Researchers discovered a novel spiroquinoxaline compound that inhibits Cryptococcus neoformans virulence and triggers lethal oxidative stress, offering a promising new lead for treating cryptococcal meningitis. The compound, B1, shows potent antifungal activity and induces cellular damage through oxidative stress-mediated mechanisms.
Researchers used numerical simulations and isotopic data to connect hot spring magmatic water to the subducting Pacific Plate. The study found that magmatic water from Kawayu Onsen in Japan closely matched isotopic values released from the Pacific Plate at a depth of 125 km.
A new UAB trial demonstrates promising results for a novel immunotherapy in treating glioblastoma. The treatment, DeltEx DRI, has been shown to more than double progression-free survival, with median overall survival reaching up to 19.5 months.
Researchers found that clouds in sub-Neptune atmospheres actively shape their interior conditions, driving temperatures higher and potentially creating magma oceans. This discovery challenges the interpretation of James Webb Space Telescope data, suggesting clouds may be distorting our view of these planets' true bulk composition.
A team of scientists developed a dual-band hydrochromic optical modulator for multimodal anticounterfeiting and encryption. The device changes its appearance in the visible and mid-infrared regions through three modes: water-triggered visible switching, infrared emissivity modulation, and chemical signature authentication.
A team from Singapore University of Technology and Design has developed an AI agent that uses artificial intelligence to help patients make life-or-death decisions. The system, called ACPAgent, was tested with 15 participants who agreed with its recommendations in 86.7% of cases, but also showed limitations in handling high-subjectivit...
Pregnant women who engage with child protection services often experience fear, mistrust, and stigma, leading some to avoid health and support services. The study identified missed opportunities for early intervention and support during pregnancy, which could improve outcomes for mothers and babies.
A second PSMA PET scan changed treatment plans for nearly half of patients whose first scan was negative, detecting evidence of disease in 56% of cases. The study found that repeat imaging was most likely to detect disease in patients with higher PSA levels and a PSA doubling time of less than twelve months.
The partnership aims to bridge the gap between university learning and real-world practice, equipping students with in-demand digital skills. Through the Octave NextGen Builders Program, students will gain practical experience using professional tools used across industry projects.
A new multimodal fluorescence-phase microscopy (MFPM) system combines fluorescence excitation with label-free imaging, achieving precise spatial co-registration and maximizing data acquisition efficiency. This unified platform enables comprehensive biological investigations with enhanced imaging throughput.
Researchers have developed a federated learning algorithm that solves the long-standing conflict between robustness and efficiency in AI development. The new approach anonymizes data and reduces single-point failure risks while maintaining speed. By remembering past client interactions, servers can protect against malicious input.
A new study from Edith Cowan University found that a midwife-led birth debrief can significantly strengthen women's emotional wellbeing after childbirth. The structured conversation provides an emotionally safe space for women to reflect on their birth experience and find meaning, leading to high satisfaction rates.
A culturally tailored midwifery model of care has been shown to improve perinatal outcomes for First Nations babies, including a 45% increase in healthy births and higher breastfeeding rates. The study found that continuity of care with a known midwife reduces disparities in birth outcomes.
Researchers at Saitama University have developed a sequential annulation strategy to construct regioisomeric ladder-type oligothiophenes with precise control over thiophene ring orientation. This allows for the systematic synthesis of complex molecular structures, paving the way for the design of next-generation organic semiconductors.
Insilico Medicine achieved a significant revenue increase of 272.7% to 287.3% for the First Half of 2026, with net profit expected in the range of USD33.5 million to USD39.5 million. Global collaborations and strategic partnerships drove business growth, with major deals secured with top pharmaceutical companies.
Researchers at QUT and AusHSI found two widely downloaded health datasets to have unknown origins, raising questions about their authenticity and suitability for clinical research. The study assessed the datasets using the internationally recognized TRIPOD+AI reporting framework and scored 0 out of 9 on essential data-provenance criteria.
A new UNM-led study combines ancient sand grains and fish DNA to reveal the Colorado River's gradual formation between 8-4.8 million years ago through Grand Canyon. The research team found that the river emerged as a series of smaller proto-rivers linked together over approximately 3 million years.
Researchers at Gladstone Institutes found that hypoxia therapy can extend lifespan and improve brain function in mice with motor neuron degeneration. The therapy works by reducing the amount of oxygen available to cells, which can help counteract the effects of defective mitochondrial quality control machinery.
The brief connects 16 movements, from the Institute for Colored Youth to today's Student Action on Curricular Restrictions, and pairs each with evidence-grounded policy recommendations. Key patterns across generations of youth organizing include mass mobilization, coalition-building, and legal pressure.
The American Heart Association brought Hands-Only CPR training to FIFA Fan events in the US, with over 8,000 attendees participating. This effort aims to double survival rates from cardiac arrest by 2030 and educate more people on lifesaving skills.
A large clinical trial found that commonly used antihistamines and an anti-inflammatory drug, colchicine, had a small but significant benefit in reducing long Covid fatigue. However, the benefits were not sustained after stopping treatment.
