Researchers developed a new framework to analyze historical weather data and found a significant reduction in solar radiation in central Japan during the summer of 1836, leading to higher rice prices. The study provides a more detailed understanding of how climate fluctuations impacted society.
A systematic review of point-of-care testing found that rapid tests improve people's understanding of their condition, increase confidence in self-management, and motivate lifestyle changes. This leads to better medication adherence and improved clinical markers, ultimately reducing the risk of serious complications.
A perspective paper on digital transportation explores its basic theories and proposed research directions. The author highlights the need for a comprehensive theoretical framework to guide the development of modern vehicles and digital transformation of transportation infrastructure.
Research reveals that pedestrians in Phnom Penh prefer shorter, simpler routes with fewer turns due to factors like path efficiency, street vitality, and perceived comfort. The study also found that high-traffic streets are often preferred over crowded footpaths, reflecting a desire for clarity, predictability, and ease of movement.
The updated algorithm incorporates evidence from multiple randomised clinical trials, highlighting the strength of tirzepatide for weight loss and semaglutide for liver disease management. The new guidance also recommends semaglutide for metabolic dysfunction-associated steatohepatitis remission.
A new malaria vaccine has demonstrated strong protection against the disease, inhibiting transmission by mosquitoes and requiring no refrigeration. The vaccine targets two critical stages of the malaria parasite's life cycle, reducing infection rates by up to 80%.
A new probabilistic model developed by Kyoto University shows that about 50 to 60 percent of the variance in typhoon intensity can be explained by spatial ocean surface temperature (SST) patterns and increasing average SST due to climate change.
Duke-NUS Medical School has expanded its Pathways to Medicine program to welcome students from Nanyang Technological University and NUS College. This move allows students to explore diverse academic interests before joining medical school, with conditional admissions to Duke-NUS' Doctor of Medicine program upon graduation.
Researchers at Saitama University have developed cyanobacterial strains that produce free fatty acids and secrete them into the culture medium, enabling efficient production of sustainable aviation fuel and diesel fuel alternatives. The extracellular production strategy reduces energy consumption and minimizes residual cellular waste.
Researchers found that bird predators adjust their attacks to avoid triggering strong collective waves from sulphur mollies, but also exploit weak points in the group's defense. The fish, in turn, seem to 'remember' previous predator attacks, leading to stronger responses when attacked again.
Researchers from the LIGO–Virgo–KAGRA Collaboration demonstrate how Astro Calibration technique improves signal processing by leveraging astrophysical models and comparison to predicted signals. This enhances detection of cosmic phenomena like black hole mergers, refining estimates of masses, spins, distance, and location.
Aerobic exercise consistently demonstrates robust reductions in ambulatory blood pressure, while combined exercise and HIIT show promising results. The findings suggest that resistance training should be viewed as a complementary strategy to lower high blood pressure.
Research reveals that persistent upper gut symptoms experienced by people with hEDS are due to heightened sensitivity and altered signalling between the gut and brain, rather than structural abnormalities. The findings highlight the need for a comprehensive biopsychosocial approach to care.
A new study published in Nature Mental Health found that using cannabis and tobacco together significantly increases the risk of developing psychotic disorders like schizophrenia among those considered high risk. The study analyzed data from over 1,000 participants and found that co-use was associated with a nearly threefold increased ...
A new UCL study reveals that heavy caring responsibilities can accelerate mental decline in people aged 50 and over. Lighter caring duties, on the other hand, can be beneficial to mental abilities. The researchers found that intensive carers are most at risk and need stronger support.
A study found associations between mothers' occupations held before conception and ASD diagnosis in offspring, particularly in ground transportation, public administration, and military jobs. The researchers suggest that exposure to toxins and combustion products, as well as high stress at work, may contribute to neurodevelopmental risk.
A PSU-led research team has developed a novel chemical compound, T111, that shows promise for treating and preventing malaria. The compound targets all three major life-cycle stages of the malaria parasite, making it a strong candidate for a single-encounter radical cure.
The AI framework uses environmental and hydrometeorological data to provide early warnings of E. coli contamination risk, giving communities a window to act before health risks emerge. It identified unsafe conditions with approximately 85% accuracy, demonstrating its potential to offer earlier warnings.
A new analysis of police data reveals that one in 10 missing incidents among people with dementia results in serious harm. The study highlights the need for preventative action to keep people with dementia safe and finds that older age, night disappearances, and longer durations of absence are risk factors for harm.
The UN is highlighting the potential of artificial intelligence (AI) and digital innovation to create smarter, more resilient and sustainable cities. The International Telecommunication Union has released a Call to Action for Humanity, identifying five strategic priorities to address urban challenges.
