Dr. Emily Flanagan's five-year NIH grant will investigate how energy intake and expenditure influence infant growth and future obesity risk. The study aims to improve energy-intake standards for infants and identify critical periods for interventions promoting healthy growth.
Researchers found that impaired peroxisomal function can increase insulin secretion while promoting insulin oxidation and disrupting pancreatic beta cell maturity. Healthy peroxisomes play a role in protecting insulin from oxidative modification and degradation, and helping beta cells maintain their specialized characteristics.
A study of 1.26 million bariatric surgery patients found 5.3% had extreme obesity, defined as a BMI of 60 kg/m² or higher. Despite a higher burden of health conditions, surgical risk remained relatively low, with complications occurring in 2.57% of cases.
The 2026 Childhood Obesity Conference, 'Be the Reason Kids Greaux Healthy,' will explore strategies for preventing and treating childhood obesity, bringing together healthcare professionals, researchers, educators, and community leaders. The conference will feature keynotes, sessions, and poster presentations on emerging topics in pedi...
Researchers highlight unanticipated benefits of GLP-1 medications, including reduced inflammation and lower risk of certain cardiovascular and musculoskeletal conditions. However, questions remain about lean body mass and nutritional health following weight loss associated with these medications.
Researchers are developing a smartphone-based platform that combines driving data, personalized coaching and parent engagement strategies to improve driving safety for teens with ADHD. The platform will use telematics to monitor driving behaviors while allowing parents and teens to set shared goals and track progress.
Researchers from Pennington Biomedical Research Center propose a new framework for defining and diagnosing obesity, which considers the effects of excess adiposity on organs and tissues. This approach provides a more biologically grounded and clinically actionable method for guiding treatment decisions.
A Phase 2 clinical trial shows that a THC/CBD combination significantly reduces agitation in hospice-eligible people with dementia. The study, conducted across multiple US sites, achieved its primary and key secondary endpoints, demonstrating the efficacy of this treatment approach for end-of-life agitation.
Researchers identified endotrophin as a biological marker that rises and falls with changes in body fat, reflecting changes in metabolic health. The study suggests endotrophin could serve as a valuable biomarker and therapeutic target for reducing obesity-related health risks.
Researchers from Pennington Biomedical will present findings on organoid models, GLP-1 therapies, and early-life nutrition. The center's broad research portfolio is represented at the annual meeting of the American Society for Nutrition.
The Pennington-Louisiana Nutrition Obesity Research Center has received a five-year, $5.66 million renewal grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The award reaffirms Pennington Biomedical's position as a national leader in nutrition, obesity, and metabolic health research. The center su...
Dr. Kaja Falkenhain receives the Peter J. Reeds Early Career Investigator Award for her groundbreaking work on human nutrition and metabolism. Her research focuses on cardiometabolic health and glycemic control, highlighting the impact of nutritional exposures on energy expenditure.
A new study from Pennington Biomedical Research Center in Louisiana demonstrates safe and effective bariatric surgery outcomes for young patients with severe obesity. The study found significant improvements in weight loss and obesity-related health conditions, highlighting the importance of multidisciplinary care models.
Dr. Tim Allerton's research focuses on heart failure with preserved ejection fraction (HFpEF), a condition affecting millions of Americans. His team aims to determine how declining hydrogen sulfide levels contribute to muscle function and exercise capacity in patients with HFpEF.
Researchers have identified high rates of overweight/obesity (82%) and hypertension (higher than statewide average) in Franklin Parish, with income levels linked to lower hypertension rates. Older residents are also more likely to have undiagnosed high cholesterol and diabetes.
Dr. Logan Townsend joins Pennington Biomedical to study the connection between metabolic disease and mental health, investigating circulating factors influencing anxiety and depression. His research program aims to improve both metabolic and mental health outcomes.
A longitudinal study found modifiable factors like emotion regulation, social support, and sleep quality influence psychological resilience in female athletes. Greater resilience was linked to lower rates of depression, anxiety, PTSD, and perceived stress.
