The partnership aims to generate evidence on the potential of MitoQ to slow or improve markers of biological ageing and support longevity. Mitochondria-targeted antioxidants like MitoQ are crucial in producing energy while reducing oxidative stress, a key contributor to ageing.
A new portable sensor developed by Griffith University can rapidly detect 'forever chemicals' in water at a lower cost than traditional laboratory-based methods. The test has the potential to make high-quality PFAS monitoring more accessible, particularly for regional areas and developing nations.
Researchers at UT MD Anderson Cancer Center have made significant advancements in targeted therapy treatments for advanced lung cancer and early-stage classical Hodgkin lymphoma. The studies showcase high response rates with novel combination therapies and a new understanding of how an enzyme affects infertility and cancer progression.
Researchers at KTH Royal Institute of Technology have found a new, potentially more energy-efficient way to transmit information in electronic systems. By twisting two layers of certain atom-thin magnetic materials, they can generate and control magnetic signals without relying on electrical currents.
The Dunedin Study successfully completed its age 52 data collection phase with 92% of participants still involved. The study, following the lives of 1,037 babies born in 1972-73, has provided valuable insights into human health and development.
A new virtual reality intervention improved interactions between autistic teens and adults with law enforcement officers, reducing fidgeting and increasing positive behavior. The study showed significant improvements in the virtual reality group compared to a video modeling intervention.
The UK-led OpenBind initiative has released its first publicly available dataset and predictive AI model, accelerating the discovery of new medicines using artificial intelligence. The release showcases high-quality, standardized experimental data and a trained predictive model, enabling researchers worldwide to drive the next generati...
Researchers engineer bacterial vesicles into multifunctional tools that can kill pathogens, boost vaccines, and deliver targeted therapies. Engineered BEVs address key limitations of existing therapies, including improving vaccine responses and antibiotic delivery.
Researchers discovered over 400 proteins with modified states affecting drug binding, including KRAS and NPC2. PTMs may influence therapy selection and combination, offering new opportunities for targeted treatments. The study could reshape cancer treatment and lead to more effective therapies.
A new study from Edith Cowan University found that first-time parents are navigating a flood of conflicting advice on screen time, with many falling back on outdated rules due to uncertainty. The research suggests that fear-based messaging around children's screen use is fuelling guilt and anxiety among parents.
A new study mapped the internal structures of 87 ray-finned species in three-dimensional detail, revealing a wide range of brain sizes and shapes. Environmental factors appear to drive this variation, with deep-sea fishes tending toward smaller brains relative to skull size.
Researchers found that a drying climate and lack of management led to intensified bushfires on Kangaroo Island between 5,000 and 2,000 years ago. The study provides context for managing the island's unique flora and fauna.
Researchers at Sultan Qaboos University developed a portable sensor for quick pathogen detection, overcoming limitations of conventional methods. The device can be used for field inspections, remote settings, and environmental monitoring, enabling personal, real-time testing.
Researchers from the University of Jyväskylä emphasize the importance of multiscale modeling in understanding and developing electrochemical processes. The study highlights the need for a thorough understanding of methods used and reactions studied, as computational tools can reliably model phenomena on different scales.
Dr. Aparna Bhaduri receives $750k Pershing Square Sohn Cancer Prize for her innovative glioblastoma research. Her advanced human organoid models reveal how tumors interact with the immune system and brain cells, driving tumor aggressiveness.
A new study found that stroke incidence is rising again, with higher rates in Black African and Black Caribbean populations, as well as those experiencing socioeconomic deprivation. The study highlights the need for targeted interventions to prevent strokes and address systemic inequalities.
A new study suggests that both very low and very high resting heart rates are associated with an increased risk of stroke. The research found a U-shaped pattern, with stroke risk lowest at heart rates of 60-69 bpm and highest at below 50 bpm or above 90 bpm.