New analysis reveals that most obesity medications do not meaningfully improve quality of life, cardiovascular health, or reduce mortality risk. However, some emerging drugs like tirzepatide and subcutaneous semaglutide show potential benefits in weight loss and reduced heart failure risk.
A study of over 3 million NHS births found that one-size-fits-all charts often misclassify babies, leading to missed cases and unnecessary interventions. Customized GROW charts provide more accurate data, improving safety for mothers and babies.
The European Association for the Study of Obesity, dietitian societies, and other organizations have issued a consensus statement on the use of incretin drugs in obesity therapy. Key findings include the importance of medical nutrition therapy delivered by registered dietitians to complement incretin-based therapies. The statement also...
Researchers at KAIST developed technology to automatically identify and fabricate two-dimensional semiconductors, revealing the relationship between thickness and performance. The technology enables data-driven research and accelerates the commercialization of AI semiconductors and ultra-low-power semiconductors.
Studies found that people with anorexia nervosa have high levels of LEAP2, a hormone linked to impulse control and blood sugar regulation. Higher levels of LEAP2 are associated with increased impulsivity and risk of relapse after treatment.
Two ECNP-affiliated journals, European Neuropsychopharmacology and Neuroscience Applied, have seen significant increases in citation rates. The rise reflects growing interest in the biological underpinnings of mental health, as reflected in the journal's focus on precision psychiatry.
A clinical trial has shown that setmelanotide, a new drug, can achieve significant weight loss in people whose weight has become dysregulated following treatment for a brain tumor. The treatment resulted in a 20% reduction in BMI, with participants experiencing substantial health benefits.
Researchers found that guided home-based exercise programs can be safely integrated into long-term recovery for aortic dissection survivors. The study showed no deaths, recurrent dissections, or aortic operations in either group, and improved some aspects of cardiovascular health.
Hong Wang, a senior R&D scientist at ORNL, recognized by the European Academy of Sciences and Arts for outstanding achievements. He conducts research on connected mobility systems and intelligent transportation technologies.
A new study reveals that melanoidins, dark-colored compounds formed during hydrothermal treatment, can severely damage the microbial system responsible for methane production in anaerobic digestion. High doses of melanoidins can cause methane generation to nearly stop, leading to system collapse and energy loss.
A Wisconsin lab advance has developed a way to remove liquid chromatography from peptide mapping, an essential test for determining a candidate drug's stability. This technique accelerates the process by 100-fold, allowing companies to analyze massive data influx instantly and reducing costs.
Oak Ridge National Laboratory researchers received five awards for their work on commercial vehicle operations, freight corridors, and integrated energy systems. ORNL's research also focuses on fuel economy guides, high-performance steel alloys, and computational tools for welding and manufacturing.
A new UGA study found that AI chatbots often provide recommendations that are inconsistent across generative AI platforms and may vary by sociodemographic groups. The researchers created three hypothetical scenarios of people who needed advice on emergency funds, investment portfolios, and retirement savings, which were entered into se...
A new study finds that chronic kidney disease rates in the US have remained consistent over the past decade, despite advancements in kidney-protective therapies. The proportion of Americans with kidney disease driven by diabetes has increased, while kidney disease not linked to diabetes has held steady.
Researchers developed a sawdust-based adsorbent that can remove methylene blue dye and real potato processing wastewater. The material achieved high adsorption capacities and was effective in both batch and continuous column tests.
A new Nigerian study has found widespread microplastic contamination in borehole water near the Sokoto Cement Factory, contaminating communities that rely on groundwater. The research identified common plastic polymers and health risks associated with microplastic exposure.
Researchers at KAUST have developed a system that uses tiny laser devices to generate unique digital fingerprints, verifying device identity without traditional passwords or security keys. The technology combines with AI to authenticate fingerprints instantly, offering a faster and more secure alternative for large-scale digital networks.
The International Society for Stem Cell Research convenes its 2026 Annual Meeting in Montréal, showcasing groundbreaking discoveries and emerging clinical advances. The meeting features nearly 1,300 scientific posters and presentations spanning every area of stem cell research.
A study found people with early-onset dementia experienced reduced work productivity up to 15 years before diagnosis, with average losses of $86,000 per person. The study also revealed varying productivity losses depending on the type of dementia, highlighting a need for interventions to prevent or delay decline.
A new clinical trial has reported improved survival rates for babies born with a life-threatening fetal disorder called anhydramnios. The treatment involved repeated injections of amniotic fluid into the womb, followed by kidney replacement therapy after birth. Results show that some infants have survived and thrived into toddlerhood.
A TGen-led study reveals that different dementia-related protein pathologies interact with each other in complex ways. The study found that inducing alpha-synuclein and tau before amyloid plaque deposition led to increased levels of defective proteins and exacerbated behavioral impairments.
Penn Nursing scholar Kathryn Connell argues that nursing's 'dual expertise' is widespread yet structurally invisible. She advocates for systemic reforms to support nurse clinician-scientists, who balance bedside practice, research, and personal experience.
A new study led by McGill researchers found that reducing vehicle emissions could prevent over 3,600 premature deaths in Montreal and Toronto. The policy mix includes keeping traffic levels steady and retiring older heavy-duty diesel trucks.