New research finds lift capacity signs across Europe are outdated, failing to reflect current obesity trends. The study suggests that modernizing these signs is crucial for maintaining safety and comfort, while also acknowledging limitations in the investigation.
Patients on tirzepatide at maximum dose have seven times higher odds of maintaining weight loss compared to those who stop treatment. Those on the lower 5mg dose have four times higher odds, according to a new study published in The Lancet.
New research finds that participants in the ATTAIN-MAINTAIN trial maintained a significant percentage of weight loss when switched from injectable tirzepatide or semaglutide to daily oral orforglipron treatment. The study shows that nearly all weight loss achieved on injectable therapies can be maintained by switching to oral therapies.
Researchers identified GPNMB as a key molecule driving brain cell damage in Parkinson's disease. Blocking this protein with antibodies may help slow disease progression by interrupting the spread of toxic brain proteins.
Dr. Gianrico Farrugia will complete his tenure as Mayo Clinic President and CEO in December, leaving a legacy of strategic advancement and innovation. The institution has accelerated disease cures, connected people with data, and transformed healthcare through its AI-enabled care transformation platform.
Researchers found that action-based friction, which required users to search for existing image resources, increased users' ecological responsibility in their AI use. The study also showed that cue-based friction, such as persuasive messaging about AI's environmental impacts, did not tend to affect users' intentions to use AI responsibly.
A new University of Michigan study highlights a distinct rural-urban gap in adolescent health. Teens in poor rural neighborhoods are more likely to smoke cigarettes than their peers in less disadvantaged rural areas, suggesting that urban areas may offer different social influences.
Scientists have identified the fundamental cause of performance decline in lithium metal batteries, which can lead to improved driving range and longer battery lifespan. The research team discovered that 'dead lithium' - electrically disconnected lithium - forms when irregular lithium deposition or stripping occurs, posing safety risks.
A recent study from Texas A&M University suggests that irregular sleep patterns may increase the risk of dementia. The research team, led by Karienn Souza, found that chronically disrupted circadian rhythms can lead to activated microglia, which can contribute to inflammation and damage in the brain. The team plans to test a new therap...
Research by Dr. Hanim Diktas at Pennington Biomedical Research Center shows that combining GLP-1 receptor agonists with behavioral intervention leads to a greater reduction in 'food noise', a persistent thought about food disrupting daily life and healthy behaviors. The study found significant decreases in food noise for participants u...
A new reactor design produced up to 6.9 liters of methane per liter of reactor volume per day, achieving coulombic efficiencies above 95% in laboratory tests. The system efficiently converts carbon dioxide and renewable electricity into methane through a hydrogen-mediated pathway.
Researchers at Texas A&M University developed electrochromic hyperspectral embedding (ECHSE) to integrate intelligence into optical sensors. This technology enables faster data analysis and reduces energy consumption for applications such as surgical robots and space exploration.
A new study challenges the hypothesis that climate change will lead to massive ag pest populations, suggesting a more complex relationship between warming and pest dynamics. The research found that some species thrive in warmer climates while others decline or show no response.
A new study by Lund University researchers identifies knowledge gaps and proposes tools to analyze the risks of extreme weather on birds. Birds are vulnerable due to their diurnal nature and lack of burrowing capabilities, making them more susceptible to heatwaves.
A new study reveals a correlation between body weight and gut microbiota composition, which can lead to gastrointestinal diseases. However, genetics also play a role in shaping the gut microbiome.
Researchers found bacteria thriving in fog droplets, breaking down pollutants like formaldehyde. The discovery suggests fog is a temporary water habitat for microbes that clean the air we breathe. Further studies are needed to understand the impact on drinking water and weather forecasting.
A new inspection workflow using AI-assisted review tools is being implemented at Sandia National Laboratories to speed up inspections and catch tiny defects earlier. The system will use high-throughput imaging systems to scan ceramic billets, reducing the need for manual microscopes and training operators.
Researchers found that people with depression experience reduced desire for food rewards during anticipation, but not during consumption. The study suggests that anhedonia in depression is characterized by altered expectation and motivational processes, which may be targeted in therapeutic approaches.
A team of international researchers will investigate the underlying biology of psychiatric and cognitive symptoms in Parkinson's disease, with a focus on depression, anxiety, and other non-motor symptoms. The study aims to improve diagnosis and treatment of these symptoms, which are common but poorly understood in the disease.
Researchers at Boise State University have developed a portable device capable of detecting PFAS in water samples in real-time and at trace levels. The ENVIR-OGT technology uses specialized transistors combined with machine learning to detect PFAS chemicals rapidly and accurately, directly at the point of sampling.
