Decentralized trials aim to improve access to clinical research, but disparities in technology access and potential barriers to trust remain unknown. Rigorous randomized controlled trials are needed to evaluate the impact of decentralized trials on trial enrollment and pipeline aspects.
A cross-cultural analysis of body-based measurements in 186 cultures worldwide found variations of the fathom, handspan, and cubit were most frequent, exhibiting striking similarities. Body-based units were especially common in ergonomic technologies like clothing and skis.
At ASCO 2023, Sylvester Comprehensive Cancer Center experts are available to discuss a wide range of topics, including Sarcoma research, tumor agnostic precision oncology, and genitourinary cancers. The center's experts also share their perspectives on immunotherapy approaches for prostate cancer, breast cancer treatment, and melanoma.
A team of scientists achieved a record-breaking 36.83km wireless broadband transmission from a ship to shore off the Irish Aran Islands using proprietary SeaFi technology. The new record surpasses the previous 2018 world record set by the same team, enabling private networks in ports and coastal areas for maritime businesses.
A randomized trial found that ultrasound diagnosis of forearm fractures in children resulted in similar recoveries and reduced the need for follow-up x-rays. The study suggests using bedside ultrasounds could alleviate hospital waiting times and costs, benefiting rural areas with limited access to healthcare.
A recent study found that adolescents across various ages, genders, and geographies are aware of and concerned about the potential impacts of abortion restrictions. The study, led by Dr. Bianca A. Allison, used a nationwide text message poll to gather responses from over 800 adolescents between 14-24 years old.
A new research effort aims to provide decision-makers with better information to understand supply chain risks, vulnerabilities, and resilience through visual analytics. The project will create a comprehensive computational and visual analytic environment to identify patterns and interdependencies in supply-demand systems.
A new study maps Australia's terrestrial and blue carbon soils, revealing the continent holds 27.9 gigatonnes of carbon, equivalent to 700 times annual electricity emissions. The research emphasizes the need to protect key ecosystems threatened by human activities and climate change.
Researchers from Japan discovered that firebrats, an old insect lineage, have a midgut epithelium derived solely from yolk cells. This finding suggests the involvement of bipolar formation likely originated in Pterygota rather than Dicondylia.
Physicians can remotely drive a miniature video capsule to visualize and photograph potential problem areas in the stomach using an external magnet and hand-held joysticks. The new technology has been shown to be effective in detecting high-risk lesions with a 95% rate of visualization.
A new study integrates robotics into wildlife conservation, enhancing predator deterrents through automated movement and adaptiveness. The findings demonstrate improved survival times and increased efficacy of protection against livestock predation.
A new study finds that boat strikes are increasing manatee strandings and injuries in Belize, with areas of high boat traffic and mangrove habitats showing higher risk. Conservation efforts should focus on reducing boat numbers and speed within protected zones to mitigate this threat.
The SISAQOL-IMI Consortium establishes an international consensus on patient-reported outcomes in cancer trials, aiming to improve the use of PROs. The new standards will enhance patient involvement and ensure the relevance of recommendations to the patient community.
A UK study of 3,745 families reveals significant inequalities in young people's financial capabilities depending on socio-economic background. The research highlights the need to develop financial skills in disadvantaged children as early as primary school.
Scientists discover hydrothermal deposits at a 5.7 km depth in the Japan Trench, indicating low-temperature hydrothermal activity and elevated CO2 and methane levels. The findings highlight the need for further studies on petit-spot volcanoes and their potential impact on global biogeochemical cycles.
Researchers discovered a way to dissipate heat near hot spots in semiconductors by utilizing surface plasmon polaritons. The new method increased thermal conductivity by 25% and has implications for high-performance semiconductor device development.
Scientists have developed a multi-layer, thin film sensor that automatically realigns during healing, mimicking human skin's layered structure. The material, comprising PPG and PDMS polymers, can self-heal and restore functionality without human input or effort.
The study found that smaller agri-SMEs owner-managed by women were more likely to experience disruptions in marketing and maintaining their labour supply. Larger agri-SMEs made changes to comply with government guidelines and sustained their business operations. Multi-faceted support packages are recommended to cushion these enterprises.
The MOSAIC project will use cutting-edge spatial omics technologies to map cancer cells and their immune environment in high resolution. By analyzing thousands of patient samples, researchers aim to unlock novel cancer treatments and biomarkers through AI-powered analytics.
Researchers discovered fragments of RNA viruses embedded in coral partners' genomes, dating back 160 million years. The discovery provides insights into how corals fight off viral infections and may hold the key to understanding the ecological impact of viruses on reef health.