A new study found that climate change affects tree swallow populations in the northern US and Canada, with critical timing constraints and increased year-to-year temperature variability impacting breeding success. The research suggests that these populations are nearing a tipping point, with the greatest risk from warming temperatures ...
A new method called ATTACH identifies strong interactions between T cells and cancer-specific proteins to isolate effective tumor-reactive T cells. This approach overcomes key challenges in immunotherapy development, offering a rapid and accessible way for isolating rare immune cells.
A new study develops the first high-resolution urban air temperature dataset, providing detailed maps of air temperature across cities. This dataset helps explain why satellite-based data often overestimates heat stress and exaggerates disparities between neighborhoods.
A new study reveals that caregiving behaviors in ants are regulated by neural mechanisms that change over the course of an ant's lifetime. The researchers found two brain signaling molecules, Neuropeptide F and Allatostatin A, that act as opposing regulators of behavior, depending on the ant's internal state.
A new study found that specific gut bacteria from children with stunted growth can be passed to their offspring, causing inflammation and damage to the intestinal lining. The researchers identified Campylobacter concisus as a key contributor to this process, which may hold promise for future treatment and prevention strategies.
A new study found that hunger increases the immediate liking and physiological arousal triggered by sweetness, not just its calorie content. Long-term non-nutritive sweetener consumers exhibit heightened activity in a brain region linked to self-control, suggesting these sweeteners may help manage hedonic appeal.
A study led by Erica Heinrich highlights a critical gap in detecting and treating breathing discomfort or dyspnea in ventilated patients. Dyspnea is often hard to recognize, but carbon dioxide levels may be more significant drivers of breathlessness than oxygen levels.
A study by Boston University researchers found that CARB-X-backed projects are nearly five times more likely to advance to clinical trials, while nonfunded projects had less than a quarter advancing. The nonprofit's support led to the award of 160 patents and increased odds of life-saving products reaching patients.
A study published in The Journal of Pediatrics found that nearly half of infants with severe heart defects were born in hospitals without cardiac surgery. Transferring these babies to a cardiac surgical center sooner was associated with shorter hospital stays compared to those transferred later.
The Human Frontier Science Program has reaffirmed its commitment to global life science research, providing strategic investment and visibility for member states' research activities. The program delivers exceptional scientific quality, promotes international collaboration, and develops scientific talent.
Researchers from University of Missouri-Columbia investigated mesenchymal-epithelial transition (MET) in the uterus, a process where cells rebuild the uterine lining after shedding. MET helps restore the uterine lining quickly, but its dysregulation can lead to inflammation, lesions, or cancer, potentially affecting fertility.
A new antiseptic formulation has been developed to eliminate 99.9% of Candida parapsilosis cells, a fungus that causes serious infections in hospitals. The combination of alcohol-based chlorhexidine with eugenol and menthol is more effective than traditional 70% ethanol against this type of disinfection.
A study found that social media helped spread information during the Rolling Fork tornado, but also revealed communication challenges facing rural areas due to limited broadband access and fragmented media. Researchers suggest a need for personalized messaging strategies to address diverse community needs.
A new model proposes rethinking caregiving as a lifelong process, shaping parents' lives over many years. The 'Life Course Care Stress Model' focuses on how caregiving and its impacts unfold over time.
Researchers at UMass Amherst have discovered that grasses grow according to temperature, not light, unlike most other plants. The team used a bioluminescence imaging system to study the growth of purple false brome and found that temperature influences grass growth in complex ways.
Dr. Susan Culican will join a year-long program in Washington D.C., immersing herself in health policy and serving as a senior advisor to federal government leaders. She aims to bridge healthcare experience with policymaking to improve care through evidence-based policy reform.
A new study reveals how generic electron interactions in 3D cubic lattices lead to Weyl topological superconductivity. The researchers found that repulsive electron interactions create a chiral d+id pairing state with an octupolar component, featuring eight gapless Weyl points.
A study in Carlos Botelho State Park, Brazil found that brown howler monkeys rest more on hot, long days when feeding on leaves. The group traveled an average of 531 meters per day, influenced by interactions with other primate species like southern muriquis and capuchin monkeys.
Researchers found that variable-rate seeding (VRS) can help farmers strike a better balance in corn and soybean fields. However, soybeans proved to be more complicated due to their adaptability to weather conditions. The study aims to make farming more accessible and efficient for small land holders using digital tools and data-driven ...
Researchers identified nine typical disaster chain types driven by endogenic and exogenic dynamics, highlighting the need for interdisciplinary integration to understand complex geological disaster chains. The study also emphasizes the importance of 'multi-critical phase transitions' in understanding dynamic processes of disaster chains.
Researchers discovered that ancient farmers used animals like turkeys as biological 'protein concentrators' to access concentrated maize-derived lysine, allowing for high-quality animal protein. This groundbreaking study suggests that maize cultivation and animal management developed together much earlier than previously recognized.
A new study of nearly 1,500 pregnant participants found that following dietary guidelines may reduce exposure to many environmental chemicals from food and everyday products. However, the same dietary pattern does not lower exposure to all chemicals, with higher levels found in certain pesticides on fresh produce.
A study analyzing 60,000 records of flooding, waterlogging, flash floods, landslides, storms, and droughts in Brazil reveals regional impacts. The Northeast had the most affected cities, with landslides and droughts affecting this region the most.