A new study warns that NHS surgery backlogs cannot be fixed solely by hiring more staff, citing staff sickness and administrative issues as major contributors. The research found that elective surgery waiting lists rose significantly between 2013 and 2024, with staff sickness absence having a consistent impact on completed cases.
Toloo Taghian, a UMass Chan Medical School assistant professor, has received a five-year, $3.2 million grant to develop a gene therapy for UBA5 disorder, a rare genetic disease that affects protein balance and leads to neurological impacts. The goal is to monitor disease progression and determine the efficacy of future clinical trials.
Researchers have developed a solid electrolyte technology for lithium metal batteries that operates stably even at low temperatures while reducing fire risks. The new electrolyte improves battery performance and enhances safety, making it suitable for commercialization.
Researchers developed a new CAR T cell therapy targeting U5 snRNP200 protein found on AML cells but not healthy blood cells. The approach harnesses antibodies discovered in patients who went into long-term remission after bone marrow transplant, proving effective against several types of leukemia.
The UC San Diego team developed an open-source digital twin platform called Tiny-Twin, which enables fast and realistic testing of applications over wireless networks. The platform allows researchers to test complete applications, such as video streaming, without needing specialized hardware or proprietary data.
A new study reveals that human childbirth is not the only mammalian experience with birth difficulties. Research shows that many other mammals, from domestic livestock to wild species, face similar complications and mortality rates. This challenges long-held assumptions about human childbirth being uniquely difficult.
A new study found that physically or psychologically aggressive parenting can disrupt a child's ability to regulate stress, leading to more external regulation as they age. Researchers observed 129 mother-child pairs and used heart rate monitoring to measure physiological regulation.
Researchers from Cornell Lab of Ornithology used networks of inexpensive microphones to track bird behavior, revealing complex patterns of risk assessment. Birds made subtle tradeoffs between defending territories and evading predators.
A study published in Anesthesiology found that icing can delay recovery time and prolong pain in some cases, highlighting a paradox between short-term pain relief and full recovery. The research suggests that anti-inflammatory strategies may be helpful but also interfere with biological processes required for full recovery.
Researchers at MIT and Europe create model predicting gravitational wave patterns from black holes in dark matter environments, detecting possible imprints on LVK data. The study offers a new way to screen gravitational-wave signals for hints of dark matter.
The Pittsburgh Institute for Neurodegenerative Diseases will investigate how environmental exposures cause neurodegeneration and develop methods to prevent or mitigate these exposures. The project aims to improve diagnostics and future therapies for Parkinson's disease, a condition characterized by heterogeneity across individuals.
Dr. Marcus Ruscetti receives the prize to study senescence and its impact on immune responses in cancer metastasis. The funding will help him develop novel treatments targeting senescent cells.
A University of Maine study found that US consumers are willing to pay more for lobster rolls made with ropeless fishing technology due to increased animal welfare concerns.
Researchers at USC have created complex lab-grown kidney models, known as human synthetic kidney organoids (hSKOs), which can mimic the filtering and urine-collecting functions of a real kidney. The team plans to study how these mini-kidney structures mature over time and test their ability to carry out key kidney functions.
Researchers used advanced imaging and spectroscopy techniques to analyze a decorative tian-tsui screen, revealing that different bird species and pigments were used to create unique colors. The study provides new insights into the complex phenomenon of structural color and its role in ancient Chinese art.
A new position statement from the Society of Interventional Radiology highlights the growing role of genicular artery embolization (GAE) in treating symptomatic knee osteoarthritis. GAE is a safe and durable joint-preserving intervention that targets inflammatory and neurovascular drivers of KOA-related pain.
Researchers developed AI models using electronic health records and electrocardiograms to identify individuals at elevated risk for sudden cardiac arrest. The combined EHR-EKG model correctly predicted 153 of 228 high-risk patients who experienced a cardiac arrest, bringing theoretical risk into focus.
The University of California San Diego has been awarded a $5 million renewal for its Faculty Institutional Recruitment for Sustainable Transformation (FIRST) program. The program enabled the institution to hire 12 new faculty in life sciences disciplines across campus, who have collectively brought in $16 million in new research grants.
Researchers develop deep learning surrogate for simulating nonlinear optical physics in ultrafast laser systems. The model accelerates simulation by orders of magnitude while maintaining high fidelity, and enables integration with experimental laser control systems.
Research from Rutgers University finds that absorbing real-world firearm content can be tied to depression and poor mental health outcomes among American adults. Higher levels of depression and more days of poor mental health were associated with frequent exposure to real-world firearm violence through media, such as social media and c...
Researchers have developed two new tools to study the molecular changes and intercellular dynamics of aging. IRISeq uses DNA barcodes to map tissue organization without a microscope, revealing inflammatory cellular neighborhoods in the aging brain.
