An international team, including SD Mines researchers, has found the first evidence of a source of high-energy cosmic neutrinos detected by IceCube. The blazar TXS 0506+056 is confirmed as the source, providing a pathway for scientists to follow back to the source.
A Portland State University professor has received a $3.3 million federal grant to study the impact of an early-learning program aimed at improving children's readiness for kindergarten and later grades. The MindUP program, designed by actress Goldie Hawn's foundation, focuses on developing social-emotional and self-regulation skills.
Researchers are studying how material-water interfaces impact water quality sensors, filtration membranes, and pipes. New sorbents with high reusability and specificity are being designed to address global clean water accessibility challenges.
TGen has opened a DIPG tissue donation portal to advance research into the rare and incurable disease, which affects about 350 children in the US each year. The portal aims to accelerate the development of new treatments through collaboration with researchers and families affected by the disease.
A study of 2,587 Los Angeles County high school students found that frequent use of digital media was associated with a higher likelihood of ADHD symptoms occurring over a 24-month period. The researchers suggest that more research is needed to determine if the association is causal.
Researchers at the University of Pennsylvania and Syracuse University have developed a compound that effectively controls hyperglycemia in animal trials without causing nausea and vomiting. The modified compound is less absorbed into brain regions that trigger these side effects, leading to vastly improved tolerance.
A cluster-randomized trial in Western Kenya found that coupling free diagnostic tests with discounts on artemisinin combination therapy (ACT) boosted testing rates and improved the rational use of ACTs. The intervention increased malaria diagnostic testing by 50.5% and reduced misuse of antimalarial drugs.
A survey of 6,641 people found that nearly 40% had a fictional first memory, with middle-aged and older adults more likely to claim such memories. Researchers suggest these may be based on remembered fragments of early experience and facts about infancy.
Researchers analyzed over 51 million tweets to find that people are more likely to interact with those geographically near, even in the age of digital technologies. This study challenges the idea that geography is dead and instead highlights the importance of distance in human interactions.
A study published in eLife found that deleting a single gene from a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice. The researchers discovered that this genetic change altered the levels of certain bile acids, leading to a preference for metabolizing fats rather than carbohydrates.
Researchers investigating genetic and environmental factors contributing to aggressive prostate cancer in African-American men, a population with a 15% lifetime risk compared to 10% for white men.
The study found a significant increase in secondary imaging interpretations across various modalities and body regions, driven by high-volume service families. Denial rates for these services were uniformly low, below 25%, contradicting conventional wisdom.
A new species of dogfish shark, Genie's Dogfish (Squalus clarkae), has been discovered in the Gulf of Mexico and western Atlantic Ocean. The species was identified through genetic testing and morphology, and is named after Eugenie Clark, a pioneering female shark biologist.
Researchers developed a systematic approach to spot stevia blends with outstanding taste performance, revealing glycoside mixes that deliver superior taste and significant sugar reduction. The study used extensive sensory studies and mathematical modeling techniques to identify synergistic blends that outperform pure glycosides.
Researchers found that highly unequal agricultural societies have fewer instances of polygyny due to the high concentration of wealth. The model tested on diverse societies revealed that wealthy individuals with multiple wives often have fewer children than those with similar wealth divided between two wives.
The new assay enables simultaneous measurement of tirabrutinib bound and total BTK levels, reducing sample requirements. It uses full-length purified recombinant human BTK protein and PBMCs derived from healthy volunteers and patients with CLL, demonstrating its utility for pharmacodynamic assessments.
Researchers created a new cost-effective instrument combining mass spectrometry and thermal desorption to study uracil's molecular dynamics. The technique provides insights into mechanistic principles that could inform better medicines and optimize photo-dynamic therapies.
A new study found that white mass shooters are 95% more likely to be described as mentally ill in media coverage compared to black shooters. The research analyzed 219 mass shootings and found that whites were often framed as sympathetic characters, while black shooters were portrayed as dangerous and a menace to society.
A recent study found that a substantial majority of older adults with probable dementia in the US are either undiagnosed or unaware of their diagnosis. Factors such as lower education levels, attending medical visits alone, and fewer functional impairments were linked to this lack of awareness.
A study found that variations of a single gene in pigeons are associated with diverse feather patterns and unexpected links to human vision defects. The gene, Norrie Disease Protein, is well-studied in humans but has different effects on pigs, causing only pigmentation changes.
Scientists have discovered a set of powerful broadly neutralizing antibodies in the blood of Ebola survivors, providing substantial protection against disease caused by three Ebola virus species. The researchers hope that these antibodies will serve as promising candidates for further development as therapeutic molecules.
