Research from UT Southwestern Medical Center found that inactivity and excess weight are strongly associated with heart failure with preserved ejection fraction, which has a poor five-year survival rate of around 30-40%. Increasing physical activity levels and reducing weight may be crucial for combating this growing disease.
New EU Water Framework Directive recommendations aim to improve monitoring, assessment, and management of water quality. The directive suggests effect-based methods instead of individual substance analysis and proposes a reversed burden of proof for data collection.
A new software tool calculates the probability of triggering manmade earthquakes from wastewater injection and oil gas production activities. The Fault Slip Potential (FSP) tool identifies at-risk faults, allowing energy companies and regulators to avoid them and implement enhanced monitoring efforts.
Researchers propose that dust traps, high-pressure regions where dust grains accumulate and avoid fragmentation, play a key role in planet formation. These spontaneous traps concentrate grains from outer disk regions, helping to form planets and addressing the long-standing problem of how pebbles join together to create planetary cores.
Researchers found that people are significantly better than chance at matching names to faces, and this effect may be due to cultural stereotypes associated with names. The study used computer algorithms to also achieve high accuracy in matching names to faces.
Researchers tracked the movement of cyborg cockroaches to understand their navigation patterns in unfamiliar territory. The study found that unguided biobots preferred to hug the wall, but randomly stimulating them increased movement time, speed, and likelihood of exploring open space.
A proposed Marine Protected Area (MPA) in the Sea of the Hebrides, Scotland, would provide essential conditions for basking sharks to forage and possibly breed. Satellite tracking data from 36 sharks showed 86% residency within the proposed area.
Studies reveal that brain activity in self-related and mentalizing regions combine unconsciously to produce a signal about an article's value, predicting its likelihood of going viral. Brain scans from a small group of people can accurately predict the virality of health articles among real New York Times readers.
A pilot study found that community-based 'Change Clubs' improved measures of heart health in Black/African American women, including a decrease in systolic blood pressure. The clubs empowered individuals to make behavioral changes through nutrition and exercise education.
A wearable brain-imaging device has been used to measure brain synchronization during conversation, providing insights into how people understand each other. The technology can be used to study various social interactions and improve communication in different environments.
The study focuses on combining SPRA technology with polypseudorotaxane (PPRX) technology to create a sustained and controllable insulin release system. Four types of PPRXs were developed, showing improved blood glucose reduction times and safety profiles.
A study published in PNAS reveals details about Apoptosis signal-regulating kinase 1 (ASK1), a signaling protein controlling cellular behavior. The research found unexpected parts of ASK1's structure that help control its activity, shedding new light on disease processes such as Parkinson's and melanoma.
A new study by Australian National University has found evidence of seawater cycling as deep as 2,900km into the Earth's mantle, raising questions about how the atmosphere and oceans formed. The research suggests alternative theories, such as icy comets or meteorites bringing water to Earth, could be plausible.
Protein misfolding may have kickstarted chemical evolution, enabling the creation of complex systems and potentially leading to the emergence of life. The study designed multi-phase dynamic chemical networks and self-propagating peptide assemblies with remarkable functions.
Researchers developed a computer method called ZeitZeiger that uses genome-wide expression data to predict a person's 'internal' time of day. The method demonstrates accurate predictions using 15 genes from across the human genome, including non-core clock genes.
Studies suggest that dogs and humans share a common type of social intelligence, which could help scientists better understand human evolution. Researchers found that dogs who excel in one social skill tend to perform well in related skills, similar to children, but not chimpanzees.
A team of researchers found that captive breeding efforts were unnecessary if hunting controls had been implemented to save the species. The study dispels the theory that the Passenger Pigeon underwent functional extinction before its actual extinction in the early 20th century.
A recent study of 74 Android mobile apps found that 89% focus on parental control, while only 11% support teen self-regulation. This approach may hinder teens' ability to develop essential online safety skills and cope with future encounters.
Activated T-cells play a crucial role in promoting heart failure after a heart attack by attacking heart muscle tissue. Targeting specific T-cell subsets at defined stages of disease may represent a better therapeutic approach to improve heart failure outcomes.
Researchers found that human-ignited wildfires accounted for 84% of all US wildfires over a 21-year period, tripling the length of the average fire season. The study highlights the importance of considering where ignitions start and how they contribute to wildfire risk.