Researchers are studying how individuals adapt to violently acquired spinal cord injuries using national longitudinal data and interviews with those affected. The study aims to provide insights into psychosocial factors influencing recovery and resilience among these survivors.
A real-world study highlights higher overall irAE incidence in lung cancer (61.0%) compared to GI tumor patients (47.9%). Skin toxicity is more frequent in GI tumors, while thyroid dysfunction prevails in lung cancer patients.
The researchers' hybrid system combines neuromorphic-inspired auto encoding and Fowler-Nordheim annealing to find the most efficient solution. This approach differs from classical computing methods and offers convergence guarantees, ensuring a solution will be found within a set timeframe.
The PrecisionView device enables clinicians to visualize both subcellular structures and underlying blood vessels across large tissue areas without invasive biopsies. It generates detailed maps of tissue areas spanning several square centimeters and displays results in real-time.
Researchers are working to overcome key obstacles in commercializing carbon waste gas into platform chemicals, including finding the optimal compression level and managing temperature. The US could be left behind if other countries invest heavily in this technology.
Parth Pathak is commercializing mmID, a novel Internet of Things solution that tracks accurately without batteries. The project aims to provide fast communication capabilities.
A Capital Medical University study reveals that intraoperative signal changes can predict vision loss during brain tumor surgery. Researchers found that a specific signal component, N75-P100, is strongly associated with postoperative visual outcomes.
Researchers at the Paul Scherrer Institute measured air quality near Zurich Airport, detecting high concentrations of ultrafine particles and lubricating oil emissions. The study confirms findings from other European airports and highlights the need for countermeasures to reduce emissions.
Research suggests that aging immune systems compromise the body's ability to control Mycobacterium tuberculosis during treatment with rifampicin and isoniazid. The study identified age-associated immune abnormalities linked to impaired bacterial clearance, including chronic inflammatory signaling and mitochondrial dysfunction.
A new study reviews key components of older adult surgical care, including delirium prevention and screening, fall prevention, and bowel regimens. The seven-component perioperative protocol is associated with improved outcomes, such as reduced complications and shorter hospital stays.
Soil animal communities exhibit greater trophic diversity in agricultural systems and tropical regions, driven by resource limitation and disturbance. This flexibility helps maintain soil functions but may reflect the loss of specialized species.
Liver injury occurs in 75-85% of dengue infections, mostly mild. Severe hepatitis and ALF are uncommon but have high mortality. Early recognition is crucial to guide referral to liver specialists and transplant teams.
A research team at Postech has developed a next-generation laser emission platform capable of precise color control under battery-level low voltage. The technology achieves ultra-high color purity and continuous spectral tunability within a single device, overcoming limitations of conventional display light sources.
Research found that people with obesity experience fewer pleasant emotions during exercise and are more likely driven by external motives. Positive emotional experiences and intrinsic motivational factors explain both physical activity levels and future exercise intentions.
Researchers used the Rational Inattention model to analyze large language models' hate speech classification performance, finding that it accurately predicts how their performance changes in different conditions. This analysis can help guide digital communities using LLMs for content moderation.
A cross-sectional study of over 76 million American children found that nearly 40% have had a family member criminally charged at some point during their childhood. Lower-level contact with the criminal justice system is associated with stigma, mental health struggles, and employment/educational disruptions, threatening children's well...
Dr. Ningshi Yao is awarded $628,260 by the NSF CAREER program to develop a unified framework for real-time scheduling and control in networked safety-critical systems. The project aims to address complex resource contention issues, enabling safe resource management for large-scale autonomous technologies.
The partnership aims to bridge the gap between fundamental research and real-world deployment of neuromorphic computing technologies. Key findings include the development of proof-of-concept applications, scalable solutions, and training programs for skills development in this rapidly emerging field.
A new worm model developed by Brown University researchers could play a key role in treating alternating hemiplegia of childhood, a disorder that causes paralysis in children. The genetically engineered C. elegans nematode model provides a fast and inexpensive way to evaluate potential drug treatments for AHC.
The alliance aims to address the diagnostic gap in rare diseases, leveraging genomics, AI, and technology. BGI Genomics is establishing a national-level rare disease diagnosis center with improved access across Southeast Asia.
The condition is recognized as a complex, multisystem disorder involving endocrine, metabolic, reproductive, dermatological, and psychological health. The new name, PMOS, is expected to reshape how the condition is diagnosed, treated, and researched globally.
Research finds estrogen plays a powerful role in regulating liver health, inflammation control, and energy processing, which become disrupted when levels decline. Restoring estrogen reverses many effects, suggesting targeting inflammatory pathways may prevent heart disease in women after menopause.
