The study found that S. aureus significantly intensifies ZnO nanoparticle-induced oxidative stress, inflammatory signaling, and cellular damage. The authors suggest that considering the skin microbiota is crucial for evaluating nanoparticle safety.
A humanitarian medical delegation of Israeli medical students is operating in Kenya as part of the
A new study shows that targeted cancer drug selpercatinib can significantly reduce the risk of lung cancer returning in patients with a rare genetic subtype. After two years, 92% of patients remained cancer-free, compared to 61% who received a placebo.
The new method allows for scalable production of cell-containing capsules, maintaining cell viability and enabling studies on dynamic interactions. Researchers can customize capsule size and properties, making the technique useful for drug screening, regenerative medicine, and basic cell biology research.
Researchers have developed a defect-engineered TiO2/Zn0.5Cd0.5S S-Scheme heterojunction for enhanced photocatalytic H2 evolution, achieving superior efficiency and stability. The synergistic integration of oxygen vacancy and S-scheme charge transfer pathways enhances light absorption, electron separation, and redox capacity.
A global report warns of a looming shortage of nearly 100 million cancer care workers by 2050, driven by rising cancer rates and workforce gaps. This will place significant strain on health systems worldwide, particularly in nursing and diagnostic roles.
A study published in the New England Journal of Medicine shows an investigational targeted therapy, daraxonrasib, significantly extends overall survival for patients with metastatic pancreatic cancer, reducing death risk by 60%, compared to standard chemotherapy.
Researchers develop a new material design to overcome kinetic and stability issues in sodium-sulfur batteries, enabling fast-charging capabilities. The innovative pisiform homojunction creates a p-n interface that accelerates polysulfide conversion and stabilizes battery performance.
A recent study analyzing 670,000 patients found a higher frequency of advanced disease among non-white men and differences in access to modern therapies. The study also revealed significant racial inequalities in treatment costs, with white patients receiving 16.2% more funding.
The Oregon State University-developed technology allows for the measurement of chemical and biological actions at the femtosecond level, enabling scientists to understand the exact sequences of biochemical reactions. This knowledge helps design effective cleanup methods by identifying vulnerable points in the molecule.
A Phase 3 trial showed a 56% reduction in the risk of disease progression or death for patients with BRAF V600E mutant metastatic colorectal cancer treated with a targeted therapy combination. The treatment improved median progression-free survival and overall survival, with nearly 75% of patients alive at 18 months.
A study found that a specific pattern of brain metabolism visualized with PET imaging can predict which patients are most likely to benefit from Alzheimer's disease therapy. Patients with this pattern experienced stabilized cognitive performance, while those with other patterns had significant cognitive decline.
Researchers developed a new tau PET radiotracer that can accurately detect chronic traumatic encephalopathy (CTE) in living patients. The tracer's ability to bind to tau pathology was confirmed in post-mortem CTE tissue, and preliminary results suggest it could provide an early diagnostic biomarker for the disease.
A new type of peptide receptor radionuclide therapy (PRRT) shows promise in treating metastatic neuroendocrine tumors. The novel approach resulted in partial remission in the majority of patients with advanced cases, with manageable safety and encouraging antitumor activity.
A new laser-based process is set to revolutionize photonics manufacturing by removing manual calibration, which accounts for over half of production costs. The technology promises faster, cheaper, and precise manufacturing at sub-micron tolerances.
A new SPECT/CT imaging approach can accurately differentiate between inflammation and fibrosis in interstitial lung disease (ILD) patients. Researchers used the molecular imaging agent ⁹⁹ᵐTc-maraciclatide to visualize inflammation, which is crucial for determining treatment decisions.
Researchers found deer keds, biting flies that live as parasites, shed wings and reduce visual sensitivity to conserve energy. After finding a host, these flies prioritize digestion and reproduction over vision.
The £10 million Natasha's Prize aims to develop solutions to prevent food allergy by focusing on prevention. Leading scientists from various disciplines will be invited to apply and brainstorm ideas to stop food allergy development in the first place.
Research from University of East Anglia finds that TikTok content glamorizes illicit vaping, attracting young people and exchanging tips on bypassing age restrictions. The study suggests that legislation alone may not be enough to combat the issue, highlighting the need for platforms to take action.
Global wildfire activity in 2025 resulted in destructive and deadly fire events, with 335 million hectares burned globally - 16% below the long-term average. The fires accounted for 38% of all insured natural hazard losses, with Canada experiencing its third consecutive year of extreme fire activity.
Researchers have developed a way to improve records of past high-latitude ocean change by analyzing tiny plankton shells called foraminifera. The new calibration tool extends the key temperature tool into colder seas, enabling more accurate reconstructions of climate and ocean circulation changes.
