A University of Rhode Island professor studied natural selection in Anolis lizards impacted by hurricanes, finding longer limbs and larger toepads increase survival rates. This study confirms hurricanes as a source of episodic natural selection with lasting evolutionary effects.
Researchers discovered the biosynthetic pathway of glycitein, a key soybean isoflavonoid, and its role in plant immunity. They found that GmIF6H1 enzyme catalyzes the production of glycitein, which acts synergistically with glyceollins to defend soybeans against infection by Phytophthora sojae.
The German Federal Institute for Risk Assessment (BfR) is launching a new study module to investigate the influence of parental nutrition on children's eating habits. The study aims to provide insights into how plant-based diets of parents affect the eating habits and food consumption of children.
Researchers simulated the Josephson effect using ultracold atomic gases and observed characteristic Shapiro steps, confirming its universality. The findings enable the study of quantum effects in atomic systems, paving the way for 'atomtronics' and potential applications in quantum computing and medical diagnostics.
A new study reveals the molecular clues behind cassava's better heat handling than potato. Cassava maintains photosynthesis and hormonal balance to withstand heat, whereas potato relies on energy-costly stress repair mechanisms.
The loss of submerged macrophytes, which trap arsenic, can lead to its release into the water upon plant death. This study highlights a previously underestimated process, revealing an overlooked pathway for arsenic contamination.
A new study estimates that the Amazon rainforest could lose up to 38% of its area by the end of the 21st century due to land use changes and climate change. The research, published in PNAS, suggests that abrupt transitions from dense forest coverage to savannah-like landscapes pose a significant risk to the ecosystem.
A new system, Coded Aperture Compressive Temporal Imaging (CACTI), uses AI to overcome traditional limitations in high-speed photography. The system achieves exceptional image quality while reducing data requirements, making it useful for studying transient physical processes.
A 150-day microcosm experiment simulated acid rain, weakening native microbial networks and creating space for invasive pathogens. The study found that surviving populations underwent major genomic remodeling, evolving into more persistent and virulent strains.
A novel acid-promoted radical substitution strategy achieves selective synthesis of m-phenylenediamine compounds from aromatic amines, offering a more efficient and regioselective approach than current methods. The reaction exhibits good substrate versatility and functional group compatibility.
The study reveals a relationship between X-ray luminosity and rotation velocity, with the accretion system changing during the faint phase. The height of the accretion column was found to change with the 10-year flux modulation.
Research finds that automatic patient outreach significantly increased the number of patients who completed advance care planning documentation. The study, published in Annals of Internal Medicine, suggests that health systems can implement automated mechanisms to promote advance care planning conversations and improve patient outcomes.
Single-crystal HfB2 nanorods exhibit enhanced mechanical properties, with a 4.1% increase in hardness and 37.6% improvement in fracture toughness. The nanorods also demonstrate excellent ablation resistance, impeding oxygen atom penetration and reducing mass ablation rates.
A study published in The BMJ found a 25% decline in diversity language in NIH grants from January 2024 to June 2025. Researchers analyzed 17,701 grants and found that words related to diversity, equity, and politics were deleted at a 10-fold higher rate in 2025.
Microplastics leak a complex mixture of dissolved organic chemicals that evolve over time, especially under sunlight. The study provides the most detailed molecular-level view to date of how this microplastic-derived dissolved organic matter forms and transforms in natural waters.
Researchers found that wildfires can convert chromium 3, a benign form in rocks and soil, into the carcinogenic chromium 6. Soils from summits contained high levels of chromium 6 when burned at temperatures above 750 F, which could taint groundwater for up to 2.5 years. The study highlights the need for better understanding of fire's i...
A new study found that rising temperatures are driving changes in polar bear DNA, which may help them adapt to increasingly challenging environments. The researchers discovered that genes related to heat-stress, aging, and metabolism are behaving differently in polar bears living in southeastern Greenland.
A new study found that calcium accumulation in breast arteries and its progression on mammograms can predict future cardiovascular disease. Women with more severe calcification and those whose calcification worsened over time had a higher risk of heart-related events, such as heart attack, stroke, and death.
A UBC Okanagan study found that microdosing psychedelics temporarily improves mood, creativity, and wellbeing, but these effects do not persist on non-dosing days. The study, tracking over 1,435 participants from 49 countries, suggests that microdosing may 'reactivate' or build upon prior effects of larger-dose psychedelic experiences.
A new blood biomarker, neurofilament light (NFL), has been shown to accurately predict the extent of brain damage after a cardiac arrest. This breakthrough discovery may transform care for patients in intensive care units, allowing for more informed decisions about their treatment.