Researchers create conjugated polymer with bipyridine units that enhances water oxidation kinetics and charge separation, leading to high efficiency in H2O2 production. The strategy offers a promising route for sustainable chemical synthesis driven by solar energy.
Kuo-Chu Chang, a professor at George Mason University, has received funding for the 'PRECISION' project. The research focuses on developing AI-powered techniques to enhance supply chain resilience through predictive analytics and knowledge graph-based reasoning.
A first-in-human trial demonstrates the potential of implantable cytokine factories for treating ovarian cancer, showing a favorable safety profile and encouraging disease stabilization in patients. The therapy successfully activated key immune cells without expanding regulatory T cells, revealing a promising mechanism of action.
A study by UC Irvine researchers found that renewable electrolytic hydrogen produces its greatest societal value when applied to steelmaking, transoceanic shipping, and long-haul heavy-duty trucking. The study suggests that these sectors can benefit from the transition to hydrogen, often offsetting additional costs.
Researchers at MIT have developed a technique to create nanoscale features in hydrogel materials, shrinking them down to 100 nanometers or smaller. This allows for the creation of photonic devices that can manipulate visible light, enabling optical computing and potential applications in high-speed imaging and information processing.
Mingkui Wei, a George Mason University Associate Professor, is creating a new website for the Northern Virginia Vietnam Veterans Foundation to improve member services. The project received $15,000 from the Virginia Innovation Partnership Authority and will be completed by May 2027.
A study in Japan found that individuals with higher health literacy regarding gastric cancer and screening, those who perceived themselves to be at risk, and those who received encouragement from others exhibited stronger screening intentions. Concrete implementation intentions were also significantly linked to actual screening partici...
Long-term conservation tillage significantly alters soil microbial dynamics, increasing microbial abundance and reducing competition. Key taxa like Bradyrhizobium flourish under CT, while assembly of microbial communities shifts to stochastic processes with increasing soil depth.
Research highlights the interplay between circadian disruption and cardiovascular comorbidities, including cardio-cerebral, cardio-hepatic, and cardio-renal interactions. Chronotherapies show promise in re-entraining circadian rhythms, with potential applications for personalized treatment.
Researchers discovered a low dose of digoxin reduces heart failure-related deaths and hospitalizations by 19% and 25% respectively, making it an inexpensive and safe treatment option.
Researchers developed a comprehensive physical model explaining how temperature affects the fundamental characteristics of emitted light, including color, intensity, and randomness. The discovery opens new possibilities for designing advanced light sources, optical sensors, and thermally based photonic systems.
Researchers tracked fluorescently labeled montmorillonite particles in wheat and found they could bypass traditional root barriers, entering through lateral root junctions. The findings suggest a novel pathway for nutrient delivery, potentially revolutionizing sustainable fertilizer design.
A team of international researchers observes and controls how angular momentum is transferred and conserved within a crystal lattice using terahertz laser pulses. The experiment reveals a surprising effect: during the angular momentum transfer, the direction of rotation reverses due to the rotational symmetry of the material.
Researchers discovered that plants from arid regions have stronger suberin barriers in their roots, helping them cope with water stress. A new gene regulating suberin was identified, linked to the plant hormone abscisic acid, which plays a key role in responses to environmental stresses.
A scoping review reveals that participatory practices are crucial for successful multi-actor collaboration in landscape planning and governance. The study identifies a wide range of participatory tools, but highlights varying objectives, applications, and effectiveness across contexts and phases.
A multicenter cross-sectional study found hypertension significantly associated with extrahepatic cancers in the MASLD population. Metabolism-based treatments may have a protective role against extrahepatic cancers in individuals with FIB-4 scores ≥ 1.3.
A new study by MIT researchers finds that electric vehicles generate less greenhouse gas emissions and do not cost more than comparable gas-powered vehicles for most US drivers. The analysis considers individual driving patterns, meteorological data, and fuel prices to provide a comprehensive picture of emissions and costs.
Researchers at University of Witwatersrand and University of East Anglia have discovered a way to control light by exploiting its natural geometry. Light can develop chiral behavior, meaning it acts like left or right hand, while traveling freely through space, without mirrors or special materials.
A new grayscale lithography technique called PG-LDW is introduced, achieving sub-nanometer resolution in 3D structures. This process enables precise control over the depth profile of photoresists, opening opportunities for next-generation micro/nano-integrated devices.
Researchers found that individuals with a 'news will find me' mindset consider social media friends and algorithms as trustworthy as professional editors and journalists. This can lead to a reliance on unverified information and undermine traditional news sources.
Researchers found that winter seasonality and vegetation type significantly impact bacterial, fungal, and protistan communities in subtropical wetlands. Invasive plants disrupt native habitats, while restoration projects may boost microbial diversity but reduce protistan diversity.