PSMA PET scans have been shown to detect bone metastases that conventional imaging misses, resulting in faster disease progression and worse overall survival. Patients with these undetected lesions are at a higher risk of progressing to treatment-resistant cancer and dying sooner.
Researchers developed a novel PET imaging approach to detect immune-related adverse events in patients receiving immunotherapy. The approach uses CCR2-targeted radiotracer to visualize both tumor progression and cardiac inflammatory responses. Co-treatment with itacitinib improved tumor response while reducing cardiac inflammation.
Johnson aims to protect and advance the scope of practice for nuclear medicine technologists, strengthening the national workforce pipeline through education-driven partnerships with industry. She will also formalize standardized training resources as new technologies are introduced.
Shannon Youngblood has been elected as the new president of the SNMMI Technologist Section. She will focus on amplifying visibility through advocacy, building a more inclusive workforce through educational opportunities, and streamlining professional development to stay current with advancements in theranostics and cardiac PET-CT.
Dr. Richard E. Carson has made significant contributions to the understanding and application of nuclear medicine, particularly in neuroscience and neuropsychiatric disorders. His work led to the development of diverse tracer kinetic modeling techniques and innovative imaging systems like NeuroEXPLORER.
Irène Buvat, a pioneering researcher, has received the SNMMI's George Charles de Hevesy Nuclear Pioneer Award for her groundbreaking work in molecular imaging quantification. Her contributions have led to improved diagnosis and treatment of cancer through the development of simulation and radiomics tools.
A scoping review compared biosimilar regulatory guidelines across all WHO regions, identifying barriers to data transferability that may affect medication pricing, access, and reimbursement. The study aims to improve biosimilars' global accessibility.
A new study by Penn Medicine reveals significant gaps in online information about artificial intelligence (AI) and its impact on cancer research and treatment. The study found that only 33% of relevant webpages and 23% of videos were considered high-quality, with many omitting risks of AI use.
A study from UC San Francisco researchers reveals that regulatory differences around the world are slowing the development and adoption of biosimilars. The lack of standardization in biosimilar approval processes is a major obstacle for these cheaper alternatives to expensive biologics, which could lower costs for patients.
The study found that population-based pathogenic variant testing reveals different subsets of high-risk women than clinical risk factors and polygenic risk scores. This highlights the importance of incorporating PV testing into risk-based screening for breast cancer.
Institutional Special Needs Plan (I-SNP) enrollment was associated with significantly fewer hospitalizations for nursing home residents with dementia at the end of life, according to a retrospective cohort study. Effect sizes were larger for UnitedHealthcare (UHC) I-SNPs vs non-UHC plans. Plan maturity and volume likely impact success.
The study demonstrated a response to treatment in several tumor types, including lung cancer and head and neck cancers. A significant tumor shrinkage was observed in four out of 14 patients treated within the optimal dose range.
A phase 3 clinical trial found that apalutamide plus hormone therapy before and after surgery reduced the risk of metastasis or death by 20% compared to hormone therapy alone. Patients treated with this regimen had a higher pathologic response rate and experienced delayed subsequent therapy.
A phase 3 trial shows daraxonrasib, an oral RAS(ON) multi-selective inhibitor, improves overall and progression-free survival compared to chemotherapy in patients with metastatic pancreatic cancer. The treatment also demonstrated substantial tumor shrinkage or disappearance in patients with a known RAS G12 mutation.
Researchers discovered a novel Fe-N-C protective layer that enhances the stability of platinum-based fuel cell catalysts. The 'core-shell' design shields platinum from corrosion and creates a powerful electronic interaction at the interface.
A new machine-learning model uses pre-therapy PET/CT scans to estimate radiation dose to tumors and healthy organs, improving patient selection and reducing toxicity risk. The study's findings suggest a promising ability to predict post-therapy dosimetry, which may optimize treatment plans for individual patients.
A population-based screening trial evaluating a cell-free DNA multicancer early detection test found modest increases in diagnostic delay rates for head and neck, lung, and upper gastrointestinal cancers. These findings suggest that future trials may need to consider system-level spillover effects on healthcare resources.
A recent immigration ban could reduce the US physician and nurse workforce, exacerbating health care workforce shortages in already underserved communities. The study found nearly 24,000 physicians and 56,000 nurses from banned countries contributed to the US healthcare workforce in 2023.
The Society of Nuclear Medicine and Molecular Imaging recognized six new Fellows for their exceptional contributions to the field. The SNMMI Fellowship honors members who have demonstrated excellence in scientific discovery, educational efforts, or clinical practice.
This study found that Justicia carnea ethanol extracts effectively reduced oxidative stress markers, inflammation, and lipid peroxidation in a mouse model of chronic pancreatitis. The extracts also preserved islet glucagon expression, indicating potential therapeutic benefits for pancreatic damage.