A third of teenagers use AI companions for social interaction, with some reporting more satisfying conversations than humans. Experts caution against problematic chatbot use as a new environmental risk factor, particularly among vulnerable populations.
A new single-dose oral medication called zoliflodacin shows promise as a treatment for antibiotic-resistant gonorrhoea, with over 90% of infections cured at genital sites. The medication is well-tolerated and has the potential to improve global efforts to control drug-resistant gonorrhea infections.
A UBCO study found that resilience is shaped by supportive communities, not individual traits. Community-based strategies and place-based interventions are crucial for effective suicide prevention.
A study analyzing 1000 biomedical articles found that almost 1 in 5 'recent' references are at least 10 years old, suggesting the term is used more as a narrative device than a measure of time. Citation patterns varied across medical specialties, with some fields citing older references than others.
Research from University of Vermont reveals exposure to Canadian wildfire smoke worsened asthma symptoms in children in the US Northeast. The study found that smoke from hundreds of miles away affected children's health, highlighting growing health risks for the region as climate change fuels more smoke-filled summers.
The discovery of a 66-million-year-old tooth in North Dakota, USA, reveals that mosasaurs may have hunted in freshwater environments as well as seas. The analysis of isotopes in the tooth's enamel suggests that the mosasaur preyed on freshwater animals and lived in a river-like area formerly connected to an ancient sea.
A new study evaluates four microbial aerosol samplers and finds that membrane filtration produces the highest collection efficiency for particles at or below one micrometer. The study suggests that choosing the right sampler is crucial for accurate airborne pathogen detection.
The grant aims to increase individual screenings and change how health systems embed evidence-based screening practices into everyday operations. PA-CARES will work with trusted organizations in 28 counties with the lowest screening rates to implement effective screening options and facilitate timely linkage to care.
Muthu Wijesundara, a UT Arlington researcher, has been honored as a National Academy of Inventors fellow. He is recognized for his innovations in robotic exoskeletons and advanced medical devices, which aim to improve healthcare outcomes.
A Phase III trial has demonstrated the survival benefit of proton therapy compared to traditional radiation therapy for oropharyngeal cancer patients, with improved overall survival at five years. Proton therapy also resulted in reduced toxicities and feeding tube dependence, highlighting its potential as a standard treatment option.
A study published in the journal Children found that improving access to safe drinking water can reduce the odds of stunting by about 20%. The researchers analyzed data from over 3,500 children and found that clean water access had a stronger impact on child growth than sanitation.
A new species of roundworms, Diplolaimelloides woaabi, has been discovered in the Great Salt Lake, characterized by its unique features and potential role in the lake's ecosystem. The discovery raises questions about how the worms arrived in the lake and their adaptation to highly saline environments.
The study found that the investigational vaccine produced an immune response in 74% of participants and was safe and well-tolerated. A Phase 2 study is planned to evaluate the vaccine's efficacy, offering new hope for triple-negative breast cancer treatment.
Researchers have developed a nearly 100 times smaller device that can efficiently control lasers required for thousands of qubits, unlocking potential for larger quantum computers. The device uses microwave-frequency vibrations to manipulate laser light with extraordinary precision.
A new review evaluates biological strategies to improve the efficiency of photosynthesis, highlighting promising solutions such as engineering Rubisco enzyme and developing cooperative crops. The research aims to address global challenges in agriculture and ensure food security for the world's population.
A patient with refractory synovial sarcoma was the first in Arizona to receive TECELRA, a genetically modified autologous T cell immunotherapy. The treatment showed early signs of tumor shrinkage and has been shown to benefit over 40% of patients with similar cancer types.
Dr. Mintz brings exceptional clinical care, research, and education expertise to the role. He will lead transformative initiatives in perioperative operations, improving financial performance, employee satisfaction, quality, safety, and patient experience.
A prospective multicenter trial validated an improved method for predicting treatment benefits in hormone receptor-positive metastatic breast cancer with bone metastases. Metabolic change assessed by FDG-PET/CT accurately predicted progression-free survival as early as 12 weeks after treatment initiation.
CEMIP is associated with the breakdown of myelin, a protective sheath around nerve cells. Elevated levels of the enzyme inhibit myelin regeneration in people with multiple sclerosis. Researchers hope targeting CEMIP may promote central nervous system repair and slow disease progression.
