Researchers have found that combining pembrolizumab and lenvatinib shows promise in treating recurrent clear cell ovarian and endometrial cancers with poor responses to standard treatments. The LARA trial provides encouraging responses for patients with this rare and difficult-to-treat cancer subtype.
Researchers investigated the α7 nAChR-PARP1 axis as a therapeutic target for Parkinson's disease. The study found that activating α7 nAChRs suppresses PARP1 activity, reducing neurotoxicity and improving motor function in mouse models. This discovery provides a scientific foundation for developing novel therapies targeting this axis.
Researchers have developed a novel approach to fabricate high-performance nanophotonic devices with record-breaking ultra-deep nanohole waveguides. The technique enables the creation of nanostructures with extreme depth-to-diameter ratios, overcoming long-standing limitations in single-pulse nanolithography.
The review highlights key considerations for selecting an optimal drug target, including therapeutic hypothesis, druggability and safety, commercial tractability, and combination value. AI's capacity to process complex multimodal data enables researchers to navigate biological complexity and uncover disease-associated targets.
A novel nickel-based Pickering emulsion catalyst enables gram-scale synthesis of high-purity benzaldehyde with co-produced hydrogen, offering a sustainable alternative to traditional fine chemical synthesis. The synergistic effect of photon-heteroatom jointly promoted redox cycling accelerates the dehydrogenation reaction.
A new study reveals that nurse-delivered models of care can effectively manage common sleep problems like insomnia and OSA, but designing services with patients and staff is critical. The review found strong potential for GP nurses to deliver treatments like CBTi and support patients on CPAP machines.
Researchers developed a compact metasurface polarimeter for cancer tissue analysis, offering label-free imaging with reduced variability. The device's miniaturization opens the door to portable polarization-based confocal microscopy for routine histopathology screening.
A multi-institutional team has discovered a novel immune regulatory mechanism mediated by antibodies that selectively shut down overactive immune responses. The 'immune-induced TCR-like antibody' (iTab) can reduce disease severity and delay its onset in a mouse model of autoimmune disease.
Scientists have developed a novel catalyst that selectively repels chloride ions while accelerating oxygen evolution in alkaline seawater electrolysis. The optimized NiFe-LDH/Ce(OH)CO3 system delivers exceptional catalytic metrics and achieves energy efficiency of 68.59% at 500 mA cm-2.
Researchers at Saitama University discovered that mannanases, enzymes degrading glucomannan, are also essential for its synthesis in plants. The study found that Golgi-localized atypical mannanases play a crucial role in preventing aggregation of growing glucomannan chains.
A study from the University of Oregon found that heavy drinking takes a toll on college students' cognition, with impaired memory, attention, and decision-making. The research tracked participants over several weeks, revealing a link between alcohol consumption and cognitive lapses.
Researchers found that consumers are willing to pay more for glass wine bottles, with Gen Z willing to spend $35.38. Providing sustainability information about packaging can influence willingness to pay, with a significant discount relative to glass packaging.
A machine learning approach improves how roaring behaviour can be studied by detecting long-distance roaring based solely on acceleration data. The algorithm works reliably with both male and female lions, even with mixed signals when walking while roaring.
A new Northern White Rhino embryo has been successfully produced, boosting hopes for the species' survival. The BioRescue Consortium's work has also underscored the importance of public engagement, communication, and ethical reflection in wildlife conservation.
A Swedish study found that children adopted into families with better home environments showed improved adult psychosocial outcomes, including lower criminal convictions and higher educational achievements. The benefits also extended into the next generation, with offspring displaying modestly higher psychosocial functioning.
The consortium aims to forge actionable drug development solutions for patients living with AATD by collaborating on endpoints, biomarkers, and clinical trial design. AIRNA brings RNA editing expertise to the consortium's efforts to accelerate drug development for alpha-1 antitrypsin deficiency.
In England, 13,386 patients waited at least three days for A&E treatment in 2025, with numbers spending a whole day in emergency departments increasing by a third since 2023. The prolonged waits are causing harm to patients nationwide, with some saying they'd rather die at home.
A Swedish study of siblings found that adopted children who grew up in more favourable family environments had lower risks of mental health issues, criminality, and social problems. These benefits extended to the next generation, with adopted children's offspring displaying higher functioning and lower risks.
A new study analyzing nearly 100 travellers' diaries reveals that turnpiking improved road conditions, reducing danger and speeding up journeys. The toll-funded system made a major contribution to the Industrial Revolution by reducing freight rates and enabling faster stagecoach travel.
Doctors should exercise caution when commenting on public figures' mental health, as diagnoses require direct assessment. The BMJ opinion article explores ethical tensions and the importance of professional standards in such cases.
The new fiber probe can track three key biomarkers - glucose, lactate, and ethanol - simultaneously, providing a more complete picture of metabolic health. This innovation offers faster, real-time sensing technologies for clinicians to respond rapidly to evolving metabolic crises.
A new UBC study maps climate change's impact on Canada's environment, revealing regions with high unpredictability and lower biodiversity. The team identified over 2.7 million square kilometres of unprotected land that could strengthen the country's conservation network.
Scientists found that specific genetic sequences, known as HAQERs, have a significant impact on human language abilities. These regions evolved before humans and Neanderthals diverged and are thought to be responsible for the development of modern human language.
A new $15 million research network will investigate the causes and treatments of heart valve disease, which affects over 80 million people worldwide. The American Heart Association hopes to develop early warning signs and diagnosis methods to expand treatment options and improve quality of life for patients.
