Researchers used human embryonic stem cells to treat spinal cord injuries in mice, finding that the cells produced GABA, reduced neuropathic pain and bladder dysfunction, and improved voiding ability. The study suggests a new approach for treating chronic pain and bladder issues in spinal cord injury patients.
Researchers at Boston University School of Medicine have discovered a new role of the protein c-Cbl in degrading ?-catenin, a vital protein involved in cancer initiation. This finding could lead to new strategies to suppress Colorectal Cancer growth and improve patient survival.
A new study found that women who experience frequent nighttime hot flashes and sleep disruption are more likely to exhibit mild symptoms of depression. The researchers suggest menopausal women should be screened for mood disturbances, incorporating efforts to address sleep and nighttime hot flashes.
A study by Indiana University forecasts that vehicle mileage tax would generate more revenue than indexing gas taxes to inflation or applying sales taxes. Fuel tax revenue will decline by up to 50.5% between 2015 and 2040 if not adjusted for inflation.
University of Illinois researchers have developed a method to quantify drug delivery from nanoparticles inside a cell, providing new insights into the efficacy of therapy and mechanisms underlying cellular uptake. This breakthrough could lead to more effective treatments by controlling and manipulating drug release.
The NYU Holodeck is a well-integrated software/hardware instrument that combines visual, audio, and physical components to create an immersive research environment. It has the potential to create new insights into fundamental natural phenomena, offering unparalleled tools for intellectual and creative output across disciplines.
Researchers from the University of Kent's Durrell Institute of Conservation and Ecology found that trophy hunting is sustainable when companies are given long-term land management rights, thereby maintaining habitat for threatened lions. Sustainable land management helps to fill the shortfall of large areas needed by lions to thrive.
A recent study found that parents who reproduce later in life are more likely to have children with autism disorders, while older mothers are associated with reduced risks. In contrast, advanced paternal ages were linked to increased risks of most autistic disorders in offspring.
A team of scientists from NCAS and the Met Office observed an unusual reversal of the expected pattern in equatorial winds. The quasi-biennial oscillation is a regular feature of the climate system, but its recent disruption may impact seasonal forecasts and future climate predictions.
A study of 130 pregnant Sudanese women found a significant link between Rift Valley fever virus infection and miscarriage. The risk of miscarriage was seven times greater for infected women compared to those without the infection.
A study published by Nationwide Children's Hospital found that treadmill hand burns are the second most common hand injury after stovetop burns, requiring greater and longer care. Children under 5 years old are most prone to these injuries due to curiosity and lack of understanding about potential dangers.
A new study has associated genetic loci with bacterial species and metabolic signatures, revealing that human genes affect the microbiome. The study found associations between lactase variants and Bifidobacterium presence, as well as C-type lectin gene variants with immune system function.
Researchers found that gannets use shallow and short dives with less swimming when at ocean fronts, indicating abundant food closer to the surface. This study highlights the importance of these habitats for marine ecosystem functioning and could inform conservation efforts.
Researchers review how psychology helps people with diabetes manage their condition through behavioral intervention programs and identifying mental disorders associated with the disease. The article highlights the importance of psychological science in improving diabetes prevention and care.
A newly described species of extinct reptile from the Triassic period in Texas had a strikingly dome-shaped head, similar to that of dinosaurs. The study found internal partitions or zones in the skull, which were similar to those of pachycephalosaur dinosaurs.
A pair of experts, Mark Fendrick and Michael Chernew, propose altering consumer cost-sharing in health insurance plans to make services more affordable based on individual patient and provider factors. They suggest changes to IRS rules, Medicare plan design, and encouraging value-based cost-sharing to promote high-value clinical services.
Researchers found that a particular strain of HPV resulted in better overall survival for patients with oropharyngeal cancer. Patients infected with other strains had similar survival rates as those without HPV.
A review of published studies and FDA reports found that prescription sleep aids can stimulate patients instead of calming them, leading to a rare but serious risk of suicide. The main concern is the first few days after taking the medication, when a paradoxical response is most likely to arise.
Researchers develop genetically engineered peptides to transmit information between biological systems and synthetic materials, enabling a coherent bioelectronic interface. The discovery enables the creation of biomolecular solid-state devices with potential applications in biomedical and electro-optical devices.
A study by University of Plymouth found that washing clothes can release hundreds of thousands of tiny synthetic particles into the environment. The research suggests that laundry could be a significant source of microplastics in wastewater, with potential harmful effects on aquatic life.
A color-changing smart material sensor, developed by USC researchers, notifies users of their total UV exposure, allowing them to strike a balance between Vitamin D production and skin cancer prevention. The flexible patch, made from FDA-approved non-toxic polymers, works without a power source and can be stored for up to five weeks.
