Researchers at University College London have successfully targeted an autoimmune condition in mice using cancer drugs being tripped in human patients. The study found that by blocking a specific genetic key, the immune system's aggressive response could be prevented, reducing inflammation and damage.
A study published in JAMA Oncology shows that intrinsic molecular subtyping of breast cancer can predict patient outcomes and guide treatment decisions. The research found that the genomic classification of tumors is a key prognostic factor, outperforming traditional variables such as age and number of metastases.
Researchers found that basaltic rocks can effectively store carbon dioxide, a potential solution to mitigate climate change. By injecting CO2 into these rocks, the greenhouse gas is converted into stable carbonate minerals, reducing leakage risks.
Researchers found a distinctive pattern of injury in the brains of deceased military personnel who survived high explosive attacks, suggesting a link between blast exposure and neuropsychiatric symptoms. The study's findings highlight the need for further research to understand the underlying pathophysiology of traumatic brain injury.
The Rutgers scientists reveal how a transcription activator protein interacts with RNA polymerase and DNA to initiate transcription. The discovery provides a molecular picture of transcription activation at a target promoter.
Exposure to LED light for just four hours can make milk taste like cardboard, while older milk remains at high quality for two weeks when shielded from LED exposure. Consumers overwhelmingly prefer older, fresh-looking milk over newer, LED-exposed milk.
Researchers found that Candida-specific CD4 T cells are more susceptible to HIV infection and preferentially depleted earlier than CMV-specific cells. This sequential dysfunction may lead to the early loss of immune control over mucosal candidiasis in HIV-infected individuals.
Chem, Cell Press' new physical sciences journal, aims to move the field forward through original research articles, reviews, and front matter. Key findings include transporters with high selectivity for chloride over other ions, stable phosphorous carbene analogs, and strategies for producing chemicals from renewable sources.
A new treatment uses chemotherapy followed by autologous haematopoietic stem cell transplantation to fully halt clinical relapses and development of new brain lesions in patients with multiple sclerosis. Eight patients showed a sustained improvement in disability 7.5 years after treatment.
Researchers at Karolinska Institutet identified 12 subclasses of oligodendrocytes and a novel cell distinct from oligodendrocytes residing in blood vessels, uncovering unexpected diversity within the nerve-insulating cells.
A recent study published at EULAR 2016 found that patients with osteoarthritis (OA) are more likely to have their condition underestimated by rheumatologists than those with rheumatoid arthritis (RA). The study highlighted the importance of understanding the impact of disease severity on treatment compliance and future outcomes. Resear...
Researchers used advanced MRI to predict which concussion patients would fully recover and identify brain areas involved in the repair process. The study found that high FA white-matter areas correlated with better outcomes, while low FA areas showed axon damage and cognitive impairment.
Researchers have discovered essential proteins controlling cellulose assembly, enabling improved biomass production and guiding plant breeding for wood and ethanol applications. The findings aim to reduce greenhouse gas emissions by up to 85% compared to fossil fuel sources, providing a sustainable alternative for the industry.
A new study has confirmed a direct link between air pollution exposure and lupus disease activity in children and adolescents. The study found that fine pollution particles triggered an increase in disease severity, including worsening of renal and haematological involvement.
Physicists at NIST create a quantum simulator by entangling up to 219 beryllium ions, enabling simulations that challenge classical computers. The technique also helps improve atomic clocks and models complex physics phenomena.
Scientists at the Hellisheidi power plant in Iceland have developed a method to convert CO2 emissions into solid minerals within months, significantly faster than predicted. The process involves mixing CO2 with water and injecting it into volcanic basalt, resulting in the formation of whitish, chalky minerals.
A team of researchers has developed a method to precisely alter the quantum mechanical states of electrons in an array of quantum boxes. This allows for the investigation of interactions between various types of atoms and electrons, crucial for advancing quantum technologies.
A special issue of Deep Sea Research II explores the global issue of chemical munitions dumped at sea, finding that while some munitions pose little risk to humans, others can have adverse effects on fish populations. International collaboration has shed light on techniques for investigating munitions dumpsites and mitigating damage.
A study found that isolated Cape honeybees in South Africa reproduce asexually, with female workers laying eggs fertilized by their own DNA. This unique behavior is linked to genetic differences at several genes, enabling social parasitism and population survival.