A hantavirus cluster linked to a cruise ship has resulted in multiple severe cases and fatalities, emphasizing the importance of environmental controls, early detection, and clear communication. The incident highlights the need for robust sanitation, rodent control, and environmental monitoring practices in travel settings.
Researchers identified a protein from the quagga mussel that can stick to surfaces underwater without DOPA, a modified amino acid previously thought essential for adhesion. The findings could inform the design of future medical glues and anti-fouling technologies.
Teachers view AI as a tool to reduce workload, but worry it may erode social aspects of teaching. The study found that affluent schools are better equipped to integrate AI into their curriculum.
Patrick T. O'Gara, a master clinician and educator, will receive the TCT 2026 Career Achievement Award for his groundbreaking work in interventional cardiology. The award recognizes his clinical excellence, pioneering research, and mentorship of the next generation of physicians.
Researchers have discovered a biomarker for chemotherapy resistance in small cell lung cancer, which can help identify cells that become more invasive and lead to treatment resistance. Targeting these cells with YAP1 may be a possible strategy to improve patient outcomes.
A new study found that girls struggle to master AI due to low confidence and limited institutional support. To overcome this, schools should provide more female role models and create a supportive classroom environment.
Wayde Marsh, a political science professor at the University of Tennessee, has been awarded a $200,000 stipend to study the role of religious institutions in supporting communities after trauma. His research aims to build a database of historical events and explore how leaders' rhetoric affects political behavior.
Researchers at the University of Toronto have developed a new method to mature lab-grown heart cells, which exhibits greater structural organization and improved ability to contract. This advance could help create more reliable models for studying heart disease and testing new drugs.
Researchers developed a framework to study the impact of genetic variants on neurodevelopmental disorders. By analyzing induced pluripotent stem cells, they found that genetic background can lead to different clinical outcomes in individuals with the same deletion on chromosome 16.
A Baylor anthropologist's research reveals that hunter-gatherer societies maintain equality through social pressure and demand sharing, rather than altruism. The study, which tested the Hadza population in Tanzania, found that people were more likely to take resources than give them when they had more.
A new study reveals that 3.4 billion years ago, life on Earth used biochemical processes reliant on the metal molybdenum, which is scarce in its environment. Molybdenum speeds up chemical reactions essential for life, enabling organisms to survive without it, but at a slower rate.
A new study from Drexel University finds that decentralized stormwater management strategies can significantly reduce flooding volumes, with a 11-13% decrease. These efforts include rain barrels, cisterns and water-efficient fixtures, which help minimize the amount of water flowing into sewer systems.
Researchers at University of Toronto Engineering have developed a non-toxic coating made of polydimethylsiloxane (PDMS) that prevents proteins from sticking to surfaces. The liquidlike surface covered in PDMS bristles resisted protein adhesion even better than polyfluoroalkyl substances (PFAS).
The University of Utah and National Laboratory of the Rockies have signed a three-year MOU to strengthen the US energy system. The partnership enables research on urgent national security and energy priorities, including water security, critical minerals, and advanced manufacturing.
A study published by National Jewish Health found significant gaps in understanding occupational risks for mineral non-coal miners, with silicosis affecting a substantial portion of the global mining workforce. The research emphasizes the importance of ongoing exposure monitoring and medical surveillance to reduce disease rates.
A survey of 32,419 adults across 18 countries found that people with poor mental health reported worse care quality and less confidence in the healthcare system. The study highlights a need for healthcare systems to rethink how they serve this growing population with more complex needs.
A new study by Yale University researchers suggests that Louisiana is facing an inevitable shoreline retreat due to climate change, prompting the need for managed relocation. The state has a limited time frame to plan and implement effective relocation strategies that prioritize social welfare and environmental quality.
Researchers detected airborne virus, wastewater contamination, and asymptomatic cows on infected dairy farms, suggesting multiple modes of transmission. This finding highlights the need for mitigation strategies to reduce viral spread in herds and humans.
