Researchers developed a new method to create smart multifunctional materials by combining vanadium oxide and gold nanoparticles in a single process. The resulting films show temperature-dependent optical changes and exhibit enhanced antibacterial activity under light irradiation.
Scientists have developed a nanopore sensor that can detect and distinguish between microcystin congeners, a family of cyanotoxins threatening drinking-water supplies. The technology detected two closely related microcystins in Lake Geneva water with nanomolar sensitivity.
Researchers developed two technologies to improve electrical conductivity in organic materials, generating more charge carriers and reconnecting broken pathways. The findings showed significant improvements in conductivity, with one technology increasing electron concentration by over 3,000 S cm−1.
A global meta-analysis of over 4,200 studies found that microplastics can alter cadmium uptake and movement in plants, reducing oxidative stress and nutrient imbalance. However, the effects vary greatly depending on particle size, polymer type, concentration, and environmental conditions.
A study of 3786 children found no significant associations between screen use and developmental difficulties, except for very high use of electronic games. Early high screen use was associated with greater difficulties at 10 years old, but not sustained at 15 years.
The Gerontological Society of America appreciates Senate appropriators' efforts to ensure federal grant funding is administered consistently with congressional intent. This decision delays implementation of a proposed rule that would place political appointees in charge of approving federal grants, affecting 42 federal agencies.
A new study by Flinders University suggests that excessive use of dating apps and pornography can lead to a weaker sense of existential meaning in romantic love. Experts found that people who used these platforms mindfully were less likely to become hooked and reported fewer problems with their views on love.
The University of Tennessee is expanding its research excellence with the addition of eight exceptional researchers, tackling pressing challenges in fields like precision health, advanced computing, and sustainable materials. The new faculty members bring expertise that builds on the university's strengths and solidifies its standing a...
Lehigh University researchers develop comprehensive mathematical model of the neural circuitry linking the gut and brain to regulate stomach function, opening new pathways for treating chronic digestive disorders through targeted vagus nerve stimulation. The digital twin could help accelerate therapy development and improve quality of ...
Researchers develop ferroelectric reconfigurable homojunctions for energy-efficient in-Sensor computing, achieving sub-fJ programming energy and exceptional image processing performance. The device integrates sensing and processing units, enabling simultaneous optimization of functional reconfigurability and energy efficiency.
A recent study found that both full and limited endoscopic sinus surgery significantly reduce symptoms in patients with chronic rhinosinusitis, improving quality of life. Full surgery showed better results in recovering sense of smell and reducing nasal polyp size.
Researchers propose using Caenorhabditis elegans to identify novel ferroptosis regulators through chemical mutagenesis screens and genetic modifier screens. This approach could help address unanswered questions in ferroptosis biology, including sensitivity variations between cells and tissues.
A single-center randomized controlled trial found that a novel probiotic-enriched tube feeding formula reduced serious gut complications dramatically compared to standard enteral nutrition. The probiotic group showed no cases of diarrhea, while the control group experienced a 60% rate of diarrhea.
A research team led by Professor Hyoyoung Lee has developed a new catalyst that converts carbon dioxide into ethanol with high selectivity. The catalyst achieves 69% ethanol Faradaic efficiency in MEA systems, demonstrating promising operational stability and product selectivity.
Lindsay A. Farrer, PhD, is a leading researcher in Alzheimer's disease and genetics, leveraging large datasets to identify genetic variants and biomarkers. His work aims to develop novel therapeutic targets for personalized medicine.
Researchers at Kyushu University found that microwave heating creates high-temperature regions on nickel nanoparticles, accelerating hydrogen production and paving the way for low-carbon chemical manufacturing. The study showed a six-fold increase in hydrogen production compared to conventional heating.
A study by Newcastle University found that local knowledge, improved evacuation preparedness, and resilient communication channels can reduce loss of life during glacial lake outburst floods. The research highlights the importance of strengthening existing early warning systems to better reflect community experiences.
This randomized clinical trial evaluates safety and efficacy of intra-arterial thrombectomy vs. medical management in patients with large-core infarcts after an acute ischemic stroke. The study found that endovascular treatment showed significant benefits in improving outcomes.
A recent McGill University study found that participants in an upright posture performed better at a risk-taking task and reported more positive feelings. The researchers suggest that everyday features of our environment, such as workplace ergonomics, can subtly influence mood and behavior.
Researchers at UCLA created a 'cell village' approach to study the genetics of brain cell fitness, which revealed that individuals with autism are more likely to have faster-dividing cells. This discovery could lead to early mechanistic understanding of how autism develops and improve personalized treatment.
