A study by Baylor College of Medicine researchers identifies a set of dysfunctional genes and specific cell types that are vulnerable early on to genetic changes in Rett syndrome. The research reveals that even healthy cells can be influenced by their environment, contributing to widespread brain dysfunction in the disease.
A study published in PLOS Global Public Health reveals a significant regulatory inconsistency in the management of products associated with fatal self-harm, including firearms, pesticides, and alcohol. The authors argue that a more consistent approach is needed to prevent suicide by treating known harmful products as the problem, rathe...
Research reveals that dead foundation species continue to influence ecosystems through their physical remains, promoting recovery in some cases and hindering it in others. This understanding can help manage and restore ecosystems, reducing the need for expensive interventions.
Research suggests fish and shellfish harvests played a key role in the economic system of the Canary Islands. Archaeologists found specialized fishing tools, thousands of fish scales, and evidence of early food preservation techniques.
A study of 2,044 older Japanese adults found that lower vitamin C levels were associated with lower gray matter volume and reduced connectivity within the default mode network. Optimal vitamin C levels may support cognitive function, but further research is needed to explore the biological mechanisms.
The University of Bath has recruited leading psychiatric geneticist Professor Laura Huckins to lead mental health research, focusing on eating disorders and PTSD. She aims to provide answers and treatments for vulnerable populations, combining genetic data and human brain studies to predict individual responses to their environment.
Monash University researchers found that exercise may boost muscle mass and strength in older adults by boosting a key protein called NOX4, which naturally declines with age. The study suggests restoring NOX4 levels could combat biological ageing and improve overall health.
New degradable sensors developed by Lancaster University researchers track biological activity in soil using a biodegradable substrate nibbled on by microbes. This technology offers insights into soil's response to climate events and storage of carbon, providing a better understanding of soil health and microbial processes.
Research by Lancaster University and the Indian Institute of Technology, Kanpur found that vulnerable families coped with food insecurity by limiting food diversity, taking loans, and temporarily withdrawing children from school. The study highlights the importance of local social networks and government support in mitigating crisis.
The Konstanz 'Village Lab' project will create an interdisciplinary programme on democracy in rural areas, providing students with hands-on experience. The four-year project aims to prepare students for active roles in shaping democratic processes and strengthening societal dialogue between the university and local regions.
Research published in Frontiers in Endocrinology reveals gestational diabetes influences fetal metabolic programming, shaping future risk of obesity and diabetes. Biomarkers such as leptin and adiponectin may identify children at increased risk, enabling personalized preventive strategies.
Psittacosis is experiencing a notable resurgence in China, driven by increased diagnostic awareness and metagenomic next-generation sequencing. The disease has significant gaps in current knowledge, including inadequate characterization of molecular epidemiology and lack of unified national surveillance framework.
A new study led by Penn State researchers found that just four minutes of daily strengthening exercise can significantly improve key factors in quality of life for aging adults. The study showed that strength and mobility improved dramatically in adults aged 65 and older, leading to better independence and reduced fall risk.
A new Brookings Institution study found that ICE surges have caused significant job losses in cities where enforcement is most active. Between 51,000 and 297,000 American-born workers lost their jobs due to the surges, which also led to widespread disruptions throughout industries such as construction.
Four SfN members, Christine Holt, Kelsey C. Martin, Erin Schuman, and Oswald Steward, have been awarded the 2026 Kavli Prize in Neuroscience for their discoveries on local protein translation in neurons.
Researchers found that ground subsidence has undergone phases of variable change, creating significant implications for coastal communities. The rate of vertical land motion is nonlinear in many coastal areas, particularly in Louisiana and the Mississippi Delta.
A team of University of Amsterdam researchers show that activity can fundamentally alter the transition from disorder to order in soft matter physics. For living cells, bacterial chains and clusters of worms, this process is more complex, with activity preventing the formation of a fully ordered state.
A clinical trial found that abatacept significantly reduces the progression to rheumatoid arthritis in patients with palindromic rheumatism. Patients treated with abatacept experienced improved symptoms and reduced risk of developing arthritis, compared to those receiving hydroxychloroquine treatment.
Researchers have discovered a 'galaxy-killing wind' that could explain the origin of massive dead galaxies in the early universe. Using JWST and ALMA, they imaged a galaxy one billion years after the Big Bang, revealing a huge plume of cold gas extending far away from it.
A new study from the University of Copenhagen found that combining fractions with a basketball improves pupils' mathematical skills in primary school. Pupils who participated in an eight-week teaching programme performed 15% better in fractions tests compared to a control group.
Childhood maltreatment alters fear-related brain function and systemic inflammation, modulating their connection. The timing and type of abuse or neglect shape this link, with early trauma affecting threat-regional brain areas and late trauma impacting regulatory brain regions.