Heavy rainfall from Tropical Storm Colin led to widespread flooding in Florida and Georgia, with over 250 mm of rain recorded in some areas. NASA's IMERG data analysis showed Colin's heaviest precipitation occurred over central Florida, with extreme amounts exceeding 280 mm.
A new laboratory test developed by Johns Hopkins Medicine accurately clocks the 'speed' of human brain tumor cell movement, which may predict how quickly and aggressively a given cancer might lethally spread. The assay has been tested on 14 glioblastoma patients and showed promising results in predicting clinical outcomes.
A 15-year study of 1.1 million patients with atrial fibrillation found that women are 23% more likely to be hospitalised for acute ischaemic stroke than men, regardless of age, ethnicity, socioeconomic status, or region. Women consistently had a higher risk of stroke hospitalization than men over the past 15 years.
An international team of scientists has found a way to remove anthropogenic carbon dioxide emissions from the atmosphere by turning it into rock. The process, known as carbonate mineralisation, can take as little as two years and permanently locks away CO2 in basaltic rocks.
Researchers discovered an enzyme that slows cell growth in breast cancer cells by increasing cyclic GMP production. Histone deacetylase inhibitors also relax blood vessels, suggesting potential therapeutic applications for erectile dysfunction and other diseases.
A new study links melting in Greenland to Arctic amplification, a phenomenon fuelled by rising global temperatures and melting sea ice. The jet stream's northern swing reached record-breaking latitudes, allowing warm air to penetrate further north.
Researchers identified and recorded over 50 species of fungi, algae, cyanobacteria, lichens, and vascular plants at the Mars Desert Research Station. The study provides a first-line reference for identifying these organisms and serves as a starting point for future floristic and ecological work.
By immersing glass particles in a fluid, researchers enhanced the optical properties of both solids and liquids, demonstrating significant changes in diffusivity. The findings have potential applications in imaging, sensing, and photography, including calibrating medical-imaging systems and creating tunable optical devices.
Researchers have identified a genetic mutation in the TEK gene that causes primary congenital glaucoma, a devastating eye disease affecting children worldwide. The finding validates previous research in mice and suggests a new therapeutic pathway to repair damaged vessels in the eye.
A new mouse study suggests that autism spectrum disorders (ASDs) may be linked to defects in peripheral nerves, rather than just the brain. The research found that mice with ASD-associated gene mutations exhibited abnormal touch sensitivity and anxiety-like behavior.
Scientists at the University of Utah found that delaying the budding of new HIV particles triggers protease to destroy the virus, rendering it non-infectious. This breakthrough could lead to the development of new AIDS treatments with fewer side effects in about a decade.
Researchers found that birds flee from predators at longer distances when their eggs are well-camouflaged, and adjust their behavior to shade their eggs during the day. This suggests that camouflage can mitigate both predation risk and thermal risks in animals.
Researchers found that 30% of induced pluripotent stem cells were genetically unstable and not safe for clinical use. Despite this, a large set of iPSCs met quality standards, and the study established an online database to support further research.
A clinical trial shows that an intensive procedure replacing the diseased immune system with a new one using blood stem cells can eliminate all signs of brain inflammation in people with early, aggressive multiple sclerosis. The treatment resulted in zero clinical relapses and no new active inflammatory lesions over 4-13 year follow-up.
A study found that about 40% of Hispanic adults with colorectal cancer used complementary and integrative health practices. Women were more likely to have used these practices than men, according to the study published in The Journal of Alternative and Complementary Medicine.
A team of researchers has pinpointed the genetics behind a select group of garter snakes' ability to eat poisonous newts, revealing an evolutionary 'building blocks' pattern. The study found that resistant muscle evolved after resistant nerves, with the ancestors of garter snakes gaining toxin-resistant nerves almost 40 million years ago.
Dr. Katherine Ralston, a UC Davis microbiologist, has been awarded a 2016 Pew scholarship to study the mechanisms of 'trogocytosis,' or 'cell nibbling,' which allows Entamoeba histolytica to kill cells in the human intestine. This research could lead to new insights into disease prevention.
A study found that breast cancer patients who did not adhere to their medication schedule for chronic conditions before diagnosis were twice as likely to skip oral adjuvant hormonal therapy. Non-adherence rates were higher among women with certain age groups, medical specialties, and co-payments.