James Schwob, a professor at Tufts University School of Medicine, has been named a fellow of the National Academy of Inventors. His research focuses on the mechanisms that regulate neural development using the peripheral olfactory system as an ideal model for neuroregeneration and therapeutic approach for age-related olfactory loss.
Researchers have discovered that jarosite selectively captures bromine under Mars-like conditions, offering insights into the Red Planet's aqueous past and halogen cycling. The study reveals a clear trend: bromine is strongly favored over chlorine for incorporation into jarosite, with specific temperature-dependent effects.
L. Jay Guo, University of Michigan professor, recognized for scalable nanopatterning technology enabling next-gen flexible electronics and structural color applications. His work has attracted interest from major companies like Samsung and Toyota.
A new study suggests that indoor lighting can strongly influence listeners' experiences while listening to music. The research found that warm white lights were most effective in evoking positive emotions, while blue lights had the least positive response. These findings have implications for improving well-being and mood regulation in...
Florida Atlantic University's College of Engineering has received a $600,379 grant to advance technology targeting harmful algal blooms in Florida's waterways. The project aims to develop novel 3D-printed adsorbent materials for efficient phosphate removal.
Researchers investigated how AI can aid clinicians in analyzing medical images and found that while AI improves diagnostic accuracy, it also requires careful consideration of explanations and trust levels. The study's findings highlight the importance of balancing ease of use with utility in designing AI systems for clinical applications.
Researchers at MIT have discovered a simple way to make carbon capture more efficient and affordable by adding a common chemical compound called tris to capture solutions. This innovation can stabilize the pH of the solution, allowing the system to absorb triple the amount of CO2 at relatively low temperatures.
Scientists have discovered a shape-shifting molecular valve in PANX1, a cellular gate that controls the flow of chemical messages. Researchers found that a common antimalarial drug can enhance or inhibit this gate's activity, paving the way for precision therapies.
Researchers identified various strategies to prevent and detect fraudulent responses, including outreach and recruitment plans, short screener surveys, and community-engaged methods. These approaches can help distinguish real from fake participants and mitigate the impact of fraud on injury and violence prevention studies.
A study published in Biological Psychiatry identifies a distinct immuno-inflammatory biomarker in the brain linked to immune system dysfunction and poorer response to standard treatments. The findings provide potential value for clinical prediction and precision therapies.
The CaliBaja Higher Education Consortium brings together institutions from California and Baja California to enhance student and faculty mobility, bolster research networks, and support a highly skilled binational workforce. The alliance aims to address shared challenges and opportunities in the region.
A new method has been developed to generate valid confidence intervals for problems involving data that vary across space, helping researchers trust the results of certain experiments. This work can be applied to fields like environmental science and epidemiology.
Researchers have developed a quantitative technique to determine peak shock pressures in enstatite chondrites using micro-X-ray diffraction. This non-destructive method unlocks transformative applications for high-throughput shock screening and asteroid collision forensics.
A new study from Columbia University's Mailman School of Public Health found that sexual minority individuals have a 7% higher odds of primary Cesarean birth compared to completely heterosexual participants. Disparities were especially pronounced when labor was induced, raising concerns about potential provider bias and unequal interve...
A $2.67 million gift from the estate of Dr. William A. Gibson will establish the Michael Conner Gibson Endowed Professorship in Psychology and the Michael Conner Gibson Research Endowment, accelerating UH's addiction research program.
UNCG will establish an extended reality center with HTC VIVE and Virtualware funding, driving innovative research and workforce development in the region. The center will offer a collaborative, group-based learning environment for students and industry partners to explore new immersive technologies.
American artist Adrien Segal has been awarded the Planetary Futures Public Art Residency at the SETI Institute for a two-year term. The residency aims to foster dialogue and inspire collective action through the connection of artistic practice with scientific discovery, particularly in climate research.
Researchers at the University of Colorado Boulder have designed a new material called Mesoporous Optically Clear Heat Insulator (MOCHI) that can improve energy efficiency in buildings. The material, which is almost completely transparent, traps air through tiny pores to block heat exchange.
A new study by University of Illinois researchers finds that extreme weather events can have wide-ranging effects on food production and manufacturing in the US. Climate shocks, such as droughts and floods, can reduce agricultural output and increase prices, affecting states that rely heavily on imports.
Early life adversity disrupts activity across multiple brain networks when threats are encountered later in life, according to a new study published in the Proceedings of the National Academy of Sciences. The study found that mice subjected to adversity in infancy showed abnormal brain activity in response to threats as adults.
MIT researchers developed a new fabrication method to stack multiple functional components on top of one existing circuit, reducing energy wasted during computation. The new approach enables the production of more energy-efficient electronics, boosting computation speed and reducing electricity consumption.
