A team of Japanese researchers revealed the mechanism for fever and bone pain caused by G-CSF, which is essential for treating hematological malignancies. The study found that PGE2 produced by neutrophils governed by sympathetic nervous system is behind the unpleasant symptoms caused by G-CSF.
A new study from Tufts University found that learning through practice testing can protect memory against the negative effects of stress. Participants who used retrieval practice showed no impairment in memory after experiencing acute stress, while those who used traditional study practice remembered fewer items overall.
EPFL scientists developed a new perovskite material with rapid and reversible magnetic properties, enabling high-density data storage systems. The material's unique photovoltaic properties allow for easy manipulation of its magnetic order via light illumination.
A team of researchers led by Alena Gsell tested four statistical indicators to predict regime shifts in lakes. While some indicators showed promise, predicting crisis points was not always successful. Collecting more frequent and advanced data could improve early warning systems for lake ecosystems.
Researchers have demonstrated a new type of quantum liquid or quantum droplet state where atoms preserve their form in absence of external confinement due to quantum effects. The discovery opens up a new research area in ultracold quantum gases and may contribute to increasing our knowledge of superfluidity.
A study by King's College London found that black men face barriers to participating in prostate cancer research, including mistrust of researchers and a preference for traditional medicines. The researchers suggest community-driven engagement and dissemination of reliable information as ways to improve inclusion.
Researchers at Duke-NUS Medical School have discovered how the human antibody C10 prevents Zika infection by locking proteins into place, preventing viral DNA entry. Disrupting fusion with C10 may be more effective than targeting docking in preventing Zika infection.
Researchers have identified four new species of parasites infecting an invasive freshwater fish in Japan. The discovery sheds light on the role of parasites in natural ecosystems and their potential impact on native species.
Researchers Jean-Claude Kieffer and François Légaré from INRS receive peer recognition for their groundbreaking work in ultra rapid laser technology. They have been elected into the Royal Society of Canada's Mathematical and Physical Sciences Division.
Microorganisms like fungi and bacteria produce volatile compounds that boost plant growth, flowering, and reserve substance accumulation. This discovery could lead to eco-friendly alternatives to conventional agrochemicals.
Researchers conclude that vitamin D supplementation does not improve musculoskeletal outcomes such as falls or fractures. For those at high risk of deficiency, sunlight exposure and diet should be prioritized, with low-dose supplements considered on an individual basis.
Researchers developed bio-signal measuring electrodes that can be mounted on IoT devices, allowing for easy health diagnosis without additional equipment. The electrodes can measure brain waves, electrocardiograms, and other biological signals, and are expected to be applicable to medical fields.
New research identifies nitrogen as a key driver for gut health, revealing how diet impacts the microbiota. The study suggests that the availability of intestinal nitrogen to microbes is crucial in shaping the microbiome.
Researchers found that dogs can recall a person's complex actions, even when they don't expect to be tested. The study used the 'Do as I Do' training method to demonstrate this ability.
A study published in the Journal of Clinical Psychiatry suggests that home-based telemental health for depression can deliver a similar quality of life and patient satisfaction as in-person visits, overcoming barriers such as mobility issues and transportation costs. The trial enrolled 241 depressed elderly veterans who received eight ...
Researchers at TSRI developed a vaccine that blocks the pain-numbing effects of oxycodone and hydrocodone in animal models, also decreasing the risk of fatal opioid overdose. The vaccine uses the immune system's ability to recognize and neutralize invaders, potentially depriving users of euphoria.
Research by Larry Martinez at Portland State University found that transgender employees' feelings of job satisfaction and alignment with their organizations increased as they transitioned further. Supportive coworkers who validated their preferred gender identity were key to more positive attitudes.
A team of researchers successfully completed the largest known instance of transparent checkpointing using 32,768 CPU cores and 38 terabytes of memory. This breakthrough simplifies the work of computer scientists handling large amounts of data, allowing them to process and analyze billions of pieces of weather data without fear of loss.
Researchers have successfully used Bdellovibrio bacteriovorus, a predatory bacterium, to clear multi-drug resistant Shigella infections in zebrafish. The bacteria works alongside the host's immune system, showing promise as a living antibiotic for tackling drug-resistant Gram-negative bacterial infections.
A team of scientists has developed an equation to measure soil physical quality, which can help determine the best use of a particular soil. The research, led by Robson Armindo, found that this approach can save time and money in crop production.
