Researchers discovered that scandium doping and coating improve the durability and performance of sodium-ion batteries by stabilizing the crystal structure and suppressing side reactions. The study found that doping improves bulk stability while coating enhances surface stability, leading to improved capacity retention and long-term cy...
Alexis Grimaud, a leading researcher in battery materials chemistry, has received the National Science Foundation CAREER Award to support his work on developing new battery materials with improved energy density and scalability. His project aims to explore complex materials that can be used as battery electrode materials.
Engineers have created a bacterium that can consume all three major sugars present in corn stalks, opening up possibilities for more efficient biomanufacturing processes. The new strain of Pseudomonas putida was developed using an automated culturing platform and can potentially be used to produce valuable molecules like indigoidine.
National Jewish Health researchers identified disease-associated gene activity in macrophages and changes in immune cell communication in lung tissue. These findings may lead to targeted therapies and improved diagnosis of pulmonary sarcoidosis.
Researchers find that targeting Trk and IGF1R pathways can delay Ewing sarcoma tumor growth, but effect is temporary. NTRK gene expression associations with patient OS were found, indicating potential biomarker value.
Scientists created a single-cell atlas of spinal neurons to understand motor coordination and recovery from injury. The study identified a small subgroup of interneurons associated with speed, clarifying their role in controlling movement.
A recent study published in the Journal of the Endocrine Society suggests a link between exposure to phthalates and elevated blood pressure during pregnancy. Pregnant women with higher levels of fragrance-associated phthalates were found to have higher systolic and diastolic blood pressure markers, increasing their risk of hypertensive...
A new study introduces a computational framework that leverages alternative splicing events to predict protein isoform functions. The framework outperforms existing approaches and provides biological insights into how splicing shapes protein function, highlighting the importance of studying proteins at the isoform level.
Researchers analyzed patient data from five clinical trials to evaluate the impact of adding hormone therapy on postoperative radiation outcomes. While traditional pathological features can identify patients at higher risk of recurrence, they do not predict treatment benefit.
Industrial-scale illegal fishing accounts for 8-15% of global marine wild capture, with impacts unevenly distributed globally. Eliminating harmful subsidies and strengthening enforcement are key to addressing the issue.
Children who prefer to play alone but feel they belong in a larger social setting are often happy and content. In contrast, those who don't value belonging or feel like they don't fit in with their peers tend to be unhappy and dissatisfied with their relationships.
Scientists discovered that turbulence in air changes the timing of odor whiffs in systematic ways, creating patterns useful to animals. This finding bridges physics and neuroscience, with potential applications in search and rescue, hazardous chemical leaks, and mimicking animal navigation behavior.
A new study has found that women with endometriosis are at a 46% higher risk of developing type 2 diabetes. The study analyzed nearly 3 million women over 25 years and suggests that chronic inflammation associated with endometriosis may play a role in metabolic health.
Despite scientific progress, public faith in science is collapsing due to the proliferation of digital platforms and the democratization of access to information. This erodes trust as people rely on expert opinions without evaluating scientific claims for themselves.
Assistant Professor Yingxue Zhang's project aims to develop urban AI models that can efficiently process vast amounts of human-generated data to optimize commute times, traffic safety, and more. The model will utilize offline reinforcement learning to tackle spatial-temporal dynamics in urban life.
A team of researchers led by UMass Amherst believes a second, undiscovered internal clock regulates brain energy-intensive work and may link neurobiological brain function to the body's circadian clock. The three-protein clock has deep evolutionary precedent and disruption could contribute to human disease.
A new treatment framework for hepatocellular carcinoma (HCC) has been developed by a team of Johns Hopkins liver cancer experts, which provides guidance on best treatments based on tumor burden and biology. The BEACON-HCC framework incorporates emerging therapies such as external beam radiation therapy and novel combination therapies.
The partnership aims to increase enrollment in clinical trials, making research opportunities more accessible to patients. UCCCC and Lilly will work together to open studies faster and connect more patients with research opportunities.
Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in high-risk myelodysplastic syndromes (MDS), a discovery that could lead to more targeted treatments for this aggressive blood cancer. The study found that high-risk MDS stem cells are unusually dependent on nicotin...
Researchers found that OSKTF-mediated neuronal rejuvenation boosts rehabilitation-driven corticospinal tract (CST) repair after ischemic stroke. The study demonstrated that combining OSKTF expression with rehabilitative training significantly enhances CST axon sprouting and skilled locomotor function recovery.
In contrast to previous studies on human food-sharing practices, female Guinea baboons have diverse sources of meat and do not rely heavily on their primary males. The researchers observed that females often catch prey themselves and access alternative sources of meat.
