A recent study from Lancaster University reveals that AI systems like ChatGPT can learn to mirror human impoliteness, potentially escalating into verbal violence. The research tested ChatGPT's ability to respond to real-life impolite interactions, finding it often produces more impolite behavior than humans.
A new catalyst converts carbon dioxide into carbon monoxide under mild conditions, offering a potential path toward future low-energy carbon recycling technologies. The catalyst uses vibrational energy to drive chemical reactions, boasting high efficiency and selectivity for CO conversion.
The new principles aim to guide boards in navigating the opportunities and risks of AI, with a focus on accountability, trust, and long-term value creation. They cover five key areas: strategic oversight, active technology and security oversight, workforce transformation, building trustworthy AI, and the board's role in governance.
A novel MOF-derived nanoconfined hollow polyhedral bimetallic sulfide heterojunction exhibits enhanced light harvesting efficiency and promotes rapid tetracycline degradation, with a kinetic rate constant five times higher than pristine Ag2S. The material maintained over 90% efficiency in real water matrices.
New research identifies Smoothened as a regulator of dopamine-acetylcholine timing, influencing learning, motivation, and behavioral flexibility in adulthood. The study found that animals lacking Smoothened learned motor tasks more quickly but were less sensitive to changes in effort or reward timing.
Researchers have forecasted a super El Niño event toward the end of 2026, driven by a rare and extreme surface annular warming pattern in the tropical Pacific. The current heat content buildup alone would generate a moderate El Niño, but adding the influence of annular warming intensifies it into the super category.
Researchers at LMU Munich have overcome two major hurdles in working with perovskite quantum dots: stabilization in solution and precise control of their growth. By using Gemini ligands, they created stable quantum dots that can disperse in polar solvents and exhibit high photoluminescence quantum yields.
The study found three distinct types of climate supporters: activists, anxious individuals who want to help but struggle with motivation, and hierarchy enhancers who use radical tactics for competitive reasons. Understanding these differences can inform effective communication strategies for climate movements.
Researchers at Kumamoto University discovered that combining cardiac Computed Tomography (CT) scan markers can identify patients at highest risk for future heart failure and death. The 'delayed phase' scan detects localized scarring and subtle damage throughout the heart muscle, providing a synergistic view of heart health.
A new study provides the first direct evidence of cuckoo egg-laying behaviour in cavity nests, rejecting a centuries-old myth about egg-carrying. Cuckoos use two distinct strategies to parasitize host nests, involving trade-offs between accuracy and risk.
A Linköping University study shows that playing with dogs for just a few minutes a day can significantly improve the emotional bond between owners and their pets. Dog training did not have the same effect, suggesting that playtime is crucial for building strong relationships.
New research suggests that federal housing assistance may lead to better two-year survival chances among older men with prostate cancer. The study found a 12% lower risk of death in men who received housing assistance compared to those without it.
A longitudinal study of 156 Ukrainian amputees found that most experience steady improvements in pain, anxiety, and depression over time. The study revealed distinct patterns of post-amputation pain, with phantom limb pain linked to psychological distress and residual limb pain linked to depression.
Researchers have found that asphalt releases volatile organic compounds (VOCs) into the air, which can cause respiratory problems and even lung cancer. As pavement ages, these VOCs become more toxic and can lead to neurological damage. Scientists are working on developing less-toxic asphalt formulations using algae.
A new study found substantial changes in cane toad body size and shape have developed rapidly in response to environmental pressures on Ishigaki Island in Japan. The toads there are heavier and larger than those in Australia, with wider heads and shorter arms and longer legs.
A new study confirms that trilobites' feather-like structures attached to their limbs functioned as sophisticated gills, allowing them to extract oxygen from seawater. The research resolves a long-standing controversy over the respiratory capabilities of these ancient arthropods.
Researchers detect early signs of immune and neurological disruption in sunflower sea stars before physical symptoms appear, shedding light on the mysterious disease. The study identifies Vibrio pectenicida as a driver of the disease, but notes that its direct link to genomic changes remains unclear.
New Oxford analysis finds that up to 90% of industrial energy demand could be electrified with existing technologies, but policy failures and technology risks hold back deployment. Electrification offers a pathway to stable and resilient energy costs, reducing exposure to geopolitical disruption and price volatility.
Researchers found that women with prediabetes had persistent changes in gene expression in fat tissue after bariatric surgery, leading to impaired lipid metabolism and greater weight regain. Despite clinical improvement, these molecular alterations may reduce the ability of adipose tissue to adapt after weight loss.
According to a recent study, about half of the US population expresses democratic neutrality, which can enable antidemocratic outcomes. This neutrality is concerning as it can be associated with authoritarianism, tolerance of norm violations, extremism, distrust, and obscuring antidemocratic views.
