Typhoon Haima, a Category 4 hurricane, is forecast to affect the northern Philippines as it strengthens. The storm is expected to make landfall in mainland China after passing over northern Luzon.
A clinical trial found no association between caffeine ingestion and arrhythmic episodes in patients with heart failure. The study included 51 patients who received high doses of caffeine or placebo over a five-hour period, with no evidence of an arrhythmogenic effect.
At CHEST Annual Meeting 2016, unusual case reports highlighted foreign object inhalation, where asthma inhaler cap lodged in the bronchus, and a woman coughed out stone after chiseling accident. A patient with substance abuse history swallowed a small metal crucifix, which was successfully removed during surgery.
Sheffield researchers found that replacing lead zirconate titanate with potassium sodium niobate poses significant environmental risks due to heavy metal and radioactive material releases. The study's life cycle analysis revealed harmful effects on air, water, and land quality prior to material use.
Researchers found that retail employees experience corporate hypocrisy through direct managers and corporate offices, leading to negative attitudes and high turnover rates. Good manager training and consistency are key to preventing these issues and maintaining good employee relations.
Two studies found that patients with a higher resting heart rate after an exacerbation are at risk for recurrent exacerbations, while hand grip strength is associated with fewer COPD exacerbations. Muscle weakness is linked to exercise limitation and exacerbations, making hand grip strength a useful marker.
A new method uses genetic algorithms to rapidly identify top materials for pre-combustion carbon capture. A variant of NOTT-101 has been found to have the highest capacity for capturing carbon and good selectivity, meeting the DOE's 90% CO2 removal target.
A recent study reveals that blood-based genomic and proteomic testing can rapidly identify genetic mutations in patients with lung cancer, enabling personalized treatment. This approach significantly reduces the wait period between diagnosis and treatment, improving patient outcomes.
A new mechanism explains how great earthquakes cause coastal uplift worldwide, highlighting the potential for future damaging earthquakes and tsunamis at active subduction margins. Paleoshorelines reveal that recent uplift is often greatest in periods with clustered large-magnitude earthquakes.
A team of researchers at Princeton University has devised a novel pathway for reactivity that bypasses the need for reactive functional groups. The method uses proton-coupled electron transfer to form valuable carbon-carbon bonds, opening up new synthetic opportunities.
New research from the University of Otago suggests that walking after meals can significantly lower blood sugar levels in people with type 2 diabetes. The study found that post-meal physical activity can reduce blood sugar levels by up to 22% compared to taking a single 30-minute walk at any time of the day.
A new meta-analysis suggests that antenatal corticosteroids can improve lung development and reduce severe respiratory distress in preterm babies. The study found a significant reduction in respiratory distress syndrome among babies born between 34-37 weeks, including those delivered via scheduled C-section.
The annual global weight extracted is estimated at 120,000 tonnes of bait worms, with extraction having significant physical impacts on shore sediment and wading bird populations. The researchers encourage sustainable management to minimize environmental impacts.
The National Institutes of Health has awarded a $7.5 million grant to researchers at the University of Michigan to study chronic pain. The team aims to investigate how peripheral damage, inflammation, and central nervous system factors interact to cause chronic pain, with potential breakthroughs in treating high levels of chronic pain
A wearable artificial vision device has vastly improved the daily productivity of visually impaired patients, with an average score of 9.8 out of 10 after one week of use. The device, which clips to glasses and features a miniature camera, recognizes text and faces, and reads them aloud via a bone-conduction earpiece.
A review article explores the ethics of discussing disease prognosis with terminally ill adolescents, emphasizing the importance of gentle but persistent conversation. Clinicians are advised to engage patients directly, allowing time for exploration of values and goals, while balancing the need for truth-telling with emotional distress.
A nationwide CPR training event aims to improve cardiac arrest survival rates. The training has already been delivered to 31,000 children in the past two years and will reach over 100,000 this year. The initiative is part of a collaboration between leading organizations to create a Nation of Lifesavers.
Scientists at University of Würzburg have discovered a third RNA binding protein, ProQ, which controls gene activity and allows bacteria to quickly adapt to changing conditions. ProQ binds to nearly 100 regulatory RNAs in Salmonella enterica, influencing their activities.
Research highlights diabetes as a significant factor in increased fracture risk, with a potential seven-fold higher risk than non-diabetic patients. Current risk factor calculators may not accurately predict fractures in people with diabetes, emphasizing the need for extra vigilance and targeted prevention strategies.