This AAV platform integrates MGS4 peptide-guided capsid targeting, hypoxia-responsive elements, and dual shRNA vectors to selectively deliver chemokines and PNAi to NSCLC tumors. The combination of these elements aims to enhance antitumor immunity while suppressing tumor invasiveness.
A multicenter clinical trial found that implanting collagen tiles during brain surgery improved tumor control and lowered the risk of recurrence by 12.1% compared to current standard of care. Patients treated with tile-based radiation therapy (TBRT) had a median overall survival of 42.5 months, more than double the 17.6 months seen wit...
Vasken Dilsizian, MD, has received the Minoshima-Pappas Transformational Leadership Award for his vision and leadership in advancing nuclear medicine and molecular imaging. He has made significant contributions to the field of cardiovascular diseases through his innovative scientific work.
Scientists have identified dopamine as a key player in mediating stress-induced courtship suppression in male Drosophila fruit flies. The duration of stress exposure significantly influenced the persistence of suppressed courtship behavior, highlighting the importance of dopamine signaling in this process.
Cleveland Browns cornerback Denzel Ward is promoting Hands-Only CPR and empowering bystanders to save lives through a new American Heart Association campaign. The campaign aims to close the gap of bystanders performing CPR only about 41% of the time.
A recent study published in Cell has found that certain plants actively reduce their ability to take up iron when experiencing drought stress. This shift is driven by changes to plant roots that downregulate both immune systems and iron uptake machinery, allowing specific bacteria to thrive.
Couradeau will investigate how biocrust microbiomes adapt to thermal fluctuations, with implications for soil stability, fertility, and ecosystem services. Her research project includes novel components such as mesocosm experiments, global survey datasets, and citizen-science education.
A study by Brown University researchers found that exposure to violence is strongly associated with increased tobacco and e-cigarette use among adolescents. The study analyzed data from the Youth Risk Behavior Surveillance System and found that each form of violence exposure was linked to increased risk of using both substances.
Researchers from NYU Langone Health's Perlmutter Cancer Center presented new clinical findings on Merkel cell carcinoma, showing improved outcomes with pembrolizumab treatment. Additionally, a national study found that lung cancer screening has widened income-related gaps in survival rates, highlighting the need for equal access to care.
A new study published in JAMA found that using a cryoprobe for lung biopsies significantly increases the diagnostic yield compared to standard forceps, with nearly 10 percentage points higher accuracy. The 1.1-millimeter cryoprobe was shown to be safer and more effective than larger probes without crushing tissue samples.
Researchers at University of Illinois have developed a new process to stack silicon layers, enabling faster and more efficient chips. By sequentially building each layer on top of the previous one, they achieved high device performance across multiple tiers while meeting thermal constraints.
Researchers argue that biochar's long-term carbon storage potential and its soil improvement benefits should not be conflated. The authors call for a 'designer biochar' approach, tailoring products to specific end uses rather than marketing them as universally beneficial.
Researchers found that hydrochar improves soil structure while increasing soil organic carbon, with different feedstocks showing varying benefits. The study suggests hydrochar could become a customizable amendment for climate-smart soil management.
The NRG Oncology trial showed a sustained overall survival benefit for patients with advanced or recurrent endometrial cancer treated with pembrolizumab and chemotherapy, even after post-study immunotherapy. The benefit persisted in both mismatch repair proficient and deficient populations.
Researchers developed amine-functionalized biochar/cellulose acetate hybrid membranes using microalgae biomass, improving water filtration and reducing foulant adhesion. The modified membranes achieved a water flux of 169.1 L m⁻² h⁻¹ and 64.1% removal of natural organic matter.
Researchers at Columbia University have discovered a key mechanism in the formation of toxic tau filaments that contribute to Alzheimer's disease. The findings suggest that disrupting neuroproteasomes can trigger misfolding of tau into highly similar filaments, and that APOE variants may play a role in modulating this process.
The University of Tennessee at Knoxville is launching the Knoxville Quantum Accelerator, a collaborative effort to develop and commercialize quantum technologies. The initiative will support the development of an ecosystem that advances both fundamental discovery and applications.
A large international clinical trial led by UCL found that a gene test can safely spare many breast cancer patients of chemotherapy. The OPTIMA trial followed over 4,400 patients and suggested that those with hormone-sensitive breast cancer and low Prosigna scores can be treated safely with hormone therapy alone.
Researchers at Texas A&M University are designing how humans will build and survive on the moon, focusing on sustainable construction using lunar regolith. The institution's efforts aim to reduce costs associated with shipping materials to the moon, making it possible to produce rocket propellant locally.