The study found that Nematostella carries eight of the ten proteins humans use to pair and align meiotic chromosomes, making it a promising system for understanding human fertility. The sea anemone's proteins show unexpected flexibility in their roles, revealing new insights into meiosis and its potential impact on fertility.
Researchers found that larger movements improve learning on similarity-based categories, but not on rule-based categories. The study suggests that movement shapes learning itself, rather than just responding to visual stimuli.
Cancers can evade chemotherapy by entering a 'zombie-like state' called premature senescence, which tricks the immune system into helping malignant cells. This phenomenon allows tumours to acquire extra oxygen and nutrients, making them more resistant to chemotherapy.
A study discovered that an ancient viral remnant in chimpanzee DNA silences a key gene, LINC00662, which is active in humans and plays a role in early brain development. This finding highlights the importance of understanding gene regulation and its potential link to brain diseases.
Researchers at the Centre for Genomic Regulation have discovered a six-gene scoring system that reliably predicts patient survival in acute myeloid leukemia. The PHFScore system, which combines the activity of six genes, can divide patients into groups with sharply different survival prospects.
A new study reveals evidence of east-west genetic exchange and long-term population continuity in southwestern Europe, linking populations across thousands of years. Genetic data from rare human remains and cave sediments provide key insights into the Gravettian culture.
Researchers at the University of Melbourne found that knowing the Pacific Ocean's state at the beginning of a forecast can provide valuable clues about a forecast's reliability one year later. Forecasts initiated during La Niña conditions consistently performed well, while those starting from neutral conditions were less reliable.
Researchers at the University of Pennsylvania have developed a novel insulator using stacked Mylar sheets, which combine strong thermal insulation with mechanical durability. The material, called hybrid layered insulating film stacks, has been tested in a vacuum and shown to maintain its thermal performance under compressive stress.
The TOSYMA study found that tomosynthesis detected significantly more invasive breast cancers than mammography, with a 24% lower rate of interval cancers over two years. This suggests that tomosynthesis may be more effective in preventing aggressive interval cancers.
Farell Keiser, a high school student, published a paper in Physical Review B as the first author, showcasing his substantial contribution to the field of terahertz research. His work focused on zinc telluride and demonstrated a more accurate physical description of terahertz generation in the material.
Researchers developed a new genetic animal model that closely follows UCP1 expression in brown and beige fat, reducing unintended genetic activity in the brain and other tissues. This model provides a precise way to study the contribution of thermogenic adipose tissue to metabolism, energy expenditure, and metabolic health.
A Northwestern University study found that disaster recovery efforts provided temporary boosts in mental and physical health for younger and retired men, but middle-aged men and elderly men did not experience similar benefits. As recovery activities ended, the boost declined, leaving elderly men worse off in the long run.
The therapy showed consistent efficacy and a manageable safety profile, with outcomes similar to those in the VISION trial. The findings support the use of PSMA-targeted radiopharmaceutical therapy in routine care for patients with mCRPC, including those eligible for retreatment.
Researchers evaluated PET imaging with radiolabeled trastuzumab deruxtecan and targeted alpha therapy against HER2-positive cancer cells, revealing promising results in tracking therapy accumulation and suppressing tumor growth. PET imaging also linked metabolic patterns to pancreatic tumor outcomes and identified potential distant met...
Henry Ford Health has enrolled the first US patients in a clinical trial evaluating pulmonary artery denervation, a treatment for pulmonary hypertension related to heart disease. The trial aims to determine the safety and effectiveness of the investigational treatment.
A new analysis of a phase 3 clinical trial found that daraxonrasib improved survival compared with standard chemotherapy across multiple groups of patients with advanced pancreatic cancer. The treatment consistently provided a benefit regardless of tumor RAS mutation status or previous treatment history.
Researchers have identified two new mushroom species in Japanese lawns, revealing overlooked fungal diversity in managed environments. The discoveries extend the species' known distributions eastward and suggest an association with disturbed grasslands maintained through human activity.
A new AI model, developed by the University of Cincinnati Cancer Center, aims to improve breast cancer survival prediction by combining statistical methods and deep learning. The model analyzes clinical and genetic data to provide more personalized care decisions for each patient.
Researchers at St. Jude Children's Research Hospital uncovered a mechanism behind PARP1-mediated DNA repair, revealing a previously undescribed role of the enzyme in chromatin remodeling. This discovery has implications for cancer treatment, as it may provide a way to target cancer cells while sparing healthy tissues.
Cases of Ebola in Kenya and Nigeria highlight the need for preparedness, with the EU/EEA population considered at very low risk of infection. ECDC emphasizes the importance of continued preparedness and adherence to recommended precautions to prevent the spread of the virus.
