A research team has developed a new strategy to regulate quantum states in layered materials by precisely tuning atomic layer movement. This approach enables the design of superlattices and regulation of electronic properties through structural engineering.
Researchers developed a thermal catalyst with high CO oxidation activity under low-temperature conditions. By introducing dithiolate bridging ligands, the team reinforced the nanocluster's outer framework while allowing weaker ligands to be removed more easily.
The study reveals the detailed structure of an RNA–DNA hybrid G-quadruplex, showing unique arrangement and unusual structural state. The findings suggest that RDQs may participate in regulating interactions between RNA and DNA in cells, protecting telomeres and maintaining genome stability.
A new membrane-based approach for treating high-salinity brines has been developed, utilizing thermoresponsive ionic liquids as recoverable draw solutes. The system achieves stable operation under high-salinity conditions and can be regenerated using low-grade heat.
Researchers have developed a new anticancer immunotherapy technology that selectively eliminates key substances released by cancer cells and boosts the patient's immune response. This 'nanoswitch' technology uses laser therapy to reactivate beneficial extracellular vesicles that induce anticancer immunity.
A flavonoid-based fluorescent dye combined with whey protein creates a supramolecular probe that rapidly detects phoxim pesticide concentrations in solution. The system shows good selectivity and response, making it suitable for on-site screening in food safety and environmental monitoring.
Researchers found that high fever can activate the Heat Shock Response in malaria parasites, making them non-infectious. This protective mechanism may help prevent disease transmission from humans to mosquitoes.
A modular reporter phage platform has been developed to rapidly detect multiple Klebsiella pneumoniae capsule types. The platform uses a NanoLuc luciferase reporter gene and demonstrates high sensitivity and specificity, with the ability to distinguish between live and dead bacteria.
A team at Taiyuan University of Technology has developed a multi-responsive MXene-based actuator with programmable deformation and sensitivity to humidity, light, and magnetic fields. The actuator combines the benefits of MXene's high electrical conductivity and thermal expansion capability.
A groundbreaking study reveals the 1789 smallpox outbreak had a devastating demographic impact on Indigenous Australians, with estimates suggesting up to 220,000 deaths. The model confirms the epidemic originated in Sydney Harbour with the First Fleet, highlighting the catastrophic consequences of colonial invasion.
Researchers developed FeCo magnetoelectric composite nanocages with enhanced magnetic loss and wideband electromagnetic wave absorption. The nanostructures exhibit excellent EM wave absorption performance, including a minimum reflection loss of -47.4 dB and a broad effective absorption bandwidth of 7.10 GHz.
A new report reveals that 42% of people in the UK deliberately limit their AI use, primarily driven by worries about data protection. Despite the benefits, many individuals are ambivalent towards AI due to growing security and privacy concerns.
A new book identifies nine types of procrastinators, from worriers to thrill seekers, and offers strategies for overcoming the problem. Procrastination causes serious harm to finances, health, relationships, and careers, but can be overcome with the right approach.
A KAIST study found that immigration-related legislation can lead to increased toxic chemical releases from manufacturing facilities in the US. The research team analyzed data from 14,390 facilities and found a significant increase in pollution when political attention shifted to immigration.
Researchers developed a silk-based sticker that tracks temperature, pH, sodium, and glucose levels in newborns without needles or wires. The wearable patch uses AI to analyze color changes, providing accurate readings above 91% for critical vital signs.
Researchers discovered that damaged myelin generates abnormal rhythms in the sleeping brain, linked to disruptions in brain circuit stability. This finding may help design non-invasive approaches to repair myelin during sleep, improving sleep quality in patients with MS and Alzheimer's disease.
Research found that krill can clog the baleen of filter-feeding whales, slowing water ejection rates to 0.02m/s. To maintain optimal feeding speeds, whales must prevent krill accumulation on their baleen or keep it suspended in their mouths.
Japanese researchers have developed a catalyst that selectively degrades polyurethane in mixed plastic waste, allowing for the separation and chemical recycling of complex materials. The breakthrough opens up new possibilities for waste management, particularly in industries such as end-of-life vehicle recycling and mattress disposal.
A randomized clinical trial found that acupuncture to the ear (auriculotherapy) reduced migraine pain and improved its impact on daily life. The treatment showed a statistically significant improvement in oxygenation levels in the brain, but not a difference between the auriculotherapy and sham groups.
A new study suggests that a gradual approach to tapering opioid doses, putting the patient in control, can help them reduce their opioid use long-term without increasing pain. After 12 months, about half of patients achieved a successful response, defined as cutting their opioid dose by at least 50%.
A new preclinical study has identified a gut bacterium, Akkermansia muciniphila, that helps prime intestinal stem cells for faster recovery after radiation treatment. Fasting increases the population of this bacterium, which produces a small molecule that changes histone tags to allow gene expression in intestinal cells.
A new Stanford-led study confirms the primary cause of the Permian–Triassic extinction event, which wiped out 96% of marine species and 70% of land animals. The research reveals that organisms with slower metabolisms and more vulnerable conditions were disproportionately affected by warming oceans and decreased oxygen availability.