Researchers found that DNASE1L3 prevents lupus by breaking down DNA, which triggers immune cells to produce antibodies that cause inflammation. A new mechanism for biologic therapies has been discovered.
Researchers at the University of Pittsburgh have developed a unique method to detect antibodies in the blood, enabling simple diagnostic tests for diseases without known microbial causes. This approach successfully led to the detection of HIV antibodies and holds potential for diagnosing various conditions with just a single drop of bl...
Researchers have developed perovskite solar cells with an average efficiency of 19.6% and a record-breaking aperture area of 1 cm2, overcoming scalability limitations. The new technique eliminates impurities and grain boundaries, resulting in highly oriented crystalline films.
A new study provides direct evidence of the brain's navigation network, including the orbitofrontal cortex and frontopolar cortex. The research found that these regions play key roles in classifying future goals and visualizing spatial contexts for navigation.
A new study reverses resistance to antiangiogenic drugs by adding an antidiabetic agent, inhibiting tumor growth up to 92%. Researchers found that this mechanism can be targeted to attack cancer cells, with potential for improved treatment outcomes. The discovery has the potential to prolong patient benefit from antiangiogenic treatments.
Researchers at Aarhus University have developed an RNA aptamer that prevents misfolding of a specific serpin mutant without inhibiting its anti-proteolytic function. This breakthrough has implications for diseases caused by serpinopathies, such as liver cirrhosis and lung emphysema.
Researchers found that expensive drugs like aflibercept are not cost-effective for treating diabetic macular edema compared to cheaper alternatives. To reach a threshold of $100,000 per quality-adjusted life-year, treatment costs would need to decrease by 69% for aflibercept and 80% for ranibizumab.
EPFL researchers have achieved the highest performance ever measured for larger-size perovskite solar cells, reaching over 20% efficiency. This breakthrough could lead to increased efficiency in hybrid solar panels that combine perovskites with silicon, potentially exceeding 30% efficiency.
A recent study confirms a strong association between depression symptom severity and the level of disease activity and disability in adolescent patients with juvenile inflammatory arthritis. The findings underscore the need for psychological health assessment and support to be fully integrated into their routine care.
Researchers at Washington State University have observed skin cells altering proteins and moving to repair wounds, a process that could be manipulated to speed up healing. They found that the cells use their internal muscle-related proteins to generate forces needed to move, allowing them to 'walk' to the wound site.
Scientists have identified a new biomarker for nerve cell damage that can be measured in the blood, providing valuable information on disease progression and treatment response. The discovery offers a potential breakthrough for developing therapies and could simplify clinical trials by using a simple blood sample.
A new method enables rapid isolation and concentration of infectious bacteria from complex clinical samples, accelerating bacterial identification and antibiotic susceptibility testing. This breakthrough uses an engineered pathogen-binding protein to capture live pathogens from joint fluids, allowing for faster and more accurate diagno...
A new drug called ixekizumab has shown significant promise in treating moderate to severe psoriasis, with 80 percent of patients experiencing complete or near-complete clearance of their symptoms. The long-term efficacy and safety of the treatment will be monitored closely.
A heart monitor implant has been shown to detect potentially fatal cardiac arrhythmias in patients with systemic sclerosis, a serious immune disease. The device can store ECG data automatically and pick up various heart rhythm abnormalities in over half of the cohort of SSc patients.
A study at Henry Ford Hospital found that showing magnified images of bacteria on common objects like mouse pads and hands improved hand hygiene compliance. Compliance rates increased significantly across four patient care units, with some units seeing as much as a 142% increase.
A Stanford University study found that the majority of California and Hawaii residents supported physician-assisted death, with no significant differences in support across ethnicities. Older adults were more likely to support the practice, while those who reported less importance of spirituality were more likely to be supportive.
Early findings suggest carfilzomib may provide improved reduction of antibodies in potential kidney transplant candidates with reduced side effects. The study's preliminary data show antibody reductions between 31 to 100 percent in the first group of six patients.
The study estimates that there are over 72,000 cases of unrepaired cleft lip and/or palate in India, with rates ranging from less than 3.5 per 100,000 population in Kerala and Goa to 10.9 per 100,000 population in Bihar.