Research shows that road verges with heavy traffic can be deadly for bumblebees, while those with low traffic have a mortality rate of near zero. The study suggests investing in species-rich road verges may not replace traditional conservation habitats.
Researchers have developed a new CRISPR-based method to control protein production in cells by targeting ribosomal RNA. This method, known as TAPIR, has been shown to increase protein synthesis and promote the growth of cancer cells. The results offer new insights into stem cell biology and disease-relevant processes.
A team of University of Oklahoma researchers has developed a noninvasive imaging approach using polarization-sensitive optical coherence tomography (PS-OCT) to evaluate donor livers more comprehensively. This technology could help transplant teams make faster, more informed decisions about liver suitability for transplantation.
Breast cancers diagnosed during the first three years after childbirth are biologically more aggressive than similar cancers in women who have never given birth. The Oncotype DX Breast Recurrence Score suggests biological features associated with a higher risk of recurrence among these patients, including higher-grade tumors.
A new analysis by Ohio State University researchers suggests that expanding energy infrastructure can boost community employment and reduce fossil fuel emissions without significant cost increases. The study's scenario-based framework revealed that even expensive policies taking community health concerns into account are only 0.7% more...
The Bob Woodruff Foundation has granted Boston University Chobanian & Avedisian School of Medicine a one-year grant to expand the Women Veterans Network, providing peer support to women veterans. The funding also supports Strength at Home Couples, a program that enhances intimate relationships and prevents conflict in military couples.
A new study reveals that Amazonian communities use at least one-third of the region's known plant species, totaling 5,796 species. Climate change is expected to lead to a decline in biocultural heritage by 26% from 2060 to 2080, threatening Indigenous cultural identity and ecosystem services.
A Phase III clinical trial is underway to develop a safe, effective, and globally accessible therapeutic for dengue. The trial, led by DNDi, involves 1,000 participants across Brazil, Malaysia, and Thailand. Monoclonal antibodies, currently the most advanced dengue treatment candidates, are being tested.
Research suggests alcohol interacts with Alzheimer's-related brain circuits in distinct ways, depending on the type of pathological change. Alcohol reduced communication in amyloid-beta models but increased it in tau models, highlighting an important principle in biology.
Scientists from Stellenbosch University have isolated a new species of soil bacterium, Dedyshia acidiphilia, from the Kogelberg Nature Reserve. The discovery provides significant advances in understanding rare bacterial species contributing to soil health and nutrient cycles.
A new study finds that a slowing Atlantic Ocean current will strengthen powerful storms in California while reducing snowfall over Greenland. The Atlantic Meridional Overturning Circulation's weakening is projected to increase atmospheric moisture and high-altitude winds, creating more destructive atmospheric rivers.
A newer 'climate-friendly' refrigerant used in car air conditioning systems may already be a significant source of a 'forever chemical' pollutant across Europe. HFO-1234yf is contributing to increasing levels of trifluoroacetic acid (TFA) in the atmosphere, which can form TFA and has been detected in water, plants, food, and human samp...
A study tracking 1,500 residents found that infrastructure within 500 meters of home encourages active transportation. The presence of bike lanes was a key factor in keeping people active and promoting cycling. The expansion of bike lanes and parks has encouraged physical activity and public health benefits in São Paulo.
A new study proposes that chondritic asteroids are escaped satellites from chaotic final stages of planet formation. These mini-moons concentrate and confine molten mineral droplets, forming asteroid-sized bodies that become the parent bodies of chondrite meteorites.
A new study reports that forty percent of women with ovarian cancer only receive a diagnosis after an emergency hospital admission. Women diagnosed through this route are four times more likely to die within two months of diagnosis.
A recent report from the American Cancer Society reveals an urgent picture of a growing global cancer burden. Nearly 21 million people were diagnosed with cancer and 9.8 million died from the disease globally in 2024, with the number of cases projected to reach 34 million by 2050.
Two studies found that California gray wolves primarily eat cattle, with 72% of scat samples containing cattle DNA. Elevated cortisol levels in cattle grazing near wolf packs also indicate chronic stress, affecting their physiology and potentially production rates.
Researchers have discovered a biomarker that can predict and prevent epileptic seizures by detecting a period of neuronal silence before the seizure occurs. The use of this biomarker in neuromodulation therapy has shown promise in reducing seizure duration by up to 93%.
Researchers at McMaster University have developed a targeted approach to treating IBD using bacteriophages, which selectively target harmful bacteria without disrupting the gut ecosystem. The phage therapy significantly reduced gut inflammation and enhanced the effectiveness of steroid treatments.
Research reveals that digital romances can mimic human stages, including exploration, emotional connection, break-ups, and even simulated weddings and pregnancies. Participants shared intimate details and attributed autonomy to their AI partners, raising concerns about privacy and data protection.
A recent study led by the University of Zurich reveals that higher intergenerational educational mobility is associated with significantly higher innovation output in Europe. This association has significant implications for education and economic policy.
A new study finds that higher education and income have varying health benefits across different racial and ethnic groups in the United States. For non-Hispanic Black participants, higher educational attainment was only associated with a 4% reduction in type 2 diabetes prevalence, while higher income was linked to increased obesity rates.