A new study published in Biochar shows that combining green manure with biochar can improve soil quality, support maize yield, and reduce dependence on nitrogen fertilizer. The research found that soil microbial diversity emerged as a central driver of improved soil quality.
Andean leaf-eared mice have evolved to survive extreme elevations with low oxygen and freezing temperatures. They can generate higher heat through shivering and process plant-derived dietary toxins.
Researchers at Tufts University developed tiny tattoo-like sensors that track temperature, humidity, and stem growth in plants. These sensors provide an early warning system for farmers, allowing them to respond before visible signs of plant stress appear.
The COCOON Lab provides a coordinated suite of microscopes that work together to connect macro-scale observations to findings at the nanoscale. This allows researchers to study biological and industrial materials in unprecedented detail, from the macroscale down to the molecular scale.
A two-year field study shows that biochar-derived from rice straw improves soil health and crop resilience to saline-sodic stress. Biochar enhances nitrogen metabolism, increases yield, and reduces oxidative stress, making it a promising strategy for sustainable rice production in salt-affected regions.
Researchers have developed a biochar adsorbent that combines physical and chemical interactions to capture tetracycline molecules. The material showed high tetracycline adsorption capacity and good resistance to coexisting ions, suggesting potential for repeated operation.
A team of researchers developed a method to control powering down catalysts, improving carbon dioxide conversion without loss of performance. The approach reduces costs by about 25% and enables reliable operation with intermittent renewable electricity.
Researchers have discovered that relativistic effects play a crucial role in the bonding of heavy elements like bismuth. The traditional picture of triple-bonded molecules does not hold true for these elements. Instead, the bonds are more complex and involve hybrid sigma-pi bonds.
A new study published in Prevention Science suggests that current prevention efforts may not be reaching enough people or providing a worthwhile return on investment. The researchers propose a more scalable approach embedded directly into systems people already interact with daily.
Researchers have developed a novel quantum material that can naturally enable the study of non-Hermitian dynamics, a phenomenon where systems exhibit unusual behaviors. The material, a magnetic topological insulator, allows for the creation of electronic networks with direction-dependent connections, enabling the accumulation of states...
Physicists at UC Irvine have developed an AI system called Autonomous Model Builder that can autonomously design theoretical physics models, helping identify promising new explanations for the behavior of neutrinos. The system uses reinforcement learning and is designed to assist human physicists in narrowing down vast theory spaces.
A new $250,000 grant will support the development of a novel therapeutic approach for sepsis-associated neurocognitive dysfunction. The treatment aims to protect the brain from inflammation-related damage during and after sepsis, potentially preventing or slowing neurodegeneration and cognitive decline.
The Sunrise III mission has provided a treasure trove of data on the Sun's dynamics, revealing new insights into its quiescent state and volatile behavior. The observatory captured image sequences at intervals of about a quarter of a second, revealing structures as small as 50 kilometers in size.
A new study by Mount Sinai researchers has estimated that Phelan-McDermid syndrome affects approximately 13.7 cases per 100,000 people, equivalent to about 1 in 7,300 individuals. The condition is a rare genetic disorder caused by deletion or mutation of the SHANK3 gene and often co-occurs with autism spectrum disorder.
Researchers developed microparticles that infiltrate stubborn bacterial matrices and release tiny oxygen bubbles to clean surfaces and wounds efficiently. The particles were shown to effectively clean surgical instruments and infected wounds, accelerating healing and reducing inflammation.
The Robert A. Winn Excellence in Clinical Trials Award Program is training a new generation of physicians to solve healthcare's representation challenge through immersive education and mentorship. The program has grown rapidly, drawing hundreds of applicants annually from medical schools across the country.
A national study found that pediatric mental health treatment patterns rebounded and exceeded pre-pandemic levels, driven by new patients seeking care. Antidepressant prescriptions rose significantly among girls, with a notable increase in the youngest children.
A single monitoring network developed by McGill University and partners detected multiple types of data in the Lower St. Lawrence, including underwater earthquakes, whale calls, ship noise, and tidal activity. The results show potential applications for conservation and marine policy.
A new book reveals Iran's government failure to address devastating environmental catastrophes, while persecuting campaigners trying to raise awareness. The country's rulers have failed to provide a comprehensive plan, despite the concerning state of its natural environment, leading to issues like water scarcity and deforestation.
A new study found that increased transparency through EU regulations has led to more stakeholder criticisms of companies' environmental and social practices. As a result, companies are under greater scrutiny to maintain responsible business conduct and close the gap between their actions and public expectations.
A recent study by Suhnyoung Jun and Sepideh Sadaghiani found that the brain operates on multiple parallel streams, each with its own character, unfolding independently of others. These separate processes are governed by shared spatial and temporal principles.
The University of California, San Francisco is launching a novel clinical trial to test a combination of therapies for the most common form of Alzheimer's disease. The trial will enroll up to 825 participants and test drugs that target both amyloid and tau proteins, with the goal of slowing disease progression.
Researchers found that yeast-based supplements can reprogram early-stage immune cells to produce enhanced anti-tumor responses. The study suggests a potential solution for obesity-related immune dysfunction and cancer, using a food-grade supplement with an excellent safety record.
