Breakthrough in understanding Warsaw breakage syndrome
A breakthrough discovery reveals that the DDX11 helicase enzyme plays a vital role in DNA repair and serves as a backup to the Fanconi Anemia pathway. This finding has significant implications for understanding genomic stability and disorders associated with DNA repair deficiency, including cancer and developmental disorders.
SourceTokyo Metropolitan University·JournalProceedings of the National Academy of Sciences·DateSep 1, 2018