Researchers at Texas A&M University have demonstrated a new approach to light-driven motion, showing that lasers can be used to lift and steer objects in multiple directions without physical contact. The breakthrough enables travel to Alpha Centauri within roughly 20 years.
The American College of Cardiology recognized 20 individuals from eight countries for earning the Fellow of ACC (FACC) designation. The award reflects a strong commitment to improving patient care and advancing cardiovascular research.
A new technique uses a single image to forecast solar panel energy production and maximize output. The method estimates the amount of energy that will be produced based on the angle of the sun, shadows, reflections, and weather patterns, allowing for more accurate placement and optimization of solar panels in urban areas.
The new clinical practice guideline from the American Academy of Sleep Medicine provides evidence-based recommendations on combining behavioral-psychological and pharmacological therapies to treat chronic insomnia disorder in adults. The guideline suggests that CBT-I by itself is the most efficacious first-line treatment for insomnia, ...
Wiley has released additional data to its IR and Raman spectral libraries, significantly broadening compound coverage. The new release includes mineral spectra from the American Museum of Natural History, supporting researchers in making informed scientific decisions.
A new white paper by TaMika Fuller and Victoria Lender identifies evidence-based strategies to support working caregivers, including flexible policies and caregiver support systems. Implementing these strategies can strengthen retention, performance, and long-term workforce stability.
A new study shows that combining biochar application with moderate water table management can significantly reduce greenhouse gas emissions from agricultural peat soils. Biochar consistently lowers carbon dioxide emissions and suppresses methane production, making it a promising strategy for climate mitigation.
Researchers found that tumor genetics alone did not explain which patients responded to combination therapy, but rather the tumor's immune environment. Patients with active networks of cancer-killing T cells were more likely to benefit from treatment, while those with dense clusters of plasma cells were less likely.
Researchers identify calcium as a key chemical signal that triggers immune cells during obsessive-compulsive and anxiety-related behaviors. This discovery establishes a new framework to study how anxiety arises and persists through calcium signals in microglia, potentially leading to targeted therapies.
Scientists at MUSC Hollings Cancer Center mapped the architecture of healthy breast tissue to uncover early biological changes linked to cancer risk. The study found that body weight and breast density shape the underlying structure of breast tissue, offering new clues about how cancer risk may develop long before tumors form.
Researchers discovered a powerful molecule called miR-181d that weaks tumors and helps the immune system fight back against glioblastoma. The study found that tumors in 'exceptional responders' contain higher levels of miR-181d, which blocks cancer cells' ability to repair DNA damage.
The Frontiers Planet Prize has announced its 25 National Champions, who offer scalable, evidence-based solutions to the planetary crisis. The report highlights the urgent need for national and multilateral policies to incorporate these pioneering scientific solutions.
Researchers uncovered previously unknown features in the limb musculature of the macaroni penguin that help explain its efficient movement on land and underwater. The study found modified key wing muscles and a unique configuration of shoulder muscles giving penguins an 'underwater flying' wing stroke.
Researchers have found that apples evolved through ongoing interactions with wild species, shaping key characteristics such as flavor and disease resistance. Wild apple trees remain a critical resource for developing new varieties better suited to withstand disease and climate change.
The research team developed a novel AI pathology analysis system named PRET that can accurately recognize multiple types of cancer using only a minimal number of samples. PRET outperformed existing methods in 20 tasks, achieving high diagnostic accuracy rates and stable generalizability across different populations and regions.
A large cohort study found that older adults who report difficulty standing up from a chair are more likely to experience mental health challenges, joint problems, and decline in quality of life. The study analyzed data from over 50,000 adults aged 50 and above across 15 European countries.
Researchers developed a cancer assessment tool that can identify high-risk patients and specific cell populations linked to their risk. The tool, called scSurvival, predicts survival outcomes more accurately than traditional methods by analyzing single-cell data at cellular resolution.
A new study found that people with Parkinson's disease and those in its prodromal stage often report 'brain fog' despite normal objective cognitive scores. The researchers suggest targeting anxiety and depression may help improve quality of life.
A new framework uses satellite imagery and machine learning to detect tillage practices over large areas and long time periods. The approach has been used to estimate tillage percentage across the U.S. Midwest from 2000 to 2022, revealing clear differences in no-till adoption by crop and region.
The SETI Institute's new initiative explores the global scientific, philosophical, and societal implications of discovering life beyond Earth, connecting experts in various fields. The Discovery and Futures Lab aims to anticipate and guide humanity's responses to this discovery.
A new method called scSurvival uses single-cell genetic data to identify which cells inside a tumor are most strongly linked to patient survival. The approach pinpoints harmful and helpful cell populations that can drive disease progression, enabling better understanding of why patients with the same cancer have different outcomes.
