The article explores the economic aspects of cancer care, highlighting the need to assess the value of healthcare innovation. It discusses the rising costs of new treatments and the potential impact on healthcare budgets. The Special Issue provides a review of health economics in cancer research and care.
The Alcator C-Mod tokamak achieved a record-breaking plasma pressure of 2.05 atmospheres, exceeding previous values by approximately 70 percent. This result validates the high-field approach to fusion energy, which could lead to smaller and cheaper fusion power plants.
Scientists have discovered 43 new species of scaffold web spiders, significantly increasing the known family size by approximately 20%. The discovery was made through a comprehensive survey of individuals collected from across China, Indonesia, and Southeast Asia.
Researchers develop a new therapy that prolongs thrombin production, potentially treating both hemophilia A and B, including those with antibodies against standard therapy. The treatment could also accelerate clot formation in patients with factor V Leiden, offering a more effective and long-acting alternative to current therapies.
New research reveals that ancient rocks can supply energy to microorganisms kilometers below Earth's surface through reactions between water and minerals. This discovery has significant implications for the search for life on Mars, where similar geological settings may support microbial life.
Scientists have developed a non-toxic strain of Salmonella to target and kill cancer cells, reducing tumor size by 20% in mice with prostate cancer. The bacteria's ability to penetrate cell barriers makes it an ideal candidate for bacteriotherapy, a promising new approach to treating cancer.
Researchers have developed a simple process to create reactive actinide oxide nanocrystals, enabling the production of dense nuclear fuels and potential applications in waste management. This new approach could lead to more efficient and sustainable solutions for nuclear energy.
A new study from the University of Pennsylvania found that competition significantly motivates people to exercise more than friendly support. The study, which recruited nearly 800 Penn students, showed that attendance rates were 90% higher in competitive groups compared to a control group. Meanwhile, team support actually led to lower ...
Researchers attached data loggers to common swifts to track their flight activity, confirming they spend over 99% of their non-breeding period in the air. The birds likely save energy during the day by soaring on upward currents and ascend at dawn and dusk.
A new analysis by NYU's Steinhardt School of Culture, Education, and Human Development reveals that girls outperform boys in math, especially among top achievers. Teachers also lower ratings for girls' math skills when they perform similarly to boys.
A study of 185,419 depression diagnoses in Denmark found that the transition from daylight saving time to standard time leads to an increase in depression diagnoses, affecting all severity levels. The researchers suggest that the loss of morning sunlight and shorter days may contribute to this effect.
A study by researchers at Osaka University and the University of Cambridge found that a 'reorganisation' of the brain's wiring causes phantom limb pain in amputees. They developed an AI-based treatment using brain-machine interfaces to decrease pain levels.
Researchers at PPPL found that mean flow energy is never more than 1% of turbulent energy in H-mode, ruling out the predator-prey model. This result deepens the mystery of H-mode, but may refocus efforts on other contenders for understanding its physics.
Researchers discovered that sharks absorb toxic ammonia through their gills and convert it into non-toxic urea. This process helps maintain the fish's moisture levels in salty seawater.
A coordinated replication effort across 17 labs failed to replicate the 1988 study suggesting that facial expressions can trigger emotional reactions. The multilab study used a standardized protocol with over 1,900 participants but found no evidence that inducing particular facial expressions affected their emotional state.
Scientists created an airway-on-a-chip that simulates the effects of smoking on human lungs, revealing changes in gene expression and cilia beat patterns. The technology also showed promise for testing e-cigarettes and identifying potential therapies for COPD.
Researchers found that underground car parks can act as 'lungs of the city', reducing particulate matter concentrations outside the car parks by up to 50%. The study suggests that implementing air purification systems in parking garages can improve air quality in urban areas.
Researchers developed a three-dimensional mammary gland model that mimics healthy breast tissue structure and function. The model enables the study of disease mechanisms and drug screening, providing a significant breakthrough in understanding breast cancer.
Research shows that people who receive regular dental check-ups have a lower risk of pneumonia than those who don't. Good oral hygiene can limit the quantities of bacteria present, reducing the risk of pneumonia.
The Alliance will develop a nationwide cohort of advocates with expertise in PCOR/CER to address under-representation of older adults and caregivers. The project aims to improve informed health care decisions and increase the usefulness of PCORI's information.
Research by the University of Kent has identified an enzyme, cytochrome bd-I, as crucial for the survival of antibiotic-resistant E. coli bacteria. Targeting this enzyme with new drugs may render these bacteria susceptible to attack from the host immune system.