Research from the University of Texas at Austin finds that consumers pay up to $170 extra per vehicle when buying a used car with nearly identical mileage but one digit off, due to left-digit bias. This phenomenon can result in higher prices for cars just below round numbers like 20,000 or 50,000.
Paxlovid helps vaccinated adults recover faster from COVID-19, but does not reduce hospital admissions or deaths. The drug significantly reduces viral load and side effects, making it a valuable treatment option for higher-risk patients.
Penn State professor Greg Fosco emphasizes the importance of parental monitoring, autonomy-supportive parenting, and fostering a sense of purpose in teenagers' lives. Research suggests that when adolescents perceive a stable relationship with their parents, their well-being suffers, while having a sense of purpose is linked to lower su...
A study from the University of São Paulo reveals that neurodegenerative processes extend beyond the central nervous system, affecting various targets throughout the body. The researchers identified over 9,000 autoantibodies linked to immune status, neurological damage, and symptoms specific to each disease.
A new model predicts that the selection of a single follicle for maturation during human pregnancy is entirely random, contrary to prior theories. The model suggests that once one follicle is selected, estradiol levels start rising, causing FSH levels to fall below the threshold, and unselected follicles die off.
A team of researchers has developed a new microbial method for producing medium-chain fatty acids, which are used in various industries, including cosmetics and detergents. The breakthrough enables the use of waste materials as feedstock for fermentation, reducing reliance on palm oil.
A global trial involving 1,670 patients with intracerebral haemorrhage found that treatment with a single pill combination of three low-dose blood pressure medicines reduced the risk of another stroke by 39%. The study showed significant benefits in reducing major cardiovascular events and improving blood pressure control.
Researchers developed liquid biochar mineral complex fertilizers that significantly increase crop yields and improve nutrient efficiency. The nitrogen-enriched formulation delivered the strongest results, achieving positive nitrogen and phosphorus balances while reducing labor and cost.
Researchers found that connected habitats enhance the ability of amphibian skin microbiome to defend against diseases by increasing beneficial bacteria presence. This study highlights a critical link between environmental disturbance, microbial defenses, and disease dynamics.
The SNMMI 2026 Annual Meeting will showcase the latest scientific developments driving advances in nuclear medicine, including earlier diagnosis, personalized treatment, and improved disease management for various conditions. The meeting will feature over 150 scientific sessions, satellite symposia, and a cutting-edge exhibit hall.
A new study from Weill Cornell Medicine found that the protein caspase-5 boosts cell growth in the gut lining by amplifying Wnt signaling. This balance is crucial for maintaining a healthy intestinal lining, replacing injured cells with new ones, and preventing diseases like colorectal cancer and inflammatory bowel disease.
Scientists at St. Jude Children's Research Hospital identified a key regulatory enhancer, ecMYC E1, that drives MYC expression in pediatric medulloblastoma, a type of brain cancer with poor outcomes. Silencing this enhancer reduces MYC transcription and can be targeted to treat the disease.
A recent study published in Neurology found that people with epilepsy who experience poor sleep are at a higher risk of developing dementia compared to those without epilepsy. Optimal sleep, defined as six to eight hours per day, is associated with better cognitive function and lower dementia risk.
Researchers found that modern AI language models can distinguish between categories like commonplace, improbable and impossible events with high accuracy. The models' internal patterns, or vectors, show a correlation with human uncertainty about statement plausibility.
MSK researchers showcased innovative therapeutic advances for HER2-driven rectal and KRAS-driven pancreatic cancers, as well as a promising mRNA vaccine. CAR T cell therapies targeting uPAR showed promise in shrinking solid tumors and overcoming treatment resistance.
A study by Yokohama National University finds that work ability, inclusion, and human resource development are crucial elements for promoting disability inclusion in the workplace. The research suggests a framework to reduce barriers and promote continued success among disabled individuals.
A new study by the American Academy of Neurology found that virtual and in-person visits for new neurology patients have no significant difference in follow-up clinic visits or emergency department hospitalizations. However, some conditions like Parkinson's disease and multiple sclerosis showed a higher need for follow-up evaluations a...
The American Ornithological Society has awarded grants to six early-career researchers from Latin America and the Caribbean to study bird conservation in the region. The projects focus on endemic species and will contribute to broader efforts across the region, strengthening conservation capacity.
The Columbia University Fertility Center has been ranked #1 on Newsweek's list of America's Best Fertility Clinics for the second consecutive year. The center offers cutting-edge innovations such as HELIOS near-infrared light technology to enhance embryo development, and STAR AI-assisted method to retrieve sperm in men with azoospermia.
A recent study found that nearly 69% of former professional football players may have sleep apnea, with many cases going undiagnosed. Untreated sleep apnea is linked to worse mental, cognitive, and physical health outcomes among former athletes.
Researchers developed an electrochemical sensor to detect pancreatic cancer at low concentrations, improving accessibility and effectiveness of treatment. The device identifies CA19-9 protein, a key biomarker for the disease, allowing for early diagnosis and potentially increasing survival rates.
Researchers create model connecting nuclide signal fluctuations to progressive changes in rock structure leading to critical failure. This allows for early warning of geohazards such as landslides and avalanches.
A new NYU study analyzes hourly ridership at 10 major NYC subway stations between 2023 and 2025. Heavy rain affects peak hour travel, while extreme cold has a smaller impact, especially off-peak. The research highlights the importance of considering infrastructure, station design, and surrounding land use in transit planning.