Baylor researchers developed a novel method of somatic gene editing in mice to generate tumor models. The new rat models closely mimic human disease biology, response to therapy and immune microenvironment, offering a powerful way to study cancers not well studied in mouse models.
A new study found that women with unmedicated depression may struggle to regulate body temperature in hot weather, but those taking SSRIs respond similarly to healthy individuals. The research suggests that SSRI treatment can help depressed women tolerate heat stress more effectively.
New research proposes a new model for understanding mud volcano behavior, revealing that large flows grow progressively through repeated small events. A hidden layer beneath the surface acts as a lubricant, allowing overlying mud to slide slowly, reshaping the landscape in ways not immediately visible.
A study by Universitat Rovira i Virgili analysed 29 substances in commercial products sold in Tarragona, finding that phthalates were the most prevalent contaminants, especially in hake dishes. The risk assessment concluded that levels detected do not pose a significant health risk.
A large dengue outbreak in Italy was analyzed to identify transmission patterns. The data show that more than half of linked transmission events involved people within 100m apart. Temperature played a role in reducing transmission, with a drop in autumn temperatures contributing to the decline.
Researchers at ORNL developed a novel electric motor drive design that cuts neutral-point current and common-mode voltage to reduce excess heat and premature wear. The approach achieves a 90% reduction in neutral-point voltage fluctuations and a 43% drop in capacitor current stress, improving system reliability.
Genital herpes is a viral infection that establishes a lifelong infection by entering nerve cells and can be relieved with medication. Researchers have identified glycoprotein G as a promising target for a future vaccine, which could provide protection against HSV-2 spread to the nervous system.
Boston University's T32 program in lung science receives a 5-year grant to train pre-doctoral PhD students and postdoctoral MD/PhD fellows in advanced areas of lung research. The program focuses on integrating basic and clinical sciences to diagnose and treat lung diseases.
A team of psychology researchers found that children aged five to nine frequently endorsed their group's claims even when evidence suggested otherwise. However, incentivizing them to tell the truth under private conditions reduced partisanship. The study suggests that group affiliation influences children's responses and offers insight...
Researchers used satellite images to study Adélie penguin colonies across Antarctica over a 30-year span, finding that those with more sea ice ate more fish, while those with less sea ice relied on krill. This trend linked to long-term changes in penguin populations, with colonies relying on krill-based diets facing decline.
Kessler Foundation has been recognized as one of NJBIZ’s Best Places to Work in New Jersey, marking the 13th time since 2012. The Foundation's commitment to fostering a collaborative culture and supporting employees has earned it a place on the prestigious list.
A study by Penn State researchers found that certifying third-party repair services increases repair rates and helps brands retain market share. By signaling the value or 'unused utility' left in broken products, certified brand repair services increased repair leads with a 700% increase.
Researchers at the University of Michigan found that pollinators are driving plant adaptation in morning glories, leading to a steep decline in their ability to adapt to changing climate conditions. The study suggests that human activities such as pesticide use and habitat destruction have contributed to this decline.
Researchers at St. Jude Children's Research Hospital discovered that C1 neurons in mice modulate fear and anxiety, with prolonged activation leading to heightened anxiety. Inhibition of these neurons reduced anxiety-like behaviors, suggesting they may be a valuable therapeutic target for anxiety disorders.
A new study analyzes geographic biases in telemetry research, finding that most studies are conducted in politically stable, English-speaking countries with high conservation funding. The research emphasizes the need for in-country capacity sharing and collaboration to ensure biodiversity hotspots are not left understudied.
Researchers identified a specific pocket within ERG and developed a small molecule probe, PBITE-1, that can bind to it. This breakthrough allows for the targeting of ERG in prostate cancer cells, potentially leading to personalized therapy.
Researchers uncovered previously undetected slow slip events in Parkfield, California, and found that these silent fault movements systematically follow increased low-frequency earthquake activity. The discovery suggests that slow slip may play an important role in how stress evolves along active faults.
Afzalbek Fayzullaev, a second-year Boston University medical student, has been awarded the ASTRO Medical Student Fellowship Award to conduct an eight-week mentored research project in radiation oncology. He aims to investigate the readability of patient education materials and their impact on treatment adherence.
A Dartmouth study reveals that people's gaze patterns in new environments contain unique personality preferences. The researchers used eye-tracking data to model individual gaze patterns and create machine-learning models that could distinguish between participants based on their conceptual themes.
This issue of Perspectives in the Arts and Humanities Asia delves into various aspects of culture and identity in Asia, including literary and performing arts, visual media, and spirituality. The journal features papers on Hui Muslims, Pacific War fiction, and selected essays of Fernando Zialcita.
A recent study overturns the idea that flowering plants didn't evolve large fruits and seeds until after the mass extinction of dinosaurs. The research found that these modern reproductive strategies may have emerged much earlier, around 74 million years ago.
Researchers at UCF developed a new technology to improve the performance of vibratory sensors, which convert vibrations into electronic signals. The SHIELD project aims to create more reliable sensors that can withstand harsh environments, enabling applications such as navigation systems and aerospace systems.
Researchers used structured light from quantum optics to transform Boehm's brushes into brighter patterns, improving their detectability. This technique may help diagnose retinal diseases like macular degeneration.