A study published in PLOS Medicine found that only 43% of menu items at the UK's highest-grossing restaurant chains met all voluntary targets for sugar, salt, and calorie reduction. This suggests that stricter regulation may be needed to improve the nutritional quality of out-of-home food.
Researchers uncover role of glia in ALS pathogenesis, finding altered functioning of TDP-43 protein and MYC factor responsible for abnormality. The study provides new anchors to understand clinical heterogeneity of ALS and suggests potential biomarkers for diagnosis and monitoring.
A Concordia-designed simulator models hemodynamics in reduced gravity environments, revealing key differences in blood flow and pressure patterns. The system successfully reproduced effective CPR on Earth and generated consistent blood flow under both normal and hypogravity conditions.
Researchers at Florida International University have discovered that sargassum seaweed can serve as a valuable ingredient in everyday foods due to its high content of alginate. The study shows extraction yields of roughly 45% and demonstrates the potential for sargassum as an alternative source to traditionally harvested seaweeds.
The merger will enable significant operating efficiencies and combined scale with Project MUSE, while maintaining BioOne's flagship aggregation of bioscience research journals as a discrete product within Hopkins Press. The integration is expected to expand services, shared infrastructure, and sustain revenue for the nonprofit community.
A new study from the University of Pennsylvania School of Nursing found that safer nurse staffing levels in Pennsylvania hospitals could prevent up to 3,040 hospital deaths annually and reduce costs by an estimated $239 million. The study analyzed data from over 547,000 patients and nearly 2,800 nurses across 132 hospitals statewide.
A new autonomous laboratory named PoLARIS has identified brighter, lead-free light-emitting nanomaterials in just 12 hours. By analyzing the optical properties and adjusting variables, PoLARIS has improved the brightness of these materials, enabling faster discovery of safer optical nanoplatelets for various applications.
Researchers found that Demodex mite overgrowth and heightened innate immune activity are hallmark drivers of rosacea but not sensitive skin syndrome. Sensitive skin syndrome has its own unique mechanisms, characterized by distinct biomarkers such as reduced cathelicidin and dermcidin levels.
Researchers developed a physics-inspired framework to predict how accents and dialects change over time and location. The model demonstrates sweeping linguistic shifts across the US during the 20th century and shows that language may be law-like, with hidden statistical forces shaping human communication.
Sanford Burnham Prebys receives a $5 million gift from Andrew Viterbi to advance its Center for Data Science and Artificial Intelligence. The center is exploring raw or untapped data to uncover patterns and insights that can inform scientists and clinicians.
Scientists have measured the atmosphere of the mini-Neptune, revealing a heavy composition with water vapor, carbon dioxide, and sulfur dioxide. The findings suggest that both planets formed far from their host star, then were drawn inward through a gradual process, preserving their atmospheres.
A new white paper by Dr. Jar'Mel Taylor examines how school systems can better equip educators to respond when students show signs of distress, conflict or harm. The paper proposes a trauma-informed bystander intervention model to strengthen safety and belonging in K-12 schools.
Regular physical activity is essential for mitigating the regain of lost weight after discontinuing GLP-1 medications. Exercise has complementary effects beyond energy balance, including improved insulin sensitivity and increased fat oxidation. Clinicians must develop individualized strategies to improve exercise adherence.
Researchers at Mass General Brigham found that advanced footwear technology improves running performance in elite distance runners, but also causes subtle changes in running mechanics linked to bone stress injuries. Rotating shoes and gradually adapting to AFT may help reduce potential injury risk while optimizing performance.
Ordinary adhesive tape stores a sequence of multiple memories with tunable strength, allowing for simple mechanical calculations. Researchers developed an automated device to create these memories by peeling the tape past designated distances.
Researchers used AI to design new molecules for disinfectants, leveraging a dataset of hundreds of existing quaternary ammonium compounds. The approach yielded 11 promising compounds with activity against antimicrobial-resistant bacteria, offering a potential solution to the growing threat of 'superbugs'.
