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International Osteoporosis Foundation


New position statement calls for systematic bone health optimization before joint replacement and spinal fusion surgery

A new position statement calls for systematic bone health optimization before joint replacement and spinal fusion surgery. Key findings include the progressive mechanical failure of bone-implant constructs resulting from compromised bone quality, particularly due to osteoporosis.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateJul 20, 2026

Landmark special issue highlights advances in enamel research

The Enamel 11 Symposium-associated special issue explores key findings on enamel development, mineralization, and pathology, highlighting emerging technologies for prevention and repair. The issue provides a comprehensive overview of current research into dental enamel, one of nature's most extraordinary biomineralized tissues.

SourceInternational Osteoporosis Foundation·JournalCalcified Tissue International·TypeCommentary/editorial·DateJun 29, 2026

New review highlights how modern rheumatoid arthritis treatments can protect bone health

A new review highlights advances in preventing bone loss in people with rheumatoid arthritis, showing that modern antirheumatic therapies can significantly reduce both localized erosions and generalized bone loss. Emerging imaging technologies like HR-pQCT have been found to detect subtle bone erosions earlier and more sensitively.

SourceInternational Osteoporosis Foundation·JournalCalcified Tissue International·TypeLiterature review·DateJun 10, 2026

New review highlights ongoing challenges of vitamin D management in inflammatory rheumatic diseases

A new review highlights that vitamin D deficiency is common and clinically important in patients with inflammatory rheumatic diseases, but the current evidence does not support a direct disease-modifying effect. Vitamin D supplementation shows modest benefits in some patients, particularly those with low baseline vitamin D levels.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateJun 8, 2026

International experts call for end to routine reporting of “corrected” calcium

International experts in laboratory medicine, osteoporosis, and chronic kidney disease recommend ending routine reporting of albumin-adjusted ('corrected') calcium. The practice may misclassify patients and compromise care due to unreliable correction formulas and variability in local measurements.

SourceInternational Osteoporosis Foundation·JournalClinical Chemistry and Laboratory Medicine (CCLM)·TypeCommentary/editorial·DateMay 18, 2026

Development of build better bones: A global resource for osteoporosis self management

A new platform, Build Better Bones, offers evidence-based guidance and practical resources for osteoporosis management. The platform, developed by the International Osteoporosis Foundation, provides a trusted place for people with osteoporosis to start their journey, with a focus on exercise, nutrition, and home safety.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeContent analysis·DateMar 16, 2026

Treatment strategies after denosumab discontinuation in non-metastatic breast cancer treated with AI

A new review highlights the need for planned sequential bone therapy to reduce the risk of spontaneous vertebral fractures after denosumab therapy. Denosumab discontinuation can trigger a 'rebound phenomenon' marked by rapid bone turnover, bone loss, and potentially multiple vertebral fractures.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateFeb 10, 2026

First global consensus on managing vertebral fractures in advanced chronic kidney disease

Vertebral fractures are a devastating complication of advanced kidney disease, associated with increased risk of further fractures and cardiovascular events. The first global consensus statement offers practical recommendations for clinicians to identify and manage vertebral fractures in patients with chronic kidney disease stages G4–G5D.

SourceInternational Osteoporosis Foundation·JournalNephrology Dialysis Transplantation·TypeLiterature review·DateJan 26, 2026

Give for your bones: IOF launches new platform to inspire movement and fundraising for global bone health

The International Osteoporosis Foundation unveils a global fundraising and engagement platform called Give For Your Bones, aiming to motivate individuals and organizations to support bone health worldwide. The platform provides creative ideas for fundraising and physical activity challenges, making it easy to support IOF's mission of p...

A practical tool to support harmonization and quality improvement in vitamin D testing

A new study published in Clinical Chemistry and Laboratory Medicine has developed a practical tool to support harmonization and quality improvement in vitamin D testing. The multicentre study evaluates the measurement uncertainty of various 25-(OH)D assays and their ability to detect physiologically relevant changes over time.