A team of researchers developed a programmable quantum simulator that shapes light to replicate how particles move through complex materials. The platform, called spatial light modulators, allows for the simulation of particle motion on various geometries, including closed loops and cylindrical surfaces.
A recent Phase II open-label study evaluated vamorolone in 20 steroid-naive boys aged 2-4 years with DMD, showing dose-dependent improvements in motor function. The traditional corticosteroids often cause growth stunting and other complications in long-term use.
Dr. Tim Allerton's research focuses on heart failure with preserved ejection fraction (HFpEF), a condition affecting millions of Americans. His team aims to determine how declining hydrogen sulfide levels contribute to muscle function and exercise capacity in patients with HFpEF.
Researchers at ESA's Annual Meeting will present new findings on the ecological effects of fire across forests, rangelands, peatlands and urban natural areas. The studies examine changing fire regimes, post-fire recovery, wildlife responses and the ecological effects of smoke, ash and fire retardants.
Researchers developed a flapping-wing robot that can fly through the air and swim underwater, studying how birds adapt to life in two radically different environments. The study found that smaller wings increase underwater speed but do not improve swimming efficiency, suggesting reduced wing size enhances maneuverability.
A new project developed by the University of Birmingham and Mind in Camden aims to improve understanding and response to people who hear voices, particularly when linked to suicidal thoughts. The resources encourage listening, curiosity, and collaboration to help individuals make sense of their experiences and feel more supported.
Biomni is an AI-powered multi-skilled biomedical research agent that designs and develops complex research workflows. It provides full citations and tracking of its work, making science more rigorous and reproducible.
The study found that collagen fibers and mineral platelets are arranged differently on the upper side of the femoral neck, making them less flexible and more prone to fractures. The researchers hope their work will contribute to a deeper understanding of bone structure and analysis methods.
A team of researchers, led by Ying Zhang, has developed artificial intelligence-driven tools to identify and attack software vulnerabilities. By teaching AI to generate proof-of-concept exploits, developers can see exactly how attackers could exploit known flaws, motivating them to fix issues before malicious actors do.
A study published in PLOS Medicine found that British Bangladeshi and British Pakistani individuals are more likely to develop multimorbidity, a condition where people experience multiple chronic illnesses simultaneously. The research identified sociodemographic and genetic factors that increase the risk of developing these conditions,...
New Cornell University research reveals that social media content creation is often depicted as a 'dream job,' but highlights the less auspicious elements of work in this space, including endemic burnout. The researchers found that creators have few mechanisms for protection from work-related harms due to their status as independent co...
The University of Texas at Arlington's Smart Hospital has been granted international accreditation by the Society for Simulation in Healthcare, recognizing its excellence in teaching and education. The accreditation reflects years of intentional effort to align training with real-world healthcare needs.
Researchers have discovered a new root response called saprotropism that guides plants away from decaying plant-derived matter. This adaptation enables roots to avoid hostile zones in soil and promotes healthy growth.
A new robot designed by MIT engineers can swim underwater and fly through the air, mimicking the abilities of diving birds. The robot's wing flapping frequency and tail angle were adjusted to enable a smooth transition from swimming to flying.
A new report from Scripps Oceanography suggests that in-ground sensors can provide reliable warnings of impending cliff collapses. The study detected movement in cliffs several hours to days prior to collapse, with one event leading to a 0.015-inch-per-day crack widening due to rain events.
A new study found that physicians tend to trust incorrect AI advice and have trouble learning from patient recovery data that contradicts it. The researchers suggest that developing strategies to increase human critical thinking and detection of AI errors is crucial for maximizing the benefits of human-AI collaboration in healthcare.
A team of geographers and climate scientists found that major drought in Samoa and Tonga forced Polynesians to migrate east into the Pacific. Climate modeling revealed increased rainfall in receiving islands and a shift in sea surface temperatures, creating powerful incentives for people to seek new opportunities.
A study published in Science reveals that high-altitude mice have adapted to extreme environments by maintaining body heat, sustaining oxygen use, and relying on unusual food sources like lichens. The findings suggest evolution is a complex process with multiple systems shifting to meet environmental challenges.
A new AI system, Biomni, autonomously performs research tasks, matching expert accuracy while requiring less time. The tool enables researchers to redirect efforts toward creative hypothesis generation and cross-disciplinary collaboration.
The Andean leaf-eared mouse, the world's highest-dwelling mammal, has evolved unique metabolic and genetic adaptations to thrive in extreme environments. These adaptations enable it to generate heat, regulate blood vessels, and detoxify poisonous plants, allowing it to survive at high elevations with low oxygen levels.
A new statistical tool, KPT, analyzes existing datasets to determine when personalized interventions outperform universal approaches. The approach consistently demonstrated broad applicability and outperformed previous methods across four datasets.
A University of Stirling-led review found that certain design elements, such as striped patterns and high-contrast colors, can contribute to visual discomfort. This can range from eyestrain to migraine, and is often more pronounced in individuals with sensory sensitivities like autism, ADHD, or dyslexia.
A recent study found that CD38, a protein associated with inflammation and aging, plays a key role in rapidly advancing periodontitis and peri-implantitis. This discovery could lead to new treatment approaches and provide insights into other inflammatory conditions, including cancer.