A $3.1 million R01 grant will fund research exploring how targeted therapy can strengthen bones in children with osteogenesis imperfecta while still in the womb. The goal is to develop a prenatal drug therapy that improves outcomes for both mothers and children.
Researchers discovered that fungal effector proteins evolved from ancient antimicrobial proteins to weaken host immune systems and manipulate the surrounding microbiome. These findings provide new insights into how fungi attack both hosts and beneficial microorganisms, with potential applications in agriculture and medicine.
The Colorado Asthma-Friendly Schools initiative recognizes 221 schools for their comprehensive asthma management and student health efforts. Over 120,000 students have benefited from the implementation of evidence-based asthma management practices at school.
Researchers explore the potential of black phosphorus for high-capacity alkali metal-ion batteries, overcoming stability and interfacial challenges through engineered architectures. Scalable synthesis, composite engineering, and interfacial regulation hold key to practical deployment.
A systematic review finds that a combination of aerobic and muscle-strengthening exercises significantly improves cardiovascular outcomes in healthy adults. The optimal exercise duration is found to be between 40-60 minutes per week, with evening aerobic exercise showing greater health benefits.
The study found that researchers value the university's commitment to diversity and anti-discrimination measures and are broadly satisfied with their working conditions. However, respondents identified areas for improvement, including the need for structured institutional support and clear procedures to prevent discrimination. The find...
A study by Cranfield University found that almost all plant-based meat alternatives and beverages in the UK contained at least one mycotoxin, with multiple products containing more than one. The research highlights the need for effective mycotoxin management integrated within food safety standards.
A new study reveals that soil carbon residence time governs riverine dissolved organic matter's age, with climate, hydrology, and soil processes controlling carbon cycling in rivers. The research provides a high-resolution global atlas of riverine DOC, showing that ancient carbon sources are locally important but modern terrestrial org...
A new study has identified seven distinct subphenotypes of pneumonia based on pulmonary histopathology, revealing different patterns of inflammation and damage in the lungs. These findings suggest a foundation for developing targeted therapies for patients with varying disease profiles.
A new AI system, SPARK, enables autonomous scientific discovery in cancer pathology by generating biological hypotheses and translating them into analytical tools. The system identifies clinically relevant tissue markers linked to disease course, treatment response, and tumour progression.
University of Missouri researchers developed an irrigation strategy that allows farmers to conserve water while maintaining crop quality. By tailoring water amounts based on plant growth stages, farmers can reduce water usage and costs.
The American College of Lifestyle Medicine released a new toolkit to help clinicians integrate lifestyle interventions with obesity medications. The toolkit provides practical guidance and patient education across the full course of medication use, addressing concerns about the lack of adequate lifestyle counseling. It aims to align ra...
Researchers at University of Leeds discover how platelet myosin is normally kept inactive, but genetic mutations push it out of balance leading to disease. This breakthrough sheds light on the role of platelet myosin in blood clotting and shedding new hope for treating bleeding disorders.
A new study by Charles Darwin University and BirdLife International estimates that fewer than 500 Timor green pigeons remain in the wild, with the species thought to be functionally extinct in Indonesia. The authors urge governments, conservation organizations, and local communities to take urgent action to save the species.
A new study reveals that carnivorous plants like pitcher plants provide a vital source of nutrient-rich nectar to wasps, benefiting both parties. This interaction may be more than just predator-prey, as the plants and wasps work together for mutual benefit.
Researchers developed a microfluidic spray drying technology to rapidly synthesize high-phase-purity HE-NVPF cathode materials. The new method allows for efficient and scalable energy storage solutions with superior performance.
Complex systems exhibit emergent properties due to water's unique polarity, enabling DNA to store information and proteins to adopt specific structures. This order forms the basis for complex molecules to develop unpredictable properties, driving the evolution of life.