The book highlights the importance of sustaining innovation in sectors such as semiconductors, biotechnology, and critical minerals to drive economic growth and national security. By rebuilding domestic manufacturing and leveraging new technologies, the US can regain leadership in these areas and capture a $4 trillion market.
Researchers at the University of Colorado Anschutz discovered that cancer drugs impact a specific protein regulating taste buds. This finding could lead to new treatments preserving taste function in cancer patients.
A new study found that FDA 'healthy' labels increase consumer selections of healthier snacks and command a price premium. The study, led by researchers at Oregon State University, examined consumer purchasing preferences for snack products with and without healthy labels.
University Hospitals is the first US health system to achieve ISO 9001 certification for its corporate headquarters and the first in Ohio with all hospitals certified. The achievement demonstrates a systemwide commitment to consistency, accountability, and continuous improvement.
Researchers developed a new method to recover critical minerals using simple magnets, which streamlines the process while reducing energy consumption. The technique exploits small differences in magnetic susceptibility to drive selective transport and separation.
A new study found that high school students who perceive sun protection as inconvenient or uncomfortable are less likely to engage in sun-safe behaviors. Teens who view tanning as enhancing appearance or social appeal also tend to neglect UV radiation protection.
A new FeS2/MoS2 heterostructure design enables rapid water treatment while maintaining long-term stability and efficiency. The system regenerates dual active sites through internal electron transfer, supporting multiple reactive oxygen species for pollutant degradation.
Researchers introduced QCell, a curated collection of 525,000 new quantum-mechanical calculations for biomolecular fragments. The dataset addresses the limited coverage of nucleic acids, lipids, and carbohydrates, enabling reliable simulations of critical biological processes such as DNA dynamics and membrane behavior.
A new study by the University of Helsinki finds that the carbon footprint of milk production is 41% higher when soil carbon changes are included. Soil organic matter can either sequester or release carbon, and its impact on climate change should not be ignored.
Dr. Aditya Bardia has been elected to the American Society for Clinical Investigation for his outstanding contributions to research and patient care in breast cancer treatment. He is advancing precision medicine therapies through antibody-drug conjugates and liquid biopsy technologies.
A Concordia study reveals that black soldier flies can survive and thrive on goose feces, producing valuable biomass for composting and organic fertilizer. The insects' waste also serves as a nutritious fertilizer for duckweed, improving its growth rate and root system.
Researchers mapped how Sox9 guides cartilage formation in mouse embryonic limbs, finding that it dynamically targets different genes depending on developmental timing and cell type. The study provides a foundation for understanding skeletal development and may contribute to future research on bone and cartilage diseases.
A mild chemical strategy enhances interfacial bonding and pore structure in biomass-based magnesium cement materials, leading to improved mechanical strength and thermal insulation. The approach promotes more uniform pore distribution, stabilizes the foam structure within the composite, and reduces environmental burden.
A new study reveals that AI's strength lies in teamwork with humans, processing data but relying on people for context and ethical decisions. The research emphasizes the importance of human oversight and responsibility in AI-driven decision-making.
A study of nearly 6,000 people found that when people are presented with viewpoints they disagree with in a pro-support frame, they tend to be less open to the idea. However, when framed in oppositional terms, they are more likely to engage. Researchers suggest changing argument framing can help improve dialogue.
A new phase in the corona-development has been identified, with recent SARS-CoV-2 variants spreading less rapidly worldwide and BA.3.2 infecting young children more frequently than other strains. This suggests that global immunity from vaccination and infections may be making it harder for new variants to spread.
A new study has found that postmenopausal white women with higher genetic risk of obesity regained weight about two times faster than those with lower genetic risk. Despite this difference, Black women in the study regained weight at a similar rate, regardless of their genetic risk.
A study by Universitat Oberta de Catalunya found that digital platformization leads to a fragmentation of pupils' knowledge, alterations in socio-cognitive conditions, and disruptions in learning times. Teachers report concerns about superficial reading, interrupted didactic continuity, and reduced students' personal involvement.
Researchers at DTU discover three types of lactic acid bacteria that can effectively produce plant-based yoghurt alternatives, inhibiting harmful bacteria and breaking down sugars. The bacteria also improve the product's texture and extend shelf life.
Researchers developed a platinum-based catalyst supported on oxygen-vacancy-rich cerium oxide (Pt/CeO2–Vo) to enhance hydrogen activation. The catalyst achieved a pyrrolidone yield of 95.2% within one hour, with high formation rates and excellent stability.
Mechanobiology reveals how physical forces govern cells, tissues, and diseases, leading to breakthroughs in cancer, fibrosis, orthopedic injuries, and vascular diseases. The field is also pioneering mechanical reprogramming and mechanogenetics, enabling personalized mechanical interventions.
A recent study found that antibiotic-resistant bacteria are present in the gut microbiomes of American black bears in eastern North Carolina. The researchers also discovered that these pathogens can be dispersed through bear feces, making the bears a potential indicator species for environmental changes.