Researchers at LMU München have created a light-based high-throughput method to analyze individual perovskite nanocubes. The new technology allows for quality control at the single-particle level, differentiating how strongly individual particles contribute and varying within samples.
Researchers developed a new series of oxazol-5(4H)-one derivatives that function as potent and selective TrxR1 inhibitors, permanently locking the enzyme in an inactivated state. The compounds show promising therapeutic selectivity and potential for future cancer drug development.
Researchers found that nearly 90% of sharks collected from Delaware Bay were exported overseas, raising concerns about conservation goals. The study highlights the need for better scientific data and stronger oversight to ensure sustainable removals of critically endangered sand tiger sharks.
Researchers at DZNE discovered that a neuron's structure is remodeled to generate its axon, which breaks symmetry and forms a single long extension. The process occurs through a zipper-like mechanism involving Arp2/3 protein complex, driving rhythmic shape-shifting in the cell.
Fraunhofer Institute's INQUBATOR launches open call for businesses to apply with their use cases for customized solutions in collaboration with Fraunhofer partners, providing practical access to real quantum computing and support for tangible benefits. The application deadline is August 31, 2026.
The Neuroscape Technology for Aging Health - Digital Approaches (TAH-DA) longitudinal study aims to identify biometric predictors of cognitive decline over a year. Participants will use Samsung wearable technology and digital interventions to assess brain health.
Researchers developed a physics-informed scoring system to identify two-dimensional materials with unusual electronic properties. The approach captures signatures of flat-band behavior and trains a model to estimate scores directly from atomic structure, accelerating the search for promising materials.
Researchers identify a promising new strategy to overcome drug resistance in deadly brain cancer by blocking nitrosative stress. Combining BA-101 with temozolomide slows tumor growth, reduces cancer's ability to spread, and increases cancer cell death.
Researchers developed an electrothermal process for alcohol oxidation using cobalt oxide as a catalyst, achieving high selectivity and efficiency. The study shows that combining heat and electricity can increase production rates while reducing energy consumption.
Researchers from Paderborn University, along with colleagues from Berlin and beyond, have secured funding for their project on semidefinite foundations for quantum codes. The aim is to develop mathematical foundations for quantum codes, crucial for building fault-tolerant quantum computers.
Researchers at ETH Zurich have developed a new approach for quantum computing that separates computation from working memory, using mechanical vibrations to store information. This method has the potential to improve the efficiency of quantum computers and enable them to tackle complex problems more efficiently than classical computers.
Studies in Drosophila complement mammalian systems to uncover EV biogenesis and function, revealing conserved molecular pathways. The review highlights diverse physiological functions of EVs across species, including development, metabolism, immunity, and cancer progression.
Epithelial tissues behave like solids while retaining the disordered structure of liquids. The team developed an active vertex model that incorporated mechanochemical feedback to reproduce experimental signatures of glass dynamics, revealing a link between cellular mechanics, actin organisation, and collective tissue behaviour.
A study published in Cancer Cell identified a six-gene signature in microscopic colorectal cancer liver metastases that may help predict recurrence after treatment. The findings suggest these tiny tumor deposits could serve as a tissue-based marker of residual cancer cells, recurrence risk and chemotherapy resistance.
Living labs in agricultural, food and nutrition research facilitate stakeholder collaboration to identify problems and develop solutions. Long-term funding perspectives are essential for efficient and successful research.
A collaborative project between Alqem AI and the Max Planck Institute for Chemical Physics of Solids aims to identify new magnetic materials without rare earth elements. The company's AI platform combines extensive databases with high-quality training data to turn digital predictions into real materials.
Researchers from BST and IGTP are developing therapies based on extracellular vesicles, which can perform tissue regeneration and modulate inflammation. These nanoparticles could revolutionize medicine by delivering medicines directly to damaged tissues.
Haemophilia patients are at risk of life-threatening bleeding during dental procedures due to clotting factor deficiencies or inhibitor antibodies. Dentists must assess patients carefully before invasive procedures and use evidence-based treatments such as clotting factor replacement and local haemostatic measures.
Scientists used a new method to measure Earth's temperature over the Phanerozoic period, finding past temperatures were around 10 degrees Celsius above pre-industrial levels. The study suggests that natural processes have regulated the planet's climate for millions of years, and humans must take action to maintain a habitable range.
A recent study analyzed over 9,000 size changes in marine animals and found that body size decrease is a general response to environmental crises. The research suggests that warmer temperatures can lead to stronger and more variable changes in species size, posing far-reaching consequences for food chains and fisheries.
The iron cycle complements hydrogen-based power generation by providing a long-term energy storage solution. Iron powder can be transported globally with less infrastructure investment, making renewable energy usable worldwide.
A recent study reveals that astrocyte subtype dynamics play a crucial role in regulating mental health, particularly in mood disorders such as depression and anxiety. The review highlights how inflammatory signaling, metabolic imbalance, and ion channel dysfunction contribute to disease progression.
This study demonstrates the efficacy of Fufang Huangbo Formula in alleviating myeloproliferative neoplasms by inducing cell senescence, inhibiting proliferation, and reducing inflammation. Key components like forsythiaside A and chlorogenic acid are identified as active molecules targeting STAT3 and NF-κB pathways.