A study of the 2005 Fukuchiyama-Line derailment accident reveals failures in organizational management as the root cause. The analysis found that skill development systems based on two-way communication among drivers are the most effective measure for preventing such accidents.
Researchers have identified RBPMS as a key player in driving Acute Myeloid Leukemia (AML) progression. The study proposes a novel therapy targeting the FOXO1 protein, which is enhanced by RBPMS, to selectively eliminate leukemia stem cells and improve treatment outcomes.
A study published in Cell Reports Medicine reveals that traumatic experiences during critical periods of life, particularly childhood to early adulthood, have lasting impacts on brain development and behavior. The research found that the timing of trauma, not its type, plays a key role in determining distinct behavioral outcomes.
A study found that PEG tube aspirate and vomitus display distinct color patterns, with the aspirate being yellow-green and the vomitus dark brown. This contrast can serve as a diagnostic clue for gastric outlet obstruction in resource-limited settings.
Machines with advanced AI capabilities are being developed to restore lost senses such as sight and sound, and even simulate touch and taste. This technology has the potential to revolutionize various fields like healthcare and education, but also raises serious concerns about privacy and manipulation.
Researchers at KIT have developed a method for gentle, three-dimensional rotation of microscopic objects using laser-driven flows. This innovation enables more effective capture of cellular structures and opens up possibilities for contact-free micromanipulation and precise manufacturing.
Researchers have developed a microfluidic spray drying technology to rapidly synthesize high-phase-purity HE-NVPF cathode materials, outperforming traditional batch methods. The new method enables scalable energy storage solutions with ultra-fast charging speeds and high energy density.
A survey study found that over 1 in 5 adult firearm owners living with children under 18 years store at least one loaded gun in an unlocked location, posing a significant risk to child safety. More effective strategies are needed to motivate parents to secure their firearms and prevent accidents.
A new study from the University of Surrey highlights the failure of major actors to work together as a major barrier to digital inclusion. Despite improvement in access to mobile networks and digital skills, whole communities remain excluded from education, finance, and basic services due to fragmentation of effort.
A new study reveals that a single gust of wind transported cesium-rich microparticles (CsMPs) across Fukushima Prefecture, contaminating the area with high levels of radioactivity. The particles' uneven distribution reflects weather conditions and pose an additional environmental and health risk.
The study identified amino acids crucial for ligand selectivity in two groups of receptors, β-adrenergic and D1-like dopamine receptors. By modifying these amino acids, the researchers made each receptor prefer its native ligand. The findings suggest that regions outside of the primary binding site also play a role in selectivity.
Researchers introduce a novel approach to enhance solar thermal energy storage efficiency by anchoring the phase-change front, preventing its accumulation at the source. The continuous-flow system delivers a charging power of 0.54 kW and a solar thermal storage efficiency of 49.7%, outperforming conventional diffusion-limited approaches.
The study found that stage IV breast cancer incidence increased across ages and sexes, while overall survival improved despite the increase. Researchers highlight the need for further investigation into factors contributing to the rise in incidence, including potential changes in breast cancer screening and other conditions.
Prescriptions for ivermectin and benzimidazole increased significantly following a high-profile podcast endorsement, with the highest rates among men, White patients, and those in the US South. The study raises concerns about celebrity endorsements influencing people to turn to unproven treatments.
A recent study reveals how orbital effects shape the high-field phase diagram of Ising superconductors, providing a theoretical basis for understanding vortex phase transitions at high magnetic fields. The research also demonstrates that finite-momentum pairing configurations can form under in-plane magnetic fields, leading to a new ty...
A study by researchers at the University of Pennsylvania School of Medicine has uncovered a fundamental rule governing gene arrangement inside the cell nucleus. By adjusting the balance between gene activity and DNA folding, they can partially restore expression of a key gene involved in Friedreich's ataxia, a neurodegenerative disorder.
Self-activating catalysts continuously improve during operation due to material reorganization and surface interactions with water and electrodes. The researchers outline future directions to accelerate sustainable hydrogen production, including standardized protocols and new approaches like seawater electrolysis.
A study published in JMIR Aging predicts early mobility decline in healthy adults aged 45 using a set of home-based measurements and AI. The researchers identified six essential factors, including age, muscle power, and diet, that accurately predict future mobility struggles.
A new study finds that individuals with higher resilience tend to place greater weight on positive aspects in cost-benefit decisions, a process mediated by brain activity. This regulated handling of negative information is linked to increased acceptance and improved psychological resilience.
A recent study found that ivermectin-benzimidazole prescribing increased rapidly following a celebrity endorsement in January 2025. This trend was particularly concerning among patients with cancer who may delay conventional treatments for unproven therapies, potentially worsening their disease progression.
