A study by UTHealth researchers found that a 'promiscuous' carbapenemase gene and a bacterial clone carrying an antibiotic-killing gene created the perfect storm for Colombia's antibiotic resistance epidemic. The gene spread horizontally across Gram-negative bacteria, while the clone was introduced via an infected patient from the US.
A group statement by three organizations opposes the addiction model in relation to frequent sexual behavior and pornography viewing. The statement cites a lack of scientific rigor and validity in current assessments for these concepts, as well as neglecting important cultural factors.
A team of scientists discovered that a non-pathogenic strain of E. coli helps the lining of a newborn's gut prepare for the surge of other bacteria in their lives, leading to better resistance to inflammation and damage.
Researchers at Kyoto University used a chimpanzee parent-offspring trio to estimate direct mutation rates, finding higher rates than in humans. The study also revealed a strong male-biased mutation spectrum and new structural alterations.
Researchers trained sheep to recognize celebrity faces and found they could identify their handler's face without prior training. The study suggests sheep have advanced face recognition abilities, comparable to those of humans and monkeys.
Researchers at Scripps Research Institute have discovered a compound that irreversibly stops the growth of certain aggressive, treatment-resistant tumor cells. The compound, FiVe1, blocks cell division by binding to a structural protein, vimentin, produced abundantly in mesenchymal-type cells.
A randomized clinical trial found no important differences in pain reduction between ibuprofen-acetaminophen and opioid-acetaminophen combinations after 2 hours. The study suggests that ibuprofen-acetaminophen is a reasonable alternative to opioid management of acute extremity pain, but further research is warranted.
The study reveals that climate change and insufficient international protection are endangering the North Atlantic right whale population, which has made modest gains in recent years. The lack of adequate policies in northern waterways increases the risk of ship traffic and commercial fishing gear harming the whales.
Researchers found a 10% decrease in serum zinc levels in women with prediabetes, highlighting the importance of zinc metabolism in diabetes pathogenesis. Zinc plays a crucial role in insulin synthesis and tissue susceptibility to hormones.
Tropical Depression 29W is characterized by disorganized storms with cold cloud top temperatures of minus 80 degrees Fahrenheit. Forecasters predict the depression will weaken and exit into the Andaman Sea before regaining tropical depression status.
A new study of 311 hominin fossils spanning four million years shows that stature and body mass advanced at different speeds. Hominin bodies evolved in 'pulse and stasis' fluctuations, with some lineages even shrinking.
A new technology developed by UTSA professor Samer Dessouky converts heat from paved surfaces into electricity, generating power for rural areas and potential back-up lighting in airports. This innovation uses drones to map concentrated heat sources, enabling efficient energy harvesting from hot pavements.
A Michigan State University study found that people fit into specific 'vinotypes' based on their food and beverage preferences. The researchers recommend that servers and sommeliers consider these preferences when suggesting a wine. By trusting their own palate, consumers can make informed choices about wine pairings.
A genetic inversion led to the development of mimicry in Asian swallowtail butterflies, with some species maintaining multiple forms of disguise to evade predators. The researchers found that the genetic change carried unrelated material, potentially introducing long-term disadvantages.
Researchers found that exposure to community violence is associated with increased antisocial behavior in children and adolescents, regardless of pre-existing conduct disorder. The study suggests that prevention programs can help break the cycle of violence.
Researchers found that stem cell injections improved circulation, induced gene expression changes, and reduced inflammation in diabetic mice with peripheral artery disease. The study suggests that stem cell treatment could help alleviate symptoms in severe PAD patients.
Researchers have successfully developed a method to analyze microscopic structures using incoherently scattered light, improving the analysis of small-scale biological systems. The technique has the potential to enhance imaging capabilities in fields like biology and medicine.
A new drug compound, BU10119, has been developed by scientists at the University of Bath and shown significant potential as an antidepressant in mice. The compound works by blocking kappa opioid receptors, which have anti-depressant like effects in mice, offering a new potential treatment for those who don't respond to SSRIs.
A new study by Johns Hopkins University reveals that climate change will disproportionately affect people living in crowded urban settlements in Africa. The study found that temperatures in these areas can be up to 10 degrees Fahrenheit higher than the official weather station, leading to a significant increase in heat-related deaths.
Ludwig scientists present updates on checkpoint blockade immunotherapies for advanced melanoma and phase 1 clinical trials combining PI3K-gamma inhibitors with PD-1 blockade. Researchers also discuss novel approaches to boosting radiotherapy efficacy and understanding tumor immune suppression mechanisms.