New research from Trinity College Dublin found playing an instrument, taking a foreign trip, and socializing boost cognition in midlife. Lifestyle interventions can strengthen cognitive reserve decades before disease onset.
Researchers found that crabs' iconic sideways walk originated from a single, forward-walking ancestor around 200 million years ago. This rare innovation likely contributed to the ecological success of true crabs by making their escape direction unpredictable.
A new multicenter study finds that reoperative surgical mitral valve replacement demonstrates significant long-term survival benefits over transcatheter mitral valve-in-valve procedures in patients with failing bioprosthetic valves. At five years, rSMVR patients had lower mortality and more favorable valve performance.
A study by Geisel School of Medicine researchers identifies specific macrophage populations that help coordinate anti-tumor immunity, while others support tumor growth. By selectively targeting these immune programs, cancer treatments may be improved without eliminating entire immune cell populations.
A study on Spanish transhumance identifies three distinct types of systems, aligned with agroecological principles, offering insights into sustainable livestock farming. The findings highlight the need for greater political support and a regulatory framework to protect this ancient practice.
Measles outbreaks are accelerating globally, with declining vaccination rates and gaps in routine immunization coverage contributing to the resurgence. The disease can cause serious complications, including pneumonia, encephalitis, and death, particularly in young children and immunocompromised individuals.
Researchers found that brains consider grammatical constituents when anticipating next words, unlike AI systems which rely on predictive context. The study used magnetoencephalography and behavioral tasks to measure brain activity and word prediction accuracy.
The ORNL team is developing AI-enabled pixel detectors that can process massive data streams directly at the source. Spiking neural networks will be used to identify patterns and extract valuable signatures from particle interactions in real time.
SGLT2 inhibitors reduce proximal tubular sodium reabsorption by suppressing NHE3 via the SGLT2-MAP17-NHE3 microdomain. This effect is context-dependent, with distal compensation (NCC upregulation) possible. Clinical evidence shows reduced ascites, fewer paracenteses, and improved natriuresis.
Researchers discovered a biomarker that can predict disease progression and mortality in patients with severe heart failure. Mid-regional pro-adrenomedullin (MR-proADM) levels are associated with greater disease severity, mortality, and heart failure events.
The Kura-Araxes culture's multi-ingredient cuisine highlighted the central role of dairy products, fruit, and grape-based beverages. The discovery sheds new light on the daily life and culinary traditions of these communities, suggesting a low level of social stratification.
Researchers have discovered a new species of basal medusozoan, Paleocanna tentaculum, in fossil specimens found in Saint-Joachim, Quebec. The ancient creature, closely related to modern jellyfish, is a rare find due to the limited preservation of soft-bodied organisms.
The study sequenced and decoded the complete genetic information of rose plants, producing the first rose pangenome. This reveals a complex evolutionary history shaped by gene transfer and environmental adaptations.
A team of scientists at the Hackensack Meridian Center for Discovery and Innovation (CDI) has made a significant breakthrough in treating deadly non-tuberculous mycobacteria (NTM) infections. They have developed new compounds, including rifamycin candidates, which show promise in treating M. abscessus and other rapidly growing NTMs.
Researchers at Umeå University have identified NUP98 and NUP153 as key host factors in orthoflavivirus infection, which replicates in the cytosol of human cells. The proteins play a crucial role in viral replication and protein production, and their interaction with viral RNA regulates structural and non-structural protein ratios.
Binghamton University's new initiative aims to advance artificial intelligence for the public good by educating students on foundational AI principles, workforce applications, and ethical considerations. The three-year, $900,000 program includes a free online microcredential and student research opportunities.
The study found that women's cardiovascular disease is biologically different from men's, with greater sensitivity to cumulative risk exposure and more severe downstream consequences. Researchers emphasize the need for continued investment in CVD research to address sex-specific disease mechanisms and life-course risk accumulation.
The Individual Brain Charting project has released its fifth update with a new set of cognitive tasks, expanding the dataset to 40 hours of scanned data per participant. This provides an exceptionally rich resource for studying individual variability in brain organisation and understanding brain function.
A new international survey reveals that adults with hypophosphataemic osteomalacia face a substantial disease burden, often under-recognised. The study calls for improved awareness, education, and coordinated care to ensure timely diagnosis and optimal treatment.
A study by the University of Kansas found that high school journalists learn business skills through practice and experiential learning, even if business concepts are not directly addressed. Student media advisers reported financial pressures and stressed the need for improved financial literacy education.
The study uses CRISPR/Cas9 to modify the transcriptional repressor SlMYB32, leading to increased flavonol and flavanone production in tomatoes. Key genes associated with these compounds are up-regulated in SlMYB32 mutants.