Researchers have developed a new approach to reducing bird collisions with wind turbines by using warning signals found in nature, such as yellow, red, and black colors. The study found that these colors combined with rotating motion were more frightening to birds than existing patterns used on wind turbines.
A new study reveals how sulfur compounds are metabolized under oxygen-deficient conditions, with microorganisms like Flavobacteria playing a key role. Taurine, an organic sulfur compound found in red meat and energy drinks, is assimilated only in low-oxygen waters.
Researchers identify a 'vertical conveyor' mechanism that transports moisture from the mid-latitudes to the Asian Water Towers through a process of nocturnal decoupling. This process integrates up to 30% of westerlies-advected moisture into the local cycle without precipitation, sustaining near-surface moisture accumulation.
Researchers studied the impact of Capitola, California's annual firework show on local brown bat populations, finding that the noise and lights disrupted their feeding patterns. The study revealed a measurable effect on bats' ability to hunt and catch prey during the display.
The Journal of Participatory Medicine launches a new article type focusing on participatory education and methods, bridging methodological gaps in public health research. The journal seeks innovative approaches to engaging the public in research and practice.
Korea University College of Medicine has established a full-cycle physician-scientist training system from undergraduate studies to graduate school, fellowships, and professorships. The institution will further improve the path of physician-scientists with support from the Korea Health Industry Development Institute.
Insilico Medicine's Pharma.AI platform combines with Ribo's expertise in oligonucleotide therapeutics, aiming to boost efficiency and certainty of clinical research. The partnership enables end-to-end empowerment of RNA interference and oligonucleotide therapeutics development.
A recent study reveals widespread exposure to harm among US teens using AI chatbots, with entertainment being the most common motivation. The study found that nearly half of teens experienced at least one risk, including exposure to unsafe content and encouraging risky behavior.
NUTRITION 2026 will feature new, unpublished research findings relevant to consumer choices, clinical practice and public policy. The meeting is the premier place to dig deep into the discourse on what we eat and why it matters.
Researchers analyzed over 7,000 salmon stomachs to understand their diet in different regions of the Salish Sea. The study found that year-round, herring are the most important food for adult Chinook salmon, while seasonal changes affect the diversity of prey.
A new regulatory and financial architecture is needed to support novel carbon dioxide removal technologies, such as biochar and direct air capture. A tiered auction framework suggests governments setting targets and minimum quality standards, then running reverse auctions that specify target volumes and price ceilings.
Climate warming is projected to shift the production of key bioenergy crops to unsuitable locations, potentially leading to deforestation and releasing stored carbon. The study's findings highlight the need for a more nuanced assessment of bioenergy strategies in light of climate change.
A team of researchers has developed a deep learning-based method called DeepAFM to analyze noisy atomic force microscopy (AFM) images and infer protein states. The method produces accurate results, even with background noise and scanning distortions.
The SLEEP 2026 annual meeting will bring together leading sleep medicine professionals to discuss the latest research and advancements in sleep care. The event will feature over 1,400 research abstracts, keynote addresses, and a showcase of the latest products and technologies in sleep medicine.
A new study by researchers at Oregon State University suggests that restoring landscapes shaped by frequent low-intensity fire does not conflict with spotted owl conservation. The study identified areas suitable for spotted owl nesting and roosting that are more likely to persist through fire, providing insights for land managers to pl...
A study found that transposable elements, once considered non-functional DNA, contribute to the evolution and expansion of gene regulation during neural development. The findings suggest a two-phase model of TE acquisition during evolution, involving both ancient and more recent expansions that shaped modern gene regulatory networks.
Research found that girls born to mothers with higher insulin resistance during pregnancy are more likely to have more abdominal fat at age 7. Maternal insulin resistance was not associated with body fat in boys, suggesting girls may be more susceptible to the mother's insulin resistance during late pregnancy.
The FDA has approved an AI-based early warning system for sepsis, developed by Johns Hopkins University researchers, which detects the condition hours faster than doctors and has reduced deaths by nearly 20%. The system, known as Targeted Real-Time Early Warning System, integrates electronic health records with advanced clinical AI to ...
A new study has mapped the histamine system in the brain, revealing its role in regulating emotions, stress, and decision-making. The findings provide a framework for understanding how histamine contributes to brain function and could point towards new treatment strategies for histamine-related conditions.
Researchers discovered a small molecule that degrades SMARCA2/4 by engaging two distinct E3 ligase systems, creating a molecular backup for targeted protein degradation. This dual-engagement effectively increases the robustness of cancer therapies by making it harder for cells to escape treatment.