Chilean researchers are calling for accelerated action to address the biodiversity crisis, emphasizing the need for resources, international cooperation, and scientific tools to implement global commitments. The Institute of Ecology and Biodiversity is highlighting the importance of conservation financing and scientific validation to e...
A new study examines the impact of Operation Soteria on rape and serious sexual offence cases, finding progress in victim-centred investigations but challenges in the court system. The report highlights the need for a whole-system approach to tackle rape and serious violence, ensuring swift, fair, and responsive justice for victims.
A national study of 18,000 LGBTQ+ college students found that those experiencing discrimination are more likely to experience depression, anxiety, and suicidal thoughts. The study highlights the need for colleges to address discrimination as part of comprehensive suicide prevention efforts.
A new study demonstrates that embedding mindfulness practices into DNP curricula effectively reduces stress and combats burnout. By equipping nurse leaders with practical emotional regulation tools, the initiative supports core competencies in person-centered care and leadership development.
Geometry-based kinetic simulations reveal conditions for improving DNA-nano/microparticle motor speed, run length, and unidirectionality. Large particles can increase run length and unidirectionality due to increased DNA/RNA duplex formation, while small particles retain room for further acceleration.
Researchers from Singapore and China have discovered a hidden property of Smith-Purcell radiation, known as chirality, in light emitted from electron beams. By rotating or shifting a plain silicon grating, they can bring out the chirality, which has potential applications in building compact, tunable light sources.
An international research team has developed a method to isolate and characterize the endoplasmic reticulum membrane from mammalian cells. The team's findings reveal that different regions of the organelle are composed of the same membrane lipids, despite being stabilized by different proteins.
A patient in France has been infected with the Shamonda virus, a disease that has previously only affected animals. The European Centre for Disease Prevention and Control is investigating the potential public health implications of this case and working with European partners to strengthen response planning.
Blocking the CD44 molecule in pancreatic cancer-associated fibroblasts can alter tumor-promoting cells in the tumor microenvironment, leading to improved prospects for treatment. The study suggests that targeting CD44 in the supportive tissue could be therapeutically promising, although further research is needed.
A new study reveals the complex interplay of evolutionary forces that shape some of the world's most versatile natural products, including potent antibiotics and insecticides. Researchers discovered 49 distinct compounds produced by bacteria, including previously unknown variants, and found evidence for natural selection, genetic drift...
Researchers created a new catalyst by combining nickel with molybdenum carbide, allowing oxygen to selectively trap and form temporary oxycarbide species. This setup unlocks a new reaction mechanism, significantly lowering the energy barrier for methane activation and improving the catalyst's stability.
A Chinese Neurosurgical Journal study identified promising pharmacological and non-pharmacological strategies for managing agitation after traumatic brain injury. The study highlighted the need for more precise measures and larger clinical trials to guide safer, evidence-based care.
The book examines molecular mechanisms of biofilm formation and quorum sensing, highlighting their roles in microbial pathogenesis and antimicrobial resistance. It explores emerging strategies for controlling biofilms, including quorum quenching, phytochemicals, and phage therapy.
The book examines the intersection of liver health, public health policy, and welfare initiatives, highlighting the importance of prevention, early diagnosis, and accessible healthcare. It also explores innovative policy approaches and practical recommendations for strengthening healthcare systems and reducing health inequities.
Researchers developed a new way to make glowing biological reporters more accurate, allowing scientists to track gene activity in living plants over days and weeks. The approach overcomes limitations of self-sustaining luminescence, providing a reliable readout of biological processes.
Research from Michigan Medicine found that combining online resources and phone-based coaching increased genetic testing rates by 5% after six months and 10% after a year. The interventions aimed to overcome barriers to testing, including lack of knowledge and fear, and tailored approaches for individual needs.
Researchers at Heriot-Watt University have discovered that combining fava bean protein with potato protein can create a firm, fibrous structure similar to meat. However, the potato protein version has a bitter taste and a stronger lingering aftertaste, which needs to be addressed for widespread use.
The tools, Hallucination Nerd and Protocol Nerd, use AI to identify supported claims in academic citations and suggest relevant experimental protocols for scientific studies. They were validated using research databases and showed promising results in detecting citation hallucinations and identifying effective protocols.
A massive genetic study has identified 1,260 associated variants with five major personality traits, showing that thousands of tiny genetic effects contribute to personality alongside environmental influences. The study found that common genetic variants explained about 5 to 9 percent of the differences in personality, and that genetic...
A new study published in Virtual Reality found that electroencephalography (EEG) can detect changes in brain wave activity while participants view virtual content designed to induce cybersickness. The researchers identified specific brain signals associated with the vergence-accommodation conflict, a mismatch between eye movement and f...