A recent study found that over half of NYC's free-roaming cats are infected with zoonotic parasites. Young male cats, in particular, act as 'super-shedders' of roundworm (Toxocara) eggs, posing public health risks.
A previously unknown species of venomous pit viper has been discovered in the eastern Himalayas, specifically in Medog County, China. The new species, Ovophis medogensis, possesses distinct physical and genetic characteristics that set it apart from its closest relatives.
A new study finds that human cortical neurons have remarkable computational capabilities, surpassing those of other mammals. The researchers developed a new method to measure the complexity of individual neurons, revealing their sophisticated computing power.
A systematic review and meta-analysis found two air pollutants associated with an increased risk of Parkinson's disease. The study suggests that long-term exposure to fine particulate matter (PM2.5) may interact with genetic susceptibility, leading to oxidative stress and neuroinflammation.
A new white paper by 135 EU researchers highlights the decline of wild pollinators, threatening food security and societal functions. The report calls for policy coordination and education on ecosystems and pollinators to reverse the trend.
Researchers discovered natural sulfur and carbon emissions from metamorphic rocks contribute to cooling spikes, while carbon remains in the atmosphere for centuries, influencing ancient ecosystem reorganizations. These findings shed new light on mass-extinction events, such as the Ordovician, Devonian, Permian, and Triassic Periods.
The EU-funded Sister Projects have released a joint white paper calling for strengthened EU action to protect and restore Europe's wetlands. The paper highlights the importance of wetlands in providing essential services such as water purification, flood regulation, and biodiversity support, while also identifying four strategic priori...
Researchers analyzed DNA samples from foraging honeybees, hive workers, and their honey to understand plant-microbe interactions in honeybee ecology. The study found that these complementary sources provide distinct insights into the complex relationships between plants, microbes, and honeybees.
A study suggests geoengineering methods like marine cloud brightening could reduce the impact of extreme weather events during a super El Niño. By targeting natural variability, geoengineering could provide shorter-term benefits with less sociotechnical risk.
Researchers found that beavers are widespread in tidal wetlands and create deep pools of water at low tide, providing habitat for threatened species like Chinook salmon. The study expands the known habitat distribution of beavers and highlights their potential role as ecosystem engineers in estuaries.
The Indian government's plan to blend petrol with ethanol aims to reduce carbon emissions and oil imports, but may compromise on food security, water usage, and sustainable land use practices. The study highlights the need for a more balanced approach to biofuel policies that considers these trade-offs.
Researchers used CRISPR and AI to identify two novel drug targets for psoriasis: the oxytocin receptor and ALOX5 enzyme. Topical gels containing these compounds reduced inflammation in mice as effectively as widely used injected therapies, offering a promising new approach to treating moderate-to-severe disease.
According to a new study published in PLOS One, people with a history of criminal legal involvement have higher odds of visiting an emergency department, particularly for substance use and mental health reasons. The authors conclude that CLI history should be recognized as a social determinant of health shaping patterns of ED use.
A recent study reveals that over 90% of the Mar Menor's key nutrients degrading the ecosystem come from recirculated underground flows, not traditional sources like streams or groundwater. This discovery highlights a previously overlooked pathway of contamination and its impact on eutrophication episodes.
The Spanish University System (SUE) saw a 95% increase in publications from public universities between 2015 and 2024, with a record year of 74,846 publications in 2021. This growth is attributed to improved faculty productivity, with public universities exceeding one article per faculty member.
Researchers modeled key physical characteristics of biological tools to understand their diversity, finding that shape affects trade-offs between efficiency and resistance. The analysis revealed optimal cone shapes for puncture tools, including those resembling scorpion's stingers and shark teeth.
Researchers have discovered fragments as small as 5cm in size in geosynchronous orbit, shedding light on their behavior and highlighting the need for more accurate surveys to mitigate damage to expensive satellites.
A study by HSE University found that younger users and those in Moscow and St Petersburg are more likely to fact-check information online. The researchers also discovered that middle- and high-income users are more likely to question the accuracy of content they encounter, highlighting digital inequality.
A new international paper argues that science alone is not enough to protect coral reefs, which are disappearing at an unprecedented rate due to climate change and human activities. The authors propose using artistic expression and creative design to inspire public awareness and meaningful action for coral reef conservation.
Researchers have developed a new tool to screen genes involved in human development at unprecedented scale and speed. The method, using organoids from human pluripotent stem cells, revealed new insights into human brain development, including the role of ZIC2, SOX11, and ZNF521 genes.
In California's human-dominated landscape, gray wolves predominantly feed on cattle, followed by mule deer and small mammals. This dietary composition suggests that coexisting with humans may be complex for wolf populations.
New research has identified genetic mutations involved in congenital cerebral ventriculomegaly, a condition where brain fluid-filled ventricles swell due to hydrocephalus. The study links CCV to neurodevelopmental disorders and positions it as an early neuroimaging correlate of autism risk.
The partnership aims to identify and develop quantum materials that will power the next generation of computing, sensing, and energy technologies. By combining world-class researchers from Rice University and Max Planck Society, the collaboration seeks to accelerate discovery and create lasting global impact in sustainability and energ...