A Princeton-led study examines the complexities of translating natural resource wealth into economic prosperity. Higher social and human capital, as well as institutional safeguards, are critical in avoiding the 'resource curse,' a phenomenon where extraction leads to limited growth and unstable institutions.
A rare case of mucinous ovarian carcinoma was reported in a postmenopausal woman, initially misdiagnosed as a pelvic abscess due to nonspecific symptoms and radiologic features. The diagnosis was confirmed after advanced imaging and tumor marker assessment. Early recognition is crucial for timely diagnosis and effective treatment of th...
The study examines the cumulative physical, cognitive and psychological demands of a Formula 1 season on team personnel. Researchers aim to develop targeted interventions to support performance, recovery and well-being in one of the world's most demanding team environments.
Researchers found that an ASO strategy boosts expression of the closely related HNRNPH1 protein, reducing symptoms of HNRNPH2-related neurodevelopmental disorder. The study provides vital mechanistic data to support advancement of this promising therapy.
A study at University at Buffalo found that L-arginine enhances protein droplet stability, preventing fibril conversion and preserving microtubule assembly. This naturally occurring small molecule may help guide therapies targeting fibril formation in Alzheimer's disease.
Research by Virginia Tech researcher Phil Thompson and his colleagues found that when managers frame work problems as potential losses, employees are more likely to take action. Framing something as a loss yields employees to voice a work suggestion more than framing them as gains. This approach can influence employees' motivation to s...
The Yolo County basic income program provided a monthly stipend of $1,289 per month to 76 mostly single-parent families, helping them gain housing, food, and general wellbeing. Participants reported reduced stress levels and improved parenting skills, but faced challenges in achieving long-term financial stability.
A new PET biomarker outperforms established risk scores in predicting survival for large B-cell lymphoma patients. Metabolic tumor volume, derived from PET imaging, was found to be an important predictor of progression-free survival.
A USF study found that easy-to-use QR codes significantly reduce frustration and cognitive load among older adults, leading to higher satisfaction and customer loyalty. The research emphasizes the importance of businesses incorporating user-friendly technologies to cater to seniors' needs.
A recent study investigated microplastic movement in freshwater ecosystems across Pennsylvania, finding that watersheds with higher population densities and adjacent wastewater treatment plants had higher concentrations of microplastics. The research also revealed local features, such as forests and rural areas, play a critical role in...
Researchers will build connections with Detroit's digital equity ecosystem and promote digital inclusion to link cancer patients, survivors, and caregivers with resources. The Digital Engagement and Cancer Outcomes (DECO) Center aims to advance interventions that improve outcomes at the individual level.
Climate change is already reshaping health, work, and food security in Europe, with rising temperatures reducing working hours and economic output. Climate extremes are increasing food insecurity primarily through higher prices and diet quality, according to Shouro Dasgupta, a leading expert on the economic impacts of climate change.
The experimental drug DH20931 targets triple-negative breast cancer by triggering a surge in fat-like molecules called ceramides, overwhelming cancer cells with toxic fats. In lab experiments, the drug made standard chemotherapy more effective, reducing the dose needed to kill cancer cells by about fivefold.
Researchers found that electron spin interacts differently with mirror-image molecules, causing small but meaningful differences in behavior during dynamic processes. This asymmetry could lead to the dominance of a single 'hand' in biology, offering a possible route toward understanding how one molecular form came to dominate.
The study found that Methana volcano's magma chambers held steady amounts of magma for over 100,000 years, with intense activity peaking during zircon growth. This challenges the assumption that a prolonged period of volcanic silence means a volcano is extinct.
A study by University of Innsbruck researchers found that removing secondary product displays in crowded supermarket aisles increases sales by 11.5% due to increased browsing and interactions. Shopping carts amplify the negative effects, making narrow aisles feel tighter and reducing perceived control.
A new scoping review reveals silicone toothbrushes as a promising tool in global oral health, yet their effectiveness and environmental impact remain understudied. The study suggests that switching to silicone toothbrushes could be a viable alternative to traditional toothbrushes.
tACS modulates brain oscillations, induces synaptic plasticity, and regulates neurotransmitter release to alleviate symptoms of various neuropsychiatric conditions. Personalized approaches are essential for treatment efficacy.
A new study found that in-aisle displays can increase spatial crowding, leading to reduced sales and purchase-related behaviors. For cart users, this effect is stronger, with increased crowding and reduced control while shopping.
A study found that higher midlife cardiorespiratory fitness is strongly associated with later onset of chronic disease, lower overall disease burden, and longer life expectancy. Adults with higher fitness levels developed fewer chronic diseases and spent more years free from serious illness.
Researchers have shown that extracts from bioengineered chewing gum reduce levels of three microbes linked to worse outcomes in oral cancers, including HPV and bacteria Pg and Fn. The findings support the value of advancing these therapies to clinical trials as adjuvants or prophylaxis.
Researchers found that malaria significantly influenced habitat choice, pushing groups away from high-risk environments and separating populations. This led to the fragmentation of human societies, shaping their population structure for the past 74,000 years.
Researchers aim to accelerate public spinach breeding by identifying genetic variation and developing genomic tools for Pythium tolerance. They are evaluating 480 diverse spinach genotypes to identify over 30 Pythium-tolerant lines.
Researchers analyzed 505 ME/CFS memorial records, highlighting common themes of neglect, dismissal, and misdiagnosis. The study suggests that ME/CFS patients face widespread systemic, clinical, and social challenges, which contribute to their early deaths.