A comprehensive study reveals the Bornean ferret badger is found only in Sabah's western highlands, with a previously unknown population discovered in Nuluhon-Trusmadi Forest Reserve. The species' range and distribution are largely confined to mountain landscapes, highlighting the need for conservation efforts to protect its habitat.
A new study found that individuals with a 'Sleep Appreciate' profile are willing to pay more for better sleep, while those with a 'Sleep Devalue' profile require less money. The research suggests integrating economic perspectives into sleep health research may offer novel insights for designing interventions.
A study by DZNE shows that smartphone-based memory tests can detect subtle cognitive decline in people with mild cognitive impairment (MCI) more quickly than conventional testing. This approach has the potential to accelerate clinical trials for new dementia drugs and be used in routine care.
Researchers are investigating the role of MYRF in HLHS, a severe congenital heart defect requiring multiple surgeries. The study aims to better understand how MYRF regulates heart development, with potential implications for improved care and long-term outcomes.
Dr. Donald Lloyd-Jones, a renowned cardiologist and director of the Framingham Heart Study, has been honored with the American Heart Association's Gold Heart Award for his groundbreaking work in promoting cardiovascular health and preventing cardiovascular diseases. His research focuses on the mechanisms and life course of cardiovascul...
The study demonstrates a direct hydrazine substitution strategy to construct fused heterocyclic energetic skeletons with tunable structural and energetic properties. The compounds exhibit exceptional thermal stability and low impact sensitivities, making them suitable for heat-resistant applications.
Researchers detected pathogenic species of Sporothrix in the internal organs of mammals, birds, and reptiles that were killed by vehicles on Brazilian roads. The study reveals a new reservoir for fungi, highlighting the need for surveillance.
The review highlights advances in multi-scale bioelectrical interactions, analyzing challenges such as interface impedance and material-tissue compatibility. It emphasizes a shift towards application-driven design, integrating biological needs with material selection and device engineering.
A new study from Penn State College of Medicine found that excessive daytime sleepiness is associated with a higher risk of both prevalent and incident hypertension. Individuals reporting excessive daytime sleepiness had 52% higher odds of prevalent hypertension and 74% higher odds of incident hypertension compared to normal controls.
As precision agriculture technologies spread, on-farm experimentation has become increasingly common, generating vast amounts of data that require advanced analytical approaches. Researchers are now using statistical methods like linear mixed models and Bayesian approaches to handle the complexity of real-world data, enabling farmers t...
Old Dominion University has launched a National Security Institute to accelerate research and technology solutions for pressing national security challenges. The institute will bring together researchers' strengths in AI, autonomy, and coastal systems to deliver innovative solutions.
A new drug targeting RAS, a pathologically altered protein causing 40% of colorectal and 90% of pancreatic cancers, has been developed. The molecular eraser, RIBOTAC, stops the production of RAS by degrading its mRNA, but surprisingly triggers changes in cancer cells despite minimal impact on protein quantity.
Researchers have found that wheat plants can produce natural compounds that suppress nitrifying microbes in the soil, reducing nitrogen losses. The study screened 18 benzoxazinoids and found seven capable of strongly suppressing nitrification, with benefits for fertilizer efficiency and climate change mitigation.
A recent study published by the University of the Basque Country found that girls are the biggest consumers of psychotropic drugs among adolescents in most European countries. The research team analyzed data from 32 European countries and discovered a significant link between consumption rates, gender equality, and economic level.
Researchers at Baycrest have made significant contributions to the understanding of paratonia, a common yet underrecognized condition in advanced dementia. The studies explore clinical features, recognition, and assessment approaches, emphasizing the need for more compassionate and person-centered care.
A new study found that surgical menopause causes more severe genitourinary syndrome of menopause phenotype, with increased symptoms and exam findings compared to natural menopause. This may lead to a higher risk of vaginal dryness, pain during intercourse, urination, reduced sexual desire, and postcoital bleeding.
James Dante, a leading expert in corrosion science, has been named Fellow of the Association for Materials Protection and Performance. He is renowned for developing laboratory test methods to predict corrosion and coating system degradation, and his work has been instrumental in standards development.
A new study reveals substantial differences in gene expression patterns between aging mouse and human skeletal muscle. Fewer than 5% of biological pathways show shared changes, emphasizing the need for cross-species targets in aging research.
Researchers used an AI model to detect Bryde's whale calls in seismic data collected in the South China Sea. The model achieved high accuracy, detecting calls over 96% of the time and identifying seasonal variations in whale behavior.
A new study by Chalmers University of Technology found that biocide-free silicone paint is the most effective against fouling, while an 'eco-friendly' paint was revealed to be extremely toxic. The results suggest copper-free coatings can be just as effective as those containing more copper.