A SUTD study reveals that factors beyond temperature affect comfort at home. Residents who spent more time outdoors reported greater comfort without air-conditioning, while closed windows and blocked airflow contributed to warmer rooms. Practical advice is needed to help households understand these influences and make informed decisions.
Researchers develop a new strategy for producing negative thermal expansion (NTE) materials, enabling safer and more efficient synthesis. The approach combines reverse coprecipitation with oxidation in a single step, eliminating the need for harsh chemicals and reducing environmental impact.
A new study explores an FMQA-based optimization framework for RNA design, revealing that encoding matters in achieving optimal results. The approach identifies high-quality RNA sequence candidates with relatively few evaluations, outperforming competing methods.
A new study from the University of Copenhagen shows that exercise plays a crucial role in improving cardiovascular health even after significant weight loss. Participants who exercised developed healthier blood vessels and lower inflammation compared to those who relied on medication alone.
Scientists at Hackensack Meridian Health's CDI Lab published two companion papers explaining the 'exhaustion' of key immune cells. The first paper identified Id proteins as determinants of exhausted CD8+ T cell fate, while the second paper revealed CTCF's role in dynamic enhancer activation and invariant barriers.
The WAG-H5-2#2508 demonstrated accuracy within stated uncertainties, closely matching manufacturer specifications and rivaling established laser gravimeters. Its long-term stability was also confirmed, enabling continuous, unattended monitoring and supporting hybrid gravity observation networks.
Chikungunya fever is caused by the Chikungunya virus, transmitted by Aedes mosquitoes. Traditional Chinese medicine offers promising integrative treatments, particularly for acute symptoms and chronic polyarthralgia. A holistic response to CHIKV requires combining standard care with evidence-based TCM.
Two research teams from Rice University and Houston Methodist are awarded grants to study protective effects of metal nanoclusters against radiation-induced skin injuries and explore the role of m6A in leukemia cell growth. The collaboration aims to improve cancer care and outcomes through innovative, interdisciplinary proposals.
Researchers from Universitat Oberta de Catalunya found that robot adoption increases productivity in Spanish SMEs, especially smaller firms with fewer workers and less innovation. However, introducing robots does not directly translate into increased international business activity, as regional specialization plays a key role.
Understanding plant microbiome interactions could transform crop production and improve sustainability. Researchers are exploring how plants shape their microbial partners to acquire nutrients, defend against disease, and respond to environmental stresses.
Researchers developed an AI assistant called ChatHEA to guide the discovery of new catalysts for clean energy technologies. The team screened and evaluated 100 five-element high-entropy alloy catalysts, finding that FeCoCuPtIr showed excellent oxygen reduction activity and durability.
Researchers from Institute of Science Tokyo have created a compact 300-GHz-band 4×4 bi-directional phased-array transceiver in 65-nm CMOS, achieving significant advancements in 6G wireless communication. The transceiver operates over 240–270 GHz and consumes only 26 mW per element.
Encellin reports non-fibrotic engraftment and host vascularization in Phase 1 trial participants, building on interim results. The findings support the company's approach to deliver cell therapy safely and durably without immunosuppression.
Research on ocean acidification's impact on cephalopod brains reveals a 49% reduction in brain volume compared to controls. The greatest reductions were found in visual information-interpretation regions, correlating with significant feeding behavior changes.
Hawaii's songless crickets have rapidly evolved to overcome reproductive challenges caused by lack of courtship songs. Non-singing males develop faster than wild-type males, allowing them to seek out female mates using alternative methods.
A recent study by Oregon State University suggests that animals don't necessarily flee in search of better breathing conditions when exposed to wildfire smoke. Instead, they may shift their behavior to reduce the negative impacts of smoke inhalation.
A collaborative research team led by HKU Dentistry has mapped noma incidence risk across 296 local government areas in Nigeria, revealing previously unrecognised high-risk areas. The study provides a comprehensive small-area assessment of noma risk in Nigeria and offers implications for public health.
New study redefines the existence of necks in fish and amphibians, identifying functionally distinct anatomical regions. The project aims to build new definitions that apply more widely across all major vertebrate groups.
Research on burying beetles found that heat stress leads to an increase in same-sex mounting, contradicting initial assumptions. The study suggests a possible trade-off between heat-protection and social communication cuticular hydrocarbons may be involved.
A new study reveals that summer concurrent hot and dry events in China intensify due to different physical driving mechanisms in western and east-central regions. Western China's trends are driven by anthropogenic warming, while east-central China's hazards stem from coupled monsoon decline, drought amplification, and heat feedback.
Researchers developed an aerated hydrogel that allows air to pass through while maintaining its water content. This breakthrough enables longer-lasting products, such as breathable bandages, implants, and wearable sensors, with improved skin comfort and reduced sweat buildup.
A study by John Innes Centre researchers reveals that inner tissues play a crucial role in shaping plant organs, contradicting the widespread assumption that external layers control growth. By analyzing cell division orientation and gene editing techniques, they discovered genes affecting stem thickness in Arabidopsis.