Researchers identified altered proteins affecting gene expression as the driving force behind childhood ependymomas. This discovery provides a critical marker for predicting prognosis and offers a potential new therapy target.
A study published in JAMA Oncology found that Medicare beneficiaries without supplemental insurance incur average annual out-of-pocket costs ranging from $2,116 to $8,115. Hospitalizations are a major driver of these costs.
The Internet of Things (IoT) will require new search mechanisms to support billions of connected devices, demanding machine-to-machine searches and secure data access. Complex IoT technologies like smart cities, autonomous cars, and environmental monitoring need efficient indexing and ranking mechanisms.
Michigan State University researchers received a four-year, $2.2 million grant to develop kindergarten curriculum units that integrate science with literacy standards. The pilot project found that kindergartners who participated in the program outperformed their peers on tasks requiring evidence-based claims and science vocabulary usage.
Scientists have developed haptic interfaces to enhance collaboration and data analysis in X-ray crystallography. The technology enables real-time visualization and classification of experimental crystallization data on a cloud-based database, streamlining the process and reducing manual effort.
Research warns that hurricanes are moving further north along the Northeast US coast, posing a greater threat to cities like New York. The study suggests that man-made emissions have overridden natural cooling effects, leading to more frequent and powerful storms.
A large study published in The BMJ found that prediabetes, defined as impaired fasting glucose or impaired glucose tolerance, is associated with an increased risk of cardiovascular disease and all cause mortality. The study's findings support a lower cut-off point for defining prediabetes, including as low as 5.6 mmol/L.
The study found that benzodiazepine and related drug use increased the risk of hip fracture by 43% in persons with Alzheimer's disease. Long-term hospital stays after hip fractures were also more common among those who used these drugs.
Researchers develop optical fingerprint to study Salmonella biofilms, providing new tool for understanding mechanisms of biofilm formation. The method is specific and non-toxic, allowing for the detection of biofilm components without harming bacteria.
The spherical mechanical seal's performance is influenced by structure size, including radius, stator-ring distance, and diameter. Increasing the spherical radius reduces contact area but raises temperature and pressure.
Researchers reconstructed the African dust plume over the last 23,000 years and observed a dramatic reduction in dust beginning around 11,000 years ago. This weakened plume may have allowed more sunlight to reach the ocean, increasing its temperature by 0.15 degrees Celsius, leading to an increase in monsoon rains over North Africa.
A pioneering study of invertebrates has uncovered 1445 viruses, including several new families, revealing people have only scratched the surface of the world of viruses. The research, led by Professor Edward Holmes, suggests these viruses have been associated with invertebrates for potentially billions of years.
Researchers found a divergent association between alcohol consumption and different types of stroke, with heavy drinking increasing the risk of hemorrhagic stroke. Light to moderate alcohol consumption was associated with a lower risk of ischemic stroke but no effect on hemorrhagic stroke.
Researchers have discovered that a common species of Asian tree frog (Hyla japonica) may be two separate species, with distinct evolutionary relationships between East and West Japan. The study's findings could lead to reassignment of the species' scientific name and shed light on the historical mystery surrounding its discovery.
Researchers used crowdsourced data to investigate earthquake feelings in Italy and Greece. Intermediate-depth earthquakes are often felt on the African side of the Africa-Eurasia plate boundary.
A new color-based labeling technique allows researchers to track the development and behavior of individual blood stem cells. The study reveals that these cells have a scripted set of responses and cannot make just any blood cell type.
Researchers found neuro-metabolite alterations across the brain linking stuttering to changes in brain circuits that control speech production and circuits supporting attention and emotion. Disturbances in neuronal or membrane metabolism contribute to the development of stuttering.
A study published in Avian Research has confirmed the Hen Harrier and Northern Harrier as two distinct species using genomics and molecular phylogenetics. The classification will aid national conservation efforts, particularly for the European Hen Harrier under threat from grouse hunts.
A randomized clinical trial led by Duke University School of Medicine researcher found that individual cognitive therapy relieved PTSD symptoms better and quicker than group therapy. Nearly half of participants who received one-on-one therapy improved so much they no longer carried a PTSD diagnosis, whereas almost 40 percent of those i...
Researchers found stroke rates declining in people 55 and older, but doubling in those between 35 and 39. The study also revealed that younger people are more likely to experience debilitating strokes, which can lead to long-term physical disabilities.