A new study published in JAMA Oncology found that left-sided primary tumor location is associated with a nearly 20 percent reduced risk of death. This difference was independent of many clinical factors like tumor stage and receipt of adjuvant chemotherapy.
A recent Tansley Review found that cassava yields have stagnated since 1961, with potential for 25-100% improvements in yield, water, and fertilizer use efficiency. Researchers highlight the importance of improving photosynthesis to increase sustainable food productivity.
Tropical Cyclone Kyant formed in the Bay of Bengal on October 25, 2016, and was analyzed by NASA's GPM core satellite. The satellite detected intense storms with heavy rainfall rates of over 215 mm per hour, and some thunderstorms had unusually high storm tops reaching above 20 km.
Simple images designed to convey information about prescription drugs could help save lives by reducing non-adherence to treatment. The study found that including pictograms on written medication instructions helps seniors take their drugs correctly, especially those with lower education levels.
A study found that most pediatric ICU physicians do not use current guidelines to diagnose acute kidney injury (AKI) in critically ill children. The prevalence of AKI among patients in pediatric intensive care units is rising, highlighting the need for improved diagnosis and treatment.
A team of Vanderbilt scientists has developed a bioluminescent sensor that causes brain cells to glow in the dark, enabling researchers to track the interactions within large neural networks. The new technique uses calcium ions to detect neuron activity, offering a powerful tool for studying brain function.
Researchers have identified a protein called PP5 that is significantly upregulated in the lungs of severe asthmatic patients, blocking the effectiveness of anti-asthma drugs. This discovery provides a potential new target for developing novel treatments for severe asthma.
Researchers successfully integrated transplanted embryonic nerve cells into the visual cortex of adult mice, demonstrating functional connectivity and restoration of network function. This breakthrough holds promise for treating acquired brain diseases, including neurodegenerative illnesses and stroke-induced damage.
A study published in The New England Journal of Medicine found that commonly prescribed preventive medicines for pediatric migraines are no more effective than a sugar pill. Instead, a multi-disciplinary approach and the expectation of response may be key to preventing headaches in children and teens.
Researchers at Lomonosov Moscow State University have developed a bolometer device that measures electromagnetic radiation energy flow using graphene oxide. The device operates at room temperature without additional cooling, demonstrating the potential of graphene in practical applications.
Researchers found that removing aging macrophages from atherosclerosis-prone mice reduced plaque buildup by 60%, suggesting a potential cellular target for therapy. The study also showed that suppressing senescence limited disease progression and reduced markers of plaque instability.
The study found that 1% of chimpanzee genomes are derived from bonobos, indicating gene flow events between the species. This discovery has strong implications for chimpanzee conservation, enabling researchers to locate individual chimpanzees by their geographic origin.
Scientists at DIII-D National Fusion Facility have successfully reproduced radiation patterns in simulations, providing a breakthrough in fusion research. By eliminating molecular physics and accurately accounting for divertor plasma parameters, researchers have made significant progress towards designing radiating exhaust solutions.
Astronomers using Kepler and Swift missions discover 18 stars that rotate rapidly, producing X-ray emissions at more than 100 times the sun's level. These stars are believed to have formed from the merger of two sun-like stars in close binary systems.
A review of medical literature found only 92 gold-standard clinical trials on immediate cardiac arrest treatment over the last 20 years, despite 535,000 annual cases in the US. The study highlights a significant lack of research on post-arrest care and long-term survival outcomes.
A study published in Liver Transplantation found that young people with chronic liver conditions have a significantly higher prevalence of depression and anxiety compared to the general adolescent population. The most common concerns reported by these patients are fatigue, sleep difficulties, financial concerns, and low self-esteem.
A recent study found that Medicaid policies requiring tobacco-cessation counseling actually decrease the use of anti-smoking medications among smokers, with a one-quarter to one-third reduction. This is due to barriers erected for smokers who want to quit.
Researchers at General Atomics have developed a gamma ray camera to image energetic electrons in ultra-hot fusion plasma, providing unprecedented insights into their behavior. The device reveals that radiation forces can sap high-energy electrons, while collisions with other electrons are more effective at lower energies.
The University of Montana's Flathead Lake Biological Station has been awarded a $2 million grant to explore the diversity of insects, crustaceans, and other arthropods in river floodplains. The project aims to assess the genetics, populations, and functional trait diversity among floodplain arthropods using novel genomic tools and mode...