A study analyzed tweets from nearly 500 emergency medicine physicians, finding a significant increase in expressions of loneliness, anger, and anxiety during the pandemic. Positive themes took a dive, while negative emotions dominated, with loneliness increasing by up to 17% compared to pre-pandemic years.
The MOLLER experiment has been granted Critical Decision-3A, allowing it to begin procurement of key components and make a precise measurement of the electron's weak charge, which will compare to the Standard Model's prediction.
The Gerontological Society of America's Journalists in Aging Fellows Program provides journalists with expert insight and support to cover aging issues. The fellowship has been instrumental in producing over 800 news stories, aiming to educate journalists about aging topics and disseminate information to diverse audiences.
Researchers at the University of Cambridge have developed flexible wooden partition walls using kerfing technology, allowing residents to adapt their spaces as needed. The innovative system aims to reduce waste and carbon emissions while providing affordable solutions for housing.
Cancer cells in brain tumors produce lipids at higher rates than surrounding healthy tissue, offering clues for treatment strategies. The study provides insights into the unique biochemical processes fueling cancer growth in the brain.
Research shows that bursts of electrical stimulation can modify activity in the subthalamic nucleus, influencing human behavior and potentially treating neurological disorders like Parkinson's disease. The study suggests a new approach to restore healthy brain function in people with these conditions.
A study published in The Lancet Psychiatry found that adolescents with signs of alcohol dependence are more likely to develop depression by their mid-20s. This association remained after adjusting for potential confounding factors, suggesting a causal relationship between alcohol dependence and subsequent depression.
Researchers analyzed 23 pregnant women with relapsed/refractory lymphoma and found a 24% progression-free survival rate and an 83% overall survival rate. The study suggests that delays in treatment may allow cancer to progress, while initiating chemotherapy can harm the fetus.
Researchers have uncovered a possible explanation for why frequent cannabis users are leaner and less prone to diabetes than non-users. The study found that adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood, leading to reduced fat mass and increased lean mass.
A study in Brazilian cities highlights the need for adapted nature-based solutions (NbS) to address environmental inequality. Municipal administrators are aware of NbS, but lack clarity on how to prioritize decision-making.
The NEC Society has released a neonatal probiotics toolkit to guide clinicians in deciding whether to implement probiotics to prevent NEC. The toolkit encourages multidisciplinary teams, including NICU family advisors, to foster informed dialogue and inclusive conversations about patient-families' health.
A new study by Flinders University research team led by Professor Justine Smith has found that women are more likely to experience recurrent cases of toxoplasmosis eye disease. The study also revealed significant differences in the type and characteristics of the disease between men and women.
The June issues of The American Journal of Psychiatry and Psychiatric Services focus on substance use disorders, opioids, and youth self-harm and suicide. The articles highlight the importance of addressing these issues to improve patient outcomes and reduce stigma.
The Global Research Council has ratified a charter of principles to promote equitable and diverse research practices. The document aims to establish common standards for assessing the quality of science produced, facilitating international collaborations and recognizing the value of different research activities.
A UTHSC research collaboration has been awarded a national grant to develop a new treatment for ovarian cancer. The project will test a newer generation of sabizabulin, a clinical candidate targeting microtubules in cancer cells.
Researchers from GIST have developed a hydrotropic-supporting electrolyte to enhance the solubility of organic redox molecules in aqueous systems. This improvement enables the creation of high-energy-density electrochemical capacitors with potential applications in redox flow batteries.
A new clinical trial found that low-dose atropine eye drops are effective in slowing the progression of nearsightedness in children. The treatment showed significant improvements in limiting eyeglass prescription changes and inhibiting elongation of the eye, with a daily drop in each eye being enough to make a difference.
A retrospective cohort study of over 66,000 older adults found that intensive antihypertensive treatment during hospitalization was linked to greater risk of adverse events. Treating asymptomatic elevated blood pressure in hospitalized patients may not be necessary and could lead to overtreatment.
Researchers analyzed 800 primate genomes to identify disease-causing mutations and provide insights into primate evolution, biodiversity conservation, and human uniqueness. The study highlights the importance of primate genetics in understanding human diseases.
Researchers at UCLA Health highlight the impact of test results on lung cancer screening adherence and the potential unnecessary use of axillary ultrasound in breast cancer diagnostics. Meanwhile, a new AI system helps check endotracheal tube placement with high accuracy and user satisfaction.
A new study published in JAMA finds that adding a coronary artery calcium score to traditional risk factor models improves CHD risk discrimination for middle-aged adults. The researchers suggest this non-invasive imaging technique could be a reliable predictor of heart disease, particularly in older adults.