A new study led by Harvard T.H. Chan School of Public Health researchers found that consuming high amounts of four major saturated fatty acids increases the risk of coronary heart disease. Replacing these fats with healthier alternatives, such as whole grains and plant proteins, may reduce this risk.
A study found that people with genes for high educational achievement tend to marry and have children with similar DNA. This assortative mating increases genetic and social inequality in future generations. The researchers argue that this could lead to a cycle of increasing inequality.
Tropical Storm Otto is strengthening into a hurricane as it approaches Central America, with maximum sustained winds reaching 75 mph. The storm's center will move onshore within the hurricane warning area on Thursday and reach the Pacific coast of southern Nicaragua or northern Costa Rica early Friday.
The grant will help TGen accelerate the computer processing of transcriptomes from thousands of cells using a complex computational algorithm. This process will advance precision medicine by quickly informing doctors with the best options for attacking each individual patient's cancer.
A University of Missouri research team has developed enhanced piezoelectric sensors that can amplify signals, cut costs, and improve reading accuracy. The new technology has wide applications in aviation, detecting structural damage in buildings and bridges, and boosting the capabilities of health monitors.
The coconut crab's claws possess the strongest pinching force of any crustacean, with a maximum recorded force of 3,300 newtons, surpassing that of other crustaceans and most terrestrial animals except alligators.
A biomarker has been identified to aid in the prognosis of pediatric ependymomas, a subset of brain tumors. This discovery may lead to novel therapeutic options and more effective treatments for children with these tumors.
Researchers discovered that low-dose chemotherapy regimens can prevent the secretion of proteins by fibroblast cells surrounding tumors, reducing the likelihood of tumor recurrence. Mice with breast or pancreatic cancer treated with these regimens survived longer than those receiving high-dose chemotherapy.
Research at RIT aims to understand vitreous humor properties that result in vision impairment. The study may unlock new treatments for vision disorders and improve drug delivery and eye surgery.
MIT researchers create a new system for producing artificial muscle fibers that contract and expand like natural muscles, using ordinary nylon fiber. The approach harnesses the bending motions of nylon fibers by selectively heating one side to produce complex patterns of movement.
A decision aid significantly increased the rate of total knee replacement surgery among black patients, who were more likely to undergo surgery when informed about treatment risks and benefits. The intervention also led to a higher uptake of surgery among those willing compared to unwilling patients, women, and younger patients.
Researchers found that jet lag increases both obesity-related liver disease and liver cancer risk by disrupting the body's internal homeostasis. The study suggests that lifestyle changes leading to chronic jet lag can also increase liver cancer risk in humans.
A study by Aarhus University scientists uses three independent climate modeling methods to demonstrate that wheat yield will decline with global temperature increases. The models project a 5.7% decline in global wheat production for each 1°C temperature rise, with warmer regions expected to suffer the most.
A comprehensive community-based effort led to a significant drop in suicide rates, with a 38.3% decrease in overall deaths and attempts. The program, developed by the tribe in collaboration with Johns Hopkins researchers, tracks and triages individuals with suicidal thoughts and provides culturally tailored interventions.
Researchers at Vienna University of Technology developed a new method to create durable quantum states in nitrogen atoms and microwaves, increasing the lifetime of quantum memory by more than an order of magnitude. This breakthrough enables important quantum-technological applications with faster data processing times.
A study of over 38,000 US children found their diet quality improved between 1999 and 2012, but still lags behind, with disparities seen among racial and economic groups.
Research reveals that the grounding line of Pine Island Glacier retreated from a prominent seafloor ridge by 1945, with final ungrounding occurring in 1970. The team's findings suggest that ice-sheet retreat continued even when climate forcing weakened.
A new study found that rats with low blood alcohol levels do not consume more calories, contradicting previous assumptions. However, rats with high blood alcohol levels consume fewer calories and lose weight, suggesting a different relationship between feeding behavior and intoxication.
A substantial percentage of LASIK surgery patients experience new visual symptoms, including double images and glare, despite a decrease in overall prevalence. Researchers found that up to 43% of patients reported these new symptoms at 3 months post-op.
Researchers predict malaria elimination is achievable in southern Africa if vector control measures are implemented aggressively and mass drug campaigns focus on high-risk areas. Human movement within the region should be targeted to prevent importation of infections.