A study published in the Journal of Mammalogy found that raccoons in Forest Park in St. Louis avoid crossing roads, even when offered open food sources. The research used GPS collars and accelerometers to track animal movements and behavior across seasons, revealing cautious behaviors towards road crossings.
A recent study has identified five categories of psychiatric disorders that share similar genetic factors, including compulsive features, internalizing conditions, substance use disorders, neurodevelopmental conditions, and a category combining bipolar disorder and schizophrenia. The research suggests that these shared genetic factors ...
A study of 101 glioma cases reveals that one-third of patients develop permanent paralysis after surgery. High tumor grade, pre-operative motor deficits, and larger tumor volume are key predictors. The work underscores the importance of careful surgical planning to maximize survival while safeguarding motor function.
The ISSCR symposium highlights new clinical trial results and emerging technologies advancing PSC-derived cell therapies. Key findings include breakthrough approaches for treating drug-resistant epilepsy and geographic atrophy, as well as durable remission in type 1 diabetes.
A UCO study verifies acorns' high starch content, fatty acid profile similar to olive oil, and nutrient-rich compounds with antioxidant and anti-inflammatory activity. The research identifies diverse microbiomes associated with seeds influencing bitterness levels and paves the way for future domestication programs.
Researchers at Cornell University used optogenetics to boost large sharp-wave ripples in the brains of mice, improving their ability to remember new experiences. The technique showed promise in extending memory consolidation even in mice engineered to have cognitive deficits.
Jason McCarthy, a renowned biomedical researcher, has been promoted to professor at the Masonic Medical Research Institute. He has made significant contributions to medical research since joining the organization in 2018.
The PROTHOR study investigated the effects of different ventilation strategies during one-lung ventilation on postoperative pulmonary complications. The results showed that higher positive end-expiratory pressure (PEEP) and recruitment maneuvers led to better gas exchange, but negatively affected blood pressure. The choice of ventilati...
Research suggests that tropical smallholder farms in fragmented landscapes can maintain healthy pollinator populations and fruit production, contrary to expectations. The study's findings highlight the importance of ecological diversity in supporting wild pollinators.
A new analysis using COTSI data reveals that verifying fake accounts for use in the US and UK is almost as cheap as in Russia, while Japan and Australia have high prices due to SIM costs and photo ID rules. The average price of SMS verification for an online platform was $0.26 in the US and $0.10 in the UK.
Tumor-specific MHC-II expression is a critical driver of antitumor responses, modulating CD4⁺ T-cell priming, differentiation, and memory formation. This review highlights MHC-II as a promising biomarker and therapeutic target for next-generation cancer treatments.
Researchers have identified the enzyme N4BP2 as the key driver of chromothripsis, a process in which cancer cells rapidly evolve and become resistant to treatment. The study reveals that tumors with high N4BP2 expression exhibit significantly more chromothripsis and structural rearrangements.
Researchers developed an implantable and fully absorbable sensor film to detect circulatory disorders in intestinal anastomoses, enabling early detection of complications. The technology has the potential to prevent consequential damage and improve patient care.
A new study found significant disparities in Maryland's rural communities, with many cases of Alzheimer's disease remaining undiagnosed. The research highlights the impact of hospital accessibility and poverty rates on health outcomes, particularly for older populations.
A new study finds that untreated obstructive sleep apnea accelerates cardiovascular aging, leading to higher mortality rates. Researchers used a long-term mouse model to demonstrate the chronic physiological stress created by sleep apnea fundamentally alters cardiovascular structure and function.
Researchers have found that CAR T-cell therapy with cilta-cel leads to higher rates of complete remission and longer progression-free survival compared to ide-cel. Treatment success is linked to factors such as tumour burden, T-cell fitness, and systemic inflammation.
A team of astronomers used NASA's JWST to reveal an alien atmosphere in the ancient, ultra-hot super-Earth TOI-561 b. The planet's thick atmosphere is upending conventional wisdom about ultra-short-period planets, and its composition could be representative of planets that formed when the universe was relatively young.
Researchers developed a new tool, FibrilPaint combined with the FibrilRuler test, to measure the length of toxic Tau amyloid fibrils directly in solution. This 'molecular ruler' represents a major advance in understanding how these fibrils grow, break, and respond to potential drugs.
Scientists successfully introduce ferromagnetism into bismuth ferrite at room temperature through dual-cation substitution, enabling potential use in low-power memory devices. Negative thermal expansion is also observed, which could help solve problems caused by thermal expansion in electronic components.
