Researchers from Gero discovered that Strehler-Mildvan correlation has no real biological basis, contradicting long-held assumptions. This finding opens up new possibilities for anti-aging therapies and life extension.
Researchers found that tropical forests provided a stable source of subsistence for human hunter-gatherers in New Guinea. Stable isotope analysis revealed prehistoric diets and lifestyles, indicating that foraging continued alongside agricultural experimentation.
A study from the University of Bristol reveals how Streptococcus gordonii binds to human cells via a 'catch-clamp' mechanism, leading to cardiovascular disease. The research provides a new target for anti-adhesive agents to combat life-threatening infections.
A new assay has been developed to detect genetic mutations in tumors, showing high sensitivity and specificity in detecting actionable genomic variants. The NCI-MATCH trial aims to evaluate tumor biopsy specimens from 6,000 patients using this technology.
Scientists have described a new species of fish-scale geckos (Geckolepis megalepis) that possess the largest scales of any gecko. These unique geckos can lose their skin at the slightest touch, making them challenging to study.
A study found that genetic differences in the spinal cord of embryos contribute to handedness, with the left side maturing faster than the right. This early difference may trigger later brain asymmetries, including language dominance in most adults.
Engineers at University of California San Diego developed a desktop diagnosis tool that detects harmful bacteria in blood samples in hours. The breakthrough uses proprietary chemistry, machine learning, and high-end imaging to identify DNA sequences from bacteria causing food-borne illnesses and pneumonia.
Amélie Juhin, a physicist and spectroscopist, has been awarded the ESRF Young Scientist of the Year 2017 prize for her experimental and theoretical studies on resonant X-ray scattering and X-ray dichroism. Her research focuses on probing electronic and magnetic properties of nanoparticles and molecular magnets.
A new method developed by Joana Goncalves-Sa's group can predict the onset of seasonal flu epidemics with accuracy, allowing health services to prepare and respond more promptly. The method integrates data from various sources, including official influenza incidence rates and Google searches, to identify changes in case numbers.
The BU College of Engineering is leading a $3.36 million project to improve connected and automated vehicles' energy efficiency by 20%. This initiative, funded by the US Department of Energy's ARPA-E NEXTCAR program, aims to reduce greenhouse gas emissions and oil consumption per mile.
Researchers at UMass Amherst have designed a novel nanoparticle-based delivery system to enhance CRISPR/Cas9's treatment potential for genetic diseases. The new delivery method achieved an editing efficiency of about 30 percent in cultured cells, with successful nuclear delivery in approximately 90 percent of cells.
Researchers found that hemocyanin, an oxygen-transporting protein, is highly expressed in Asian citrus psyllids infected with the bacterium causing citrus greening. The protein may signal an immune response to infection and could be harnessed to help control disease spread.
A recent study published in Cell Chemical Biology reveals new insights into the molecular pathway that leads to Staphylococcus aureus virulence. Researchers developed nanodiscs to observe AgrC receptor kinase activity and discovered a key regulatory hotspot, providing a starting point for designing molecules to inhibit it.
Scientists from NREL found that surface recombination significantly affects the performance of polycrystalline perovskite solar cells. The study suggests that improving surface properties could lead to more efficient devices, with potential applications in photodetectors and light-emitting diodes.
Clinical trials are now enrolling at the University of Virginia Health System to test an artificial pancreas that automatically regulates blood-sugar levels in people with type 1 diabetes. The trials will examine safety, effectiveness, and cost as well as physical and emotional health.
A study published in Cell Reports found that hydras have a network of tough protein fibers called the cytoskeleton, which acts as structural memory and guides cell alignment. This allows the hydra to regrow lost body parts with remarkable accuracy.
Researchers at the University of Montreal Hospital Research Centre have identified a new syndrome in mice with deleted Armc5 gene, characterized by adrenal gland abnormalities and immune system compromise. The study opens up new avenues for understanding and treating diseases linked to the ARMC5 gene.
A new approach to analyze brainwaves during sleep using multitaper spectral analysis provides objective and high-resolution depictions of brainwave activity. This technique offers a paradigm shift allowing clinicians to move away from subjective sleep staging and harness the wealth of objective information contained within EEG data.
Researchers at NHGRI found that iPSCs have the same mutation rate as subcloned cells, providing evidence of their stability and safety. This breakthrough enables further research and potential therapy development using patient-specific iPSCs.
