among economically disadvantaged children. Family environment and parental stress play a crucial role in managing asthma, highlighting the need for social and emotional supports.
Researchers question widely-held assumptions about hippo migration patterns, citing a lack of evidence for their ability to swim. Despite this, hippos have been found on several islands, sparking debate about the role of land bridges in their colonization.
Researchers suggest progesterone as a potential treatment for spinal cord injury due to its anti-inflammatory and neuroprotective properties. Studies demonstrate that progesterone preserves white matter integrity and improves locomotor function in animal models of spinal cord lesion.
A new study by the University of Michigan found that one in five men in the US report violence towards their spouses or partners, with warning signs including irritable bowel syndrome (IBS) and insomnia. The study suggests that male aggression can be identified through routine health care visits and could potentially be intervened upon.
Researchers found that magnetic stimulation of the dorsolateral prefrontal cortex (DLPFC) increases cravings for high-calorie snacks and consumption among healthy young women. Weakening DLPFC activity also reduces inhibitory control strength and increases reward sensitivity, making individuals more susceptible to overeating.
Patients with common variable immunodeficiency (CVID) experience recurrent bacterial infections due to exhausted T cells expressing inhibitory protein PD-1. Rejuvenating these cells through blocking PD-1 may offer protection against bacterial infections, suggesting a potential therapeutic strategy.
Researchers highlight patterns of institutional betrayal, including membership qualifications, power differentials, and institutional denial, which can lead to trauma and mistrust. They offer recommendations for reducing betrayal and suggest using the Institutional Betrayal Questionnaire to improve client-clinician discussions.
Researchers at Washington State University have identified specific genes in barley that enable the plant to live longer and become more tolerant of stress, including disease. These findings could lead to the development of crop breeding programs that slow aging and increase yields without genetic engineering.
New research provides estimates for probable maximum magnitude events in subduction zones for various time periods, including 250, 500 and 10,000 years. Most subduction zones can generate M 8.5 or greater over a 250-return period; M 8.8 or greater over 500 years; and M 9.0 or greater over 10,000 years.