Research from the University of Surrey discovers that small energy barriers in transistors make them more stable and reliable. The study reveals a novel 'multimodal transistor' design with two gate electrodes, enabling separate control of current injection and flow, which improves device performance.
MIT researchers have found a new way to create solid particles of highly concentrated antibodies, suspended in a solution, which can be injected using a standard syringe. This advance could make antibody treatments more convenient and accessible for patients, particularly older people with difficulty visiting hospitals.
Researchers argue that taxing housing purchases during economic booms and providing temporary subsidies on housing during recessions could help prevent the next housing crisis. The study found that this approach can lift house prices exactly when the system is at greatest risk, preventing fire sales and severe price collapses.
A recent study from Michigan State University found that narcissism is a universal trait with consistent patterns across cultures, contrary to popular beliefs in the United States. The study included over 45,000 participants from 53 countries and found that young adults and men are more narcissistic than older adults and women.
A new study uses high-resolution GHGSat satellite observations to estimate facility-level methane emissions from thousands of oil, gas, and coal facilities globally. The findings provide a more detailed picture of global inventories and offer insights for mitigation strategies.
Researchers at KTH Royal Institute of Technology found that liquid lead forms an ultrathin film on steel surfaces, driving rapid dissolution and corrosion. The study suggests combining different types of steel to achieve long-lasting protection for next-generation reactors.
Researchers discovered that beneficial fungi enhance plant resistance to disease by remodelling the plant cell membrane at pathogen infection sites. This transformation coincides with a significant reduction in pathogen colonisation and offers critical new insights into how plants coordinate defences in complex natural environments.
The Konrad Adenauer Synergy Research Project explores how the 1990s shaped today's international order, shedding light on humanitarian norms, geopolitical alignments, and global governance institutions. The project aims to inform decision-making and strengthen responses to global challenges.
The Erasmus Mundus Joint Master programme trains environmental engineers for a sustainable future through international mobility and collaboration. Students will spend two years studying in three countries and obtain multiple master's degrees upon completion.
A decade-long study found that cultured shellfish distribution determines spatial hotspots and seasonal peaks of shorebirds along China's coast. The research suggests managed mariculture is a better solution to food security for migratory bird protection than imposing a ban.
Researchers created a reference brain by merging 40 ant brains, revealing surprising variations in brain size and a distinct tilt in higher-order processing regions. The study provides new insights into the neuroscience of individuality within animal societies.
Scientists at Lund University have tracked migratory red-backed shrikes using new data loggers, showing precise schedules and minimal variation between individuals. The study provides insight into genetics influencing small bird migrations across continents.
The emergence of A(H3N2) subclade K viruses in Australia and New Zealand extended their influenza seasons, with Australia experiencing a record-breaking season. The viruses were likely imported from the US and accounted for half of Australian viruses and over two-thirds of New Zealand viruses.
Researchers at Harvard University have discovered that cycads heat up their reproductive organs to attract beetle pollinators, who possess infrared sensors to detect these signals. The study found that all 17 cycad species followed a circadian pattern, with male cones heating first and females cooling down before warming up again.
Researchers discovered that bridgmanite acts like a microscopic 'water container', allowing early Earth to retain substantial amounts of water in the mantle as it solidified. This retained water played a crucial role in transforming the planet from an inferno into a habitable world.
Researchers discovered iron oxide polymorphs' effect on organophosphate ester pollutants' degradation. The study found that the crystalline phase determines OPE breakdown, offering insight into environmental fate and risks of plastic-derived contaminants.
A recent Science study analyzing seismic data reveals a series of eastward-propagating M>5 events along the Main Marmara Fault over the last ~15 years. This finding highlights the need for continuous monitoring to assess the potential impact of a large quake on Istanbul's 18 million inhabitants.
A new study reveals that factors present in aged blood can accelerate the accumulation of amyloid proteins and influence behavior in an experimental mouse model of Alzheimer's. The study found more than 250 differentially expressed proteins linked to synaptic functions, endocannabinoid signaling, and calcium channels.
A new study reveals that ammonia-oxidizing archaea rely on urea as a nitrogen source, enabling them to flourish in open ocean waters. This discovery challenges existing understanding of nitrification rates and highlights the crucial role of urea in sustaining ocean productivity.
A study by Raedeh Basiri found associations between dietary patterns, glycemic status, diabetes control, and sleep outcomes. Individuals with diabetes or prediabetes were more likely to have trouble sleeping and experience abnormal sleep duration compared to those without these conditions.