A single home visit significantly increases patient adherence to office visits and inhaler use, reducing severe exacerbations and emergency department visits. After the intervention, patients exhibited a 40% decrease in ED visits and improved maintenance inhaler use.
Researchers at UCLA have identified the structure of a molecule toxic to disease-carrying mosquitoes, including those that transmit dengue fever and Zika virus. The toxin, BinAB, is lethal to Culex and Anopheles species but not Aedes, which carries Zika virus and dengue fever.
A team of researchers used synchrotron x-ray tomography to study a 424 million-year-old fossil fish's jawbone, providing new insights into the origin of tooth replacement. The findings suggest that the process evolved independently in two different groups of early vertebrates, using distinct mechanisms.
Researchers at Saarland University develop artificial cell-like spheres from natural proteins, forming stable bilayers in both aqueous and oily environments. These structures can be used for targeted drug delivery, allowing charged particles to pass through the bilayer in a manner identical to natural cells.
A new study has found that faecal bacterial profiles can be used to predict which IBS patients are most likely to benefit from a low-FODMAP diet. The research identified differences in gut bacteria composition between those who responded and did not respond to the diet.
Researchers found that babies born to women over 40 through assisted reproduction have fewer birth defects than those conceived naturally. The study suggests that IVF treatment may provide more favorable biological conditions for pregnancies in older women.
A recent study reveals that archaic and modern humans co-diverged with a common HPV16 strain, which was then transmitted through sexual contact with Neanderthals. This ancient 'hanky panky' may have influenced the spread of STIs, explaining regional diversity in HPV16 strains.
Researchers from the University of Maryland have observed molecules of double-stranded RNA being passed directly from parent to offspring in Caenorhabditis elegans, suggesting a key mechanism for non-genetic inheritance. The study reveals that dsRNA can silence genes in offspring even if it doesn't match the parent's genes.
A new study reveals a wide range of unexpected authors contributing to psychology research, including politicians, celebrities, and historical figures. Notable examples include Ben Carson, Tim Duncan, and the Dalai Lama.
Researchers have developed a new technology called DarkLight that enables visible light communication even in dark environments. The technology uses ultra-short, imperceptible light pulses and can transmit data over short distances without being blocked by obstacles.
Researchers have identified HDAC7 as a transcriptional repressor involved in B lymphocyte generation and identity. The study reveals that HDAC7 is essential for B cell development, maintaining its lymphoid identity by silencing lineage-inappropriate genes.
A Phase 2 study of a novel colonoscopy prep found it to be at least as effective and safe as existing products, while offering higher levels of patient satisfaction and preference. The investigational treatment allows patients to eat solid food bars and drink palatable beverages, leading to nearly four times more recommendations.
Researchers have discovered that plants can direct their seeds towards suitable sites by wind or water, contrary to previous findings for animal-dispersed plant species. This 'directed dispersal' allows wetland plants to optimize seed transportation and reach new areas for growth.
A Mayo Clinic study found that pregabalin, a neuro-pain inhibitor, may alleviate abdominal pain in patients with irritable bowel syndrome (IBS). The 12-week study showed significant improvement in pain management for those taking pregabalin compared to placebo.
Researchers at Children's Hospital Los Angeles identified a critical role of the MDM2 oncogene in promoting expression of the MYCN oncogene required for retinoblastoma cell growth and survival. The study found that MDM2 promotes MYCN expression, which plays a key role in cell proliferation.
Researchers found that spinal cord injuries cause profound changes in gut microbiota, leading to dysbiosis. However, feeding mice probiotics after a spinal cord injury improves functional recovery and elicits a protective immune response.
A new approach to treat cancer involves depleting CAR T cells after treatment, permanently restoring healthy B cell levels. Researchers created CD19-targeting CAR T cells with an additional EGFR targeting mechanism, eliminating tumors and reversing B cell aplasia in mice.
A study found that mothers with higher BMI before pregnancy have shorter telomeres in their newborns, indicating a link between maternal weight and biological age. This association may increase the risk of chronic diseases in adulthood.
A multicenter study of 1,015 major liver resections found that minimally invasive surgery (MIS) had significantly lower odds of serious morbidity and death in the short term compared to open operations. Risk of complications such as bile leak and readmission were similar between the two procedures.
Researchers at Carnegie Mellon University have developed a new technology called ViBand that enables smartwatches to detect finger taps, flicks, and scratches. This allows for new applications using common gestures to control the smartwatch and other objects connected through the internet of things.
Researchers discovered that leukemia cells don't hide in specific niches but instead move actively throughout the bone marrow. This movement may help them survive treatment and evade targeted therapies.