The Pew Charitable Trusts has named 22 exceptional early-career scientists as Pew scholars in the biomedical sciences. These researchers will receive flexible funding to pursue innovative research, joining a community of scientists dedicated to collaboration and mentorship.
Researchers developed synthetic transporters that can carry chloride through lipid-bilayer membranes, potentially replacing faulty channels in cystic fibrosis. The new molecules show high selectivity for chloride over protons and hydroxide, addressing a potential toxic effect.
A new study reveals that more than 47 percent of female veterans experienced insomnia symptoms resulting in functional impairment. The research identifies subgroups of women at high and low risk for insomnia symptoms.
Researchers at UC San Diego, MIT, and Harvard have engineered 'topological plexcitons,' energy-carrying particles that enhance exciton energy transfer, leading to improved solar cells and miniaturized optical circuits. The discovery provides a directionality feature for efficient energy distribution in nanoscale materials.
Researchers developed a compound that transforms near-infrared light into broadband white-light, emitting directional and high-quality light suitable for microscopes and projection systems. The material is cheap, readily available, and easily scalable, opening up new routes for advanced directed illumination technologies.
A study published in Archives of Sexual Behavior found that behaviorally bisexual men avoid disclosure due to stigma and homophobia, fearing ridicule, rejection, and victimization. The researchers suggest public education campaigns to dispel myths about bisexual men and strategies to minimize negative reactions.
Researchers at the University of Cincinnati found that a pre-procedure medication regimen can significantly reduce hospital stays and readmission rates for liver cancer patients undergoing DEB TACE treatment. The study involved 113 procedures in 71 patients, with only 5% requiring hospital admission due to post-procedural syndrome.
A new study published in The Lancet Neurology reveals that air pollution is a major contributor to stroke worldwide, accounting for nearly a third of the global burden. Modifiable risk factors such as smoking, poor diet, and low physical activity are also significant causes of stroke.
Faulty assumptions about addressing minority patients' needs underlie persistent racial/ethnic disparities in mental health and substance use disorders. The article recommends tailoring care, responding to patient needs, and expanding the workforce to reduce disparities.
A study found that women with systemic lupus erythematosus (SLE) have a doubled risk of pre-malignant cervical changes and potentially an increased risk of cervical cancer compared to the general female population. Regular cervical screening is crucial for women with SLE, regardless of treatment
Silva-Valenzuela will work in the laboratory of Andrew Camilli to determine which types of bacteriophages can effectively eliminate the cholera bacteria in water. The team aims to develop a novel approach to prevent cholera outbreaks.
The Pew Charitable Trusts has announced the selection of five early-career cancer researchers, who will receive four years of flexible funding to conduct their work. The selected scientists aim to unravel the mysteries of cancer by studying medulloblastoma recurrence and developing new immune therapies against pancreatic cancer.
A study of over 1,100 patients with symptoms of gonorrhea or chlamydia found that 76.6% who received antibiotics tested negative for the STDs. The study suggests focusing on clinical predictors may improve unnecessary antibiotic prescribing in patients without true disease.
A new study reveals a link between melting Greenland ice and faster Arctic warming, with significant implications for sea level rise and ocean circulation. The research found that a unique atmospheric pattern led to record-breaking melt in northern Greenland during the summer of 2015.
A new study found that short blue light exposure can lead to increased brain activity in specific regions and improved reaction times for over 40 minutes after exposure. The research suggests that blue-enriched white light could be used to enhance alertness and quick decision making in various settings.
A 3-inch monogamous hermaphrodite fish has evolved a unique reproductive strategy, trading male and female roles to fertilize eggs equally. This behavioral study reveals that long-term partnerships among animals prioritize fairness and cooperation.
A new study maps the geographical ranges of Aedes aegypti and Aedes albopictus mosquitoes, which transmit dengue, chikungunya, and Zika viruses, across 183 counties in 26 states and 1,241 counties in 40 states.
A new study reveals that large marine and terrestrial species are in 'double jeopardy' of extinction, with economic value driving risk above a certain threshold. The analysis highlights the importance of considering trade and differences between terrestrial and marine animals when designing effective conservation strategies.
The LawSeqSM project aims to clarify current genomic law, address gaps, and generate recommendations for a forward-looking legal foundation. This 3-year project brings together experts from academia, industry, and clinical care to create guidance on translating genomics into clinical application.