Researchers discover that manipulating the chiral asymmetry factor of catalysts accelerates sulfur redox reactions, leading to higher capacities, superior rate capability, and remarkable long-term cycling stability in lithium-sulfur batteries.
Researchers engineered proteins to form highly reactive imidazolium intermediates, enabling precise control of molecular structures. The new family of enzymes demonstrates high selectivity and stereoselective bond formation, offering new ways for chemical synthesis.
A new study from the Hebrew University of Jerusalem examines Israel's philanthropic food-aid network, highlighting gaps in data and disparities in distribution. The researchers found significant limitations in evaluating the effectiveness, efficiency, and equity of charitable aid systems.
A systematic review examined rare tumor bleeding after radiosurgery for vestibular schwannoma, identifying reported symptoms and risk factors. The study highlights the need for personalized follow-up and individualized management strategies to prevent complications.
Physicists at TU Dortmund University demonstrate non-local synchronization of electron-nuclear spin oscillations, opening routes to controllable spin networks. Many time crystals can form in the same material and synchronize their oscillations, even at distances exceeding one thousand times the size of an individual oscillator.
A Rutgers Cancer Institute physician-scientist says a VA study comparing two hormone therapies for metastatic prostate cancer provides strong real-world evidence to help doctors choose the right drug for each patient. The study found that enzalutamide may offer a modest survival advantage for patients aged 75 and older.
A new study by Boston University researchers suggests that persistent hidden HIV proviruses contribute to chronic inflammation in people living with or without HIV. The findings highlight the importance of understanding these viruses to inform future treatments and strategies for healthy aging.
Researchers found that infected tadpoles preferred cooler temperatures and regulated their body temperature to slow viral replication. The study suggests that behavioural cooling may help animals combat viral infections, providing a physiological advantage over the detrimental effects of low temperatures.
Misha Blagosklonny's work challenged traditional paradigms in aging biology, proposing that persistent growth-promoting signals drive age-related pathology. His hyperfunction theory integrates evolutionary concepts with molecular pathways, offering a comprehensive framework for understanding aging.
Researchers identified NDRG1 as a key regulator of DNA damage repair, which can be targeted by the antimalarial drug quinacrine to trigger synthetic lethality in specific cancer subtypes. The study also reveals potential strategies for targeting DNA damage response based on NDRG1 expression.
Chao Zhang, PhD, receives $2.2M NIH grant to develop novel AI frameworks for investigating temporal changes in host-microbiome interactions. The project aims to characterize dynamic immune cell recruitment and uncover mechanisms underlying drug resistance.
Researchers at the University of Chicago have discovered a quantum phenomenon in a two-dimensional magnet that could be relevant for memory storage. The team found that one such material, Fe5GeTe2, exhibits a charge-ordered state where electrons move collectively and unusually slowly.
The pilot study explores the use of generative AI personas to facilitate structured empathy practice, with mean empathy scores increasing by 2.70 points and participants reaching the third level of a relational progression framework. However, further research is needed due to methodological limitations.
The REMADE project aims to transform building renovation in Europe through a neighbourhood-centred Renovation-as-a-Service model, combining design for adaptability and disassembly with advanced digital tools. The project will develop energy-efficient technologies and circular economy construction processes that support the EU's sustain...
A new study by MIT researchers aims to give the budding industry a framework for understanding how fusion can be profitable. The method considers the physical inputs needed to sustain controlled fusion energy production and the cost of building power plants that can compete in energy markets.
A study discovered a possible epigenetic mechanism that primes the 'Shuxinyou' (SXY) cultivar of Aquilaria sinensis for high-yield agarwood production. SXY accumulated more alcohol-soluble resin extract and showed stronger terpenoid biosynthesis after controlled wounding.
Researchers developed a mathematical model that suggests adjusting treatment schedules over time may be more effective in managing tumors than rigid treatment plans. The study found that continuous therapy, rather than on-and-off treatment, can control the tumor and reduce toxicity, improving patient outcomes.
An international study of 974 participants aged 50-94 found a strong correlation between ageist attitudes and self-reported memory failures. The results indicate that individuals with more restrictive views on older adult behavior experienced greater memory problems, regardless of their country of origin.
The new integrations provide enterprise AI agents direct access to live, structured research data from Dimensions' 430M+ interconnected records. This allows for AI-assisted analytics across one of the world's most comprehensive linked views of global research activity.
A new study examines the KEYNOTE-689 trial cohort to determine whether anticipated survival benefits outweigh the costs based on a standard threshold. Patients with higher combined positive scores saw significant quality-adjusted life years gains with perioperative pembrolizumab.