The study found that annual well-visit rates among adolescents increased from 41% to 48% after the ACA, with significant gains among minority and low-income adolescents. The ACA's requirement for coverage of preventive services without a copay led to increases in the receipt of recommended services up to age 21.
Researchers at UC Berkeley and University of Toronto have discovered lipid mediators that may halt glaucoma progression. The study found that lipoxins A4 and B4 secreted by astrocytes can stop retinal ganglion cell degeneration, offering a potential treatment for this neurodegenerative disease.
A phase 4 randomized clinical trial found that self-administered treatment for latent tuberculosis infection had a high rate of treatment completion in the United States, Spain, and Hong Kong. The findings suggest that once-weekly isoniazid and rifapentine by self-administration is noninferior to direct observation in completing treatm...
Researchers have discovered that Bryde's whales employ a unique feeding strategy involving lifting their heads to tread water, allowing prey to flow in. This 'tread-water feeding' behavior is the first recorded passive feeding method in baleen whales.
Researchers at UHN's Krembil Research Institute identified LXB4, a unique lipid that protects neurons against glaucoma in preclinical models. This discovery provides hope for devising a new strategy to protect vision in glaucoma patients and may have implications for other neurodegenerative diseases.
Researchers at Ohio State University Wexner Medical Center developed an electric bandage that can prevent bacterial biofilm infections, combat antibiotic resistance, and enable healing in infected burn wounds. The bandage generates a weak electric field without any external power supply and is already FDA-cleared.
Using ALMA's unparalleled sensitivity and resolution, the team identified eight massive dusty clouds along the center of the galaxy, each with a unique chemical signature. The clouds are thought to be aggregates of dense, warm cocoons around young stars, driving complex chemical reactions and molecule formation.
Researchers used time-resolved small-angle x-ray scattering to observe ultra-fast carbon clustering and graphite production in PBX 9502, leading to improved computer models of explosive performance. The study found a higher percentage of graphite than previously expected.
A new study found that phenylalanine reduces food intake by affecting the gut and brain, suggesting it may be used to treat or prevent obesity. The amino acid suppressed appetite by releasing hormones in the gut and activating areas of the brain involved in appetite regulation.
A new T-cell therapy approach is being tested to help fight active viral infections in children with severe immune deficiencies. The therapy uses 'viral specific' T-cells that are engineered to target three common and potentially toxic viruses: EBV, CMV, and adenovirus.
Pioneering UH researcher Chandra Mohan proposes a simpler salivary test to diagnose lupus, potentially replacing invasive blood tests. Saliva samples from people with SLE harbor antibodies and proteins that could be used as biomarkers for the disease.
INRS professors François Légaré and Federico Rosei have been elected OSA Fellows for their groundbreaking work in ultrafast molecular imaging and photonic materials development. The distinction reflects their leadership, publication record, and significant impact on optics and photonics research.
Researchers at Osaka University have developed a new catalyst to produce valuable chemicals from biomass, allowing for the creation of green raw materials for manufacturing. The catalyst enables the production of important chemicals like 2-butanol and cyclohexanol without emitting CO2.
Researchers have discovered a mechanism to develop magnetic storage media with lower energy expenditure by combining ferromagnetic and antiferromagnetic spins. Antiferromagnetic dysprosium can be toggled using short laser pulses, requiring less energy than conventional magnets.
University of Utah researchers create a new component for ultra-high-speed communications and computing using perovskite, a mineral discovered in Russia. The technology uses the terahertz spectrum to transmit data a thousand times faster than current systems.
Researchers have discovered a novel way to detoxify salty wastewater using bacteria that can generate electricity, producing hydrogen gas. The bacteria, found in deep-water brine pools, thrive in extreme conditions and have the potential to convert waste products into valuable chemical products.
A single amino acid change determines which species are vulnerable to a hereditary brain disease. The human, mouse and hamster forms of the protein have distinct three-dimensional structures at the atomic level.
A University of Kent study has found that women working as drug 'mules' are not victimized by their sex but by the illicit trade and its illegal status. The research highlights a legal bias that distorts sentencing policies, drawing attention away from the negative effects of punitive drug laws.
A study on guppy fish reveals how their immune genes evolve to resist parasites while maintaining critical function over millions of years. The research sheds light on the evolutionary dynamics of the immune system and its ability to adapt to new threats.
Neuroeconomic research investigates the neural underpinnings of the decoy effect, a marketing strategy that influences decision-making. The study reveals greater value-related activity in the left ventral striatum when the chosen option is superior to the decoy, indicating its impact on choice.