New research reveals the structure of matter surrounding supermassive black holes has changed over cosmic time, challenging a fundamental assumption about their behavior. The study combines new X-ray observations to explore the relation between X-ray and ultraviolet light intensity of an unprecedentedly large sample of quasars.
Plants have evolved thermogenic strategies to attract pollinators, including generating heat through cellular respiration. Cycads rely on specialized beetle pollinators and exhibit daily bursts of infrared radiation in the afternoon and early evening, which is sufficient to attract these insects.
A new index tracks the price of fake-account text verifications, revealing price spikes around elections and market trends that reflect national telecom costs. The findings highlight the economics underlying the online manipulation economy and suggest potential points of intervention to curb mass account fabrication.
A new study finds that warming, humidification, and rising nitrogen deposition can substantially amplify N₂O emissions from steppe ecosystems. The Eurasian steppe is a significant source of global N₂O emissions, with grasslands contributing nearly one-third of global emissions.
A new study suggests that a simple ECG reading from a smartwatch can accurately estimate a person's age, potentially offering a secure alternative to facial recognition or ID checks. The method achieved an average error of just under three years and accuracy consistently reached between 93 and 96%.
Researchers at the University of Jyväskylä have discovered a simple method to control which type of helix forms in artificial systems by adjusting the order of charged and neutral units. This breakthrough could lead to new adaptive materials and devices, including water purification applications.
A new study found that both EBOV and MARV are capable of infecting human gut epithelial cells and disrupting fluid secretion, mirroring severe symptoms. The researchers developed a mini-gut model using induced pluripotent stem cells and discovered key signaling pathways involved in ion and fluid transport.
Lori Lerner, a BU researcher, has received the Distinguished Contribution Award from the American Urological Association (AUA) for her work on benign prostatic hyperplasia (BPH). She has spent over two decades developing responsible surgical approaches and advocating for patient-centered care.
The European Alliance of Associations for Rheumatology (EULAR) has introduced three overarching principles and 11 points to consider for assessing disease activity in AOSD. The guidelines emphasize the importance of adopting a valid, reliable, and easily transferable definition of disease activity, which includes fever, skin rash, arth...
Researchers at HIPS have fully elucidated the biosynthetic pathway of biphenomycins, a potent antibiotic family against Gram-positive pathogens. They can now produce sufficient quantities and create new variants with improved pharmaceutical properties to combat drug-resistant S. aureus infections.
A new study found that wood warblers have borrowed color-related genes from neighboring species, leading to the evolution of diverse plumage colors. This gene exchange, known as introgression, occurred across multiple genera and is believed to have played a role in the group's rapid diversification.
Raghuraman Kannan and Henry Nguyen, University of Missouri professors, have been elected National Academy of Inventors (NAI) Fellows. They were selected for creating or facilitating inventions that have had a tangible impact on society, with over 5,300 U.S. patents between them.
A study by the University Hospital Bonn reveals that asthma immune cells have a special antioxidant protection mechanism to survive in an environment that should damage them. Disrupting this mechanism leads to reduced allergic inflammation in mouse models.
Researchers have made significant breakthroughs in poly(2,5-bis(3-alkylthiophen-2-yl)thieno[3,2-b]thiophene) (PBTTT), a liquid-crystalline conjugated polymer that has shown record figure of merit of 1.28 at 368 K
Astronomers at Northwestern University have directly imaged a Tatooine-like exoplanet orbiting two suns, revealing unique insights into how planets form around multiple stars. The discovery provides an unprecedented look at the complex dynamics of binary systems and offers new opportunities to test theories of planet formation.
A multicenter study found that higher-intensity rehabilitation in the ICU is linked to faster recovery and lower risk of delayed recovery for critically ill patients on mechanical ventilation. Purposeful mobilization preserves muscle strength and function, supporting faster return to independence.
A new study found a significant rise in ADHD stimulant prescriptions in Ontario, with a 157% increase from 2015 to 2023. The study calls for better clinical guidance to ensure medications are prescribed appropriately and prevent adverse health effects.
Researchers summarize advances in multi-target therapies addressing Alzheimer's disease pathology, including Amyloid-beta, tau, neurodegeneration, and cerebrovascular injury. Despite promising preclinical evidence, single-target strategies have shown limited efficacy in clinical trials.
Researchers identify spatial characteristics of initial errors triggering predictability barriers in IOD events, affecting summer weather forecasts. The study provides insights into dynamical mechanisms and sensitive regions for targeted observations to improve IOD event predictions.