The new standard/guideline provides evidence-based recommendations for conducting and interpreting lung imaging, incorporating recent technological advances. It aims to promote comprehensive patient assessment and improve diagnostic accuracy, reproducibility, and patient outcomes.
Ecological water scarcity affects 412 river basins worldwide, with 29% of the study area impacted and 35% of global population covered. Human interventions drive the problem, and climate mitigation can reduce future risks, but ecosystem restoration and water conservation are needed.
Grasslands and other open ecosystems store vast amounts of carbon while supporting biodiversity and water supply, yet are ignored by climate finance policies. These ecosystems provide critical ecosystem services, including carbon storage and water replenishment, but lack recognition in current climate finance mechanisms.
Researchers investigate whether black holes can split into two smaller ones, finding that rapid rotation may provide a possible loophole. The study proposes a new term, 'pair-of-pants topologies', to describe the hypothetical trouser-like shape formed by the resulting black holes.
Insilico Medicine executives will share insights on leveraging generative AI in drug discovery and healthcare delivery at Dubai AI Festival 2026 and the 2026 Global Healthcare Innovation Summit in Hong Kong. In Seoul, Dr. Jue Wang will deliver a keynote on maximizing AI's value in AI drug discovery at BioPlus-Interphex Korea 2026.
Researchers developed an integrated bioprocess to produce antifungal bioproducts from winery waste, reducing mycelial growth of grapevine pathogens by 45-75% and symptoms of wood discoloration by 47-52%. The process uses fermentation design, ultrasound-assisted autolysis, and enzymatic hydrolysis to yield active peptide mixtures.
The study found that market interconnectedness increased sharply during both crises, with markets responding more strongly to the same global pressures. The research revealed that the strengthening of connections happened quickly, with strong links between US and European markets appearing within three trading days.
This study investigated the effects of mycorrhizal type and life form on resource-use strategies in woody plants of the Qinling Mountains. The results showed that arbuscular mycorrhizal (AM) species exhibited acquisitive trait signatures, while ectomycorrhizal (ECM) species followed conservative strategies. Life forms also modulated le...
Researchers found that hydrogen supplementation had no significant effect on sleep quality, but individuals with lower gut microbiome hydrogen production showed greater improvements. The study suggests that individual differences in gut microbiome may influence response to hydrogen supplementation.
Researchers call for coordinated research and public education to understand how microorganisms drive chronic disease and how to harness them for repair. The plan identifies 10 priorities, including pregnancy and early childhood, and recommends public education to inform everyday decisions.
Researchers propose targeting G protein-coupled receptors to slow aging, exploring AI, systems biology, and digital twins for therapy design. The approach could work alongside senolytic, metabolic, and regenerative strategies.
A new study proposes using supercurrent to read quantum information without destroying it, eliminating the need for auxiliary circuits. This method uses the oscillating electric supercurrent produced by an Andreev qubit to encode and decode the qubit's state, enabling virtually non-destructive quantum readout.
A new study estimates that PFAS levels in US drinking water may be up to 50% higher than reported levels, highlighting the need for improved monitoring and reporting. Researchers used a model based on national data to estimate PFAS concentrations in community water systems.
The Optica Board of Directors has elected 116 members from 23 countries as 2027 Fellows for their outstanding contributions to optics and photonics. The new Fellows will be honored at Optica conferences and events throughout 2027.
Children who consume more ultra-processed foods show stronger brain responses to appetizing foods, linked to increased body fat. Stronger responses in the brain's reward network are associated with greater increases in body fat over one year.
JMIR Publications releases five news and perspectives on digital health, covering AI-driven CPR training, GLP-1 ads' impact on body image, and innovative solutions for postpartum psychosis detection, aiming to improve patient care and awareness of emerging health issues.
Researchers have developed a bilayer terahertz metasurface design strategy based on S4 point-group symmetry, achieving robust quasi-bound states in the continuum with high Q-factors and enhanced resistance to fabrication defects.
Scientists successfully generate tetraploid iPS cells through cell fusion, which replicate the natural chromosome doubling process in mature cardiomyocytes. This breakthrough enables the development of a technology to enhance cardiac function, offering new therapeutic strategies for diseases such as heart failure.
Prof. Robbert Dijkgraaf takes office as ISC President, calling for science to be recognized as a global public good. He aims to defend academic freedom, strengthen international collaboration, and mobilize science for global challenges such as climate change and biodiversity loss.
EPFL researchers have developed an implantable neural chip that can track communication between brain regions, identifying cognitive and emotional states in real-time. The system, dubbed LogSync, uses machine-learning algorithms to analyze brain activity and generate stimulation triggers when specific states are detected.