A comprehensive watermelon super-pangenome has been established to understand genotypic differences contributing to phenotypic variation in watermelon. This resource integrates 138 genomes from wild and cultivated watermelons, revealing evolutionary relationships and genomic prediction capabilities.
A majority of Americans, 60%, are concerned about high blood pressure, with nearly half having the condition. A new survey found that 65% are willing to try a plant-based diet to manage their blood pressure. Plant-based foods like fruits, veggies, beans, and whole grains can help maintain healthy blood pressure.
A study of 1,152 people found that humans cooperate more with fair AI than with AI that is helpful or selfish. Fairness was the key to cooperation, not unconditional niceness. The researchers suggest that humans respond best to AI that can navigate social rules and expectations in a believable way.
Research suggests that tailoring weight loss strategies to individual patients can help preserve lean mass and reduce the risk of regaining weight. The study found that a specific gut hormone, FGF15, plays a key role in this process.
Researchers used a technique called theoretical morphospace to analyze bird wings, finding that many species have wing shapes ill-suited for their flight performance. Penguins and hummingbirds stand out as exceptions, having evolved optimally shaped wings for their specialized styles of movement.
A phase 2 human clinical trial of a hookworm antigen has shown effective in limiting the intensity of infection, paving the way for a vaccine. The study found that vaccination with Na-GST-1 reduced the severity of infection in participants.
The rise of consumer-facing health AI assistants is transforming healthcare access, offering users personalized medical workspaces and real-time lab result interpretation. However, concerns around data privacy and the risk of misdiagnosis highlight the need for caution in this rapidly evolving landscape.
This study reveals Yanghe Decoction's anti-tumor effects on osteosarcoma cells by modulating the PI3K/AKT and p38 MAPK pathways, inducing ROS-mediated mitochondrial dysfunction. YHD also inhibits tumor growth and metastasis in orthotopic OS mouse models.
A study by TGen and City of Hope found a significant correlation between tumor splicing burden and clinical response to treatment for metastatic renal cell carcinoma. Patients with high splicing burden showed signs of robust immune activation, suggesting the body may be primed to attack cancer cells.
Researchers studied how meltwater from one iceberg impacts its neighbor's melting rate. They found that the gap between icebergs determines their final shape and melt rate., Iceberg clusters may be less prone to melting than isolated icebergs due to the protective effect of meltwater.
A new €2.5 million project aims to better understand why people with inherited mitochondrial disorders are more vulnerable to severe infections, which can cause profound neurological impairment and a range of other complications. The project will investigate how harmful mutations in mitochondrial DNA alter the behavior of immune cells.
Researchers from Universitat Rovira i Virgili developed an AI tool called CoCoGraph that can generate realistic molecules complying with chemistry laws. The system uses a diffusion model to create plausible structures, resulting in 100% chemically valid molecules, and has been found to be more realistic than other state-of-the-art models.
Researchers found that psilocybin causes temporary shifts in brain entropy, leading to increased insight and emotional self-awareness. This correlates with improved well-being and cognitive flexibility, suggesting the psychedelic trip is key to its therapeutic effects.
A new study sheds light on the extinction of ancient ocean creatures, revealing that nautiloids survived due to their larger eggs and slower metabolic rates. The findings contradict previous hypotheses, suggesting that egg size was a key factor in their survival.
A new study found that natural selection favored Indigenous Andeans with high numbers of salivary amylase genes, leading to a higher frequency of these genes in the population. This suggests that potatoes played a crucial role in shaping the genetic makeup of this population.
A study published in Radiology used AI to analyze whole-body MRI scans from over 66,000 participants, revealing that skeletal muscle quality is a strong predictor of diabetes, major cardiovascular events, and mortality. The researchers also found that high visceral fat and low skeletal muscle were associated with increased risks of the...
Researchers developed a hand-held device to differentiate tumors from healthy tissue using mechanical properties, reducing the need for future surgeries and delayed treatments. The wireless probe can aid surgeons in precise tumor removal during breast-conserving surgery.