A Chinese-German research team has reconstructed the genetic processes of re-diploidization in snow carps, revealing the fusion of chromosomes as the first stage. This process, which occurred relatively recently in evolutionary terms, led to an initial fourfold set of chromosomes that eventually reduced to two through asynchronous fusi...
Researchers analyzed a Virginia colony of wild gray bats, finding they modify their echolocation calls based on the size of their flying group and environmental obstacles. The study reveals how these adjustments help the bats navigate safely during flight.
A new study finds that blood protein levels change markedly over the course of a lifetime, rendering adult reference values inadequate for children and adolescents. Gender differences also emerge, particularly after puberty.
Internationally recognized pediatric hand surgeon Dr. Scott H. Kozin takes the helm as Shriners Children's Chief Medical Officer, bringing decades of clinical expertise to expand access to high-quality pediatric care nationwide. The appointment comes at a pivotal moment, with the upcoming opening of the new Shriners Children's Research...
A recent study found that 98% of environmental claims made by the world's largest meat and dairy companies can be classified as greenwashing. The analysis of over 1,200 claims from 33 major companies revealed a lack of evidence supporting many promises.
A recent study published in PLOS Global Public Health found that practicing yoga can significantly decrease blood pressure in individuals with overweight or obesity. The meta-analysis of 30 studies showed that systolic and diastolic blood pressure were lowered by an average of 4.35 mmHg and 2.06 mmHg, respectively.
Researchers found at least 94 elections and referendums across 52 countries were disrupted by natural hazards between 2006 and 2025. The report highlights the importance of election timing, coordination with meteorological agencies, and preparedness measures to safeguard democratic processes under increasing environmental pressure.
A new atlas reveals significant overlaps between Arctic oil and gas development and Indigenous Peoples' Lands, ecologically sensitive areas, and key Arctic species. The study highlights potential ecological disruption and social tension in heavily-exploited regions.
A recent study by Chinese researchers has quantified lake carbon dioxide emissions in China, finding a significant increase of 24% over the past two decades. The study highlights the importance of high-resolution monitoring to refine lake carbon budgets and inform effective climate mitigation policies.
Researchers at Baylor College of Medicine developed new methods to study DNA management in bacteria, revealing that DNA shape and flexibility play critical roles in gyrase activity. The study identifies specific DNA sequences that guide gyrase binding and interaction with the enzyme.
A study of 113 baby barn swallows in Colorado found that temperature extremes and variability negatively impact the youngest, smallest, and most neglected nestlings. The research suggests that developmental constraints play a crucial role in determining the effects of temperature on nestling growth.
A new study from the University of Toronto links childhood sexual abuse to a significantly higher likelihood of cancer later in life. Researchers found that those who experienced childhood sexual abuse had about twice the odds of reporting a cancer diagnosis compared to the general population.
A new study highlights the gap between India's hazardous waste production and registered contaminated sites, emphasizing the need for coordinated monitoring and robust remediation processes. The researchers propose a Contaminated Site Monitoring, Assessment, and Remediation (CS-MAR) framework to improve governance of contaminated sites.
Researchers investigate Cu/ZnO/Al2O3 nanoparticles using operando TEM, revealing dynamic structural changes during methanol synthesis. A 'frustrated phase transition' is identified, where the catalyst constantly transforms between states, driving its high activity and stability.
A study by University of California, Davis found that California's conifer forests have lost between 6% and 11% of their area over the past three decades due to wildfires. Reforestation efforts are not keeping pace with the losses, with only about 1% of deforested Forest Service lands being replanted between 2016 and 2023.
A new method developed at LMU reconstructs precise energy spectra without lengthy calculations, revealing previously hidden details. This approach uses complex time evolutions to supplement time-dependent data and effectively overcomes the resolution limit, allowing finer structures to be resolved.
Scientists at Arizona State University have isolated and studied proteins essential for tularemia's infection process, revealing a potential vulnerability that could lead to new treatments. The research advances understanding of the bacterium's biology and paves the way for developing targeted therapeutic strategies.
Dr. Gang Hu's research focuses on the complex interplay between lifestyle factors, biomarkers and genetic influences in chronic disease development. He has made significant contributions to understanding gestational diabetes mellitus and its long-term health effects.
PhysMAP is a machine learning algorithm that separates individual cell type signals within electrical noise, enabling the study of how cell types shape healthy computations and pathological states. The tool has been trained on seven open datasets and can be applied to new datasets without requiring additional experiments.
Breast cancer cells that spread to the brain rely on a specific metabolic pathway to survive. Targeting this pathway with ACSS2 inhibitors can induce ferroptosis and shrink tumors in preclinical models.
New research found that bird species with a skewed sex ratio are primarily caused by demographic factors, not the other way around. The study of 261 bird species revealed that one sex is more likely to die before reproducing due to differences in survival rates.
Researchers from Institute of Science Tokyo developed a 5.8 GHz foldable antenna designed to provide high antenna gain while remaining compact enough for small satellites. The system aims to improve communication capabilities of small satellites used in applications such as space-based internet services and disaster monitoring.
Researchers have overcome epigenetic silencing to create genetically engineered chickens that can hatch with useful medical proteins. This breakthrough could lead to the development of stable lines of birds that lay eggs containing beneficial proteins.
A Mayo Clinic study provides preclinical evidence for a targeted approach to managing immune-related kidney inflammation triggered by immunotherapy. The findings suggest that TNF-alpha blockade may improve markers of kidney injury and could be explored as a preventive measure.
Researchers have made a groundbreaking finding on the underlying biological mechanisms of an innovative surgical approach to deliberately 'train' the heart. By applying pressure overload in the early neonatal heart, scientists triggered regenerative mechanisms that increase the number of heart muscle and vascular cells.