A study found that cranberry capsules did not significantly reduce the presence of bacteriuria and pyuria, or the number of urinary tract infections, among older women living in nursing homes. The results contradict previous studies suggesting cranberry products may be effective in preventing UTIs.
A case report reveals that high-dose lutein supplements can cause the formation of crystal deposits in the eyes, highlighting the importance of balanced intake. The study suggests that patients should follow a diet rich in eye-healthy foods and only take AREDS2 supplements as recommended by their ophthalmologist.
Scientists have discovered that plant light sensors also respond to temperature, allowing plants to detect changes in growth conditions. Mutant plants revealed a previously unknown conversion process where thermal reversion occurs without light, affecting the plant's response to temperature and light intensity.
Goldston's paper presented a new model for estimating scrape-off layer width, which depends on plasma drift rate across closed surfaces, and has been largely confirmed by experiments worldwide.
A new study found that injectable contraceptives for men can reduce the risk of unplanned pregnancies in their female partners. The hormone-based method, which involves injecting a combination of progestogen and testosterone, was effective in nearly 96% of continuing users.
A new study from Johns Hopkins Medicine found that while training doesn't change neurological repair in chronic stroke patients, it can help them learn new motor skills and achieve more independence. The researchers used a video game-like test to assess the patients' ability to perform tasks.
Researchers discover that tolerance is induced only when antigens are acquired and presented to T cells by specialized dendritic cells. Dendritic cells also cause short-term activation of T cells under non-infection conditions, but without long-term effects. This improved understanding may lead to new ways to control the immune response.
A new analysis reveals unacceptable mortality rates in young US children with chronic liver disease on transplant waiting lists and after transplantation. Young children with higher pediatric end-stage liver disease scores, lower initial height, and higher weight at listing have a higher risk of mortality.
Researchers have successfully simulated and observed the formation of plasmoids in a tokamak chamber, enabling plasma startup without solenoids. This breakthrough enables future commercial fusion power plants to operate more efficiently.
A new mobile application, DentaCom, captures and transmits images of dental emergencies to provide dentists with the information needed to make decisions. The app guides individuals through a series of questions, allowing them to complete a guided report and take photos within four minutes.
A study of over 150 meth users found that those with impulsive personalities were more likely to start using the drug at an earlier age. The researchers discovered a strong link between attentional and motor impulsivity, which contributed to early meth use.
A team of researchers found that the shape of a tube, in addition to its size, affects whether liquids will spill. When tubes are elliptical or triangular, gravity can't overcome surface tension, causing liquids to remain inside, unlike circular tubes.
A Duke University study reveals that hospital rooms and patients can spread germs through contact with healthcare personnel. The research found that nurses' clothing and patient room surfaces were frequently contaminated with pathogens, highlighting the need for enhanced infection control measures.
Researchers at West Virginia University have directly measured the 3D patterns of flowing plasma striking fusion and space propulsion device walls. The measurements show that plasmas accelerate parallel to the wall before impact, causing rapid erosion of the devices' lifetimes.
A new whole-genome analysis reveals that chimpanzees and bonobos had a historical genetic flow, which sheds light on processes that may have played a recurring role in great ape evolution. The study found evidence of gene flow between the two species between 200-550 thousand years ago.
Researchers at the University of Warwick have developed a blood test to detect early-stage osteoarthritis (OA) and distinguish it from other self-resolving inflammatory joint diseases. The test identifies biomarkers in plasma proteins damaged by oxidation, nitration, and glycation, enabling early detection and treatment.
A new study suggests that global warming above 1.5°Celsius will drastically transform Mediterranean ecosystems, producing species never seen before in the past 10,000 years. The region's biodiversity and services, including clean water and carbon storage, are critical to human well-being.
Researchers found that exhausted T cells, which are supposed to fight cancer, have a distinct epigenetic profile that prevents them from becoming durable memory cells. This limits the effectiveness of checkpoint inhibitors, which temporarily boost their activity but don't lead to long-lasting benefits.
Researchers at UC Davis created a computer model that predicts the behavior of E. coli bacteria, using a massive dataset called Ecomics, which includes profiles of gene expression and protein activity across various conditions. The model, MOMA, can help scientists design experiments and identify key pathways for antibiotic resistance.
The University of Illinois Chicago will send 15-20 UIC undergraduates on a 17-day journey across the Canadian Arctic's Northwest Passage as part of a $3 million NSF-funded project. Students will participate in climate and marine research, learn navigation and sailing skills, and contribute to live broadcasts streaming from the ship.