Terrence Sejnowski receives Scientific Breakthrough Award for his foundational development of Boltzmann machines, providing the architectural bedrock for deep learning and generative AI. His work has had a profound impact on modern artificial intelligence and tools like ChatGPT.
Researchers developed a new scale to measure the use of evidence in decision making, capturing four sources of evidence. The Evidence-Based Management Source Utilization Scale (EBM-SUS) shows promise for increasing transparency, accountability, and effectiveness in organizational management.
Researchers at Saarland University are developing smart implants that can continuously monitor and visualize the healing process of fractures. These customized implants can dynamically adapt to the healing process by becoming stiffer or more compliant as required, promoting bone regeneration through micromechanical stimulation.
A VHIO-led study identifies epigenetic changes caused by diet, tobacco, and pesticide exposure as risk factors for early-onset colorectal cancer. The study, published in Nature Medicine, confirms the influence of lifestyle and environmental exposures on cancer development in younger patients.
A new cobalt-based dual-atom catalyst significantly enhances oxygen reduction reaction performance while avoiding precious metals. The catalyst achieves remarkable catalytic activity and retains durability, enabling outstanding energy performance in zinc-air batteries.
Researchers develop a nature-inspired hybrid material that produces high-quality therapeutic proteins with nearly tenfold higher efficiency than traditional methods. The material's unique design enables it to adapt to different environments, alleviating hypoxic stress and activating cellular functions.
A recent study found that children from rural China are more prone to emotional issues, while urban children show more behavioral problems. These findings highlight the need for targeted interventions and underscore the impact of environment on mental health outcomes.
Scientists have discovered a natural extract that enhances the effectiveness of traditional sunscreens, providing longer-lasting protection against UV radiation. The new generation of sunscreens also offers antioxidant benefits, reducing the risk of skin cancer and premature aging.
The Insilico Medicine Longevity Board aims to accelerate the development of therapeutics targeting the biological processes of aging. The board, led by Andrew Adams, will oversee AI-enabled aging research and drug discovery.
Researchers develop new concept to accurately model wind turbine loads, focusing on local gusts' impact on material fatigue. This enhances turbine design and efficiency by reducing uncertainties in load estimations.
Researchers at University of Galway discovered a new therapeutic approach to combat Alzheimer's disease. They found that stimulating the brain's efficiency and balance may help alleviate cognitive decline and memory impairment. By blocking the activity of GABA receptors, they can reverse Alzheimer-like effects and improve cognitive per...
Researchers are unlocking secrets of Mechanohealth, a new paradigm focusing on maintaining the body's natural mechanical balance to prevent and treat disease. Studies have shown that macrophage mechanics directly determine anti-tumor activity and fibrosis can be reversed by disrupting key mechanical feedback loops.
A new species of coelacanth has been identified from a 150-year-old fossil, bridging a 50-million-year gap in the evolutionary history of Latimeriidae. The discovery was made using modern imaging techniques and has provided crucial insights into the evolution of one of the world's most iconic fish lineages.
A new study introduces the eLTER Framework of Standard Observations, a structured system to support consistent long-term environmental observation across Europe. The framework strengthens collaboration and improves data interoperability for studying gradual environmental changes.
Researchers found that a deaf person's brain can reorganize sensory systems through selective deactivation, not just increased activation. The auditory cortex in deaf individuals responds to visual stimuli with organized deactivations, representing visual spatial features.
The EVApeCognition Dataset is the largest and most comprehensive collection of experimental studies of great apes' cognition and behavior available globally. Researchers compiled over 262 experimental datasets from 150 publications, enabling unprecedented examination of how great apes think, learn, and understand their environment.
Researchers found that listening to one-minute recordings of forest sounds made people feel better, reporting more positive emotions and less stress. Local temperate forests produced the strongest effects, with familiar sounds triggering stronger feelings of awe and calm.
The University of Manchester has been recognized for its significant contribution to computer science with the third IEEE Milestone Award, honoring the invention of Manchester Code in 1948-1949. The code's self-clocking design enables reliable transmission and remains a key feature in modern digital systems.
Researchers developed a Variational Level Set Autoencoder (VLSet-AE) to automate contour recognition in SEM cross-sections of DRIE structures. The model achieved high precision, recognizing critical structural features with low average prediction error of 3.65% and correlation coefficient of 0.998.
Researchers at the University of Manchester have found that terrestrial hot spring microbiomes can transform industrial CO2 waste into biomass and other valuable compounds. This discovery could enable the production of value-added products directly from CO2-rich waste streams, reducing emissions while generating economic value.
Researchers discover cancer-driving genes in microglia of Alzheimer's patients, suggesting a link between blood cancers and the neurodegenerative disease. The findings could lead to new diagnostic tools and therapeutic options for Alzheimer's.