This cohort study of 38,535 singletons found that birth weight decile was associated with early-life growth patterns. The use of birth weight decile group may help identify high-risk children missed by conventional thresholds.
Scientists at CUNY ASRC successfully amplify electromagnetic waves by simulating ultrafast rotation, recreating Penrose-Zel'dovich process. This breakthrough enables experimental studies of extreme rotational dynamics and opens new avenues for wireless communications and optics applications.
A new study by researchers at the University of California, Santa Cruz, reveals that multipotent progenitors, 'parent' blood cells, protect blood cell production and function from aging effects. The findings confirm the safety of bone marrow transplants from older donors.
Researchers at UC San Diego successfully performed two surgeries using teleoperated humanoid robots, called Surgie, which have real potential for amplifying access to critical surgeries. The compact robots can be deployed in remote areas and are easier to use than specialized robotic systems.
Depression is associated with a greater tendency to be reinforced by social rewards on Twitter, contrary to laboratory-based findings of blunted reinforcement learning in depression. This suggests potential mechanisms linking social media use to worse mental health outcomes.
Between 2003 and 2024, annual US deaths caused by law enforcement increased significantly, with non-Hispanic Black males experiencing the highest mortality rates. Firearms were responsible for more than 87% of these deaths, highlighting persistent racial disparities in the US.
Scientists identified 81 previously unrecognized cancer-driving genes in basal-like breast cancer, a subset with poor outcomes. The discovery expands understanding of chromosomal rearrangements and opens possibilities for targeted therapy.
A new paper by MIT Professor Areg Danagoulian describes his idea for a satellite-based sensor system that can detect neutrons generated by high-energy protons colliding with radioactive material. The system could detect nuclear weapons with 99% accuracy, even in low-Earth orbit.
Researchers developed a method to analyze compounds pulled in cupping jars, detecting changes in 13 volatile compounds before and after treatment. These findings suggest that cupping therapy may have measurable physiological effects, which can be studied with modern analytical techniques.
A new strategy makes stem cell transplants safer by replacing chemotherapy-based treatment with targeted antibodies that recognize specific markers on blood-forming stem cells. This approach allows for less toxic treatment and could enable chemotherapy-free or chemotherapy-sparing transplantation approaches.
The Journalism Science Alliance has selected 25 new projects, receiving nearly €1 million in funding, to promote science-based investigative journalism worldwide. The projects, led by journalists and scientists from 24 countries, will benefit from expert mentoring, training, and networking opportunities.
Researchers from Penn, NYU, and the Linguistic Data Consortium create virtual patients with adjustable psychiatric symptoms to simulate real-world conversations. The STELLAR platform aims to augment clinician training practices with essential conversation scenarios.
The study demonstrated sustained improvements in disease features in mouse models with effects lasting throughout their lifespan. Genespire's approach has the potential to translate into human health as a single-administration treatment for patients with MMA.
The ORIGIN project aims to reduce development timelines for sustainable, fermentation-based ingredients from 5-7 years to 2-3 years. By combining AI, biotechnology, and fermentation, the project will address scientific and technological challenges to produce high-value natural ingredients.
A cohort study of nearly 20,000 NFL players revealed that players are dying of dementia and Parkinson’s disease at much higher rates than the general population. The study found a fourfold increase in neurodegenerative mortality among NFL players compared to the general population.
A survey of Illinois emergency departments found that many hospitals lack pediatric mental health specialists and struggle with timely access to evaluation by a mental health professional. The study proposes practical solutions, such as investing in mental health staffing, therapeutic activities, and real-time bed tracking to improve c...
Scientists have identified the genetics of caddisflies' evolutionary superpower, which involves a gene that produces a main protein in silk. The study found remarkable heterogeneity in those genes among individuals from two nearby wild populations, highlighting how nature modifies this bioadhesive material while preserving its performa...
A recent study published in Nature Communications has identified a clear link between the composition of gut bacteria and frailty in older women. The research found that lower gut bacterial diversity and impaired function are associated with increased vulnerability to disease, falls, functional impairment, and death.
Researchers developed a low-cost electrochemical sensor to detect dopamine levels in artificial human tears. The technology could support the development of new tools for monitoring Parkinson's disease and other conditions linked to atypical dopamine levels.
The Robotic Surgery Center at KU Ansan Hospital has introduced the Da Vinci 5 robotic system, expanding its precision surgical capabilities. With its advanced features and ergonomic design, the system is expected to enhance patient safety and clinical outcomes.
A first-of-its-kind randomized controlled trial demonstrates rapid metabolic improvements with a ketogenic diet compared to diet-as-usual, leading to correlations between ketone levels and reduced blood glucose and depression symptoms. The study also shows sustained metabolic improvements alongside significant reductions in schizophren...
Researchers found that hatchery-raised fall Chinook salmon exposed to noise were less likely to complete the journey to the ocean and back. However, when raised in a quiet environment, they were more likely to return than those raised with ambient or continuous white noise.
A Korean University research team has created a new brain implant that enables precise control of neural activity using temperature, opening possibilities for advanced brain–computer interfaces and treatments for neurological disorders.
A global analysis of childhood diets over nearly 30 years reveals that children worldwide consume low amounts of essential nutrients found in fruits, vegetables, nuts, and legumes. In contrast to many other countries, the US sees a decline in consumption of these foods from infancy to adolescence.