New research reveals that hierarchy in biological networks arises due to cost constraints on connections, leading to more efficient networks. This finding may accelerate the development of complex computational brains in AI and robotics.
A national assessment of metal contamination in bats reveals high levels of metals such as lead, copper, and cadmium that can cause toxic effects in bat populations. Around 21% of sampled bats contained residues of at least one metal above toxic thresholds, indicating a significant proportion may be affected by metal exposure.
Researchers are exploring ways to introduce blackcurrant pomace into bread and breakfast foods to enrich their fibre content. The project aims to find methods of introducing the pomace, which is a rich source of polyphenols and fibre, into cereal products.
Scientists uncovered century-scale patterns in Pacific rainfall and temperature linked to global climate changes over the past 2000 years. El Niño-like states have amplified global climate fluctuations, with northern hemisphere warming and droughts corresponding to an El Niño state from 950 to 1250.
University of Oregon scientists have synthesized a stable biradical compound with two free-flowing, non-bonding electrons. The molecule can change its bonding patterns to a magnetic state when heated, but returns to a fully bonded non-magnetic closed state at room temperature.
Researchers from Michigan State University create a new model to estimate summer monarch abundance in Ohio and Illinois through their migration through Texas. Higher populations are associated with average to above-average precipitation and cooler temperatures in Texas during spring.
Researchers created a detailed, high-resolution simulation of weather patterns in the Western US using data from tens of thousands of personal computers. The analysis showed impacts of terrain on local weather and improved accuracy for regional climate predictions.
A new study from RIKEN Center for Sustainable Resource Science reveals that amino acid sequences are key determinants of silk fiber material properties. The research sheds light on the unique properties of silkworm silks, including their mechanical and thermal behavior.
Researchers have developed nanoparticles that can selectively deliver drugs to inflamed joint tissue, improving tolerability and reducing treatment costs. This breakthrough offers new hope for patients with rheumatoid arthritis, allowing for early diagnosis and targeted therapy.
Researchers at Mount Sinai have shown how infected immune cells directly transmit newly minted viral particles to uninfected sister cells, spreading the virus efficiently. This study highlights cell-to-cell transmission as a key route for HIV spread and may help develop new treatments.
Researchers in Madrid are working on a three-year project to improve laws regarding disability, focusing on universal design and accessibility. They aim to integrate all stakeholders and create new specialists in disability support, while analyzing existing regulations and proposals to develop alternative frameworks.
The QUTIS group and Google have collaborated on a pioneering experiment that digitizes analogue quantum computation using superconducting circuits. This breakthrough enables the universal solvability of optimization problems, useful in finance, materials science, and pharmaceuticals.
A new breath test has been developed to identify lung cancer after surgery, using a simple, affordable process that analyzes carbonyl volatile organic compounds in exhaled breath. The test shows great potential for detecting lung cancer at any point, both as primary screening and post-surgery monitoring.
The US policy on mitochondrial replacement therapy (MRT) is at a standstill due to a contradiction between the National Academies' recommendation and a legislation enacted by President Obama's administration. MRT aims to replace disease-causing mitochondrial DNA in human embryos, providing new cures for previously untreatable conditions.
A prospective observational study of 19,815 adults found that those with higher fitness levels had a 37% lower risk of stroke after age 65. The study's findings support the independent role of exercise in preventing stroke and reinforce the benefits of being physically fit throughout life.
High-intensity femtosecond laser pulses can cause DNA breaks and damage, with OH radicals being more likely to produce double strand breaks. The extent of damage can be controlled by varying the focal length of the focusing lens.
Researchers found that Lake Michigan painted and snapping turtles carry all eight metals, with concentrations correlating with soil assessments in the wetlands. The turtles' long lifespan and position in the food chain make them useful indicators of wetland pollution, potentially posing a health risk to humans who consume them.
A University of Liverpool study found the NHS Health Check programme is not supporting the UK population's cardiovascular health. Researchers suggest a new strategy combining structural interventions with screening in deprived areas could maximize effectiveness and equity.
A new study from UTMB reveals that pulmonary rehabilitation therapy is underutilized despite its health benefits and cost-effectiveness in managing chronic obstructive pulmonary disease. The study found that the majority of economic burden of COPD stems from hospitalizations, which can be reduced by PR.