A new role for reproductive hormone secretoneurin has been discovered, showing it stimulates the growth and activity of neurons controlling reproduction through a previously unknown delivery mechanism: exosomes. This finding may shed light on the causes of reproductive disorders such as hypogonadotropic hypogonadism and Kallmann syndrome.
A pioneering study at the University of Bristol found that dairy calves fed less complete tasks faster and remember more when pursuing milk, but miss out on play. In contrast, calves fed more were more inclined to play. The study suggests that feeding calves more can suppress hunger and promote other important behaviors like play.
Researchers developed pigs with knocked-down SLA-I/II molecules, showing reduced human complement-dependent cytotoxicity and stronger resistance to T-cell responses. The findings suggest a multi-pronged approach combining genetic modification and targeted immunosuppression for successful pig-to-human transplantation.
New research suggests chalk-stream salmon be classified as a sub-species of Atlantic salmon, with potential benefits for targeted conservation. The study found genetic distinctness between chalk streams and nearby rivers, highlighting the importance of protecting these habitats.
A new study found that microbial proteins make up to 11% of the total protein content in fermented foods and comprise 60% of identified proteins. These microbes convert raw substrates into nutritious products, influencing gut physiology and potentially impacting health outcomes.
Researchers found that disruption of communication between cancer-causing cells and surrounding healthy tissue can prevent tumor growth. The study suggests that early intervention may be possible, as the transformed environment is reversible if caught early enough.
Researchers have overturned decades-long assumptions about why HBV fails to infect mouse liver cells, pointing towards a new disease model. The study suggests that the problem lies in a late step during the viral entry process, which could be disrupted by certain mechanisms.
Researchers have developed a complementary perception strategy combining visual localization with tactile mapping for robots to locate and read object surface features. The system uses a single RGB-Depth camera and soft pressure sensor array to identify object position, size, and geometry through vision and tactile scanning, respectively.
Researchers found a 100-million-year-old forest ecosystem's diversity in Kachin region amber. The fossil, a true water bug with striking chelae, is the fourth known case of these structures evolving independently.
The MEDABIS-PRO project aims to elucidate the effects of magnetic fields on dose delivery and biological radiation in MRI-guided proton therapy. Researchers will analyze the impact of magnetic field orientations and strengths on proton beam propagation and biological effects, using computer simulations and measurements.
A study reveals SYNGAP1 encephalopathy's complex link between genotype and phenotype, expanding its genetic basis. The research identifies four novel variants and shows that the gene's severity depends on other genetic factors, not just the specific mutation.
New research suggests that geoengineering can increase land carbon storage in the Amazon, potentially protecting it from climate change. The study finds that stratospheric aerosol injection reduces warming and increases vegetation productivity, resulting in a 10.8% increase in land carbon storage.
A global paradigm shift is needed to protect intact ecosystems and prioritize Nature Positive framework, integrating Indigenous knowledge and finance. The webinar series on May 28, 2026, will explore effective actions for people and nature, guided by the Three Conditions Framework.
Scientists have developed a new material that dramatically improves the efficiency of producing clean hydrogen fuel from water using sunlight. The innovative system, which anchors platinum clusters onto a specially designed organic framework, accelerates the chemical reaction 109 times faster than before.
Researchers have developed a new approach to unlocking hydrogen from magnesium hydride using catalysts, which can reshape the release process and make it more efficient. This breakthrough has significant implications for the development of hydrogen-based energy systems and could support their broader adoption.
Researchers at MIT have discovered a mathematical connection between quantum mechanics and classical physics, enabling the description of quantum behavior using everyday classical ideas. The team's findings shed light on phenomena such as the double-slit experiment, which has long been challenging to explain using classical tools.
A HKUST team has developed an innovative laser control technique called Active Pixel Power Control (APPC) to reduce crosstalk in all-optical neural interrogation. APPC successfully preserved signal quality of neuronal signals while suppressing optogenetic artifacts and reducing the issue of crosstalk in larval zebrafish brain studies.
Quaise Energy is building the world's first power plant using superhot geothermal energy, with the goal of producing at least 50 megawatts of clean electricity. The project aims to harness temperatures greater than 300 degrees C and validate its long-held hypothesis that higher subsurface temperatures can improve power production.
Scientists at KTH Royal Institute of Technology have discovered a new way to fight potato late blight, a plant disease that once triggered the Irish Potato Famine. The peptide CS5 specifically attacks Phytophthora infestans without harming other plants.
Two new studies from Aarhus University reveal that endometriosis is often difficult to recognize in its early stages, requiring a systematic approach even when symptoms are diffuse. The studies highlight the need for improved knowledge, collaboration with specialists, and referral pathways to reduce diagnostic delays.
A comprehensive study reveals that high sodium intake, low fruit consumption, and lack of whole grains are the primary drivers behind 5.9 million cardiovascular deaths worldwide. Researchers emphasize the need for targeted policy interventions, such as mandatory front-of-pack labeling and food reformulation in high-population countries.
Researchers analyzed battery development in electric vehicles over 15 years, finding that market innovation can quickly address material shortages and price increases. The study suggests individual materials may not be as critical to the energy transition as previously thought.
Researchers map the full phase evolution of IV-VI TMDs, achieving scalable fabrication of atomically thin sheets for flexible thermoelectric devices. Novel phase transition modes are discovered, providing a precise basis for phase regulation and enabling mass production of high-performance materials.