A team of scientists has found a naturally occurring Voronoi pattern in the Chinese money plant, which helps explain how plants create complex patterns on their leaves. This discovery sheds light on how plants solve problems in nature and may provide new insights into the math underlying evolution and development.
A comprehensive study analyzed human pancreatic islet cells from 299 nondiabetic donors, revealing the impact of endocrine cell composition on islet function and diabetes risk. The study found that the presence of delta cells, which secrete somatostatin, is associated with poorer insulin secretion.
A novel antibody, NG101, accelerates the regeneration of damaged spinal cord tissue by neutralizing a protein that blocks nerve fiber growth. This therapy enables new nerve fibers to form functional connections, allowing patients to become more independent and potentially recover arm and hand function.
A personalized vaccine has been shown to be safe and effective in treating glioblastoma, a fast-growing brain cancer. The vaccine elicited robust and broad immune responses that appeared to increase recurrence-free survival in patients after surgery.
Scientists have successfully measured incredibly small amounts of energy using a novel calorimeter technique, achieving a world-first in sensitivity. The breakthrough could pave the way for counting individual photons and detecting elusive dark-matter axions in space.
Researchers from MIT developed a technique to detect and precisely measure second-order harmonic corrections in superconducting quantum circuits. This analysis revealed the source of these distortions, which can cause quantum circuits to perform differently than expected.
Research at Nagoya University suggests that individuals with higher autistic traits use labeling as a way to cope with uncertainty, reducing emotional stress. The study found a link between autistic traits and lower anxiety levels when people are able to put their feelings into words.
Researchers at WashU Medicine conducted a clinical trial showing that genetically engineered donor stem cells can prevent toxic side effects and improve treatment options for patients with AML and MDS. The study found that removing the CD33 protein from donor stem cells helped target cancer cells while leaving healthy cells untouched.
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a complex hormonal disorder impacting 1 in 8 women globally, affecting weight, metabolism, mental health, skin, and the reproductive system. The name change aims to improve diagnosis and care for this previously misunderstood condition.
The collaboration aims to explore the role of transportable optical frequency standards in international time and frequency metrology. Transportable OFS are considered a promising approach to support comparisons of independent realizations of the second, with the goal of achieving consistent contributions to Coordinated Universal Time.
Researchers identified a defense mechanism in intestinal stem cells that actively responds to Salmonella infection, differentiating into antimicrobial Paneth cells to limit bacterial persistence. The study suggests that stem cell differentiation is part of an intrinsic protective program preserving intestinal function during infection.
A new report by University of Cambridge researchers highlights the human context of conservation efforts, finding that protecting 30% of the world's land and seas by 2030 will impact nearly half of the global population. The team suggests substantial investment and local involvement are crucial for successful implementation.
A comprehensive review of existing research shows no evidence that men's use of valproate increases the risk of neurodevelopmental disorders. The analysis combines data from large population-based studies in Denmark, Norway, Sweden, and Taiwan.
A study by Osaka Metropolitan University found that women with a higher proportion of LOX cells in their white blood cells had a lower likelihood of achieving natural pregnancy. The researchers suggest combining AMH analysis with LOX measurement may improve prediction of natural conception.
Researchers design polymer networks to replicate dynamic behaviors inspired by biological systems. Self-oscillating gels exhibit rhythmic motion similar to a beating heart, while artificial photosynthetic gels convert light into chemical energy.
Researchers at Chalmers University of Technology developed an AI method that adapts fast charging to the health of the battery, increasing its lifespan by almost 23%. The new strategy uses reinforcement learning and takes into account the battery's chemistry and state of health.
Researchers at the University of Waterloo have developed a water-based pesticide formulation that outperforms conventional methods in delivering agricultural pesticides. The new solution uses nanostructured cellulose nanocrystals to stabilize pesticide droplets without chemicals or solvents.
A Korean research team has successfully developed a technology that converts carbon dioxide (CO₂) into liquid hydrocarbons such as gasoline and naphtha. The direct CO2-to-gasoline and naphtha production achieves pilot-scale production of 50 kg per day, overcoming conventional intermediate steps.
Pelvic organ prolapse affects up to half of all women, causing incontinence and chronic pain. A new survey reveals one in three women suffer in silence due to common misconceptions about the condition.
A study by Associate Professor Bettina Gildenhard explores the tensions between personal initiatives, national language policies, and professionalism in volunteer-led Japanese language classes. The research highlights the need for a balanced approach, increasing investment in professional language educators while supporting volunteer i...
Researchers analyze helium isotope readings from geothermal springs in Zambia's Kafue Rift to confirm the presence of a weakness in the Earth's crust that has broken through to reach the mantle. The discovery could have significant economic implications for geothermal energy and potentially influence the future shape of Africa.