A study found that patients with rheumatoid arthritis (RA) who are positive for the anti-CCP antibody respond better to abatacept, a T cell co-stimulation blocker. In contrast, patients without this antibody do not show significant differences in treatment response to TNF inhibitors.
A diet lacking in zinc is detrimental to human and animal health due to impaired digestion. Even slight zinc deficiency impairs pancreatic digestive activity and results in significant digestive impairment at an early stage.
Researchers develop a new method to analyze genetic sequences, known as SURVIV, which can predict cancer patients' survival times with greater accuracy. This technique may also enable doctors to target specific genetic sequences that could fight disease, according to the study published in Nature Communications.
UC Riverside researchers found that Toxoplasma infection disrupts neurotransmitters in the brain, leading to neurological disease in predisposed individuals. Treatment with ceftriaxone restored GLT-1 expression, reducing extracellular glutamate and normalizing neuronal function.
The Global Alliance for Genomics and Health presents a vision for a common framework of principles, protocols, and interoperable systems to enable responsible data sharing. The alliance has created tools such as the Genomics API and the Framework for Responsible Sharing of Genomic and Health Related Data.
Researchers at ULB developed new methods to determine stem cell multipotency and unipotency with high confidence. The findings show that prostate cells are multipotent while mammary gland cells are unipotent, resolving a long-standing debate in the field.
A review of physical employment standards aims to improve age- and sex-neutrality and address nutritional health, hydration, protective clothing, and load carriage. The special issue consolidates international perspectives on best practices in employment standards.
Experts agree that there is no place for students to fear expulsion due to their sexual orientation in CACREP-accredited programs. Protections for both religious liberties and sexual minorities can coexist, the experts argue.
Research found that young people with older friend connections exhibit reduced ageism, even without direct experience. Knowing positive relationships among peers expands acceptance of older adults.
Research identifies genetic basis for social parasitism in Cape bees, where worker bees can reproduce asexually. The study reveals that multiple genes are required for this trait, including those involved in hormonal signaling and chromosomal segregation.
A new mutation in the ZBTB7A gene boosts energy metabolism in leukemia cells, promoting their growth and survival. This discovery offers a promising therapeutic target for treating acute myeloid leukemia (AML) patients.
A new study presents a visual trigger approach that leverages the 'ick factor' to motivate hospital staff to comply with hand hygiene guidelines. The program, tested on units with low compliance rates, showed significant increases in adherence, with compliance rates rising by 11-46 percentage points.
A new study finds that mental health professionals overestimate their ability to identify mentally ill patients who may engage in firearm violence. The researchers conclude that mental health professionals need more training on firearms issues to prevent firearm trauma by the mentally ill, with a focus on firearm suicides.
Researchers have unraveled how pre-leukemic white blood cell precursors become leukemia stem cells by targeting the RNA editing enzyme ADAR1. Inhibiting ADAR1 can counteract its effect on leukemia stem cell self-renewal, potentially reducing cancer progression.
The Pew Charitable Trusts announced ten innovative postdoctoral scientists from Latin America who will receive two years of funding to pursue research at US laboratories and academic institutions. The program aims to expand frontiers in biomedical science, improving human health and well-being globally.
Researchers are designing cooperative robots to empower people with disabilities to safely travel and navigate unfamiliar environments. A gaze-controlled robotic system is also being developed to enable people with motor impairments to fetch objects by looking at them.
Researchers found that people who take photos of their experiences enjoy them more than those who don't. Photo-taking increases engagement, making the experience more pleasurable. However, the effect is limited to active participation and not when taking pictures interferes with the experience.
Astronomers have found evidence for a tightly orbiting gas giant, PTFO8-8695 b, which is being torn away by its 2 million-year-old star. The planet's outer layers are likely to be destroyed, and its ultimate fate remains uncertain.
A new computer algorithm enables scientists to use satellite data to determine groundwater levels across larger areas than ever before. The technique, developed at Stanford University, could lead to better models of groundwater flow and monitoring in agricultural regions. The team was able to calculate surface deformations and groundwa...
A study by Ting Luo examines the value of dynamic forecasting in intermodal management, finding it reduces holding costs and ensures swift stock buildups for imminent shortages. Dynamic forecasting guides policy formulation, particularly when customer heterogeneity is high, inventory costs are low, and forecast accuracy is high.