A research team led by Professor Denver Li Danfeng has discovered a magnetic-field-induced 're-entrant' superconductivity phenomenon in infinite-layer nickelate superconductors. This finding challenges the conventional understanding that magnetic fields suppress superconductivity and opens up new directions for exploring unconventional...
Researchers develop quantum algorithms to simulate polymer degradation caused by UV radiation, using industrially relevant aircraft coatings as an example. The goal is to optimize surface coatings for various industries, improving safety and reducing costs.
Indigenous people of the Andes have a genetic adaptation that allows them to digest starch more effectively due to their history of potato cultivation. Those with higher numbers of salivary amylase genes had an evolutionary advantage, resulting in an average of 10 copies of the gene in modern-day Peruvian Andeans.
A global study finds that regions with long-term isolation exhibit greater linguistic diversity despite lower genetic diversity. This dynamic helps preserve a wider range of language structures and grammar organization.
Researchers used MRI to analyze muscle composition in 11,348 participants and found that higher intermuscular fat and lower muscle mass were associated with increased cardiometabolic risk factors. Lean muscle mass was only protective against these risks in men, while women's muscle mass declined after age 40.
The study reveals that human TERT is only compatible with non-human primate cells, while other species show limited or no telomere lengthening. This highlights the importance of using suitable preclinical models for telomerase-based therapies.
A study reveals how a tropical tree genus evolved extraordinary photosynthetic strategies, including CAM, through genome duplication and genetic rearrangement. This diversity enables the trees to adapt to different ecological niches, making them ideal models for climate-resilient crops.
Research shows that diverse boards with members from various backgrounds bring new perspectives, strengthen oversight, and reduce aggressive tax avoidance. This leads to more questioning, debate, and closer scrutiny of management decisions, ultimately resulting in more responsible tax behavior.
Researchers discovered CLCA4 suppresses CSC properties and enhances anti-PD-1 immunotherapy, halting tumor growth and immune suppression in colorectal cancer. CLCA4 overexpression also reshaped the tumor immune microenvironment, sensitizing tumors to anti-PD-1 therapy.
A new study from the University of Surrey shows that firms celebrated for strong financial performance may actually be inefficient when environmental impact is included. The research developed a new way to measure sustainable corporate efficiency, combining traditional financial metrics with environmental data.
Researchers developed a unified topological framework to characterize complex boundary states in Floquet crystals, predicting the existence and type of various topological boundary states. The framework uses three complementary one-dimensional winding numbers to unify the description of multiple boundary orders.
The study found that most 988 Lifeline centers struggle to find resources for full-time staffing, posing risks to staff well-being and service quality. Critical financing and operational strategies will be needed to support recruitment and retention to sustain high-quality 988 Lifeline services.
A new study published in Genes & Diseases journal reveals that lncRNA ROLLCSC promotes ferroptosis resistance and metastasis in lung cancer by regulating lipid metabolism. The researchers identified ROLLCSC as a therapeutic target, suggesting potential treatments for advanced lung adenocarcinoma.
Researchers identified a unique metabolic fingerprint in the hearts of patients with heart failure with preserved ejection fraction (HFpEF) and obesity. The study reveals disrupted glucose metabolism and accumulated metabolic products, which are linked to structural changes in the heart and disease severity.
Research reveals a causal link between alcohol consumption and epilepsy risk via neutrophil extracellular trap (NET) formation. MPO inhibition shows promise in reducing seizure susceptibility.
A retrospective study found lower in-hospital mortality and emergency department use within 30 days of discharge for Medicare beneficiaries undergoing hospital at home compared to traditional inpatient care. However, hospital readmissions within 30 days showed no significant difference between the two approaches.
High-powered lasers can vaporize a solid target, creating plasma that rapidly expands and generates strong magnetic fields. The team derived a simple threshold criterion to predict plasma magnetization for given laser and target parameters.