A study published in Nature Communications reveals how immune cell networks contribute to liver damage and fibrosis. The research team identified a key interaction between dendritic cells and γδ T cells, triggering pro-inflammatory signals that amplify inflammation.
Lindsay Squeglia, Ph.D. of the Medical University of South Carolina received the 2026 ACTS Award for Supporting an Excellent Translational Science Workforce. She is a leading figure in substance use prevention and adolescent brain development research.
A recent study from the University of Eastern Finland found that people with Parkinson's disease are using psychotropics more frequently than controls, even before diagnosis. The use of psychotropic medications increases as the disease progresses, reflecting emerging non-motor symptoms and worsening disease progression.
Researchers at KAIST developed a new technology using spin waves to process signals, reducing heat generation and power consumption. This breakthrough enables instantaneous frequency switching and is expected to pave the way for smart devices with less heat and longer battery life.
Researchers found AI voice clones to be up to 20% more intelligible than humans in various testing scenarios, including noise, age, and accent. This breakthrough raises questions about the potential applications of voice cloning technology.
A study found that long-term exposure to wildfire smoke was significantly associated with an increased risk of developing lung, colorectal, breast, bladder, and blood cancer. The risk increased with every additional microgram per cubic meter of fine particulate matter in the air.
Twenty-three young investigators from 16 countries received the ESCEO-IOF Young Investigator Awards for their outstanding abstracts submitted to the WCO-IOF-ESCEO 2026 Congress. The awards aim to support and attract young researchers to the field of musculoskeletal research.
The International Osteoporosis Foundation has awarded Professor Roland Chapurlat the prestigious IOF Olof Johnell Science Award for his seminal contributions to understanding and managing osteoporosis, osteoarthritis, and skeletal rare bone diseases. He is recognized as one of the leading clinical academics in the field worldwide.
Researchers developed a new method to identify intricate RNA structures that are likely to have significant biological functions. The multi-site DMS-MaP approach allows for direct measurement of RNA folding in cells, revealing key 3D structures and protein binding sites.
A study found that early myocarditis onset after immune checkpoint inhibitor therapy significantly increases the risk of death from treatment-related causes. Patients who developed co-occurring myositis and myasthenia gravis were also at a higher risk, with some cases leading to fatal outcomes.
A recent review highlights how AI enables precision treatment, continuous monitoring and individualized prognostic modeling for heart failure patients. AI integrates large-scale structured electronic health records and multimodal imaging to characterize cardiac structure and function, enhancing diagnostic accuracy.
Researchers at Ben-Gurion University found that altering water source distribution in a desert ecosystem improved mating structure and increased genetic diversity in wild populations. By establishing more territories for reproducing males, changes in resource management boosted population's variance effective population size.
Research found that gender-diverse teens reported higher rates of psychological stress and psychotic-like experiences, which can lead to depression, anxiety, and other serious mental health disorders. Bullying and unsupportive legislation drove these findings.
Researchers found that Cathepsin K (CTSK) reduces liver fibrosis by blocking the TGF-β/Smad pathway, which activates hepatic stellate cells. CTSK also induces apoptosis in these cells, contributing to anti-fibrotic effects.
A recent study from the University of Tartu found that young children who spend more time on screens and less time talking with adults tend to have weaker language skills. In contrast, daily interaction – rather than screen limits alone – plays a key role in early language development.
Nine European high school students completed a six-day simulated Mars mission in Portugal, operating rovers and conducting scientific experiments. The EXPLORE-2 mission aimed to develop young Europeans' STEM skills and team management capabilities, with participants designing their own mission plans and making operational decisions.
Researchers found that intralesional nivolumab reduced lesion size by an average of 60% and achieved complete pathologic response in 6 patients. The treatment also showed promise in treating high-grade and low-grade dysplasia, with 82.13% of treated lesions remaining cancer-free after 12 months.
Five fellows will receive funding for four years to study hard-to-treat pediatric cancers, reduce treatment toxicity, and develop innovative therapies. Their research focuses on Ewing sarcoma, leukemia, kidney cancer, and immune system vulnerabilities.
Professor Radmila Matijevic received the IOF CNS Medal for her outstanding work in advancing bone health awareness, diagnosis, and management. Her contributions to osteoporosis research and clinical practice have improved patient care in Serbia and the wider Balkan region.
A new treatment using low-dose nivolumab injections into precancerous oral lesions significantly reduced lesion size and risk of cancer progression. The study showed a 60% average reduction in lesion size and complete pathologic response in six patients, with no dose-limiting side effects.
The study reveals that Chinese characters exhibit unique mechanical properties due to their geometric structures. The researchers found that curves, crossbeams, and gradation in the characters improve the material's stiffness and flexibility.
A retrospective cross-sectional study found significant associations between unsecured firearm storage and heightened suicide risk in US Army service members. Carrying a weapon other than a firearm also linked to elevated suicide risk, suggesting that any type of weapon carrying behavior may indicate increased vulnerability.