SourceInternational Osteoporosis Foundation·JournalClinical Chemistry and Laboratory Medicine (CCLM)·TypeExperimental study·DateSep 11, 2025

Closing the care gap: IOF position paper identifies barriers and solutions to global undertreatment of osteoporosis

The International Osteoporosis Foundation identifies critical global barriers to osteoporosis care, including limited DXA scanning and outdated treatment criteria. The IOF advocates for a paradigm shift in bone health management worldwide, recognizing high fracture risk as a valid criterion for treatment and reimbursement.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateSep 9, 2025

New guidance on the management of aromatase inhibitor-associated bone loss in women with hormone-sensitive breast cancer

The International Osteoporosis Foundation has issued an updated joint position statement on managing aromatase inhibitor-associated bone loss in women with hormone-sensitive breast cancer. The guidelines incorporate recent clinical trials and systematic reviews to provide evidence-based treatment algorithms for assessing fracture risk ...

SourceInternational Osteoporosis Foundation·JournalJournal of Bone Oncology·TypeLiterature review·DateAug 18, 2025

New review highlights impact of diabetes on bone health and fracture risk

A landmark review highlights how diabetes alters bone microarchitecture and increases fracture risk in people with type 2 diabetes, despite normal or elevated bone mineral density. The authors advocate for updated diagnostic tools, including a revised TBS algorithm, to more accurately reflect bone quality in individuals with central ob...

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateJun 18, 2025

Joint consensus highlights the role of bone turnover markers in osteoporosis diagnosis and management

A new consensus paper emphasizes the role of bone turnover markers (BTMs) in diagnosing and managing osteoporosis. BTMs, such as procollagen type I N propeptide (PINP) and β-isomerized C-terminal telopeptide of type I collagen (β-CTX-I), are invaluable tools for predicting fracture risk and monitoring treatment adherence.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateMar 31, 2025

Standardized nomenclature for bone status indices to enhance diagnostic consistency and clarity

A new position paper from the International Osteoporosis Foundation and International Federation of Clinical Chemistry proposes a unified nomenclature for bone status indices to enhance diagnostic consistency and clarity. The guidelines offer a comprehensive framework to unify terminology and improve comparability across studies.

SourceInternational Osteoporosis Foundation·JournalClinical Chemistry and Laboratory Medicine (CCLM)·TypeLiterature review·DateJan 10, 2025

Special issue: Osteogenesis imperfecta from bench to bedside and from cradle to grave

This special issue of Calcified Tissue International presents a collection of critical reviews and original research articles on osteogenesis imperfecta (OI), covering essential aspects of the condition, including its nosology, genetics, and clinical presentation. The contributions also discuss treatment strategies for both children an...

SourceInternational Osteoporosis Foundation·TypeCommentary/editorial·DateNov 29, 2024

IOF position on scientists and societies operating in conflict zones

The International Osteoporosis Foundation (IOF) has released a position paper recommending rules for partnerships with member organizations and scientists operating in conflict zones. A survey of IOF member societies found strong consensus towards maintaining a neutral stance, supporting scientific collaboration and research.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeCommentary/editorial·DateJun 24, 2024

New review provides insights into the impact of osteoporosis and related medications on fracture healing

A comprehensive review examines the impact of osteoporosis on fracture healing and the effects of osteoporosis medications. The study concludes that there is no deleterious effect of osteoporosis medications on fracture healing, and prompt treatment can reduce the risk of secondary fractures.

SourceInternational Osteoporosis Foundation·JournalOsteoporosis International·TypeLiterature review·DateApr 8, 2024

New evidence-based guideline for the management of osteoporosis in men

The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis have issued new guidelines for managing osteoporosis in men. These recommendations cover disease burden, fracture risk assessment, treatment thresholds, and interventions to reduce the substantial morbidity and mortality ass...

SourceInternational Osteoporosis Foundation·JournalNature Reviews Rheumatology·TypeLiterature review·DateMar 25, 2024