The NOVO EXPENDITURE trial investigates the effects of a hormone-based treatment on weight loss compared to a reduced-calorie diet. Participants will undergo extensive physiological testing, including metabolic chamber sessions and regular weigh-ins, to assess the treatment's impact on energy use and body weight.
Dr. Corby Martin has been awarded the LPFA Endowed Chair in Nutrition at Pennington Biomedical Research Center for his groundbreaking research on nutrition and health behaviors. The chair recognizes his extensive experience leading interventions to modify health behaviors and outcomes, including food intake, exercise, and body weight.
A new study by Pennington Biomedical and collaborators found that Americans with the highest levels of obesity are undergoing fewer surgical procedures overall. Despite the increasing prevalence of extreme obesity, these individuals appear to be receiving proportionally fewer surgical interventions each year. The research highlights gr...
Dr. Mey directs the Mitochondrial Energetics and Nutrient Utilization (MENU) Laboratory at Pennington Biomedical, researching precision nutrition and metabolic health. He will represent Pennington Biomedical and the Academy as a Media Spokesperson.
Researchers from Pennington Biomedical will showcase their latest findings on prevention, care, and cures for diabetes and obesity at the American Diabetes Association's 2026 Scientific Sessions. The sessions will highlight cutting-edge advancements driving progress in diabetes research and management.
Researchers at Pennington Biomedical published the first study to estimate pediatric obesity prevalence among US children and adolescents aged 5-18 years using the new Lancet Commission definitions. The study found that many children are already experiencing measurable health impairments associated with obesity.
Dr. Owen Carmichael received the James W. and Neil Ann Parks Professorship for Dementia Research, Prevention and Treatment at Pennington Biomedical. His work focuses on developing advanced biomedical imaging techniques to better understand Alzheimer's disease and brain aging.
A new study published in the Journal of Science and Medicine in Sport found that most children meet guidelines for restrained sitting, but urban children and those with more vehicle time are less likely to meet the guideline. Higher levels of physical activity were associated with greater likelihood of meeting the recommended guideline.
Dr. John Apolzan and Dr. Leanne Redman, both from Pennington Biomedical Research Center, have been recognized as 2026 Excellence in Nutrition Fellows for their outstanding scientific contributions and leadership in the field of nutrition. They will be part of 69 new Fellows to be honored at ASN's annual meeting.
A research study, COACH trial, is testing different ways to help children and families improve their health through lifestyle changes delivered by primary care clinics. The study aims to assess the effectiveness of personalized nutrition counseling, community resources, and online interactive lessons on weight management.
Research by Dr. Hanim Diktas at Pennington Biomedical Research Center shows that combining GLP-1 receptor agonists with behavioral intervention leads to a greater reduction in 'food noise', a persistent thought about food disrupting daily life and healthy behaviors. The study found significant decreases in food noise for participants u...
A global study published in Nature Human Behaviour analyzed data from over 8,000 participants to investigate the connection between physical activity and emotional well-being. The results showed that mood improves with everyday movement, and people are more physically active when they feel better.
Regular physical activity is essential for mitigating the regain of lost weight after discontinuing GLP-1 medications. Exercise has complementary effects beyond energy balance, including improved insulin sensitivity and increased fat oxidation. Clinicians must develop individualized strategies to improve exercise adherence.
A two-day symposium brought together leading researchers, clinicians, and policy experts to examine the science surrounding ultra-processed foods and their impact on human health. Key findings include the biological mechanisms linking ultra-processing to chronic disease and opportunities for policy action.
Dr. Hannah Cabré has been appointed as an Assistant Professor and Director of the Aging, Gynecology, and Endocrinology Laboratory at Pennington Biomedical Research Center. Her research focuses on the role of female sex hormones in shaping nutrition, health, and performance across the lifespan.
A recent study published in Cell Reports identified a key pathway through which the hormone FGF21 influences eating behavior and energy balance. The findings highlight the importance of nutrition in brain function and suggest that FGF21-based therapies could be optimized to target specific brain circuits.