The GREEN TALENT project organized four DemoHub workshops in Malta, Greece, Cyprus, and Bulgaria to foster collaboration, innovation, and hands-on learning. The workshops focused on addressing climate and biodiversity challenges, engaging island communities, policymakers, and experts.
Researchers have achieved a record-breaking transition temperature of 63 K in ambient-pressure nickelate films, surpassing previous limits. This breakthrough utilizes the 'Gigantic-oxidative Atomic-layer-by-layer Epitaxy' method and showcases enhanced Meissner effect and zero-resistance temperatures.
Researchers discovered that sweat bees can temporarily alter their shimmering hues in response to changing humidity levels. The study found that moisture causes the bees' microscopic structures to reflect different wavelengths of light, resulting in colour changes from deep blue to copper-green and back again.
Twelve climate researchers present a policy brief calling for the phasing out of fossil fuels, citing international law and economic feasibility. The policy package offers six integrated solutions to facilitate a controlled transition, addressing key obstacles such as production, taxation, and labor protection.
Researchers at the University of Cape Town have identified a critical molecular switch that drives the formation of cancer-associated antigens. By understanding how enzymes relocate within a cell, they have uncovered key mechanisms for tumorigenesis.
Professor Shirley Meng will lead NTU's industry engagement efforts, forging partnerships with global companies and establishing joint research institutes worldwide. She brings expertise in integrated battery performance, safety, and sustainability, driving interdisciplinary collaborations and championing fundamental sciences for real-w...
Researchers discovered that small lesions in white matter can trigger a response in connected grey matter, leading to neuronal activity fall, microglia activation, and synapse loss. However, this response is part of the repair process, essential for brain regeneration.
A new study in Nature has filled in the gaps of how a widely used antifungal drug works, revealing its surprising mechanism and providing critical insights for designing next-generation therapies. The research found that caspofungin binds to a growing chain of cell-wall material produced by an enzyme, effectively stalling its activity.
A study found that physicians' workload increases in early pregnancy, with surgeons returning to work sooner after childbirth. The study suggests that stronger workplace supports can improve physician well-being and retention.
A cross-sectional study found a substantial increase in medication use for opioid use disorder among Medicaid beneficiaries, potentially contributing to reductions in overdose deaths. The study suggests that expanding access to medications for opioid use disorder may be an effective strategy to address the opioid crisis.
Computer scientist Micheal Lones warns that using generative AI in machine learning increases the risk of malicious cyberattacks, data leaks, and bias against underrepresented groups. He advises developers to manually evaluate LLM-generated code and outputs to mitigate these risks.
A new study suggests that a digital platform called Living Memory Home for Dementia Care Pairs (LMH-4-DCP) can help reduce grief severity and improve relationships between caregivers and individuals with dementia. The platform facilitates reminiscing and shared memories, promoting dignity and respect for care recipients.
A new international study shows that gene therapy targeting the OTOF gene successfully restored hearing in most participants, with significant improvements in speech perception and language skills. The treatment remained safe and effective for up to 2.5 years, offering new hope for individuals with inherited deafness.
The study identified over a million genetic variants, revealing unique diversity and adaptations to environments. Ancient DNA and geographic data also provide insights into the movements and migrations of Native American populations.
A team of physicists has discovered a way to boost the intensity of high-power laser light, opening up new possibilities for experiments in quantum electrodynamics. The breakthrough uses an unusual process to create extremely bright ultraviolet light, which can be focused into a tiny point creating immense energy concentration.
Immune checkpoint inhibitors can cause immune-related hepatotoxicity, which is associated with female sex, younger age, Asian ethnicity, chronic liver disease, specific cancers, dual ICI therapy, and concurrent hepatotoxic drugs. Promising biomarkers include blood cell counts, CRP, autoantibodies, cytokines, SNPs, HLA types, and gut mi...
Researchers at Rockefeller University have captured the first snapshot of a mechanical signaling complex in action, revealing that compression is the key to transmitting mechanical information. The study has implications for cancer and other diseases, and could lead to new treatments.
Researchers identify a new coronavirus, CcCoV-KY43, that can enter human cells through the CEACAM6 receptor. The study used genetic sequences and synthesized spike proteins to screen for binding to human receptors, revealing the versatility of alphacoronaviruses in entering human cells.
A web tool called Living Memory Home for Dementia Care Pairs facilitates collaborative reminiscence therapy, reducing feelings of pre-death grief and improving relationship quality. The app promotes well-being and connection between dementia patients and caregivers, leading to better care outcomes.
A Kobe University study reveals a neuronal connection between the motor cortex and insular cortex that regulates tics in Tourette's syndrome. The discovery suggests a new pathway for treating the condition, potentially involving non-invasive therapies like ultrasound neuromodulation.
Researchers found no evidence of persistent SARS-CoV-2 in placentas collected from women who recovered from COVID-19. However, structural and inflammatory changes were observed in some placentas, suggesting the immune response may outlast the virus.
A new study found that patients experiencing socioeconomic marginalization are more likely to seek initial concussion care in hospital emergency departments, leading to lower follow-up rates. Patients without family physicians were up to 70% less likely to follow up.
A new study reveals that astrocytes build far-reaching connections to communicate with other cells across the brain. These pathways appear to connect distant regions in ways that had not been mapped before, adding a new layer to how brain regions stay connected.
The study found significant reductions in suicide mortality among adolescents and young adults after the US launched its 988 Suicide and Crisis Lifeline. Larger reductions were observed in states with the highest adoption of the 988 Lifeline services.