Dr. Lisa M. Satlin, a renowned pediatrician-scientist, has been awarded the ASPN Founders' Award for her lifetime contributions to pediatric nephrology through research, education, and clinical care. She has advanced understanding of kidney function and development, with significant implications for hypertension and kidney disease.
J. Craig Venter's pioneering work in expressed sequence tags revolutionized brain-expressed genes identification, while his synthetic cells paved the way for synthetic biology as a working discipline. His legacy has reshaped our understanding of genomes and their functions.
A University of East London study found that creative, practice-based assessments improved engagement and eliminated disparities in attainment linked to ethnicity. Students from minoritised backgrounds achieved high pass rates and degrees with traditional exams replaced by authentic assessments.
A review from Florida Atlantic University links obesity to Alzheimer's disease through disruptions in metabolism, highlighting the importance of mitochondrial function and gut-brain axis balance. Early detection and whole-body prevention may become possible through monitoring metabolic health.
A recent study found that over 37% of Americans have experienced a political breakup with friends, family members, or romantic partners. The research highlights the negative consequences of political polarization on interpersonal relationships and individual well-being.
Genomic Press launches Brain Health, a new peer-reviewed journal dedicated to the science of lifelong brain resilience, featuring research on glial plasticity and recovery from depression. The inaugural issue explores the intersection of fields including cognitive reserve, sleep, aging biology, nutritional psychiatry, and social sciences.
Researchers found that treated wastewater can safely recharge coastal aquifers, stabilizing water supplies. However, higher-quality treated wastewater is needed to minimize impacts on groundwater quality.
Research finds GADD45B induces MST1 expression by promoting DNA demethylation, exacerbating apoptosis and intestinal injury in I/R. GADD45B/TET1/MST1 axis may represent a viable therapeutic strategy for I/R injury.
A recent analysis found that GLP-1 prescriptions have grown exponentially, while bariatric surgery procedures have declined in recent years. The study revealed that over 90% of patients with severe obesity receive no treatment, highlighting the need for increased access to weight-loss therapies.
Researchers at Mass General Brigham developed an ultrasensitive test to detect abnormal clumps of TDP-43 protein in cerebrospinal fluid, a biomarker for specific form of dementia called FTLD-TDP. The test shows promise in diagnosing patients with the correct pathology and tracking disease progression.
Patients treated with GLP-1 drugs before surgery lost more weight than those who went directly to surgery, with total weight loss increasing to over 25% after gastric bypass and 20% after sleeve gastrectomy.
The number of metabolic and bariatric surgery procedures in the US declined by over 20% between 2023 and 2024, falling below 200,000 for the first time since 2020. The decline is attributed to rising obesity rates and increased use of GLP-1 medications, with significant shifts seen in the types of operations being performed.
New data show that over 50% of patients with obesity and CKD experienced a significant reduction in kidney failure risk, as well as a nearly 75% drop in mortality rate after undergoing bariatric surgery. This study highlights the transformative impact of metabolic and bariatric surgery on chronic disease outcomes.
A study published in the Journal of Nutrition found that moderate egg consumption is associated with a lower risk of Alzheimer's disease. Researchers discovered that eating one egg per day for at least five days a week reduces the risk of Alzheimer's by up to 27%.
A real-world analysis of over 90,000 patients with obesity and type 2 diabetes reveals that metabolic and bariatric surgery is the more affordable treatment option compared to GLP-1 drugs. Total costs for GLP-1 therapy were $17,000 more than sleeve gastrectomy and $7,200 more than gastric bypass after two years.
A new tool detects duplicate peer reviews, addressing research integrity concerns and strengthening the peer review process. The Duplicate Review Checker identifies problematic patterns in reviewer reports, enabling early interventions to safeguard manuscript assessments.
The report highlights a driven workforce despite rising pressures, with 83% of nurses citing purpose as a key motivator. Practical considerations like flexibility and job security are increasingly important for nurses evaluating their future.