A study published in Neuroepidemiology found that individuals with traumatic brain injury (TBI) are at a higher risk of dying from brain cancer compared to the general population. The research, which analyzed data from over 20,000 TBI patients, revealed that those with severe TBI were nearly 14 times more likely to die from brain cancer.
A study using Galen's ancient texts highlights the inability of digital simulations and virtual reality to transmit the physical intuition needed for clinical practice. Researchers recreated a dissection to demonstrate that written instructions and digital tools cannot replace hands-on experience.
Scientists have mapped the tiny antenna-like structures in giant kelp that allow it to efficiently capture light and remove carbon dioxide from the atmosphere. This discovery may lead to new ways to boost crop growth and capture carbon dioxide, providing sustainable food sources in a warming world.
A new study found that pregnant women's expectations about postpartum sleep predicted their actual sleep quality after delivery, with 70% of women anticipating poor sleep. The study suggests that addressing sleep-related beliefs during pregnancy and treating postpartum anxiety may improve sleep and emotional well-being in new mothers.
A new study maps future risk of dengue transmission in Costa Rica by analyzing climate factors and epidemiological records. The research reveals a complex interplay between seasonal weather patterns and disease transmission, highlighting the need for locally informed, seasonally adaptive strategies.
Researchers found that friendly, choice-oriented language in AI chatbots boosts patient engagement, while aggressive phrasing and blurred human-AI boundaries put them off. Patients appreciate personalized interactions, but are wary of data security concerns.
Researchers at UCF-led excavation in Kurdistan region of Iraq discover substantial group of cuneiform administrative tablets and evidence of large-scale destruction, mass graves, and citywide fortifications. The findings provide a clear archaeological record of siege warfare and urban life during the Middle Bronze Age.
Delirium is a common and preventable complication in older surgical patients, with verified geriatric surgery programs screening nearly every patient. Non-accredited hospitals screen only half of their patients for delirium, leading to a stark gap in care.
Steward's groundbreaking research revealed protein-producing machinery located near synapses, demonstrating that neurons can manufacture proteins locally. His work has boosted comprehension of neurodevelopmental disabilities and opened new pathways for developing therapies to preserve cognitive function and restore neural connectivity.
Researchers at KAIST developed Video-Based Optimal Transport (VOTP), a technology that enables robots to understand human intentions and choose actions on their own with minimal data. This breakthrough accelerates the development of physical AI, which is expected to drastically shorten development time and costs.
A new review highlights advances in preventing bone loss in people with rheumatoid arthritis, showing that modern antirheumatic therapies can significantly reduce both localized erosions and generalized bone loss. Emerging imaging technologies like HR-pQCT have been found to detect subtle bone erosions earlier and more sensitively.
Researchers at the International Institute for Applied Systems Analysis have built a dataset of global migration flows from 1990 to 2023, revealing a true per-capita increase in human mobility. The dataset shows that migration has become more common overall since 2000, with dips only during the financial crisis and Covid-19 pandemic.
A pediatric ophthalmologist is leading a $1 million NIH grant to study the genetics of cataracts in children. The goal is to develop a comprehensive AI-assisted database of genes associated with potential diseases.
Researchers found that daunorubicin effectively inhibits bacteriophage infection in bacteria, triggering mutual destruction and killing the bacterial cell. The discovery opens up new avenues for phage therapy development, especially against antibiotic-resistant infections.
Valsamo Anagnostou, Jordan Berlin, and Olisaemeka Ogbue receive ECOG-ACRIN's Young Investigator Award, Remarkable Mentor in Oncology Award, and Paul Carbone, MD Fellowship Award for outstanding contributions to translational research, mentorship, and improving cancer care. The awards are funded by the ECOG Research & Education Foundation.
The new project aims to build self-regulating AI agents that can recognize uncertainty, explain their decisions using past experience, and improve their understanding of the world through corrective feedback. The goal is to make future physical AI systems more trustworthy and useful in real-world settings.
A new study by Concordia researchers suggests that carefully habituating wild gorillas to non-threatening humans can help them overcome long-term aversions to people. Over an eight-year study in Cameroon, the animals' responses to human presence slowly changed from aggression and avoidance to curiosity and indifference.
Researchers have developed an algorithmic tool called CytoSignal that can analyze spatial transcriptomic data to infer cell-cell communication. The method can identify defective signaling interactions underlying diseases and potentially lead to new treatments by targeting specific receptor proteins.
Researchers developed breakthrough methods to track individual bird species during migration by combining participatory science data with weather radar technology. The BirdFlow project provides species-specific migration estimates across North America, addressing a long-standing limitation in migration monitoring.