Researchers at Penn State have made precise calculations, showing that a discrepancy in particle physics was a fluke, not nature. The study strengthens confidence in the Standard Model to 11 decimal places, ruling out new forces or quantum objects.
An international team of physicists has achieved a breakthrough in understanding the muon's magnetic moment, resolving a decades-long discrepancy between theory and experiment. The study delivers the most precise calculation to date of a key component underpinning the muon's magnetism, agreeing with experimental measurements within jus...
A recent study by AI researcher Oskar van der Wal found that language models like ChatGPT can absorb biases around gender and ethnicity, which are then embedded in the model. To detect and remove these biases, new measurements are needed.
Researchers develop a breakthrough molecular design strategy to push PTAA-based PSCs beyond 26% efficiency by addressing carrier transport challenges at 2D/3D heterojunctions. The design enhances hole extraction through π-conjugation extension of triphenylamine-based semiconducting ligands.
Researchers developed a method that improves perovskite solar cell performance by triggering molecular interactions at the interface between two films, resulting in more efficient and durable material. The technique achieved a power conversion efficiency of 25.61%, surpassing previous records.
A study reveals that older adults receiving government-funded home care struggle to access the support they need, often feeling overwhelmed by complex systems and limited budgets. The research highlights a significant gap in the program's capacity to provide person-centered care, particularly in areas like nutrition.
Australian scientists have developed an injectable therapy called Snoretox-1 to help clear blocked airways in flat-faced dogs suffering from brachycephalic obstructive airway syndrome (BOAS). The treatment shows early success in improving breathing difficulties in bulldogs.
Researchers found distinct gut microbiome characteristics that predicted treatment response to the low FODMAP diet and rifaximin. Patients who responded to these treatments had different microbial signatures, with increases in diversity for those on the low FODMAP diet and resilience against antibiotics for those on rifaximin.
Researchers identified previously undescribed triggers of rare broadly neutralizing antibodies in people living with HIV. The study found that interactions between the immune system and other infections may be linked to how the body responds to HIV.
This review evaluates point-of-care (POC) biosensing strategies for ultra-early mTBI triage, focusing on platforms, matrix effects, and benchmarking aligned with CT-based decision-making. Key findings include the critical vulnerability of hemolysis elevating UCH-L1, and the importance of anchor development to the ED CT-triage use case.
Researchers at Tohoku University developed a strong, biodegradable material made from bamboo sheets and PHBH, which can be used to estimate biodegradation in seawater. The material's strength is linked to its degradation rate, providing a predictable usable lifetime for sustainable materials.
A USC-led team is working on a medical device that uses tears to monitor health, starting with dry eye disease. The device aims to provide continuous monitoring and automated medication delivery, improving patient comfort and treatment efficacy.
Carl Solder, Chief Technology Officer of Cisco Australia and New Zealand, brings 40 years of expertise to Curtin to mentor students, deliver seminars, and share insights on networking technologies. He aims to help students navigate the rapidly evolving global technology landscape.
The study aims to implement skills-based mental health and substance use training for community health workers, embedded with peer recovery coaches. Over 5000 patients will be followed to measure the approach's effectiveness in re-engaging patients with care.
Recent studies have explored tumor vaccine platforms, including peptide, dendritic cell, and nucleic acid-based vaccines. Personalized neoantigen vaccines are refining precision in HCC treatment, but challenges persist due to immunosuppressive tumor microenvironments and heterogeneity.
Aging bone repair declines due to mitochondrial DNA structures disrupting stem cell function, reducing energy production and causing cellular senescence pathways. Targeting these structures may restore balance between bone and cartilage formation during healing.
Despite clear guidelines, fewer than half of privately insured pregnant women with opioid use disorder receive the standard treatment of medication for opioid use disorder (MOUD). Early identification and timely intervention are crucial in addressing this public health issue.
A study of Finnish special needs and special class teachers found that data processing, statistics, and probability are under-taught areas, mirroring trends in the US. The researchers emphasize the need for stronger teacher preparation, ongoing professional development, and support to ensure effective strategies are used consistently.
A study of 65 brews found that many conventional and nonalcoholic beers provide substantial levels of vitamin B6. Nonalcoholic beers have higher vitamin B6 levels than those made using yeast that produces less ethanol.
A recent study estimates that 2.8% of US residents over 12 used psilocybin in the past year, highlighting the need for clinicians to be aware of its use among patients with depression. The findings also underscore the importance of longitudinal studies and increased public health surveillance as de-criminalization efforts progress.
Researchers analyzed bone collagen peptides from avian remains found at the Gungok-ri site in South Korea, identifying the presence of chickens and their management during the Proto-Three Kingdoms period. The study's findings provide insights into Korean food culture, agriculture, and animal domestication.
A phase 2 study led by NYU Langone Health showed that adding pembrolizumab to standard chemotherapy and radiation with surgery allowed 60% of patients to avoid bladder removal for up to two years post-treatment. This breakthrough treatment offers hope to patients with muscle-invasive urothelial cancer of the bladder.
Researchers have developed a new metagenomic software called nanoMDBG, which enables faster and more accurate analysis of microbial diversity. The software can assemble microbial genomes from nanopore sequencing data, allowing for the tracking of complex microbial communities over time.
A new study found that breast milk helps maintain a balance of beneficial bacteria in babies' developing gut microbiomes, including E. coli and Bifidobacterium. This mutualistic relationship supports healthy infant development and may have implications for future synbiotics.