The Hikari supercomputer cluster uses solar panels for up to 208 kilowatts of power during the day, reducing the need for conventional AC power from the grid. This innovative system also employs high-voltage direct current (HVDC) technology, predicted to save 15% compared to traditional systems.
A major new study aims to uncover the secrets of ALS through research in Latin America, examining if mixed ancestry has a protective effect on developing the disease. The project will establish registers of incidence, prevalence, and risk factors for ALS in Cuba, Chile, and Uruguay.
A new study found an association between exposure to endocrine-disrupting chemicals (EDCs) and lower vitamin D levels in U.S. adults, with the link strongest in women. The study suggests that EDCs may alter the active form of vitamin D in the body.
A team of scientists has identified the African origin of the black grains grown by Suriname Maroons, tracing back to Mande-speaking farmers in Western Ivory Coast. The study combines ethnobotanic, historic and genetic research to uncover the migration history of people and crops.
Scientists developed a method to estimate weakness in the Earth's outer layers, allowing for more accurate predictions of volcanic activity and earthquakes. The new model uses surface-based electromagnetic imaging techniques to estimate viscosity variations, which can be used to understand processes driving tectonic plate deformation.
A new study mapping Japan's Sakurajima volcano's 'plumbing system' reveals a substantial growing magma reserve, threatening the safety of nearby residents. The team believes their pioneering techniques could help improve eruption forecasting and hazard assessment globally.
A new study from the University of Cambridge found that body-worn cameras are associated with a significant reduction in citizen complaints against police, with 93% fewer complaints filed after camera implementation. The 'observer effect' is believed to be a key factor, modifying behavior and increasing accountability.
Researchers from University of Eastern Finland discovered that retinal changes can be detected earlier than brain changes in CNS diseases. Functional abnormalities were found in three genetically engineered mouse models of human CNS diseases, suggesting eye examinations could be used as a noninvasive screening tool.
A group of pediatricians is urging the pediatric workforce to address opioid addiction among young people, highlighting the need for evidence-based treatment including medication-assisted treatment. Many young people continue to see their pediatric provider well into young adulthood, when they first struggle with opioid addiction.
Researchers have discovered a new earthquake hazard in the Afghanistan-Pakistan border region, revealing that the Ghazaband fault is accumulating more than half of the relative motion between tectonic plates. This increases the potential for a high-magnitude earthquake and poses a significant threat to cities like Quetta.
A recent study found that people can only correctly identify half of phishing emails, despite being cautious. Participants were more likely to be overconfident and fall for attacks if they perceived negative consequences.
Researchers found that midshipman fish rely on a light-driven internal clock and the hormone melatonin to determine when to sing. The study shows that melatonin acts directly on the vocal circuitry in the midshipman's brain, causing them to hum at night.
Researchers at Argonne National Laboratory have observed the deflection of magnetic skyrmions under an applied current, a phenomenon with potential applications in data storage and spintronics. The study's findings suggest that manipulating skyrmion motion could enable low-power data encoding and new device technologies.
Researchers from Queen Mary University of London have discovered the mechanism behind shape-shifting sea cucumbers' ability to rapidly change their stiffness. This unique property is controlled by a protein-rich interfibrillar matrix that can be altered by the nervous system, making it useful for developing novel biomaterials.
Multiple myeloma cells communicate with healthy bone marrow cells, altering protein translation initiation to create a favorable environment for cancer growth. This crosstalk allows tumor cells to modify the surrounding microenvironment, promoting progression and disease.
Researchers found that in cases of constant misreporting, the impact on fishery status is less critical than trend analysis, suggesting more sustainable management possible despite missing catch data. Misreporting can happen frequently worldwide, but many fisheries can still be well-managed with trends in population changes considered.
A Phase III randomized trial comparing intensity modulated radiation therapy (IMRT) to standard RT found that patients treated with IMRT had better bowel and bladder functions scores and required fewer anti-diarrheal medications. Quality of life measures also showed less decline for patients treated with IMRT.
A study published in Neurosurgical Focus reports the use of a minimally invasive laser procedure to treat large, 'inoperable' brain tumors, including glioblastomas. The procedure combines laser interstitial thermotherapy with a small craniotomy to remove cooked tumors and prevent swelling.
A new study by the University of Exeter and Plymouth Marine Laboratory reveals that coastal-dwelling marine wildlife are more vulnerable to harmful plastic pollution than previously thought. The research found that animals living in waters near densely-populated coastlines are at risk of coming into direct contact with microplastics.