Researchers at Rutgers and other universities created a new way to identify stem cells' state and fate, allowing for better manipulation of cells for therapy. The approach uses super-resolution microscopy to analyze epigenetic modifications, identifying changes that signal a cell's future type.
Researchers at Uppsala University found that genes frequently collaborate in large clusters or networks to regulate traits. This study highlights the importance of considering gene interactions when predicting genetic effects on individuals.
A group of researchers discovered a rare deafness-dystonia syndrome, named Siddiqi syndrome, in a family living in remote Pakistan. The condition is characterized by hearing impairment and delayed motor development, and has been linked to a single homozygous nonsense mutation in the FITM2 gene.
Researchers at Yale University and Vanderbilt University have discovered a common bacterium that can be used to sterilize male insects, potentially controlling disease-bearing mosquitoes and agricultural pests. The discovery of two genes encoded by Wolbachia bacteria can completely sterilize male fruit flies.
A new study reports improved kidney transplant success rates in children and infants over the past 53 years. The study found that young children now experience better long-term transplant success than adults, with almost 100 percent patient survival rate.
The Canadian Task Force on Preventive Health Care recommends that physicians provide brief information and advice to prevent or treat tobacco smoking in children and youth. Research shows that raising the minimum legal age for access to tobacco can significantly reduce smoking rates among young people.
Researchers at Boston University School of Medicine have found a genomic biomarker in the nasal passage that can accurately determine lung cancer likelihood. This non-invasive test may spare patients from costly and risky procedures by identifying those at low probability for having lung cancer.
Physicians should be informed about herbal medications used by heart disease patients, as their efficacy and safety are rarely proven. Discussing the pros and cons of herbal medications is crucial for effective patient counseling.
A new human monoclonal antibody has been developed to prevent cocaine from entering the brain, reducing its behavioral effects. The antibody is designed for individuals highly motivated to overcome addiction and can be given in doses that remain effective for at least 30 days.
Researchers found that observers correctly identified a person's real name based on their facial appearance even when controlling for age and ethnicity. The study suggests that self-fulfilling prophecy plays a role in matching faces with names, as people may choose hairstyles associated with stereotypes.
In a clinical trial, the ketogenic diet was found to be a safe and effective treatment option for adults with super-refractory status epilepticus (SRSE), a rare and severe form of epilepsy. The diet was shown to stop seizures in 79% of patients, with eight recovering within a week.
A McGill University and Health Canada study found that air pollution from wood burning increases the risk of heart attacks in seniors by 19% during cold seasons. The researchers suggest that tackling air pollution caused by fireplaces and woodstoves may improve public health.
A personalized strategy involving frequent CA125 blood tests and ultrasound examinations could improve the chance of detecting tumors at early stages. This approach reduced the risk of diagnosis with advanced cancer in high-risk women who chose to delay recommended preventive surgery.
Researchers from Vanderbilt University have identified specific genes that make Wolbachia, a parasitic bacterium, effective in controlling mosquito-borne diseases like dengue and Zika. The 'super-Wolbachia' gene can be used to genetically engineer insects to spread the bacteria more rapidly.
The HSC-SSP survey has released its first public dataset, containing 70 million galaxies and stars. The data reveals the statistical properties of dark matter, building on previous discoveries of nine clumps of dark matter in 2015.
A study found that teens rarely discuss online risky experiences with parents due to differing perceptions and reactions. Parents often overreact or underreact, leading teens to avoid discussing issues, which can impact their ability to navigate future online encounters.
Astronomers found that stars are ripped apart by supermassive black holes much more often than previously thought, with rates dramatically increasing during galaxy collisions. This new understanding could lead to locating and studying dim black holes in the Milky Way.
Research reveals rosiglitazone treatment increases brown fat genes in mice, reversing genetic alterations associated with obesity. The findings suggest environmental changes can reverse some genetic defects linked to type 2 diabetes.
A new study from the University of Pennsylvania School of Medicine found that the Affordable Care Act improved primary care access for Medicaid patients, increasing appointment availability from 57.9% to 63.2% between 2012 and 2016.
A recent study by Indiana University researchers found that the master gene doublesex plays a complex role in controlling the expression of physical differences between males and females. The study reveals new details about how this gene influences traits such as genitalia, brain development, and ornamentation.
Scientists found evidence of an ancient solid shell on Earth's surface using thermodynamic calculations and rock samples from Western Australia. The 'stagnant lid' model supports this theory, which contradicts the long-held assumption that plate tectonics began immediately after Earth formed.