Researchers found that male sperm whales emit slow, low-frequency clicks with extremely high source levels, which can be heard up to 70 kilometers away. These clicks are not used for echolocation but may serve as a form of communication or advertisement, potentially linking to honest signals of size.
A study examines genetic variants on the X chromosome for association with ESRD risk, identifying several loci significantly linked to ESRD. The findings collectively explain a portion of ESRD heritability and provide insights into potential disease mechanisms.
Researchers used connected speech analysis to distinguish between nonfluent, logopenic and semantic PPA variants with high accuracy. The study also showed expected atrophy associations and discriminated common neuropathologic classes in an autopsy-confirmed subset.
Researchers tested cortisone eye drops to slow ROP progression in 100 premature babies. The intervention reduced treatment-requiring ROP by 47% compared to placebo.
Researchers have identified a blood marker that can track the hidden progression of multiple sclerosis (MS), even in the absence of relapses. Elevated levels of glial fibrillary acidic protein (GFAP) are associated with disability progression, while changes in GFAP during treatment predict later risk of progression.
A study by Osaka Metropolitan University found that neighborhoods with stronger senses of safety tend to have longer sleep durations, while highly walkable streetscapes are associated with shortened sleep duration. Greenery and high enclosure are also linked to longer sleep and reduced insomnia symptoms.
Researchers at Penn State and the USDA have identified 10 genomic variants associated with increased virulence in Marek's disease virus, a deadly illness affecting chickens. The study could inform the design of more effective vaccines that can prevent future breakthroughs.
Researchers review recent progress in supramolecular polymer science, highlighting key advancements in material morphology, physical mechanisms, and engineering applications. The field holds promise for developing recyclable materials, devices, and intelligent systems with adaptable properties.
Adolescents with idiopathic scoliosis show significant differences in muscle synergy organization compared to healthy controls, indicating a reorganized trunk motor control. This reorganization is highly individual and may serve as an objective tool for tailoring rehabilitation to each patient's specific coordination profile.
Researchers develop a comprehensive roadmap for halide-based solid electrolytes, enabling high-performance and scalable energy storage systems. HSEs exhibit exceptional electrochemical stability, wide stability windows, and enhanced air stability, promising applications in Li-ion, Na-ion, and post-lithium chemistries.
A recent Finnish study found that exposure to dog-associated microbes in early childhood reduces the risk of respiratory tract infections and antibiotic courses. Dog ownership is linked to higher richness and diversity of microbiota, but not directly associated with reduced infection rates.
Researchers found that high-intensity sports involving explosive movements stimulated bone formation most effectively. Recreational football and handball were associated with increases in substances linked to bone formation, while walking and traditional gym-based exercises were less effective. This suggests that low-intensity exercise...
Researchers found that microbial carbon fixation persists beneath the ice of Qinghai Lake, the largest saline lake in China, despite low temperatures and limited light. Dark-dependent carbon fixation was significantly greater than light-dependent fixation, suggesting a major winter carbon assimilation pathway in this saline lake.
Cohort studies reveal associations between glycan patterns and disease states in cancer, cardiovascular disease, and autoimmune disorders. Glycan biomarkers may enable earlier detection and treatment selection.
A new online test, MEDWACS, can detect people with prediabetes or undiagnosed type 2 diabetes with high accuracy. The test measures seven parameters, including thigh length, which is linked to a person's risk of developing the condition.
Researchers use DNA sequencing to monitor microbial changes and detect infections more rapidly than traditional methods. This technology has the potential to improve diagnosis, treatment, and patient outcomes for people with cystic fibrosis and other infectious diseases.
Scientists create a hybrid system that combines the strengths of two materials to generate broad ranges of light frequencies on a chip. The device uses silicon nitride and silica, allowing for Raman lasing and optical frequency combs with high efficiency and power conversion.
A new study identifies butterfly species most sensitive to environmental change, offering a practical framework for monitoring biodiversity and assessing forest restoration. The research highlights the conservation importance of specialist butterflies and their declining populations due to habitat loss.
A cohort study of 2771 male children found no evidence that neonatal medical male circumcision is associated with an increased risk of autism spectrum disorder. The study also examined the effects of acetaminophen use during and after the procedure, but found it to be uncommon.
A phase 3 clinical trial found that adding high-dose vitamin D to standard treatment did not improve progression-free survival in patients with metastatic colorectal cancer. Median progression-free survival was 11.8 months with high-dose vitamin D compared to 10.3 months with standard dose.