A team of scientists led by Anandasankar Ray have identified Histone Deacetylase Inhibitor 6 (HDAC6) as a regulator of learning in fruit flies. The enzyme acts like a 'dimmer switch' to increase or decrease signal across synapses, and its role in healthy neurons is less understood.
A new study found that hemoglobin A1c readings are lower among individuals with sickle cell trait, suggesting a potential systemic underestimation of blood sugar control. This could lead to false sense of security for patients with diabetes.
Researchers at CWRU are testing a portable blood-adhesion monitor for sickle cell disease patients. The device aims to predict vaso-occlusive crises and help patients better manage their condition, potentially reducing physical and financial costs.
The Lomonosov Moscow State University has created an electronic depositary of living systems, featuring a unique information system with data on biological samples from various origins. The system allows for managing and sharing information about biomaterial, including descriptions of organisms and techniques for operating with them.
A new study found that high levels of air pollution can make insulin-creating cells less efficient, increasing the risk for type 2 diabetes in obese Latino children. Exposure to poor air quality during childhood increases the risk for obesity and Type 2 diabetes.
Researchers developed a method to combine anonymized mobile phone and satellite data to create high-resolution poverty maps. The study found that combining these data sources produces comparable poverty predictions with significant advantages.
A recent study published in the Journal of Applied Psychology found that employees who record over 10,900 steps per day are less likely to perpetuate abuse at home. The research suggests that sleep and exercise can be leveraged as intervention points to prevent harmful behavior.
Researchers found that enteropathogenic E. coli (EPEC) differentiates into two sub-populations, one virulent and one non-virulent, with the virulent state maintaining long-term memory. This discovery sheds light on bacterial virulence strategies and may lead to new approaches for fighting infections.
A new study by University of Maryland School Medicine researchers found adjusting kynurenic acid levels can reduce schizophrenia-like behavior in mice. Higher KYNA levels are associated with cognitive problems and reduced glutamate signaling in people with schizophrenia.
A new research provides a mechanism to detect and correct systematic errors in data and image analysis used in many areas of science and engineering. The single-pixel interior filling function (SPIFF) method can improve the accuracy of imaging systems for tracking objects on scales ranging from nanometers to astrophysical scales.
A Duke University study has found elevated selenium levels in fish from three North Carolina lakes receiving power plants' coal ash waste, contaminating aquatic ecosystems and posing health risks. The study highlights the ongoing issue of continuous contamination of aquatic resources from hundreds of coal ash ponds across the country.
A University of East Anglia study reveals that the protein ninein is crucial for normal tissue development in the human gut. The research shows how microtubule rearrangements and the assembly of new Microtubule Organising Centres facilitate cell shape formation, nutrient uptake, and ultimately prevent cancer.
Researchers have developed a hydrometallurgical method to recycle lithium batteries, recovering cobalt and lithium with reasonable efficiency. The process involves calcination, acid treatment, and leaching, resulting in useful extraction rates for the metals.
NASA scientist William Zhang has developed a technique to manufacture lightweight, high-resolution X-ray mirrors using single-crystal silicon, reducing costs and improving resolution. The new technology addresses performance goals that have long been unmet in the field of X-ray optics.
A McMaster University study reveals that short, intense stair climbing can significantly improve cardiorespiratory fitness and reduce the risk of heart disease. The research also highlights interval training as a convenient way to incorporate exercise into daily life.
A study of over 2,500 women with newly diagnosed breast cancer revealed a significant gap between the need for genetic testing and its availability. High-risk patients, particularly those from Asian backgrounds and older women, were under-tested due to lack of physician recommendation and inadequate assessment of patient risk and desire.
A new species of gecko with massive scales has been identified, having the largest scales of any gecko. The skin of this gecko is specially adapted to tearing, allowing it to escape predators easily and regenerate its scales quickly.
A study by Rosalind Franklin University of Medicine and Science identifies a specific brain circuit in the amygdala as crucial for empathy, providing hope for new treatments of social difficulties in autism. The findings suggest that targeting this region may help individuals with autism spectrum disorder develop social abilities.
University of Toronto scientists have discovered a better way to extract proteins from membranes, making it easier to study cell communication and human health/disease. Using a type of polymer, they stabilized proteins while keeping fatty molecules attached.
Researchers have made significant progress in understanding the mechanisms underlying RASopathies by studying zebrafish and fruit flies. They discovered that lower signaling levels can correspond to a RASopathy disease, challenging conventional wisdom that these disorders result from overactive RAS pathways.
A new model estimates the number of eggs a woman should freeze based on her age and family-building goals, providing data-driven guidance for women considering elective egg freezing. The model considers maternal age by individual year and incorporates the likelihood of embryo development to result in a live birth.