African American women who carry a specific genetic variant of the p53 gene may have a nearly 70% increased risk of developing breast cancer before menopause. The study found an association between the polymorphism and breast cancer risk in premenopausal women, highlighting disparities in cancer research.
Researchers found that providing individuals with dietary recommendations and support led to small increases in the intake of healthy foods. Small reductions in body weight, waist circumference, and blood pressure were observed, while high-density lipoprotein cholesterol levels rose over time.
A recent analysis reveals that human-started fires account for 84% of all wildfires, tripled the length of the fire season, and dominated an area seven times greater than lightning-caused fires. Human ignitions have expanded the fire niche into areas with historically low lightning strike density.
A new study by UC Berkeley's Haas School of Business found that overnight market activity provides insight into investor sentiment at the firm level. Short-term price persistence was observed, with high and low overnight returns outperforming over the long term.
Adding universal public coverage of essential medicines to the existing system in Canada would significantly reduce financial barriers for Canadians and save $3 billion per year. The list of 117 essential medicines accounted for 44% of all prescriptions written in 2015, suggesting a feasible step towards improving access.
PSGs are recognized as trophoblast quality and embryo viability markers, with immunomodulatory and anti-inflammatory functions. The discovery of PSG receptors and interactions with integrins suggests new avenues for drug design and therapeutic intervention.
Rice University researchers simulate a nanoscale sandwich of graphene and magnesium oxide, offering unique properties for molecular sensing, catalysis, and bio-imaging. The hybrid material has tunable band gaps and optical properties, making it suitable for various applications.
Researchers found that Illinois' remaining prairie chicken populations are genetically isolated and lack sufficient habitat. Periodic human interventions, such as translocations of birds from other states, are necessary to preserve the species.
Australian scientists have discovered five key genetic regions that increase the risk of developing Macular Telangiectasia type 2 (MacTel), a degenerative eye disease leading to blindness. The findings will help researchers understand the disease and explore ways to prevent or treat its progression.
Researchers have invented a super-material that bends, shapes and focuses sound waves, pushing the boundaries of metamaterials. This innovation has the potential to revolutionize medical imaging and personal audio, allowing for precise control over sound waves.
Researchers analyzed data from thousands of online Halo and StarCraft matches to understand skill development patterns. They found that players who spaced out their activity and used consistent hotkeys habits improved most efficiently, while elite players warmed up with meaningless dummy commands to get into peak performance mode.
Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified K-homology splicing regulatory protein (KHSRP) as a regulator of the innate immune response. Depleting KHSRP improves immune signaling and reduces viral replication, suggesting that drugs inhibiting the protein may have therapeutic value.
Researchers successfully produced the first transgenic mice with a single nucleotide difference in the dystrophin and tyrosinase genes, demonstrating a new gene editing technique that can substitute one nucleotide into another without DNA deletion. This breakthrough could potentially lead to the correction of genetic defects in humans.
A recent study published in the Journal of the American College of Cardiology suggests that increased physical activity and lower body mass index (BMI) are associated with a reduced risk of heart failure with preserved ejection fraction (HFpEF), a subtype of heart failure. The research, which pooled data from three cohort studies invol...
Researchers found that involving interdisciplinary partners improved risk communication and public safety during earthquakes. Key recommendations include engaging with decision makers, developing clear warning messages, and minimizing negative impacts of inaccurate messages.
Researchers from Michigan Technological University found that fruit flies' resistance to mushroom toxins corresponds to the mammalian target of rapamycin (mTOR) pathway, regulating cell physiology and metabolism in humans. This discovery opens up new avenues for studying diseases like cancer, obesity, type 2 diabetes, depression, and n...
A study at UBC's faculty of medicine found that young people value positive interactions with peers, group therapy, and emotional support from service providers. Meanwhile, youth reported feeling pigeonholed by their mental illness and experiencing impersonal encounters with support workers.
Researchers at Northwestern University have found a molecule that stops the growth of diffuse intrinsic pontine glioma (DIPG), a fatal pediatric brain tumor. The study, published in Nature Medicine, reveals the molecule detaches proteins that enable cancer cells to grow, offering new treatment options for children under 10.
Dr. Junliang Tao receives $500,000 grant to apply burrowing strategies from nature in underground construction technologies and small-scale robots. His project aims to improve high-efficiency tunnel design and generate enthusiasm among K-12 students for STEM education.