The study provides new insights into primate speciation, genomic diversity, and phenotypic adaptability through comparative genomic analyses of 50 primate genomes. Genomic rearrangements across lineages have identified thousands of candidate genes undergoing adaptive natural selection.
Researchers evaluated three P recovery methods, finding struvite as the most societally feasible method. The study highlights significant benefits of P recovery, aligning with UN Sustainable Development Goals and promoting sustainable phosphorus supply.
Researchers at La Jolla Institute for Immunology have found that T cells can recognize shared viral targets between multiple coronaviruses, including common cold coronaviruses and SARS-CoV-2. This cross-reactivity could be harnessed to develop vaccines that protect against multiple types of coronaviruses, including SARS-CoV-2.
Researchers from Boston University identified several new genetic risk factors for Alzheimer's disease in a study of approximately 3,500 individuals of Ashkenazi Jewish ancestry. The study found strong associations with previously known variants and novel genes, including RAB3, SMAP2, and ZNF890P.
Researchers found that targeted deep-brain stimulation during a critical sleep cycle improved memory consolidation in patients with epilepsy. The study provided physiological evidence from inside the human brain supporting the main theory for how memory is consolidated during sleep.
ComboMATCH initiates patient enrollment to test new cancer drug combinations guided by tumor biology, exploring precision medicine and targeting proteins that control cancer growth. The project aims to identify beneficial therapies for patients with rare malignancies and/or rare molecular abnormalities.
An international team of researchers has developed a new method to study the thorium-229 isotope using lasers in the visible wavelength range. This approach could lead to precise measurements of the isomeric state's energy level, enabling tests of fundamental physics questions and potentially paving the way for a nuclear clock.
A new study explores the genetic mechanisms underlying honey bee colony defense and aggression, revealing that gene regulation influences collective behavior and division of labor. Researchers found that brain gene regulatory networks differ between soldiers and foragers, particularly in more aggressive colonies.
Researchers at the Institute for Basic Science have identified specific neurons in the hippocampus that allow us to recognize individual social counterparts and update their value through interactions. The dorsal CA1 region plays a crucial role in this process, enabling long-term memories of individuals to be formed.
Researchers analyzed the genomes of 233 nonhuman primate species, revealing key features of primate evolution, human disease, and biodiversity conservation. The study identified 4.3 million common missense mutations and developed phylogenies for primate species.
A new UNC study estimates that minority communities within 100 meters of major roadways face up to 15% higher PM2.5 and 35% higher NO2 exposure than white communities. The study reveals significant exposure inequities across the US, with vulnerable populations facing a greater burden of pollutants.
Scientists at Aalto University and MPS used petascale supercomputers to simulate the Sun's magnetic field, finding evidence for a small-scale dynamo that challenges conventional understanding. This discovery could lead to improved predictions of major solar events, providing vital extra time for preparation.
Researchers using NASA's James Webb Space Telescope confirm the existence of JD1, a tiny galaxy typical of those that burned through hydrogen left over from the Big Bang, enabling ultraviolet light to travel through space. The discovery sheds new light on the early universe's formation and reionization process.
A special issue of Science presents whole genome data from 233 primate species, providing a more complete understanding of primate genetic diversity. The study explores the association between genomic variation and variables like climate and sociality, shedding light on conservation efforts.
Researchers have developed a custom OCT setup that incorporates a vertical cavity surface emitting laser (VCSEL) diode, which could increase access to OCT imaging and help catch eye problems early. The system performed well in imaging the eye of a healthy volunteer and showed potential for use in biometric eye scanner systems.
A new study reveals Asian colobines living in colder regions underwent genetic changes and alterations to their social structure, forming larger, more complex societies. These adaptations allowed them to cooperate and survive in environments with low oxygen levels and extreme temperatures.
A new algorithm developed by a Munich research team can predict the effects of genetic mutations on RNA formation six times more precisely than previous models. The model focuses on splicing, a process that is thought to be one of the most common causes of incorrect protein formation and hereditary diseases.
A Eurac Research-led team tested drones' effectiveness in locating and providing first aid to injured people in difficult-to-access terrain. The study found that drone-assisted rescue operations reduced treatment time by 30% and saved critical minutes in cases of traumatic injuries and cardiac arrest.
In a multicenter trial, pirtobrutinib demonstrated reversible and effective inhibition of defective B-cells in patients with poor survival prognosis. Over half of patients responded to the drug, with a median duration of response of 21.6 months.