A cohort study found that bullying and restrictive legislation were associated with higher rates of psychotic-like experiences in gender-diverse youths. The study suggests that supportive environments and policies can help alleviate mental health concerns among this population.
A Japanese study examines the long-term effects of COVID-19 lockdowns on individuals with glucose intolerance, revealing a clear divergence in clinical trajectories among those who worsened and improved. Flexible lifestyle adaptation is crucial for restoring metabolic health, suggesting personalized support may improve glycemic control.
Guideline recommendations for immune checkpoint inhibitor-induced liver injury (ICILI) vary, with corticosteroids and biopsy indications differing among organizations. Rechallenge after ICILI is feasible in selected patients, with low recurrence rates, but standardized algorithms are needed.
The 12th ARDD meeting emphasized the importance of reversing biological age and identifying molecular mechanisms that can be targeted to modify them. Researchers presented new biomarkers and AI-designed proteins to develop novel therapeutics, with a focus on integrated, multi-targeted therapeutic strategies.
Researchers developed a novel adhesive conduit inspired by pinecones that can adapt to natural nerve geometries without suturing. The conduit achieved robust nerve regeneration, functional recovery, and minimized secondary complications in animal models.
A study of 371 patients with autoimmune hepatitis (AIH) found that extrahepatic autoimmune diseases (EADs) are common, particularly Sjogren's syndrome and autoimmune thyroid disease. Patients with EADs had a poorer early treatment response but achieved comparable outcomes after six months.
The American Kidney Fund has awarded over $6 million in grants to researchers Dr. Sophie Claudel and Dr. Liz Kiernan, exploring the connection between kidney disease and cardiovascular health. Their studies aim to develop new treatments and improve diagnostics for patients with chronic kidney disease.
Researchers have developed a new microscopy method that uses polarized light and a magnetic field to detect malaria parasites in blood. The method provides quantitative information and can be used for faster and more objective detection of malaria.
A new study by the University of Technology Sydney and Massachusetts General Hospital/Harvard Medical School found that dietary patterns and a history of appendix removal are strongly associated with Alzheimer's risk. The research suggests that a healthy gut microbiome plays a crucial role in protecting the brain from neurodegeneration.
A study by Griffith University found microplastics and nanoplastics reduced plant growth and entered plant tissues through soil, raising concerns about food safety. Fibre-shaped plastics had the most effects on plant growth, with nanoparticles transported within plants.
Researchers at Kyoto University found that chaotic component of heartbeat variability is sensitive to cognitive brain activity, providing a new indicator of brain-heart interaction. Chaos-based measures revealed clear and reproducible changes associated with task engagement, contrasting with conventional HRV indices.
A Tohoku University research group developed an AI model that estimates retinal age from a fundus photograph, reflecting biological aging and potential disease risk. The model is non-invasive and can be used as a screening aid, identifying patients who may need further health assessments.
The new centres will focus on studying the complex relationship between culture, biology, and technology, aiming to accelerate discovery of new medicines and materials. Researchers from NTU, MPG, and Singapore institutions will collaborate on interdisciplinary projects.
A study by the University of Vienna reveals that European colonialism has left a lasting impact on the threat to languages and species. Island regions, such as Oceania and East Asia, are disproportionately affected due to their small size and vulnerable ecosystems.
Researchers found that polyploid cells activate a stress signaling pathway causing increased mobility and engulfing neighboring cells. This behavior can promote tumor growth and therapy resistance in aggressive cancers.
Researchers have created a novel sorbent made from chitosan/cellulose acetate and bentonite composites that show promise for cleaning up oil spills. The beads are floatable, biodegradable, and environmentally compatible, making them an efficient and cost-effective solution.
The article highlights how advances in remote monitoring and portable medical technology are dismantling traditional hospital walls. Hospital-at-Home programs offer a scalable solution to acute care delivery, resulting in lower costs, reduced readmission rates, and improved patient outcomes.
A new study by the University of Sydney found that toddlers' pretend play ability is significantly associated with fewer emotional and behavioral difficulties at primary school. The researchers analyzed data from over 1400 Australian children and found that stronger pretend play ability among two- to three-year-olds was linked to bette...
Researchers developed two heart failure risk assessment models using large international health databases, enabling early detection of the disease. The SCORE2-HF model estimates up to 30-year risk of heart failure in the general population, while the SMART2-HF model assesses risk for people with a history of cardiovascular disease.
Researchers at DZNE discovered complex, situation-dependent interactions between glioblastoma cells and microglia in the brain. The study found that microglial activity changes as tumors spread, influencing containment and spread of the disease.
A new analysis found that prescriptions for curable hepatitis C drugs have declined sharply in recent years, leaving millions without treatment. The researchers urge swift actions to deliver the drugs to those who need them, including increased screening and system-level changes.