Researchers at the Max Planck Institute for Solar System Research investigated how solar prominences form and what secrets their longevity holds. They found that multiple processes create a balance between material loss and supply, driven by magnetic fields and temperature gradients in the Sun's atmosphere.
A CDC study found that approximately half a million post-9/11 U.S. veterans had high blood pressure, highlighting the need for early prevention strategies. The study also revealed that Black veterans were more likely to have high blood pressure and women were often undiagnosed.
Researchers have developed a new molecular imaging technology that illuminates proteins inside living cells and animals far more clearly than before. The system uses engineered fluorescent nanobodies to reduce background noise by as much as 100-fold, enabling sharper visualization of protein location and dynamics.
MIT researchers found plants respond to sound waves generated by raindrops, stimulating germination. Seeds exposed to rain sounds germinated 30-40% faster than those not exposed.
Salk scientists and collaborators advance visualization technology using visible-spectrum antigen-stabilizable fluorescent nanobodies (VIS-Fbs), reducing background fluorescence by up to a hundredfold. The new probe enables high spatial and temporal precision, allowing for real-time tracking of dynamic changes in living models.
A newly discovered pitviper, Trimeresurus lii, is found to be a distinct lineage with unique physical characteristics and venomous properties. The species was previously mistaken for the bamboo pitviper due to similar green appearance.
A study published in npj Aging found a novel region of DNA and two associated genes connected to frailty, offering new avenues for early detection and targeted intervention. The discovery provides biological insights into the condition and points toward personalized approaches to supporting healthy aging.
In a unique behavior, monkeys on Gibraltar have learned to eat dirt to help them digest the junk food consumed by tourists, which disrupts their gut microbiome. The researchers found that geophagy is socially learned and has become part of the macaques' culture, with different troops having preferences for certain types of soil.
Researchers found massive amounts of ammonia gas expected but less than anticipated, and instead discovered thick patchy water-ice clouds on the exoplanet. The discovery sheds light on the limits of current models for studying exoplanet atmospheres.
A study found that HAART led to a resurgence of syphilis in the US, with increases concentrated among men. The availability of HIV treatments improved survival but also changed sexual behavior and public health effects.
A new book calls for urgent action to address digital accessibility gaps, which harm over 1 billion disabled people worldwide. The Digital Accessibility Ethics Framework aims to guide governments and organizations in creating inclusive digital environments.
Researchers found that patients taking TNF inhibitors reported better energy levels and mood, while those on IL-6 and JAK inhibitors showed improved physical functioning. This suggests different drug classes offer distinct advantages across quality-of-life domains.
A new study reveals that electroconvulsive therapy (ECT) can lead to significant negative impacts on standard of living, personal relationships, and even brain damage. Relatives and friends of ECT patients report long-term effects including memory loss, emotional blunting, and loss of independence.
Prenatal stress alters signaling pathways involving corticosteroids in brown fat tissue, potentially blunting the metabolic benefits of exercise. The study highlights the importance of considering maternal stress context in developmental metabolic programming.
A survey of 286 relatives and friends found that 45% experienced improvement, while 42% saw worsening symptoms. Many reported memory loss, difficulty concentrating, and relationship problems after ECT.
SourceWiley·JournalPsychology and Psychotherapy Theory Research and Practice·DateApr 22, 2026
A new study found that prostate cancer overdiagnosis increases with age, with low rates in younger men and high rates in older men. The study suggests that targeted PSA testing or screening policies for men in their 50s and early 60s may be more effective.
Researchers found that firms adopting GitHub Copilot increase hiring of software engineers, with new hires exhibiting more non-programming skills without sacrificing coding ability. The study suggests generative AI is expanding opportunities in the software workforce, not narrowing it.
A study of 19,711 Chinese students aged 6–16 found that rural children are more likely to experience emotional and psychological problems, while urban children exhibit behavioral symptoms. The findings highlight the need for region-specific interventions to address unique challenges.
A new study found that kratom exposures reported to US poison centers increased 6,500% between 2010 and 2023, with severe outcomes rising from zero cases to 158. States with kratom bans had lower rates of exposure and healthcare use compared to those with regulations.
Researchers at Tohoku University successfully measured the attempt time in nanomagnets for the first time, finding it to be 4-11 nanoseconds. This value can serve as a more accurate foundation for developing and evaluating the stability of magnetic devices.
A Canadian nephrologist shared common-sense, patient-centered solutions to address inequities in organ transplantation. His team co-developed practical approaches, including culturally safe spaces, navigation support, and storytelling through videos featuring Indigenous patients.
Experts weigh the pros and cons of an upper age limit for lung transplants, citing concerns over organ shortage and quality of life. Some argue that setting a hard age limit ignores biological variability and comorbidities, while others suggest increasing donor supply and utilization could solve the issue.
The number of pediatric lung transplants is expected to decline as highly effective therapies for cystic fibrosis reduce the need for transplantation. Complex cases with multi-system disease and severe cardiopulmonary compromise are on the rise, requiring highly specialized teams and close collaboration.
A new global allocation system is being proposed to address inequities in organ allocation for heart transplants. The proposal aims to reduce disparities and ensure no viable donor heart goes unused globally.
Recent AI tools offer surgeons assistance in complex decision-making by analyzing donor hearts and providing a data-driven approach. This could lead to increased efficiency in the donor process, reducing the likelihood of hearts going unused due to time constraints.
A recent study published in Frontiers in Pediatrics has found that preschool children born with heart defects are at a greater risk of developing behavioral problems, including ADHD and peer relationship issues. The study suggests that a cognitively stimulating home environment may help reduce this risk.