Cephalosporins have shown promise in treating tuberculosis (TB) through an in vitro study, with the antibiotics demonstrating potent anti-mycobacterial properties when used in synergistic combinations with traditional therapies. The results suggest that these drugs could be part of new combinatorial TB therapies.
The Endocrine Society recommends continuous glucose monitors as the gold standard of care for adults with Type 1 diabetes, enabling better blood sugar control and reducing hypoglycemic events. The guideline also suggests using insulin pumps and emerging technologies like artificial pancreas devices to manage blood sugar levels.
A University of Arizona-led report reviews 125 reports on LGBTQ youth of color and highlights the lack of research on their normal developmental experiences. The study aims to fill this gap by emphasizing the importance of considering intersectionality between sexual orientation and race-ethnicity.
Researchers at Sylvester Comprehensive Cancer Center have identified a receptor that slows breast cancer metastasis when targeted. By blocking the receptor for advanced glycation end-products (RAGE), scientists decreased tumor growth, reduced angiogenesis and inflammation, resulting in lower metastatic rates to the lung and liver.
A substantial proportion of birth weight variation is attributed to genetic differences, with some 1/6th of the difference being due to genetics. The study also found a link between genetic differences in early growth and increased risk of adult diseases.
For the first time, researchers have identified rapidly proliferating cells in the corneal endothelium of specimens from normal corneas and those with Fuchs' Endothelial Corneal Dystrophy (FECD). This discovery holds promise for new therapies to be developed using these cells to return normal clearing abilities to patients with FECD.
Researchers have identified a rare mutation in the Non-Structural 1 protein that renders the flu virus defenseless against the immune system. This discovery could lead to the development of more effective live flu vaccines.
A new study using genetic markers has found that urban Puget Sound shorelines support a denser array of animals than in remote areas. The researchers detected over 1,600 unique genetic signatures, including species such as clams, salmon, and eagles.
Researchers have discovered a phenomenon where certain oxides oscillate when exposed to water vapor, generating oxygen gas and exhibiting flexibility unlike expected. The exact frequency of the oscillations can be precisely tuned, which could have practical applications in battery materials and water-splitting devices.
A new study suggests that drinking cold water can reduce feelings of shame and regret by regulating emotions and temperature. Researchers found that people in warm environments tend to feel more regret after making mistakes, but consuming cold drinks or being exposed to cold temperatures can help alleviate these emotions.
A researcher from Aalto University has created a controlled rogue wave in realistic oceanic conditions, shedding light on the phenomenon of extreme ocean waves. This breakthrough enables the design of safer ships and offshore rigs by simulating realistic rogue waves in laboratory environments.
A $248,083 grant supports UTSA professor Wassim Ghannoum's research on high-strength rebar, aiming to establish new concrete structure standards. The project could cut steel costs by a third and have positive environmental effects.
Researchers at University of Cincinnati find non-deleterious sulfate minerals in ancient soil and water, increasing fertility for maize cultivation. The discovery sheds new light on the Ancestral Puebloans' thriving agricultural urban center.
Researchers at Oak Ridge National Laboratory have discovered the key to piezoelectric excellence in relaxor-based ferroelectrics, enabling more detailed electrical signals and better images in medical ultrasound. The findings may provide knowledge needed to accelerate the design of functional materials for diverse applications.
Researchers developed a method to measure lithosphere strength using magnetotelluric imaging, revealing accurate descriptions of surface structures and correlating with volcanic and seismic activity. This technique may aid understanding of earthquake and volcanic processes.
Researchers have crystallized a protein that holds answers to how nicotine addiction occurs in the brain, opening up new possibilities for developing treatments. The breakthrough may also lead to medications for certain types of epilepsy, mental illness, and dementia.
A recent study published in The Lancet Public Health found a strong association between economic opportunity and measures of physical and mental health in young adults. Individuals living in areas with higher economic opportunity reported fewer days of poor health and adopted healthier behaviors.
Scientists discovered that a common intestinal microbe produces an enzyme called SagA, which protects worms and mammals from harmful bacteria like Salmonella typhimurium. The findings could lead to the development of probiotics against Clostridium difficile, a leading cause of hospital-acquired infections.
A study by Georgia State University researchers found that yoga can reduce worry, the main symptom of Generalized Anxiety Disorder. The findings suggest that yoga has promise in helping people with this condition reduce their symptoms and improve quality of life.
A recent expert review from the International Osteoporosis Foundation confirms that both type 1 and type 2 diabetes increase the risk of bone fragility. The mechanisms behind this include hyperglycemia, oxidative stress, and microvascular complications, which alter bone turnover and material properties.