A UCF team led by Assistant Professor Arkadiy Lyakh has developed a simpler process for creating quantum cascade lasers, offering comparable performance and better efficiency. The new method uses only two different materials, making production more practical.
Obese women who receive bariatric surgery before becoming pregnant have lower rates of cesarean sections and larger babies compared to those who don't. The study found a significant decrease in cesarean deliveries among women who underwent bariatric operations, with only 1% vs 38% in obese women without the procedure.
NASA's Suomi NPP satellite captures visible image of Typhoon Sarika in the South China Sea. The storm is forecasted to make its second landfall near Hainan Island, China, before continuing west and impacting northern Vietnam.
New research from The Wistar Institute found that estrogen signaling is responsible for immunosuppressive effects in the tumor microenvironment across various cancers. This discovery paves the way for combining anti-estrogen therapy with immunotherapeutic treatments to extend survival in patients.
The UK government's shift from harm reduction to abstinence-based policies has contributed to the rising number of drug-related deaths. Experts recommend expanding treatment options and investing in naloxone, safer injecting equipment, and immunization programs to combat the crisis.
Researchers at Hokkaido University discovered that a nonsteroid anti-inflammatory drug used for treating colds can suppress the spread of bladder cancers and reduce chemoresistance in mice. The study identified the metabolic enzyme aldo-keto reductase 1C1 (AKR1C1) as a key player in cancer progression.
Researchers in China developed a 'shadow method' to measure forces acting on water strider legs, revealing key principles behind their locomotion. The technique could help design advanced biomimetic robots and measure forces at the single molecular level.
HIV-infected patients with chronic HBV and HCV coinfection are at a higher risk for non-Hodgkin's lymphoma, a leading cause of AIDS-related deaths. The study found that the incidence rate is 10 times higher in HIV-infected persons compared to the general population.
A new study by Michigan State University researchers demonstrates that digital scans of a young child's fingerprint can be correctly recognized one year later, allowing for proper medical care. The technique has the potential to save millions of lives by tracking vaccination records and providing lifelong identity.
A new study published in CMAJ found no correlation between the day of the week elective surgery is performed and patient risk of death. The researchers analyzed data from 402,899 procedures over 10 years, including variations in surgeon experience and post-surgical care on weekends.
A study published in the Journal of General Internal Medicine found that frequent participation in multiple types of leisure activities reduces heart-related deaths among seniors. Engaging in low-intensity daily physical activity can provide cardiovascular protection.
Researchers at Weill Cornell Medicine found that chemotherapy kills urothelial cancer cells but shapes their genetic evolution, leading to drug-resistant cell clones. This study provides a framework for understanding the biological basis of chemotherapy resistance in bladder cancer and may lead to improved diagnostics and treatments.
A recent expedition to Mindanao, Philippines, revealed 126 species of amphibians and reptiles, including 40 frogs, making up 36% of known Philippine species. The research team used genetic and morphological analysis, international collaboration, and rigorous fieldwork to uncover the island's biodiversity hotspot.
Researchers found that 57% of patients achieved 20/40 vision without glasses or contact lenses after five years, while some side effects included endothelial cell loss. The study suggests Phakic ICLs may be a viable option for those unsuitable for LASIK.
A DGIST research team developed porous acupuncture needles with enhanced therapeutic properties by applying nanotechnology. The findings showed that PANs excel in transferring signals from a spinal dorsal horn and demonstrate superior efficacy in treating addiction in animal experiments.
Trauma centers treating high proportions of uninsured patients would see significant gains in financial margins from Medicaid expansion, according to a nationwide study. The simulation model found nearly three times as many patients would gain health insurance through Medicaid in expansion states than non-expansion states.
A study at Northwestern University found that genetic variants affect how people metabolize caffeine, impacting their coffee consumption habits. The research also discovered a link between caffeine metabolism and nicotine metabolism, with potential implications for precision medicine.
The 'robomussels' have tracked internal body temperature, enabling scientists to pinpoint areas of unusual warming and develop strategies to prevent extinction of certain species. The findings can reveal emerging hotspots, allowing policymakers and scientists to intervene before it's too late.
Researchers found that minimal exercise can regulate insulin levels, maintain metabolic function, and help prevent significant weight gain in postmenopausal women. Sedentary rats experienced a 50% reduction in fat tissue after limited physical activity, highlighting the benefits of any amount of exercise.
Researchers identify two distinct genetic markers, Rspo2 and Ppp1r1b, corresponding to negative and positive neurons in the basolateral amygdala of mice. These neurons regulate behaviors tied to negative and positive stimuli, respectively.