2023 EPS Europhysics Prize
The prize recognizes the duo's discovery that topology can classify compounds, similar to the Periodic Table. They have predicted and designed thousands of new topological compounds and experimented with many of these.
Science News for July 3, 2023
Atoh1 is critical to establish the diversity of pontine nuclei neurons
Researchers discovered six distinct neuronal lineages in pons region of brainstem, critical to motor movements. Partial loss of Atoh1 gene function affects specific subtypes of pontine nuclei neurons, leading to differences in vulnerability.
Everything in balance? How a molecular switch controls lipid metabolism
A molecular switch called Arf1 controls the storage or conversion of lipids into energy in cells. When energy is needed, Arf1 allows lipids to enter mitochondria, where they are converted into ATP.
Three things to know: Climate change’s impact on extreme-weather events
Researchers investigated climate change's effect on extreme weather events like wildfires and found a 'worst-case' scenario could lead to significant increases in intensity, frequency, and duration. The study emphasizes the need for proactive measures, including emission reductions and adaptation strategies, to build resilience.
SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateJul 3, 2023
Maternal mortality in the U.S. more than doubled between 1999 and 2019
A new study found that maternal mortality rates have worsened from 1999 to 2019, with the highest rates seen in Black women. The study used data from 1999 to 2019 and found significant disparities in maternal mortality rates across states and racial/ethnic groups.
Hedging strategy for coral restoration balances diversity, ecosystem benefits
A new hedging strategy for coral restoration balances species diversity and ecosystem benefits by selecting key species that maintain critical functions. The approach considers a range of local species and ecological characteristics to ensure the most effective restoration outcomes.
SourceUniversity of Hawaii at Manoa·JournalJournal of Applied Ecology·TypeData/statistical analysis·DateJul 3, 2023
Perceiving the smell of lemon, geranium or eucalyptus: a study on the electrical signals behind human olfaction
Researchers from SISSA have measured the electrical activity of cells in human olfactory epithelium, revealing a complex communication process between neurons and support cells. The study also explores reactions to various odorant molecules and sets the stage for investigating anomalies related to COVID-19's impact on smell.
SourceScuola Internazionale Superiore di Studi Avanzati·JournaliScience·TypeExperimental study·DateJul 3, 2023
Supportive communities can help increase breastfeeding rates for moms, MU study finds
A new study from the University of Missouri-Columbia found that supportive communities and education about breastfeeding health benefits can boost breastfeeding rates, particularly in rural areas where it is less common. The study also showed that reduced stigma surrounding breastfeeding occurred with increased community exposure.
Synthesis of a glycan hairpin
A collaborative work led by CIC bioGUNE successfully designed and synthesized a carbohydrate sequence capable of folding into a stable secondary structure. The glycans were generated using an automated synthesizer, which rapidly prepared the scaffold, revealing potential new properties for sugars in medicine, catalysis, or nanotechnology.
COVID-19 booster vaccine doses strengthen immunity in blood cancer patients
Research by the University of Southampton found that repeated COVID-19 vaccine doses increase immune response in blood cancer patients, generating higher-quality antibodies. Booster vaccinations are essential for maintaining protection against COVID-19 in immunocompromised individuals.
SourceUniversity of Southampton·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateJul 3, 2023
A UCLA-led team has received a $925,000 CDC grant to track mpox outbreaks across the US
A UCLA-led team is tracking mpox outbreaks across the US with a new surveillance project called CRASHED. The research aims to identify cases beyond high-risk groups and determine if mpox remains rare or resurges more broadly.
Quasar ‘clocks’ show Universe was five times slower soon after the Big Bang
Researchers used quasar data to analyze time dilation in the early universe, confirming that it was running at five times slower. By observing nearly 200 quasars, scientists were able to standardize their 'ticking' and chart the expansion of space.
New brain circuit for epilepsy uncovered
A new study by investigators from the Brigham and Women’s Hospital found that lesions associated with epilepsy are connected to a common brain network, suggesting the brain connections disrupted by the lesions are key. This discovery may have clinical implications for predicting epilepsy risk and targeting treatments.