A $1.54 million NIH grant will support research on modifying troponin T to improve cardiac function in heart failure. The study aims to develop a new approach for treating this condition by targeting the physiological modification of cardiac troponin T.
A study by Johns Hopkins Bloomberg School of Public Health suggests that males recover more quickly from influenza infections because they produce more of the key lung-healing protein, amphiregulin. The research found that females have slower tissue-repair during recovery due to relatively low production of amphiregulin.
A new study reveals that black children are more likely to be suspended or expelled from elementary school due to factors such as school characteristics rather than behavior problems. The researchers found that about 40% of African-American boys were suspended or expelled, compared to 8% of white boys or from other ethnic groups.
Researchers established zebrafish mutants of four PIH-protein genes and found specific dynein subtypes are required for each PIH protein's function. The study demonstrates distinct roles of PIH proteins in axonemal dynein assembly, which may explain cilia motility defects.
A new study published in eLife reveals that roundworms, specifically Caenorhabditis elegans, use nitric oxide gas as a sensory cue to avoid the pathogenic bacteria Pseudomonas aeruginosa. The protein thioredoxin plays a crucial role in regulating the temporal dynamics of the worm's response to the gas.
A team of researchers found that the sun's rotational cycle influences lightning activity in Japan, with peaks every 24 to 31 days. The solar cycle affects the level of solar activity, which amplifies the rhythm of lightning activity.
New research reveals how cannabis triggers hunger hormones and changes brain activity to stimulate appetite. The study's findings could lead to targeted treatments for severe appetite loss in various chronic illnesses, improving quality of life and recovery.
Professor Stephen Robertson's research team identified the cause of Recessive Spondylocarpotarsal Synostosis Syndrome, a condition resulting in bone fusion. Genome sequencing revealed multiple genes implicated in the disorder, offering diagnostic and therapeutic options.
Representative Walter J. Leger III will receive the ESA Regional Policy Award for his commitment to science-based restoration of the Gulf Coast. He has championed coastal restoration and preservation, and works to ensure proper use of funds intended for coastal protection and restoration.
The Society for Industrial and Applied Mathematics (SIAM) has awarded 16 distinguished mathematicians for their outstanding research and contributions to the field of applied mathematics and computational science. The recipients were honored at the SIAM Annual Meeting Prizes and Awards Luncheon in Portland, Oregon.
The Pediatric NEXUS Head Computed Tomography Decision Instrument (DI) reliably guides blunt trauma imaging decisions and may decrease head CT imaging in low-risk pediatric populations. The study found that the decision instrument could significantly reduce head CT utilization by up to 34%.
A new USC Dornsife-led psychology study shows that conservatives tend to feel their lives have meaning or purpose. The results suggest a unique aspect of political conservatism provides people with this sense. Other factors like personal characteristics and situational influences also play a role.
Scientists at UNC Chapel Hill developed a new technique to selectively send specific colors of light over long distances using nanoscale wires. This breakthrough enables the creation of more controlled and effective optical computing technology, promising faster and more efficient computers.
Researchers have developed an algorithm that predicts which individuals with depression are most likely to benefit from antidepressant medications. The study found that approximately one-third of participants responded meaningfully to medication, while the remaining two-thirds showed no significant improvement.
Research by University of Bath finds that modern slavery victims are not always worked to exhaustion, but instead given little or no work for weeks, accumulating large debts. This 'coerced consumption' drives them deeper into financial dependence and exploitation.
NASA's PACE mission will use Delay/Disruption Tolerant Networking (DTN) to demonstrate the first key opportunity of this revolutionary capability. DTN enables information to be sent through space and ground networks without a continuous path, making it ideal for remote locations with limited network connectivity.
Yale Cancer Center scientists have found that rare inherited cancer syndromes are driven by a breakdown in how cells repair their DNA. They suggest using PARP inhibitors to treat these conditions.
Lehigh University researchers aim to block specific virus entry while preserving normal cellular processes, which is a principal difficulty in designing therapies against viruses. The Ebola virus infects healthy cells by disguising itself as debris, prompting the need for accurate understanding of virus uptake processes.
Researchers identified a model for reducing binge drinking in college students by convincing them of the immediate benefits of responsible drinking. Women and non-white students were more receptive to this approach, with higher willingness to initiate and sustain responsible drinking habits.