Researchers discovered that duck embryos have a high density of rapidly adapting mechanoreceptors, making them more sensitive to touch. This specialization is crucial for ducks' tactile foraging abilities, which differ from those of visual-dependent chickens.
Researchers observed a significant association between warfarin use and reduced risk of new cancers, particularly prostate, lung, breast, and colon cancers. The findings suggest that warfarin may be protective against certain types of cancer, which could have implications for anticoagulation treatment.
Researchers at KAIST developed ultra-flexible organic flash memory that can be applied to non-conventional substrates like plastics and papers. The memory technology exhibits a significantly-long projected retention rate with programming voltages on par with industrial standards.
A new study found that a mutation in the H3N2 strain of the virus is responsible for the low efficacy of last year's influenza vaccine. The team suggests investing in new technologies to produce egg-free vaccines, while emphasizing the importance of annual flu vaccination.
Researchers found a connection between abnormal glucose breakdown in the brain and the severity of Alzheimer's symptoms, with lower glycolysis rates and higher brain glucose levels correlated to more severe pathology. The study suggests that targeting glycolysis defects could lead to new treatments for Alzheimer's disease.
A review of cannabinoids' therapeutic antitumor potential highlights their ability to stimulate apoptosis in cancer cells. While promising, the evidence is currently based on limited human studies and animal models, emphasizing the need for further research.
Researchers analyzed audio clips from 143 adults to find individual language patterns related to gene expression and adversity; they discovered that these patterns better predicted adverse gene profiles than self-reported measures of anxiety and stress. This study provides a new link between spoken language and immune system regulation.
A team of researchers has found that the magma body at Long Valley was much cooler before the eruption than previously thought. The discovery challenges the traditional view of a long period with a big tank of molten rock in the crust, instead suggesting that magma is stored for a short period in a cool, crystalline state.
Green turtles breed in Cyprus and forage in Lake Bardawil, a new important feeding ground discovered using stable isotope ratios and satellite tracking. The study found that 82% of female turtles show high consistency in their isotope ratios, indicating they return to the same places.
A new study from the University of Arizona finds that people with poor social skills are at greater risk for mental and physical health issues due to increased stress and loneliness. Social skills training has shown to be effective in improving these skills.
Researchers at KAUST developed a solvent-free synthesis method for metal-sulfide nanoparticles using thiourea. The new method produces controllable composition and size of nanoparticles, with potential applications in electrical, optical, and chemical devices.
Researchers discover that cortical tension plays a key role in clustering proteins and establishing cell polarity. This force-driven mechanism allows cells to establish polarity without wasting energy by actively transporting proteins or cellular components.
The journal's Autumn 2017 issue features original research articles on mental health problems due to community violence exposure and overnight pulse oximetry for screening obstructive sleep apnea. Other topics include smoking cessation counseling accuracy and adult-onset celiac disease in primary care.
A new study published in Frontiers in Medicine found that patients who drink alcohol or smoke are more likely to experience dental filling failure. Genetic differences were also discovered to be associated with increased filling failure rates, suggesting personalized treatments could lead to improved outcomes.
PROMIS is a patient-reported outcomes measurement system that evaluates physical, psychological, and social well-being to provide information on the subjective patient experience. Lupus patients endorse PROMIS assessments as reflecting their experience with lupus, highlighting its potential utility in validating symptoms, tracking dise...
Scientists have successfully created tiny protein-based gelatin-like clumps called hydrogels inside living cells using a novel technique. This breakthrough advances research into the suspected contributions of hydrogels to human diseases, such as neurodegenerative disorders.
Scientists used remote acoustic monitoring to track bird activity on Okinawa, finding more animal sounds in less developed areas. The study also confirmed that human-caused noise can be disruptive for birds.
A new study by NYU Steinhardt School of Culture, Education, and Human Development found that afterschool programs with positive, responsive, and organized environments can have significant academic benefits for students. The study examined the role of afterschool classroom environment in terms of academic outcomes for youth with and wi...
Researchers at Scripps Research Institute identify diamidophosphate (DAP) as a potential 'missing link' in chemistry that led to the emergence of life. DAP can phosphorylate key ingredients in early life forms, leading to the formation of primitive cells and potentially kick-starting life on Earth.
Researchers found that neurons in the brain's 'reward center' fired more rapidly in response to alcohol when estrogen levels were high. This increased sensitivity may play a role in the development of addiction in women, particularly during certain stages of their menstrual cycle.