Satellite-based disaster early warning systems can improve evacuation measures in remote Asian communities
Researchers assessed the effectiveness of current early warning systems and presented a case for utilizing satellite-based QZSS-EWS to improve these systems. Implementing such technology alone is insufficient, requiring policymakers to undertake subsequent policy and practical actions to upgrade these systems.
SourceMaximum Academic Press·JournalEmergency Management Science and Technology·TypeExperimental study·DateJul 3, 2023
AI and CRISPR precisely control gene expression
A new study by researchers at NYU and the New York Genome Center combines deep learning with CRISPR screens to control human gene expression. The model predicts on- and off-target activity of RNA-targeting CRISPRs, enabling precise gene controls for developing new therapies.
AI and CRISPR precisely control gene expression
Researchers develop predictive model to control gene expression with high accuracy, enabling precise modulation of gene dosage. The AI-powered tool uses deep learning to predict on- and off-target activity of RNA-targeting CRISPRs, holding promise for treating viral infections and developing new therapies.
SourceColumbia University School of Engineering and Applied Science·JournalNature Biotechnology·DateJul 3, 2023
Older frail patients have a 1-in-3 chance of surviving CPR during surgery
A recent study found that around one in three older frail patients survive surgical CPR, with significant association between frailty and mortality. Frail patients were more likely to die from cardiac arrests during non-emergency procedures than non-frail individuals.
Sheep and cattle-killing disease carriers never take a break
Researchers found that biting midges responsible for transmitting the virus are active on warmest days throughout the winter, contrary to previous theories. The discovery suggests that bluetongue virus transmission is likely ongoing year-round, with potential economic impacts for cattle farming.
Estimating the long-term effects of whale shark feeding practices
Researchers found daily movements and metabolic rate increased by up to 55% due to tourism, with a suggested daily food intake of 220kg to offset high activity. Feeding whale sharks may have negative effects on movement and activity if not managed properly.
First direct visualization of a zero-field pair density wave
Scientists have observed the direct visualization of a zero-field pair density wave in an iron-based superconductor, EuRbFe4As4, without a magnetic field. This discovery paves the way for further research into room-temperature superconductivity and its potential applications.
Understanding the regulation of apicoplast gene expression in the malaria parasite
Scientists at Tokyo Institute of Technology identified ApSigma, a nuclear-encoded apicoplast RNA polymerase σ subunit that coordinates gene expression with the life cycle of Plasmodium falciparum and host circadian rhythm. Melatonin is shown to increase apicoplast transcription and expression of the apSig gene.
SourceTokyo Institute of Technology·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJul 3, 2023
Study shows Kant’s influence on Georges Canguilhem, who anticipated concepts current in medicine today
French philosopher Georges Canguilhem was influenced by Immanuel Kant's ideas on 'technique', 'technical activity' and 'practice', which shaped his conception of medicine. Canguilhem prioritized the egalitarian principles symbolized by the French Republic's motto, emphasizing the importance of social well-being in health.
Water storage capacity in oceanic crust slabs increases with age, researchers find
Scientists have discovered that older subduction zones store more water than younger ones. This discovery has significant implications for our understanding of tectonic settings and mass recycling.
Researchers identify a new mechanism, cancer hijacks enzyme substrate motif mutations
Researchers identified a new mechanism by which cancer hijacks enzyme substrate motif mutations, enabling tumor growth and therapy resistance. The study found that colorectal cancer hijacks BUD13 mutations to inactivate a key tumor suppressor, Fbw7.
SourceUniversity of North Carolina Health Care·JournalJournal of Experimental Medicine·DateJul 3, 2023
Researchers develop tool that could improve liquid biopsy
A UCLA research team has developed a new method called cfSort to accurately quantify tissue-derived cell-free DNA in liquid biopsies. The approach identifies unique methylation patterns for each tissue, enabling accurate diagnosis and monitoring of diseases.
SourceUniversity of California - Los Angeles Health Sciences·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJul 3, 2023
Planting seeds: FSU researchers dig into how chemical gardens grow
Researchers from Florida State University have developed a model that explains how chemical gardens grow upward, form different shapes, and undergo changes in material properties. The study provides insights into the universality of formation patterns and validates observations of self-healing capabilities.