Researchers at TUM develop NTVE, a process that uses virus-like particles to shuttle messenger RNA out of living cells, allowing for repeated sampling and analysis. This enables precise monitoring of stem cell development and potential applications in cell therapies and tumor research.
A new study by the University of Southampton reveals that an imbalance of nutrients in seawater can cause coral disease, potentially more so than heat stress. The research found that 88% of Black Band Disease incidents occurred in regions with highly imbalanced nutrient ratios.
A study redefines continental evolution by identifying relamination as a key mechanism shaping continents over billions of years. This process explains the origin of certain magmas and offers new insights into post-collisional magmatism, resulting in the formation of large granitic batholiths.
The report outlines risk scenarios on Earth, at sea, and in space, analyzing the fragility of interconnected digital systems. Experts call for coordinated action between countries to improve digital resilience and protect essential services.
A new study finds that rock dust can improve soil fertility and yields in cacao systems, supporting local communities. The research suggests that enhanced rock weathering could help reconnect fragmented rainforests, leading to increased carbon sequestration.
Three young scientists in Israel have been awarded the prestigious Blavatnik Awards for their innovative research in chemistry, cancer biology, and astrophysics. Sergey Semenov, Uri Ben-David, and Paz Beniamini will each receive US$100,000 to advance their projects on complex materials, cancer treatments, and extreme cosmic events.
Researchers identified two main groups and five subgroups of Parkinson's disease, providing a framework for more targeted therapies. The study reveals that different genetic forms naturally cluster into distinct subtypes, allowing for subgroup-specific drugs to be developed.
A new species of moth, Pyralis papaleonei, has been discovered in the White Mountains of Crete, Greece, showcasing its striking purple forewings and orange-golden patch. The discovery underscores the urgent need to protect sensitive habitats and highlights the importance of scientific research in biodiversity conservation.
A new study found that updated alcohol warning labels, including those highlighting cancer risk, can better motivate consumers to cut back on drinking. The study used a nationally representative sample of adults and found that the new labels outperformed the current U.S. warning label in encouraging participants to drink less.
A study finds microplastics in the human brain associated with increased risk of stroke and dementia. Apheresis, a medical treatment, is proposed as a potential removal method for microplastics from the body.
Gonçalo Cotovio uses lesion network mapping to identify the circuits responsible for psychiatric symptoms, aiming to develop personalized brain stimulation treatments. His work has produced striking findings in mania and obsessive-compulsive disorder, with ambitions to extend to disordered feeding behavior.
Dr. Dilek Colak's journey began with a childhood observation of a boy with mental illness, which inspired her to pursue a career in neuroscience. Her current work focuses on understanding autism and schizophrenia through the study of human brain organoids.
Researchers uncover evidence of recurrent high-mountain occupation and systematic exploitation of copper-rich minerals in Cova 338. The site provides new insights into the role of high mountain environments in Pyrenean prehistoric societies.
Researchers have developed a new combination therapy that shows promising results in treating patients with Crohn's disease and ulcerative colitis. The treatment, which combines two mechanisms of action, has been shown to improve clinical remission rates by more than 20 percentage points compared to existing therapies.
Researchers have developed a new class of biodegradable, all-metal microrobots that can penetrate tissue and deliver medications without causing damage. These microrobots demonstrate both strength and safety in testing on mice, paving the way for potential applications in drug delivery and biopsy procedures.
Researchers have developed a simplified mathematical model of learning in neural networks, shedding new light on how these systems produce their responses. The toy model, inspired by physics principles, captures key features of complex systems and offers insights into the surprising efficiency and stability of modern AI systems.
Archaeologists uncover evidence of ancient copper smelting in a mountain cave, spanning over 2,000 years. Human remains and lost jewelry suggest the site may have been a burial ground, while fire played a deliberate role in processing the green mineral fragments.