A new study finds that fully virtual applied behavior analysis (ABA) services delivered by a Board Certified Behavior Analyst (BCBA) are a feasible alternative to traditional in-person therapy. Children with autism who received focused ABA services showed improvements in adaptive skills, behavior outcomes, and family quality of life.
Researchers develop a comprehensive framework to predict drilling instability in backfilled ground, considering strength differences and asymmetry. The proposed design criterion aims to reduce inclined drilling deviations by at least 10 millimeters per meter of depth.
Glial cells play critical roles in determining brain recovery after TBI, and researchers have identified ways to selectively modulate their functions. The study highlights the importance of coordinated cellular behavior and suggests that targeting glial responses could lead to effective therapies.
A global analysis found alcohol use and smoking to be common risk factors for both breast cancer and atrial fibrillation/flutter in women ages 55 and older. High-risk zones were predominantly in Western countries with greater exposure to these lifestyle risks.
A study published in Nature Neuroscience reveals that the TDP-43 protein plays a crucial role in regulating microglial function. Microglia lacking this protein develop motor impairments and exhibit structural alterations in brain regions, highlighting its importance in preventing neurodegenerative diseases.
A new study reveals that racial and ethnic minority youth pay more attention to food influencers who share their racial identity, resulting in stronger engagement with unhealthy foods. The researchers found that identity-based social media marketing can be a powerful mechanism in shaping adolescents' eating behavior.
A study from Linköping University finds that mild COVID-19 can lead to long-term eye problems, including abnormal pupil function and strabismus, affecting daily life. Researchers developed a diagnostic model to detect these issues, which may lead to effective treatment.
A new study describes a gene therapy strategy that uses the brain's glymphatic transport system to distribute engineered viral vectors throughout the brain. This approach enables preferential targeting of human glial cells while minimizing exposure to other cell types and organs, addressing two major challenges in neurological medicine.
A Stanford-led study models how climate change and infrastructure investment can compound an affordability crisis, leading to near doubling of median water bills in cities like Santa Cruz. The research warns that even resilient cities may become vulnerable to water affordability issues over time.
Research on landfill-foraging white storks reveals a trade-off between food availability and increased risks from stress and DNA damage. Preliminary results show that young storks foraging on landfills have higher energy stores but also exhibit DNA damage at an early age.
Researchers found that KCL-286 enhances DNA repair and reduces neuronal inflammation in a mouse model of Alzheimer's disease. The drug activates the retinoic acid receptor-beta pathway, promoting the expression of certain repair genes.
A new study assesses how climate change affects predator-prey dynamics in a semi-arid ecosystem. Researchers found that during periods of low precipitation, owls shifted to different prey, increasing dietary overlap variability. Temperature was the strongest driver of these changes.
Researchers developed a human-safe drug that repairs DNA breaks and reduces inflammation in a mouse model of Alzheimer's disease. The approach targets multiple disease-relevant cellular pathways, providing a broader therapeutic strategy than previous approaches focused on individual disease hallmarks.
Scientists at King's College London have developed a human-safe drug that repairs DNA breaks and reduces inflammation in a mouse model of Alzheimer's disease. This approach targets multiple features of the disease simultaneously, providing a broader therapeutic strategy than previous approaches focused on individual disease hallmarks.
Researchers found that only 21.2% of service members and veterans who died by firearm suicide disclosed suicidal thoughts or plans before their death. Those who did confide in loved ones, rather than healthcare providers, making community-based suicide prevention strategies crucial for reaching those at risk.
A systematic review found that transmasculine people have pregnancy rates ranging from 6-9%, while postnatal depression rates are unknown. Testosterone use before pregnancy is associated with lower conception rates and higher miscarriage rates.
A study found that foreign direct investments raise employment by 13-16% in rural US counties, but have no significant impact on local incomes. However, higher wage growth and expanded housing supply are often observed in areas with increased FDI.
A new study suggests that California's wine industry is under threat from climate change and wildfires, particularly in established regions like Napa and Sonoma. However, areas like Mendocino and Monterey are expected to become increasingly favorable for premium vintages due to their projected increasing climatic suitability and decrea...
A new mathematical model shows that social norms significantly influence climate action, with strategies encouraging mitigation in one region potentially weakening it elsewhere. Regional actions can create unexpected ripple effects, highlighting the need for a nuanced approach to address climate change.
Researchers developed a technology that incorporates an elastic ion-conductive polymer into sulfide-based all-solid-state batteries to reduce cracking and interfacial degradation. The polymer buffer absorbs stress caused by electrode expansion and contraction, suppressing crack formation and improving cycle life.
Researchers propose a new standard, Human Fidelity, to measure the alignment of implantable brain devices with stakeholders' needs and expectations. The study identified five domains where gaps between devices and stakeholders exist, including Access and Uptake, Invasiveness, and Patient-Centered Outcomes.
Researchers found that taller trees have an advantage in younger forests due to increased light capture, but shade-tolerant species thrive under tall canopies in older forests. This study reveals a mechanistic explanation for forest succession and offers insights into climate modeling and forest management.