A new study emphasizes the importance of behavioral policies in encouraging the adoption of alternative-fuel vehicles, citing consumer preferences and climate policies as key factors. The research suggests that a combination of policies can increase the market share of low-carbon vehicles to over 25% by 2050.
A Rochester Institute of Technology researcher has developed a new solar sailing technology using diffractive metafilm materials that could propel spacecraft more efficiently and reduce overheating. The new material can steer reflected or transmitted photons for near-Earth, interplanetary, and interstellar space travel.
A new study from Ohio State University found that girls' ability to regulate their behavior is associated with a higher risk of obesity, while boys' high self-regulation reduces the risk. The study suggests that interventions aimed at improving self-regulation may not be effective for all genders.
A consortium of nine labs across the US and Netherlands standardized RNA sequencing methods to improve consistency and accuracy in liquid biopsies. The study found that different methods produced varying results, highlighting the need for standardized protocols to facilitate reproducible data and progress in the field.
Scientists have discovered that CRISPR/Cas9 gene editing can cause extensive mutations, including DNA deletions and insertions, leading to major implications for its use in gene therapies. The study highlights the need for specific testing and caution when using CRISPR/Cas9 in therapeutic applications.
A study by ISGlobal reveals significant discrepancies in global tuberculosis death estimates between the World Health Organisation (WHO) and the Institute for Health Metrics and Evaluation (IHME), primarily due to differences in methodology and data sources. The researchers identify a dozen countries with notable variations, emphasizin...
Researchers found that stimuli in the environment can influence what we think about and activate subconscious 'sets' that override conscious intentions. This challenge traditional views of a private conscious mind, suggesting it may be more permeable than thought.
Researchers found that lysophosphatidic acid levels increase after traumatic brain injury, particularly in areas associated with cell death and axonal injury. Elevated LPA may serve as a biomarker for TBI through blood testing, providing a prognostic indicator of injury and outcome.
New research on the Neohelice granulata crab reveals that it combines visual information from both eyes to track moving targets. This complex binocular processing may be essential for capturing prey and interacting with other crabs.
The publication demonstrates the company's technology induces efficient and precise in vivo gene editing using homologous recombination, a natural DNA correction pathway. This early academic research translated into a scalable process for genetic medicines development.
A study found that participants who resisted alcohol-induced impairment were more resilient to sleep deprivation, suggesting a correlation between adenosine A1 receptor changes and cognitive resilience.
A new study published in Nature Medicine found that fetal gene therapy can prevent and cure neonatal lethal neurodegenerative diseases in humans in utero. The therapy was tested on mice with Gaucher disease and showed promising results, including improved brain degeneration and increased survival time. Researchers believe this approach...
Patients with persistent facial pain incur significant costs, including £650 per year out-of-pocket expenses. An electronic referral system using a Graded Chronic Pain Scale could improve quality of life and reduce costs to employers by providing a structured care pathway.
A new study finds that email incivility has a ripple effect on households, causing stress and withdrawal among employees and their domestic partners. The negative effects of rude emails extend beyond the workplace and can lead to physical symptoms and emotional strain.
A new study published in the Journal of Neuromuscular Diseases found that early treatment with nusinersen can improve motor function in babies with SMA type 1. The research suggests that early diagnosis and initiation of treatment are crucial for patients with infantile-onset spinal muscular atrophy.
Researchers found a significant association between wildfire activity and elevated fine particulate matter (PM2.5) levels in the northwestern United States. The study, published in Proceedings of the National Academy of Sciences, suggests that increased wildfires may offset reductions in anthropogenic PM2.5 levels.
A study found that protecting tropical forest carbon stocks is ineffective for biodiversity in ecologically valuable forests. In fact, up to 77% of species protected through carbon conservation were not saved in these areas. The researchers suggest focusing on both carbon and biodiversity conservation efforts to safeguard unique wildlife.
A national population-based cohort study found that weight loss surgery reduced the risk of hormone-related cancers (breast, endometrial, or prostate cancer) by 77%. However, gastric bypass was associated with a greater than twofold increased risk of colorectal cancer.
Researchers from MSU found evidence of CO<sub>2</sub>-rich fluids in graphite samples and fluid inclusions in quartz, suggesting the rocks formed through interaction with the Kaapvaal Craton. This discovery provides insights into the geological history of the Limpopo Complex and its potential for ore prospecting.
Researchers at TU Wien have rethought the distribution of T cell receptors, suggesting a random arrangement that enables rapid immune reactions. This new understanding may lead to improved medical treatments and better comprehension of the initial stages of identifying pathogens.