SourceFlorida State University·JournalProceedings of the National Academy of Sciences·DateJul 3, 2023
Quantum physics secures digital payments
Researchers at the University of Vienna have developed an unconditionally secure system for digital payments using quantum mechanics. The new protocol, which utilizes single photons, ensures that transactions cannot be duplicated or diverted by malicious parties.
A novel hydrogel may be a beacon of hope for infertility and fertility challenges
A novel hydrogel has been developed to induce endometrial regeneration and elucidate its mechanism, offering new hope for patients struggling with infertility. The gel, made from uterus-derived decellularized extracellular matrix, successfully regenerated the endometrium in mice, creating a favorable environment for embryo implantation.
SourcePohang University of Science & Technology (POSTECH)·JournalAdvanced Functional Materials·DateJul 3, 2023
The looming 840,000 tonne waste problem that isn’t single-use plastics
A new recycling method for carbon and glass fibre composites has been developed by researchers at the University of Sydney, which can reduce energy use by 70% and preserve mechanical properties. The approach ensures increased material recovery and improved energy efficiency compared to previous methods.
SourceUniversity of Sydney·JournalComposites Part B Engineering·TypeExperimental study·DateJul 3, 2023
Sports Ethics and Integrity: New EU program sponsors doctoral candidates from all over the world
The European Union's Doctoral Training Network in Sport Ethics and Integrity aims to educate a new generation of experts who can detect and prevent threats to sports integrity. The program will engage research on aspects of integrity in sports at the doctoral level, with a focus on doping, match-fixing, data protection, and abuse.
ERβ as a mediator of estrogen signaling in inflammatory breast cancer
Inflammatory breast cancer is a rare and aggressive form of breast cancer with poor outcomes. Research highlights the role of ERβ as a mediator of estrogen signaling, demonstrating its tumor suppressive effects in preclinical models. ERβ's antimetastatic activity may hold promise for improving treatment options for IBC.
Global, regional, and national epidemiology of diabetes in children
The study highlights the increasing global burden of childhood diabetes, with rising deaths and disability-adjusted life-years. Improved understanding of diabetes epidemiology in children is crucial for prevention and control efforts.
New approaches against the consequences of birth asphyxia
Researchers tested 25 active agents in a small animal model and found seven substances more effective than standard therapy. Caffeine proved to be the most effective in reducing brain damage, with anti-inflammatory and neuroprotective properties.
SourceDZNE - German Center for Neurodegenerative Diseases·JournalScientific Reports·TypeExperimental study·DateJul 3, 2023
Vaginal suppository containing lactobacilli can prevent recurrent cystitis in women
A study published in Frontiers in Microbiology found that administering vaginal suppositories with Lactobacillus crispatus can restore a healthy balance of vaginal microbiota and prevent recurrent cystitis. The researchers discovered that postmenopausal women with RC had significantly different bacterial communities compared to those w...
Brief admissions by self-referral can help adolescents with self-harming or suicidal behaviour
A study led by Lund University researchers found that brief admissions by self-referral can effectively reduce the need for acute visits, admissions, and longer treatment periods among adolescents with borderline personality disorder. The method empowers patients to determine when they need treatment, enhancing their autonomy and sense...
Virtual exploration of chemical reactions
Researchers from Hokkaido University developed a centralized, interactive platform to explore and analyze chemical reaction pathways. The Searching Chemical Action and Network (SCAN) platform utilizes AFIR calculations to provide an interactive reaction pathway map that can be searched and viewed.
SourceHokkaido University·JournalDigital Discovery·TypeComputational simulation/modeling·DateJul 3, 2023
Study suggests resistance training can prevent or delay Alzheimer’s disease
Researchers found that four weeks of resistance training with weights reversed behavioral and physical alterations characteristic of the disease in mice. The study's results suggest that physical activity can be an effective strategy to avoid or delay the appearance of symptoms of sporadic Alzheimer’s, which may be associated with aging.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalFrontiers in Neuroscience·DateJul 3, 2023
Redox-based transistor as a reservoir system for neuromorphic computing
Researchers develop an ionic device utilizing redox reactions to achieve a high number of reservoir states, enabling efficient complex nonlinear operations. The device demonstrated remarkable performance in solving second-order nonlinear dynamic equations and predicting future values with low mean square prediction error.