Researchers found that pill bugs do not simply incorporate ingested CaCO3 minerals as building blocks. Instead, they actively restructure CaCO3 within their bodies to form their tergite cuticles. This study highlights the biological control underlying mineral formation and provides new insights into biomineralization mechanisms.
A ketogenic diet has been shown to improve beta-cell function in patients with type 2 diabetes by decreasing proinsulin secretion and reducing pancreas stress. This improvement is associated with changes in the proinsulin-C-peptide ratio, a biomarker of pancreas stress.
The Pediatric Academic Societies (PAS) recognizes 46 outstanding trainees and early career professionals for their contributions to pediatric research. The recipients will receive complimentary registration and a travel stipend to attend the PAS 2026 Meeting in Boston, Massachusetts.
A new method for treating sewage sludge efficiently creates renewable natural gas while reducing treatment costs by nearly 50%. The process produces pipeline-quality renewable natural gas with minimal CO2 content.
Pediatric low-grade gliomas require distinct treatment strategies, with a focus on molecular diagnosis and age-appropriate treatment. The new Chinese guidelines cover imaging, pathology, surgery, radiotherapy, and systemic therapy, aiming to maximize tumor control while protecting neurodevelopment.
Researchers have developed cyborg animals that integrate machine and biological intelligence, enabling them to execute human commands while retaining natural advantages. Key findings include advancements in control paradigms, miniaturized electronic backpacks, and self-sustaining energy harvesting technologies.
Researchers created a video to educate journalists on key elements of reporting scientific studies, resulting in more accurate headlines. The study found that journalists who watched the video were 64% more likely to write accurate headlines than those who did not.
New findings render antibiotic-resistant bacteria vulnerable by disabling individual resistance and cross-protection. This approach offers new possibilities for treating resistant infections associated with cystic fibrosis and may inform the treatment of a broad range of antibiotic-resistant infections.
A large multiethnic study identifies genetic factors associated with developmental dysplasia of the hip (DDH) and its progression to osteoarthritis of the hip. Variations in COL11A2, CALN1, and TRPM7 genes were found to be common to both DDH and hip OA.
A new study found that an elevated NLR is significantly associated with both long-term and short-term risk of Alzheimer's and dementia. High NLRs were more prevalent among Hispanic patients and women, suggesting potential genetic or social factors at play.
Researchers found a distinct pattern of immune activation early in infection among individuals who later developed broadly neutralizing antibodies, suggesting interactions between the immune system and other infections may be linked to HIV response.
A study published in the Journal of Aggression, Maltreatment & Trauma found that feeling safe with a trusted adult during childhood reduces the risk of depression, chronic disease, and poor health. The presence of protective adults significantly mitigates the long-term impact of abuse.
Astronomers have identified the edge of the Milky Way's star-forming disc for the first time, finding that most star formation happens within 40,000 light-years of the Galactic Center. This discovery uses a new approach combining star ages with galaxy simulations to pinpoint the boundary.
NASA's Curiosity Mars rover has discovered diverse organic molecules on Mars, including chemicals that could be signs of ancient life. The findings suggest the Martian surface can preserve molecules that could serve as building blocks for life.
Researchers discovered that coffee consumption affects the microbiota-gut-brain axis, influencing mood and stress levels. Decaffeinated coffee improved learning and memory, while caffeinated coffee reduced anxiety and inflammation.
Researchers at John Innes Centre develop rapid seed germination protocol, reducing Ash dieback's impact. This new method has already produced over 2,000 seedlings for trials and research.
The US is not prepared for a mass disaster with multiple burn casualties, experts say. Gaps in everyday burn care for children must be addressed before it will be considered ready.
Colorectal cancer incidence is rising among young individuals in Switzerland, with cancers occurring before age 50 accounting for 6.1% of all cases. The study highlights the importance of awareness and earlier screening to address this trend.
A tiny binding site in the TRPM3 ion channel is found to be crucial for pain signaling, with even small changes affecting its behavior. The study also reveals that patient-derived mutations can alter drug responses, highlighting the need for personalized pain therapies.
A new study reveals a strong link between extreme climate events and the incidence of heart disease among middle-aged and older adults in 157 Chinese cities. Exposure to extreme heat, cold, and precipitation increases the risk of cardiovascular disease, with higher BMI-related risks associated with temperature intensity and cold-induce...
A research group developed an optimized signal transmission system for implantable medical devices, improving accuracy and strength of wireless signals. The approach uses ultra-wideband communication to coordinate multiple implants and reduce signal distortion, enabling more effective healthcare applications.
A new study reveals that over 90% of lead paints sold in Mexico contain hazardous lead chromate pigments, which dominate the market. The widespread use of these pigments poses serious health consequences for children and workers, with alarming levels of blood lead found in Mexican children.