High-capacity lithium-ion batteries face challenges during operation, particularly activation, where capacity drops initially and recovers gradually. Researchers found that particle size plays a decisive role in determining whether activation occurs, with larger particles exhibiting pronounced behavior.
ISM8969/HT-001 is an orally available, brain-penetrant NLRP3 inhibitor with promising in vitro and in vivo profiles. The clinical trial aims to evaluate its safety, tolerability, and efficacy in patients with Parkinson's disease.
A new combination therapy selectively targets cancer cells and senescent cells by exploiting metabolic vulnerabilities, improving physical performance and extending lifespan. The treatment eliminates senescent cells, reduces cancer cell viability and improves metabolic profiles in aged mice.
Researchers used synchrotron X-ray absorption spectroscopy and atomic-scale computer simulation to measure how iron and cobalt atoms individually respond to temperature change. Iron and cobalt both contribute to suppressing thermal expansion, but iron's effect is stronger and shifts with small changes in the iron-to-cobalt ratio.
Research highlights the impact of skewed XCI on disease severity and identifies potential therapeutic approaches, including reactivating genes on the inactive X chromosome. Emerging techniques to measure XCI patterns hold promise for personalized therapies.
A Portland State University professor has received a nearly $1.2 million NSF CAREER Award to study the predator-prey relationship of Prochlorococcus, the ocean's most abundant photosynthetic life form. The project aims to understand how single-celled ocean predators hunt Prochlorococcus and its implications for the ocean's food web.
Researchers developed a skin-worn Janus bioelectrode that uses gradient impedance to suppress electromagnetic interference and maintain signal quality. The electrode achieved high recognition accuracy for human motion states when combined with electromyography and electrocardiography signals.
A molecular switch in tomato helps redirect energy towards roots under drought conditions, increasing water uptake capacity and drought tolerance. Overexpression of the SlTPP1 gene boosts dry matter allocation to roots, while silencing SlERF4 enhances this effect.
The first national-level assessment of coastal wetland submergence reveals that 84% are gradually inundating due to climate change-driven sea level rise. However, some wetlands may be able to migrate inland or build up sediment fast enough to keep pace with sea level rise.
Qassim University researchers can now publish their work openly in hundreds of top journals, increasing international collaboration and knowledge exchange. The partnership supports the university's values of transparency, innovation, and collaboration, and aims to amplify its growing research influence.
Researchers from Arizona State University challenge a decades-old theory by showing that genetics alone does not explain the origins of eusociality in insects. The study found that haplodiploidy, a genetic system, does not predict the evolution of eusociality across insects more broadly.
A study found that most cats adapt to indoor living with minimal issues, while owners experience improved peace of mind, closer bonds, and reduced veterinary costs. Practical strategies like environmental enrichment can support successful transitions.
A new prediction model developed by McGill University researchers can identify younger women at higher heart disease risk years before traditional screenings. The model takes into account pregnancy complications such as hypertension and gestational diabetes to estimate future risk.
The $24.9M grant will establish a national user facility for alloy-discovery campaigns using robotic systems and AI, freeing scientists to focus on discovery itself. ARM-MIP will democratize access to state-of-the-art research facilities and accelerate alloy development.
A randomized clinical trial found that dexamethasone eye drops reduced the progression of retinopathy of prematurity to severe disease requiring invasive treatment in preterm infants. However, no differences in adverse events were observed.
Research identifies novel FAK splicing variants in small cell lung cancer that promote proliferation, migration, and invasion. These variants confer resistance to chemotherapy and radiation, highlighting a new therapeutic vulnerability. Targeted therapy with FAK inhibitors shows promise.
Researchers have identified a promising strategy to improve the effectiveness of targeted therapies in advanced prostate cancer. By combining ADCs with a drug that blocks BCL-XL, they triggered greater cancer cell death and slowed tumor growth. The approach could offer a new strategy for improving antibody-drug conjugates against metas...
Researchers found that tumor cells use DDB1 to ubiquitinate PD-L1, allowing it to enter the nucleus and drive immune suppression. A new compound, thalidomide, disrupts this process, restoring sensitivity to immunotherapy in preclinical breast cancer models.
A randomized clinical trial found video laryngoscopy with a Macintosh blade (VLM) and hyperangulated blade (VLH) to have significantly higher first-pass success rates compared to direct laryngoscopy (DL). The study supports the use of video laryngoscopy as a new standard for routine airway management in adult patients.
A study published in Horticulture Research found that red-stemmed plants of Astragalus membranaceus var. mongholicus accumulate higher levels of isoflavones and volatile organic compounds associated with medicinal quality, while their stems are enriched with cyanidin-based anthocyanins that explain the red coloration.