SourceTokyo University of Science·JournalAdvanced Intelligent Systems·TypeExperimental study·DateJul 3, 2023
Obesity should be renamed to improve treatment and prevention
A new study suggests renaming 'obesity' to 'adiposity-based chronic disease' to clarify the nature of the complex condition. This could help address inequities in treatment and reduce stigma associated with body size.
Kabbani to receive funding for study of mitochondrial targeting and regulation
Kabbani's research aims to identify mitochondrial responses to plant-derived compounds and create an iterative dataset for biomarker discovery and drug design. The study is part of a larger effort to understand the role of mitochondrial regulation in human diseases and develop new treatments.
Amazon dolphins at risk from fishing, dams and dredging
A new study reveals that Amazon river dolphins are under threat from fishing, proposed dams, and dredging, with their home ranges spanning over 50km. The dolphins were found to be on average 252km from the nearest proposed dam and 125km from the nearest dredging site.
Limiting loss in leaky fibers
Researchers have figured out why some air-filled fibre designs work so much more efficiently than others. Dr Leah Murphy and Emeritus Professor David Bird from the University of Bath developed a theoretical understanding of the relationship between fibre structure and leakage loss.
Trends in state-level maternal mortality by racial and ethnic group
A study of US state-level maternal mortality from 1999 to 2019 found increased risk among American Indian, Alaska Native, and Black individuals. The study highlights persistent disparities in maternal health care, with limited impact on prevention efforts.
Scientists discover Rydberg Moiré excitons
Researchers have discovered Rydberg moiré excitons in WSe2 monolayer semiconductor adjacent to graphene, exhibiting multiple energy splittings and a pronounced red shift. The discovery holds promise for applications in sensing and quantum optics due to the strong interactions with the surroundings.
New study reveals abrupt shift in tropical Pacific climate during Little Ice Age
A recent study analyzed sediment cores from a Philippine lake, revealing a 200-year period of drought in the western Pacific during the Little Ice Age. The researchers attribute this change to zonal gradients in sea surface temperature, which highlights the importance of understanding past climate dynamics for predicting future climate...
SourceGFZ GeoForschungsZentrum Potsdam, Helmholtz Centre·JournalCommunications Earth & Environment·TypeExperimental study·DateJul 3, 2023
Serious monkey business: Chimpanzee heart check via digital camera
A team of researchers from the University of South Australia used a contact-free technique to extract cardiac signals from chimpanzees by filming subtle movements in their face or thorax. The study found that chimpanzees show similar responses to human babies when experiencing fear, excitement, or joy, and that nature scenes can calm t...
SourceUniversity of South Australia·JournalBehavior Research Methods·TypeData/statistical analysis·DateJul 3, 2023
Counting Africa's largest bat colony
A new method developed by the Max Planck Institute of Animal Behavior has counted Africa's largest bat colony using GoPro cameras and artificial intelligence. The estimate puts the colony at between 750,000 and 1,000,000 bats, making it the largest for bats by biomass anywhere in the world.
Associations of food insecurity and memory function among middle to older–age adults
A study published in JAMA Network Open found a significant association between food insecurity and accelerated memory decline in middle to older-age individuals. The researchers suggest that exposure to food insecurity in older age may have long-term negative effects on cognitive function.
Researchers propose new method to measure cosmic expansion
A team of researchers has proposed a new method to measure the cosmic expansion by studying gravitational waves. The method involves counting repeat black hole mergers and analyzing the delay between them, allowing for accurate measurement of the universe's expansion rate.
Sylvester Research: Remnants of ancient retrovirus may drive aggressiveness and resilience of malignant brain cancers
Researchers at Sylvester Comprehensive Cancer Center found that the ancient retrovirus HML-2 alters stem cell programming by activating a gene-regulating protein called OCT4, contributing to glioblastoma formation and aggressiveness.