A systematic review found that babies born by caesarean section or exposed to antibiotics around the time of birth tend to have differences in their gut bacteria composition, with less diversity and beneficial bacterial groups less abundant. Exclusively breastfed infants appear to show a partial restoration of microbial balance.
Scientists at Institut Laue-Langevin create novel combination of neutron and light scattering to elucidate molecular structure of therapeutic nanoparticles. The technique enables precise determination of particle dimensions, internal structure homogeneity, and potential drug location.
A mechanical soft force sensor eliminates electronic components, allowing soft robots to sense and respond without power or signal processing. The sensor detects multi-axis forces and converts them directly into fluidic actuation.
A new study found that prophylactic naldemedine is a cost-effective intervention for opioid-induced constipation in cancer patients. The analysis revealed an incremental cost-effectiveness ratio of 1,445,276 Japanese yen per QALY gained, which is below the official willingness-to-pay threshold of 5 million yen.
A novel gene promoter called cmGAD67 shows promise for treating drug-resistant epilepsy by selectively stimulating inhibitory neurons. The study found that the promoter drove strong and highly selective gene expression in specific brain regions, reducing abnormal electrical activity and seizures.
The SNU Engineering team has developed an eco-friendly artificial spiderweb pressure sensor that achieves high sensitivity, fast response time, and excellent mechanical stability. The sensor is capable of real-time detection of human pulse, respiration, vocalization, and finger movements, making it suitable for Parkinson’s disease reha...
Researchers discovered that random sounds played during sleep can disrupt the consolidation of new memories by altering the composition of sleep stages. Participants who heard randomly played sounds spent less time in deep sleep and experienced poorer memory performance.
A new study identifies a rare genetic mutation in the CDK12 gene as a cause of aggressive prostate cancer at a young age. Genetic testing for this mutation could help identify families at risk and support early cancer detection, potentially saving lives.
Researchers developed a novel film by incorporating tannic acid into deacidified chitin nanofibers, achieving remarkable tensile strength, UV shielding, and antioxidant properties. The film demonstrated exceptional performance in preserving fruits, such as strawberries, for extended periods.
After Medicare expanded coverage for Wegovy to prevent heart complications in obese patients with heart disease, prescription fills jumped sharply. However, a significant fraction of eligible beneficiaries still did not receive the treatment.
A preclinical study reveals that different muscles remodel on different timelines after hemorrhagic stroke, with specific adaptations occurring between 2-12 weeks. Rehabilitation programs may need to be timed to these post-stroke windows to effectively leverage muscle plasticity for functional recovery.
A recent study found that frequent formulary rejections of single-source branded drugs in the US lead to delayed or absent treatment, highlighting trade-offs between cost and access to medicines. The study highlights the need for more affordable medication options, particularly for patients with chronic conditions.
Researchers have developed a new AI-based approach to automatically detect and classify e-cigarettes with digital screens. The tool has been trained on over 7,000 images and achieved accuracy rates of over 90%, enabling the detection of thousands of devices sold online.
Researchers at JAIST and NIMS have developed a high-throughput screening strategy that simultaneously explores catalysts and reactions. The approach resulted in the discovery of promising materials and revealed minor products, including 1-butene and benzene, indicating early signs of unknown reaction pathways.
A recent hantavirus outbreak on a nature cruise has sparked concerns about the potential for a global pandemic. Experts warn that Ebola-like viruses pose significant threats to public health.
Subjective olfactory impairment consistently associated with depression, while objective impairment linked to aging and anosmia. The study suggests partly distinct underlying mechanisms for subjective and objective impairments.
A study published in Global Change Biology found that falling water levels increase methane emissions from Mediterranean reservoirs. The research, conducted at the Cubillas reservoir in Spain, used a floating platform with eddy covariance technology to continuously measure greenhouse gas emissions.
A cohort study of California public high schools found that dedicated health courses were associated with modestly lower prevalence in several common forms of adolescent substance use. The study suggests that sustained, dedicated health coursework may be a scalable component of school-based substance use prevention.
A new study found that seagrass meadows are a vital source of nutritionally rich fish for coastal communities, with an average seagrass fish providing up to 21% of a child's daily zinc needs. Seagrass meadows are essential habitats for supporting the health and well-being of millions of people in tropical coastal regions.
A new genus of giant salamander, Limnospondylus ajimuensis, has been identified from fossilized vertebrae found in the Ajimu region of Japan. The discovery sheds light on Japan's evolutionary history and highlights the importance of preserving extant species for the future.
A study published in Psychology of Violence found that school administrators experienced verbal and threatening aggression from parents, with nearly 3.5 times the rate reported by teachers. The researchers recommend implementing tiered systems of support for all school personnel to foster a healthier climate.
Recent studies validate AI-based chatbots as effective alternatives to human fitness professionals for generating personalized training programs. However, limitations in nuance and continuous monitoring require hybrid models combining AI tools with human expertise.
The Center for BrainHealth has partnered with Dr. Krystal Sexton to expand its workplace-focused strategy, providing science-based tools to optimize workforce performance and resilience. The partnership aims to equip organizations with scalable solutions to enhance adaptability, innovation, and long-term performance.