Dr. Gang Hu's research focuses on the complex interplay between lifestyle factors, biomarkers and genetic influences in chronic disease development. He has made significant contributions to understanding gestational diabetes mellitus and its long-term health effects.
The Pennington Generation study aims to explore the impact of physical activity, nutrition, and sleep on children's health and growth. The study will examine how these behaviors relate to weight gain and obesity over time.
Researchers found that exercise and aggressive cardiovascular risk reduction improved heart health, but did not produce measurable cognitive benefits over two years in older adults at risk for Alzheimer's disease. The study highlights a critical gap between vascular risk reduction and brain health.
A recent study published by Pennington Biomedical Research Center has shed light on the key drivers of chronic disease in Assumption Parish. The research found that residents with lower education levels are more likely to suffer from high blood pressure, high cholesterol, and obesity. This correlation suggests a strong link between edu...
The Greaux Healthy initiative, launched by Pennington Biomedical Research Center, aims to prevent and treat childhood obesity in Louisiana. Studies show that childhood obesity is a national healthcare crisis in Louisiana, with over 1 in 3 children living with overweight or obesity.
A combination of GLP-1 receptor agonist semaglutide and bimagrumab results in greater weight reduction while preserving lean mass in adults with obesity. The therapy combination addressed lean mass loss associated with GLP-1-based therapies, showing substantial weight loss over 72 weeks.
A Pennington Biomedical researcher published an editorial on the benefits of fruit intake for vascular health, citing a study on increasing fruit intake with avocados and mangos. The findings suggest that diets rich in fruits can improve nutrient status and health outcomes, aligning with the goals of the Food Is Medicine initiative.
Dr. Catherine Prater's research project aims to improve prediction models and uncover metabolic markers that explain individual differences in weight gain. She will use machine learning techniques to train and test prediction models using existing clinical trial data.
Dr. Candida Rebello's five-year NIH grant will explore lifestyle strategies to reduce excess body fat and declining muscle mass in older adults with obesity. The study aims to protect skeletal muscle health, independence, and quality of life for this rapidly growing population.
The DASH Diet, developed at Pennington Biomedical Research Center, has been ranked as the best heart-healthy diet and second-best overall by US News & World Report. The diet's focus on fiber, heart-healthy minerals, and whole grains helps lower blood pressure and reduce cardiovascular risk.
Pennington Biomedical researchers investigated competing body weight regulation models, analyzing the interaction of energy intake and expenditure. The study highlights the need to test state-of-the-art technology and could help explain why losing weight is challenging for some individuals.
Dr. Gang Hu, a leading expert in chronic disease epidemiology, has been appointed to the NIH Reproductive, Perinatal and Pediatric Health Review Group. He will evaluate studies on reproductive, perinatal, and pediatric health, with a focus on lifestyle factors and their impact on chronic diseases.
Dr. Jennifer Rood, Associate Executive Director for Cores and Resources, takes on interim leadership role at Pennington Biomedical Research Center while an international search for the next full-time Executive Director is underway. She brings over 30 years of experience in obesity and chronic disease research.
Pennington Biomedical Research Center launched its first international scientific symposium in Riyadh, Saudi Arabia, exceeding expectations with distinguished audience engagement and new institutional contacts.
Dr. Corby Martin has been appointed as the Associate Executive Director for Scientific Education at Pennington Biomedical Research Center. He will provide leadership for key programs such as the T32 Postdoctoral Training Program, the Pennington Scientific Symposium and the Bray Obesity Symposium.
A recent study published in Obesity found a direct relationship between obesity severity and the likelihood of disease burden in the US population. The researchers discovered that higher BMI levels were associated with increased odds for various cardiometabolic conditions, including diabetes, hypertension, and kidney disease.
Dr. Leanne Redman joins the Charles Perkins Centre to lead research on obesity, diet, and exercise, building on her extensive experience in women's health issues and translational research. With over 300 publications and numerous awards, she will expand the centre's impact on global health.