Cigarette smoke and HPV have synergistic effects on cells, heightening the risk of head and neck cancer
Researchers found that cigarette smoke and HPV interact to heighten the risk of head and neck cancer by increasing oxidative stress and DNA damage. The study's results pave the way for novel strategies in prevention and treatment.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Journal of Molecular Sciences·DateJul 3, 2023
A better way to create space
Researchers at KAUST have developed a simple technique to create highly porous organic polymers, known as poly(aryl thioether), for applications in photocatalysis and optoelectronics. The material exhibits high surface area and tunable porosity, making it suitable for removing organic micropollutants and toxic mercury ions from water.
SourceKing Abdullah University of Science & Technology (KAUST)·JournalAngewandte Chemie International Edition·DateJul 3, 2023
New role for taste receptors
Researchers found that bitter taste receptors can detect and respond to bile acids, which are produced in the liver and play a crucial role in fat digestion. The discovery suggests that bitter taste receptors may have evolved not only to detect food toxins but also to sense endogenous substances.
SourceLeibniz-Institut für Lebensmittel-Systembiologie an der TU München·JournalCommunications Biology·TypeExperimental study·DateJul 3, 2023
Scientists propose new strategy for modern sails to help shipping sector meet its carbon reduction goals
Researchers have identified an operational strategy that can reduce shipping emissions by up to a quarter by combining modern sail technology with efficient routing systems. The study found that this approach can provide greater assurances of carbon savings by mitigating the impact of unpredictable weather patterns.
Chemists discover why photosynthetic light-harvesting is so efficient
Researchers found that disordered organization of proteins boosts energy transfer efficiency, allowing nearly every photon to generate an electron. This finding could lead to better understanding of photosynthesis and potential applications in artificial systems.
SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJul 3, 2023
Base editing shows potential superiority for curing sickle cell disease
Researchers use base editing technology to restart fetal hemoglobin expression in SCD patient cells, achieving higher and more stable levels than other genome editing technologies. The approach has potential as a 'one-size-fits-all' treatment for all mutations that cause SCD and beta-thalassemia.
Experimental constraints on the oxidation state of early magma on the Earth
Research investigates early magma ocean and its impact on the Earth's surface environment, shedding light on planetary interior and surface interactions. The study suggests that metallic iron from late-accreting materials may have reduced the upper mantle's oxidation state.
A spatiotemporal intelligent framework and experimental platform for urban digital twins
This paper proposes an FSSiamese target tracking algorithm based on Digital Twins network, building a GeoAI experimental platform to analyze urban video data. The proposed framework enhances geospatial perception, understanding, and decision-making in urban Digital Twins.
SourceBeijing Zhongke Journal Publising Co. Ltd.·JournalVirtual Reality & Intelligent Hardware·DateJul 3, 2023
‘Workplace AI revolution isn’t happening yet,’ survey shows
Only 36% of UK employers have invested in AI-enabled technologies like industrial robots and chatbots over the past five years, new research suggests. The survey highlights a growing skills problem, with less than 10% anticipating digital skills training investment in the coming years.
Cutting edge transistors for semiconductors of the future
Researchers at Lund University have created ferroelectric 'grains' that control tunnel junctions in transistors, allowing for individual-level control and optimization of material properties. This breakthrough enables the development of new circuit architectures for neuromorphic computing and energy-efficient semiconductors.
Trends in mortality from poisonings, firearms, and all other injuries by intent
Death rates due to unintentional poisonings and firearm homicides rose substantially in the US from 1999 to 2020, highlighting a pressing public health concern. The study's findings underscore the urgent need for targeted interventions to address this alarming trend.
State medical cannabis laws not associated with reduced use of opioid or nonopioid pain treatments
A study of commercially insured adults with chronic noncancer pain found that state medical cannabis laws did not lead to a reduction in the use of opioid or nonopioid pain treatments. The researchers also suggested slow implementation and reluctance among healthcare leaders may have contributed to these findings.
SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateJul 3, 2023
Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo
This study demonstrates the potential of cell therapy using genome-edited iPS cells secreting therapeutic molecules, such as mNAGA, to supply GLA activity in vivo. Transplantation of these cells improved GLA activity in the liver, but not in other organs, and future enhancements are possible through genome editing.