A new study by University of Technology Sydney researchers suggests that honesty can be more efficient than incentive contracts in organisations. By modeling principal-agent relations, the authors show that trust and professional integrity may outperform performance-based pay, potentially eroding trust over time.
Researchers at HZB developed a novel perovskite triple-junction solar cell with a GO/SAM bilayer, achieving an efficiency of 27.3% and retaining over 90% of its original efficiency after 770 hours. This study demonstrates the potential of all-perovskite multi-junction solar cells for high power conversion efficiencies.
Acute myeloid leukemia (AML) is classified into 16 subgroups based on its epigenomic features, each with unique clinical prognosis and drug sensitivity. Epigenomic analysis reveals an additional dimension of AML diversity beyond gene mutations alone.
A new study found that over 50 million Americans live in counties without a radiation oncology clinic, highlighting vulnerabilities in the nation's cancer care infrastructure. Radiation oncology practices have closed disproportionately in rural areas and freestanding settings, raising concerns about patients' access to cancer care.
This cohort study found that TCM syndrome differentiation-based treatment improved clinical outcomes and reduced TCM symptom scores in patients with post-COVID-19 syndrome. The study showed favorable efficacy across subgroups, with a higher effective rate in the treatment group compared to the control group.
Researchers have discovered stellar cocoons rich in complex organic molecules within a supernova remnant, indicating that newborn stars can remain protected and preserve their molecular composition. The study suggests that the environment of our Solar System's formation may be more diverse than previously recognized.
An international team led by Juan Diego Soler has produced the sharpest maps ever made of neutral hydrogen in the Orion Nebula, revealing giant expanding shells and mysterious elongated structures. The findings suggest that the Orion Nebula has been shaped by multiple episodes of stellar feedback rather than a single expanding bubble.
This ecological study identified hemolysis-associated disorders as major drivers of the escalating global PAH burden. Hemoglobinopathies and hemolytic anemias correlated positively with PAH incidence, with G6PD trait, other hemoglobinopathies/hemolytic anemias, and vitamin A deficiency identified as top predictors.
Dr. Joe Northup, a renowned metabolic and bariatric surgeon, has been elected the 40th president of ASMBS. He aims to ensure patients understand the role of surgery in comprehensive obesity care.
The STEM-PD trial demonstrated the safety and feasibility of stem cell-derived dopaminergic cell transplantation in patients with moderate to advanced Parkinson's disease. The findings mark an important step in evaluating this approach as a potential treatment strategy for neurodegenerative diseases.
Early signs of clinical improvement have been observed in patients with treatment-resistant systemic sclerosis treated with investigational stem cell-derived CAR T-cell therapy, known as FT819. The therapy has demonstrated a reassuring safety profile and has the potential to expand access to patients who might otherwise face barriers t...
A genetic study has identified a link between irritable bowel syndrome and lipid metabolism, specifically triglyceride regulation. The research found that variations in the GCKR gene play a key role in this connection, highlighting a new approach to treating IBS
A Phase 1/2a clinical study demonstrates long-term survival of transplanted human neural progenitor cells in patients with retinitis pigmentosa, maintaining a favorable safety profile. Visual acuity remained stable, and imaging showed cells remaining present in the subretinal space for at least one year.
Researchers have found that GLP-1 agonists can normalize genetic pathways involved in pulmonary fibrosis, a lung disease associated with Long COVID. The treatment has shown promise in reducing the risk of fibrous buildup, suggesting potential benefits for people with type 2 diabetes and severe COVID-19 symptoms.
Research suggests that infrasound is registered in the inner ear through different sensory hair cells and electrical potentials, leading to varying perceptions among individuals. This discovery may help explain why some people are bothered by low-frequency noise while others are not.
Researchers at ISSCR 2026 present interim clinical findings from the first Phase 1/2a trial of autologous iPSC-derived dopamine neuron precursor cells for Parkinson's disease. The approach uses each patient's own cells, and new genomic quality control methods ensure the manufactured cells are suitable for transplantation.
The REGEN4HD study marks a significant milestone in the development of regenerative medicine approaches for Huntington's disease. The Phase 1b/2a trial enrolls early-stage symptomatic patients to evaluate safety and tolerability.
Researchers present new insights into an iPSC-derived neural progenitor cell therapy for chronic ischemic stroke, demonstrating safety and biological activity over extended follow-up. The findings have the potential to expand treatment options for patients living with chronic stroke disability.
A new study published in the Annals of the American Thoracic Society found that nearly one-third of COPD patients demonstrate unacceptable inhaler technique, leading to smaller lung function improvements. Instructing patients to hold their breath for 5-10 seconds improves acute bronchodilation.
The center aims to address the structural gap in care delivery by offering advanced functional diagnostics, individualized treatment planning, surgical intervention, and long-term management. Led by Professor Sungsoo Park, it provides objective, precision-based diagnosis and tailored treatment strategies for patients with refractory GERD.
Researchers at the University of Pennsylvania and Chinese University of Hong Kong created TD3B, an AI framework guiding peptide generation toward candidates predicted to have a desired effect. The tool predicts binding likelihood and determines activation or deactivation of associated cellular machinery.