A new study reveals that rapid temperature fluctuations have intensified under global warming, posing significant health risks. The research defines these events as occurring when the temperature difference between two consecutive days exceeds historical records, leading to more frequent and sharp swings between temperature extremes.
The PerMiCCion consortium is studying the microbiome to develop personalized prevention and treatment strategies for early-onset colorectal cancer. They identified a characteristic 'oncogenic microbiome' that promotes inflammation and influences immune response.
Approximately one-third of US adults met criteria for metabolic syndrome in 2023, with no significant change in prevalence between 2013 and 2023. Triglyceride levels demonstrated a modest increase over the past decade.
A new dataset and model improve the efficiency of machine-learning interatomic potentials and their applicability to different chemical elements and material classes. The PET-MAD model uses a compact and denser dataset of 95,595 structures and an original neural network architecture, achieving robust simulations with minimal fine-tuning.
Researchers have identified a potential biomarker for targeted psoriasis therapy by discovering the link between fat metabolism and skin inflammation. FABP5 drives ferroptosis, amplifying inflammatory processes in the skin, which can be blocked to improve skin changes associated with psoriasis.
Researchers found that killer whales and Pacific white-sided dolphins cooperate while hunting salmon in British Columbia waters. The orcas use dolphin echolocation to locate Chinook salmon, which the dolphins then scavenge for food scraps after the orcas eat their share.
An analysis of popular song lyrics from 1973 to 2023 found that they have become simpler, more negative, and contain more stress-related words. The study suggests that music is used as a form of escapism during stressful periods, leading to a shift towards more positive and complex lyrics.
A repeated cross-sectional study found a significant increase in stimulant prescribing for ADHD, with the largest acceleration observed among female adolescents and young adults aged 18 to 64. The study's findings are consistent with prior research but provide new insights into population-level trends.
Leading synthetic biologists share hard-won lessons from their decade-long quest to build the world's first synthetic eukaryotic genome. The insights could accelerate development of climate-resilient crops and custom-built cell factories.
The Asia Pacific Regional Audit highlights key trends, gaps, and opportunities in 22 countries and regions. The audit reveals a steep rise in fracture rates due to poor bone health and an ageing population, with China, Malaysia, and Australia experiencing significant increases.
China's urban forests have grown significantly since 2010, increasing by 16.07 × 10^4 km² and storing up to 522.7 Tg C by 2060. The carbon sequestration rate peaked in 2015-2020, with a range of 1.92-22.8 Tg C/year.
Researchers have developed a novel cathode material that achieves high energy density and long cycle life in rechargeable aluminum-ion batteries. The sulfur-heterocyclic polymer cathode outperforms traditional graphite cathodes, demonstrating exceptional durability and low-temperature stability.
A new study found that neural inhibition and balanced activity in a specific brain area are necessary for recognition memory. The research suggests that too little or too much neural inhibition in the hippocampus can disrupt object recognition memory.
A new study found that annual ADHD prescription rates increased by 157 percent in Ontario from 2015 to 2023, with significant increases in females and younger age groups. The authors suggest a potential rise in true cases of ADHD, improved diagnosis, or misdiagnosis as contributing factors.
The study reveals the exceptional versatility of magnetic Weyl semimetals in chiral control, enabling real-time and reversible modulation by external fields. This property establishes them as a more adaptable platform for future quantum devices based on chiral degrees of freedom.
Researchers develop a strategy that delivers record FF of 80.1% and maintains high efficiency even at thin active-layer thickness. The design offers a cost-effective pathway to high-efficiency, thick-film organic solar cells.
A study of 800 young people found that around one in ten boys developed computer game addiction, characterized by strong involvement and negative consequences. Parents are advised to address gaming habits early on.
Researchers discovered that a missing piece of myelin in nerve cells slows signal transmission to the thalamus, disrupting communication loops and cognitive tasks. This finding sheds light on symptoms associated with grey matter lesions in MS.
Transformers and graph neural networks integrated with multiple pre-training tasks improve drug discovery accuracy. Molecule captions facilitate collaboration between large language models and drug discovery.
Researchers identified multiple well-supported clades corresponding to known genera and detected previously unrecognized lineages. They described two new genera and three new species, including Proxiconiothyrium yunnanense and Periconia longibrachiatum, expanding knowledge of Pleosporales diversity.
This study investigates how environmental variability and human migration influence the evolution of cooperation among humans. Simulation results reveal that cooperation is more likely to evolve when these factors are sufficiently high, hindering non-cooperative groups and encouraging cooperative groups.