SourceTokyo Metropolitan Institute of Medical Science·JournalCell Transplantation·TypeExperimental study·DateJul 3, 2023
The sacrifice within – how collagen’s weak bonds help protect tissue
Scientists at Heidelberg Institute for Theoretical Studies discovered that collagen's weak sacrificial bonds rupture before the main structure, protecting tissue from excessive force. This mechanism helps to localize damage and promote recovery by dissipating mechanical stress and reducing oxidative stress in the body.
SourceHeidelberg Institute for Theoretical Studies (HITS)·JournalNature Communications·TypeComputational simulation/modeling·DateJul 3, 2023
Preventing stroke disability in a community with high rate of poverty
A new strategy targeting hospital procedures and community education led to a significant increase in thrombolysis rates, reducing post-stroke disability. The program, known as Stroke Ready, improved equity in stroke treatment for Black individuals who experience more strokes at younger ages.
Scientists discover how anti-viral cytokines can blunt the immune response to tuberculosis
A study published in Cellular Immunology reveals that type 1 interferons impair the metabolic response to Mycobacterium tuberculosis, making patients with chronic TB more susceptible to infections. The research identifies these cytokines as a potential target for developing new treatments.
Inadequate energy intake affects female athletes
A new study from Aarhus University reveals that female athletes who consume too little energy through their diet in comparison to their training volume experience negatively impacted muscles' ability to respond to training. The study shows that insufficient energy intake can lead to changes in the hormonal system, including a decrease ...
SourceAarhus University·JournalThe Journal of Physiology·TypeRandomized controlled/clinical trial·DateJul 3, 2023
Highly oxidizing magma of the early Earth
Researchers found that the early Earth's magma ocean was significantly more oxidized than today's mantle, leading to a CO2-rich atmosphere rich in SO2. This high oxidation state likely played a crucial role in supplying biologically available organic molecules and shaping the planet's habitability.
Fewer teens now perceive themselves as overweight – international study of more than 745,000 adolescents
A recent international study of over 745,000 adolescents from 41 countries found a decrease in those who overestimate their weight and an increase in those who underestimate it. This shift could reduce the effectiveness of public health interventions aimed at weight reduction in young people, as they may make unhealthy lifestyle choices.
SourceTaylor & Francis Group·JournalChild and Adolescent Obesity·TypeObservational study·DateJul 3, 2023
‘Traffic control’ system for mucin and insulin secretion identified
A study published in Nature Communications reveals the controlled release of mucins and insulin by cells, with tetraspanin-8 acting as a gatekeeper. The regulated secretion is biphasic, involving rapid and slower releases of granules, which can be targeted to reset deregulated mucin and insulin secretion.
SourceCenter for Genomic Regulation·JournalNature Communications·TypeExperimental study·DateJul 3, 2023
Birds raise fewer young when spring arrives earlier in a warming world
A new study found that birds produce fewer young if they start breeding too early or late in the season, with climate change resulting in earlier springlike weather. The researchers report that birds have been unable to keep pace with the changes, leading to a mismatch between the start of spring and birds' readiness to reproduce.
SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateJul 3, 2023
Pathogenic bacteria use a sugar in the intestinal mucus layer to infect the gut, study shows
A new study reveals that pathogenic bacteria fuel their growth by consuming sialic acid, a key component of the protective intestinal mucus layer. The findings suggest a potential treatment target for intestinal bacterial infections and chronic diseases linked to gut bacteria, including IBD and celiac disease.
SourceUniversity of British Columbia·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateJul 3, 2023
Dangerous chatbots: Prof. Stephen Gilbert calls for AI chatbots to be approved as medical devices
Chatbots with large language models can provide dangerous information, and their lack of explainability and bias control disqualifies them from being approved in the EU and US. Prof. Gilbert argues that new frameworks are needed to ensure patient safety.
Novel nanoprobe developed to detect diabetic retinopathy in its early stages
Researchers have developed a biodegradable fluorescent nanoprobe to detect diabetic retinopathy (DR) at its early molecular stage. The nanoprobe binds to VEGFR-2, expressed in the retinal microvessels, allowing for early diagnosis and intervention.
SourceBrigham and Women's Hospital·JournalBiosensors and Bioelectronics·TypeExperimental study·DateJul 3, 2023