Researchers have identified three new uranium minerals, leesite, leószilárdite, and redcanyonite, found growing on the walls of old uranium mines in southern Utah. These minerals provide valuable insights into the chemistry and structure of uranyl compounds and their interactions with the environment.
A Stanford University study found that anyone can become a troll given the right mood and context. The research used experimentation, data analysis, and machine learning to identify simple factors that make people more likely to engage in trolling behavior.
Researchers have identified an exotic binary star system as the first white dwarf pulsar ever discovered in the universe. The star, AR Scorpii, is a rapidly spinning, burnt-out stellar remnant that emits powerful beams of radiation and particles.
Four NIH-funded research projects aim to test and refine fully automated artificial pancreas systems, replacing traditional methods for managing type 1 diabetes. The studies will evaluate safety, efficacy, user-friendliness, and cost, with the goal of bringing these life-changing devices to those who need them.
Researchers develop a scavenger scale to categorize animal traits, highlighting surprising adaptations in species like vultures, albatrosses, and cheetahs. The scale helps understand why some animals excel as scavengers while others struggle.
Scientists from UNC School of Medicine have confirmed the functions in bacterial cells of two important excision repair proteins, Mfd and UvrD, using an advanced sequencing technique. The study provides a genome-wide map of excision repair in bacteria and highlights the potential for developing novel antibiotic drugs.
A study conducted by Quebec researchers found that genetic mutations of the Armc5 gene disrupt foetal development and compromise immune responses. The protein plays a crucial role in early T-cell activation and adrenal gland biology.
Researchers estimate dinosaur age by analyzing bone structures and repair procedures, with a similar process occurring in humans. The study's findings have implications for understanding the natural life span of dinosaurs.
The Nimba toad's unique matrotrophic viviparity allows females to give live birth to fully developed juveniles after nine months. The species' isolated habitat and harsh environment are thought to have driven the evolution of this complex reproductive cycle.
Santa Fe Institute researchers investigated the lower bound of energy required for life and found that smallest species are most protein dense. As cell size increases, RNA concentrations grow, leading to a decrease in protein density, with larger cells eventually reaching an energy limit.
Scientists at Harvard and MIT have developed a new 3D printing method that can create lightweight structural materials with tunable porosity, inspired by natural cellular structures. The approach uses ceramic foam ink to produce materials with exceptional stiffness and multifunctional properties.
A rapid genotypic resistance test for colistin has been developed to detect the mobile resistance gene mcr-1, which threatens emergency antibiotics. The test demonstrated 100% sensitivity and specificity in detecting mcr-1 on plasmids.
A team of CU scientists sequenced the genome of the Australian pitcher plant, discovering genetic changes associated with its carnivorous traits. The study found similarities in digestive enzymes across different species, supporting convergent evolution theory.
Scientists have unearthed a 480-million-year-old creature named Calvapilosa, an early offshoot of the line leading to modern coat-of-mail shells or chitons. The discovery sheds light on the evolutionary history of mollusks, which includes squids, octopuses, snails, and clams.
Researchers uncovered hundreds of large, mysterious geoglyphs in Brazil's Amazon rainforest, challenging assumptions about the ecosystem. The sites were found to have been built using sustainable 'agroforestry' practices, which concentrated on economically valuable tree species.
A study from the University of Pennsylvania found that Americans' dehumanization of Muslims and Mexican immigrants is linked to increased hostility, including support for violent collective action. Dehumanizing perceptions also hinder counterterrorism efforts.
Researchers at MIT and Brigham and Women's Hospital have designed a small voltaic cell powered by acidic stomach fluids, generating enough energy to run small sensors or drug delivery devices. This innovation could offer a safer and lower-cost alternative to traditional batteries.
A compact respiratory assist device is being developed to replace traditional oxygenation methods as a bridge to transplant or recovery in children with lung failure. The device aims to allow patients mobility while awaiting a transplant, potentially leading to better post-transplant outcomes.
A team of researchers has discovered a novel approach to treating juvenile Batten disease by activating a protein called TFEB, which stimulates the cell to produce more lysosomes and degrade cellular waste. This breakthrough may lead to improved neurological symptoms in patients with the condition.
A research group at Kobe University has discovered a potential new cancer treatment that activates cancer-engulfing cells. The treatment uses an antibody to activate macrophages, which can effectively eliminate cancer cells. This discovery could lead to the development of new and more effective cancer treatments.