Researchers found that faster intestinal calcium absorption and increased urinary excretion of calcium may predispose hypercalciuric patients to developing kidney stones. Measuring these factors could help identify individuals at risk, allowing for early prevention and treatment.
A study presented at EULAR 2016 found that patients with antibodies to biological infliximab are less likely to benefit from infliximab biosimilar (CT-P13). The presence of these anti-infliximab antibodies can lead to a loss of response and increased risk of side effects. The findings suggest that antibody-positive patients should not ...
Research published in Frontiers in Psychology found that people who witnessed a crime can identify criminals through their distinctive scent. Human nose-witnesses were able to correctly identify perpetrators in almost 70% of cases, showing promise for forensic applications.
Research finds that skilled readers don't need to 'sound out' words they know, with a separate area for visual dictionary-like recognition. A different region processes sounds, explaining why people with dyslexia struggle with reading.
A large-scale proteomic study using SWATH-MS technique reveals specific proteins responsible for fat and energy metabolism in mice. The researchers found that COX7A2L protein plays a crucial role in mitochondrial function and its deficiency can lead to metabolic disorders.
Seven pioneers in HIV/AIDS and epigenetics research receive NIDA's Avenir awards to support groundbreaking projects using genome editing, smartphones, and smart health technologies. These early-stage investigators will receive up to $300,000 per year for five years to advance addiction science.
The US healthcare system has significant environmental and health impacts, contributing to greenhouse gas emissions and air pollutants. Researchers estimate 8% of national emissions come from the sector, while healthcare-related emissions linked to respiratory disease, cancer, and acid rain are substantial.
A study by UC Berkeley Haas School of Business reveals how social comparison preferences and conspicuous conservation shape product innovation, leading to eco-friendly developments. The research found that companies can tap into these consumer behaviors to enhance their products' desirability and sustainability.
Researchers at University of California - Davis Health found that patients with late-stage lung cancer who undergo surgery have better survival rates than those who don't. However, only 11% of these patients receive surgery, highlighting a need for improved access to care.
Paul A. Northcott, a researcher at St. Jude Children's Research Hospital, has been selected as a Pew-Stewart Scholar to tackle medulloblastoma, the most common malignant pediatric brain tumor. The award includes four years of funding and aims to develop much-needed therapies for patients who relapse.
Researchers identified a new mechanism by which streptomycin kills bacteria, targeting the MscL channel pore. Dihydrostreptomycin directly binds and modifies MscL, allowing solutes to exit the cell. This discovery holds promise for developing new antibiotics to combat drug-resistant infections.
A new study published in Biological Psychiatry suggests that glial energy metabolism plays a critical role in addiction-related behaviors. Researchers found that altering glial lactate release and nerve cell uptake of lactate prevented long-lasting relapse in rodents.
A recent study found that children with Juvenile Inflammatory Arthritis (JIA) have a significantly higher prevalence of Type 1 diabetes compared to the general population. The research, which included over 9,000 patients, suggests that understanding this link may lead to new treatments and preventative interventions for both diseases.
Researchers reconstructed ancient bacterial enzymes and found that they were sophisticated and functional, contrary to the widely-held theory. This discovery suggests that biological evolution progressed rapidly in its early stages, with enzymes becoming fully developed within a 500-million-year period.
A newly developed PsA-comorbidity index (PsACI) can identify PsA patients at greater risk of hospitalisation and premature death. The index is expected to improve patient outcomes and reduce costs.
Jerry Franklin, a professor at the University of Washington, has been named 2016's Eminent Ecologist by the Ecological Society of America. He is credited with pioneering research on old-growth forests and challenging clear-cutting practices to promote healthy forest ecosystems. His work has had a significant impact on forestry and fore...
A recent study found that patients with rheumatoid arthritis who are obese and smoke have a lower chance of achieving sustained remission after treatment. Encouraging patients to quit smoking and maintain a healthy weight could improve their symptoms. The findings highlight the importance of lifestyle factors in managing the disease.
A new study provides evidence linking melting in Greenland to Arctic amplification, with a northern swing of the jet stream reaching latitudes never before recorded. The study's findings fit the anticipated effects of Arctic amplification, which fuels a feedback loop of rising global temperatures and melting sea ice.