Researchers at McMaster University have discovered a naturally occurring hormone, GDF15, that activates a brain-to-liver signaling pathway to suppress liver inflammation and slow the progression of liver scarring. The findings suggest future treatments may be able to complement existing weight-loss therapies.
Research reveals that selective breeding and training have altered brain pathways related to vocal processing and cue interpretation in dogs. Trained service dogs show stronger connections between communication-related brain areas, suggesting trainability can be predicted by brain connectivity.
The collaboration aims to improve human tolerance to xenogeneic organs and reduce the risk of organ rejection. Researchers will explore immunomodulatory interventions to support patients with high unmet needs who face additional barriers to receiving timely liver transplants.
The SNU team introduces Cluster-aware Upcycling, leveraging semantic structure of pretrained models to promote specialization among expert modules. This approach outperforms conventional Sparse Upcycling on image-text retrieval and various image classification benchmarks.
A research team discovered an epigenetic mechanism in Aquilaria sinensis cultivar SXY that enables efficient agarwood production. The study found that pre-existing chromatin accessibility prepares metabolic genes for rapid activation after injury, supporting molecular screening for high-yielding cultivars.
A study of 441,844 UK Biobank participants found that a healthy lifestyle can cut the risk of hearing impairment by 14%, with metabolic biomarkers playing a dominant role. Metabolic dysfunction was identified as the primary biological pathway linking lifestyle to auditory health.
A new study by Adelaide University researchers found that higher cumulative doses of clomiphene citrate increase the risk of miscarriage and twinning, but do not improve live birth rates. The study analysed over 21,000 embryo transfer cycles and found a dose-response relationship between cumulative doses and adverse pregnancy outcomes.
A new study uses spatial transcriptomics to map the molecular evolution of prostate cancer and identifies key genes associated with disease progression. The research reveals that genetic malignancy in specific glandular epithelial regions tightly aligns with increasing clinical Gleason scores.
The rotational chair test offers unique diagnostic value for various vestibular disorders, detecting residual function and subtle deficits. It supports personalized rehabilitation and guides treatment for conditions like Ménière’s disease and persistent postural-perceptual dizziness.
A three-year study found that posterior scleral reinforcement slowed macular fundus tessellation and preserved subfoveal choroidal thickness in children with progressive high myopia. The researchers suggest that PSR may help delay early myopic maculopathy-related changes, possibly through mechanisms beyond axial elongation.
Researchers at Queen Mary University of London developed a graphene-based material for soft lenses that can change focus electronically without bulky moving parts. The technology has the potential to open up new applications in medical imaging devices, autofocus cameras, wearable displays and scientific instruments.
Researchers found that upper and lower surfaces of oak leaves support different microbial communities, with the upper surface hosting stress-tolerant genera and the lower surface favoring sugar-fermenting taxa and insect-associated bacteria. The two sides show striking seasonal divergence in terms of diversity and abundance.
Researchers develop platform generating complex VOFs with spatially tailored wavefront profiles and polarization distributions, showcasing exceptional capabilities in multifunctional beam shaping and complex wavefront engineering. The platform enables independent control over amplitude, phase, and polarization of radiation fields.
A new ten-point framework for diabetes prevention aims to restore metabolic health across the entire life course, targeting risk factors before disease onset and emphasizing remission. The framework identifies key priorities, including personalized prevention strategies, digital tools, and reducing health inequities.
FPP is evolving from geometric triangulation to light transport analysis with AI and CI, expanding its capabilities beyond shape acquisition. The new framework enables a deeper understanding of light transport, material properties, and scene formation mechanisms, opening opportunities for intelligent perception technologies.
The 46th COSPAR Scientific Assembly brought together over 3,000 participants to exchange the latest results in space research and strengthen international scientific collaboration. Key highlights included a Space Agency Leaders Roundtable, Humanity's Cross-Disciplinary Exploration panel, and the first-ever Dark and Quiet Skies event.
A new study by Dr. Wu Yuan's team reveals that retinal AI can lose accuracy in high-altitude populations due to altitude-associated domain shift. MIXFound, a lightweight framework, offers a practical solution to improve robustness and correct for these differences.
Researchers found that eustress reduces CCL2 expression, alleviating cardiac damage and enhancing chemotherapy response. Eustress also remodels the tumor immune microenvironment, increasing cytotoxic CD8⁺ T cells and anti-tumor M1-type macrophages.
Researchers developed a novel parallel-risk framework to optimize precision transplantation for pediatric patients with acute myeloid leukemia. The framework successfully identifies which patients will benefit from stem cell transplantation directly at diagnosis, overcoming diagnostic biases and subjective clinical assessments.