Researchers developed antifungal nanoparticles from human immune cells that target Candida albicans, reducing fungal growth and improving survival rates in mice. The nanodiscs physically damage fungal cells and boost the body's natural immune defenses.
A recent study finds that individuals experiencing food insecurity prefer telehealth abortion services due to cost savings and avoidance of secondary expenses. The study reveals that nearly 50% of those in food-secure households opted for telehealth abortion primarily due to its lower cost.
The partnership aims to streamline prior authorizations, appeals, and financial assistance, addressing delays or denials in accessing prescribed therapies. By combining AGA's clinical leadership with Forus's medication access platform, the collaboration seeks to enhance patient advocacy and access to effective treatments.
Esprit's frameless mask-based system reduces patient discomfort and psychological stress through submillimeter accuracy and real-time motion management. The AI-powered Lightning treatment planning software streamlines workflow, reducing planning time by up to 80% and enhancing protection of critical normal structures.
A landmark study has shown that transplanting stem-cell derived dopamine progenitor cells into the brain is feasible and safe. Eight patients received the transplanted cell product, with no serious side effects observed during the first year of follow-up.
Study identifies binding pocket on sodium ion channels where anesthetics like sevoflurane stabilize in inactive state, reducing neuronal activity. The findings may enable the design of safer, more selective anesthetics with fewer side effects.
Macrophages are critical drivers of chronic allograft failure, with emerging strategies targeting key macrophage signaling pathways providing an important conceptual shift. Targeted therapies, such as inhibiting the purinergic pathway and mTOR/NF-κB pathway, show promise in preventing chronic rejection.
A new study reveals that lung tumors can cause cachexia by hacking into the nervous system and altering eating behavior. Researchers found that tumors missing a gene called LKB1 produced prostaglandin E2, a signaling molecule that amplifies inflammation and causes weight loss.
Researchers demonstrate reversible switching of helimagnetic order by manipulating the polarity of an electric current under an applied magnetic field. The study provides a principle for controlling complex magnetic order using electric currents, advancing fundamental understanding of helimagnets.
Researchers at Tokyo University of Science found that revealing visual elements sequentially and matching each element with the speaker's narration improves attention and learning. Participants in a cumulative presentation format showed higher test scores compared to whole-slide presentations.
A study by scientists at CNIC and UCLA reveals that mitochondrial calcium controls interaction between mitochondria and cellular fat stores. This regulation opens potential avenues for treating obesity and metabolic diseases.
Researchers found basking shark denticles are massive and arranged in 'paver blocks,' allowing for stretching during filter feeding. This unique arrangement may promote flexibility and repel parasites.
A new study reveals that household members who work together and have a champion for solar adoption are more likely to install rooftop panels. The research found that greater support from all household members predicted eventual adoption, while disagreement was linked to a higher likelihood of installing solar.
Research reveals multifloral honey's protective effects on human skin cells from UV radiation, promoting cell recovery and preventing aging. The study found that honey increased stemness-related markers and reduced aging-associated genes in skin stem cells and fibroblasts.
Researchers discovered that ancient organism Spriggina floundersi preferred to bend to the right, showing the oldest known example of lateralized behavior. This finding provides new insights into the origins of left-right asymmetry in animals and suggests that behavioral preferences emerged earlier in evolutionary history than previous...
Researchers found that tiny, invisible swirls in the deep ocean shape significant climate forces like sea level rise and fisheries collapse. Climate models require significant improvements to accurately predict these effects.
The study uses the upgraded GRAVITY+ instrument to measure the carbon isotope ratio in Beta Pic B's atmosphere, but finds inconsistent results that challenge its interpretation. The findings suggest that the planet may have formed outside the snowline, where CO was present as ice, rather than gas.
A team of 23 researchers from 14 nations identifies three research priorities: winter aerosols, clouds, and feedback; winter storms and sea ice interactions; and polar-global teleconnections. These processes are highly under-observed due to their high variability and logistical challenges.
A EU research project has found that reducing average living space per person can lead to significant CO2 emission reductions in the European building sector. By minimizing living spaces, emissions can be reduced by up to 90%, meeting the EU's 2.0-degree climate target by 2050.
A recent study by the Keck School of Medicine found a decline in ADHD medication misuse among US adults, particularly among young adults. The misuse was largely driven by a shortage of ADHD medications, leading to an estimated 71.5% of patients facing difficulty filling their prescriptions.
Researchers developed gallium-doped zinc oxide nanosheets that can detect red, green, and blue light while remaining nearly transparent. These nanosheets enabled the detection of full-color images with half the error of conventional cameras, making them suitable for demanding environments like space hardware and automotive systems.
Researchers found that smelling dark chocolate odors increased training volume and suppressed hunger, while milk chocolate had no effect. The study suggests that food scents can trigger changes in body and mind similar to actual consumption.
Korea Institute of Materials Science (KIMS) has developed a plasmonic-based liquid biopsy platform capable of ultrasensitive detection of KRAS mutations in the blood and urine of patients with Stage 0 and Stage I colorectal cancer. The platform demonstrates over 90% concordance in KRAS mutation status across matched tumor tissue, plasm...