A recent study found that omitting sentinel lymph node biopsy (SLNB) in clinically node-negative, HR-positive, HER2-negative early-stage breast cancer patients did not compromise regional control or survival after a median five years of follow-up. The recurrence of the cancer in the lymph nodes surrounding the primary tumor was observe...
Philip R. Troyk, director of the Pritzker Institute of Biomedical Science and Engineering at Illinois Tech, has been elected as a Fellow of the National Academy of Inventors for his groundbreaking work on neuroprosthetic devices, including an implanted cortical visual prosthesis that provides artificial vision to individuals with profo...
The study found that upper and lower tooth germs exhibit distinct transcriptomic profiles at the cap stage, with maxillary-enriched genes associated with morphogenesis and lower-enriched genes linked to mineralization. The researchers also validated key findings using RT-qPCR and immunofluorescence staining.
A recent study published in Neuropsychopharmacology found that rats with higher natural stress levels are more likely to self-administer cannabis. The study also identified links between stress hormone levels and cognitive flexibility, suggesting potential early markers for problematic drug use patterns.
Researchers at TUM have discovered that deuterons and antideuterons are formed through the decay of highly energetic particle states, releasing protons and neutrons necessary for their formation. This finding improves models of particle formation and could provide clues about dark matter.
Researchers detect strong evidence for an atmosphere on ultra-hot super-Earth TOI-561 b, challenging the idea that small planets can't sustain atmospheres. The planet's unusually low density is explained by a thick volatile-rich atmosphere that circulates heat and cools the nightside.
A new study presents a comprehensive multi-scale computational framework capable of predicting the mechanical responses of Fe–Cr–Al alloys. The framework integrates molecular dynamics, phase-field simulations, and finite element modelling to simulate solid-solution effects and processing-induced microstructural evolution.
Researchers developed a precision magnetometer based on magneto-optic material that changes optical properties in response to a magnetic field. The device can detect magnetic fields comparable to those of high-performance cryogenic magnetometers, but with minimal size, weight and power consumption.
Research from Florida Atlantic University strengthens evidence that alcohol consumption increases cancer risk, particularly for breast, colorectal, and liver cancers. Higher intake and specific groups, such as African Americans and those with obesity or diabetes, are found to be more vulnerable to the risks.
Insilico Medicine and Taigen Biotechnology collaborate to develop and commercialize ISM4808, an AI-driven PHD inhibitor for treating anemia of Chronic Kidney Disease (CKD). The partnership grants TaiGen exclusive rights for further development, commercialization, and sub-licensing in the Greater China area.
Researchers develop shape-morphing device to overcome pancreatic tumor microenvironment barriers, achieving remarkable therapeutic efficacy in mouse models. The device delivers low-intensity photostimulation that precisely targets cancer cells while preserving normal tissue.
A phase II clinical trial found that preoperative radiation improved T-cell infiltration and treatment responses in hormone receptor-positive, HER2-negative breast cancer patients. Radiation doses of 24 Gy showed the greatest increase in TCI and tumor clearance, suggesting a potential new strategy for immunotherapy.
The study reports a novel strategy for highly efficient photocatalytic synthesis of hydrogen peroxide (H2O2) from neutral water. A Pd-CNO2 coordination structure is integrated into a keto-form anthraquinone-based covalent organic framework, developing a highly efficient single-atom catalyst.
The National Academy of Inventors has elected 169 U.S. distinguished academic inventors and 16 International Fellows to the 2025 cohort, holding over 5,300 U.S. patents. This year's class represents 127 universities, government agencies, and research institutions across 40 states.
A recent study found that preoperative breast MRI did not significantly impact five-year recurrence rates or overall survival in patients with stage 1 or 2, hormone receptor-negative breast cancer. The trial involved 319 patients and showed similar results between those who underwent MRI and those who did not.
Dr. Liu's work uses genome and RNA sequencing to improve diagnosis and treatment of rare genetic diseases, benefiting thousands of patients. He has established whole-genome and RNA sequencing as clinically approved tests, enabling individualized medicine and personalized treatment.
A study by Linköping University found that right-leaning people are more susceptible to conspiracy theories and misinformation, while those on the left are less affected. The researchers suggest exposure, psychological factors, and anti-democratic values may contribute to this phenomenon.
Researchers from Okayama University and Tohoku University have identified a promising way to breach the physical and biochemical barrier created by fibrosis in pancreatic cancer. By blocking collagen signaling through DDR1, they improve drug delivery and enhance treatment response.
Dr. Bilal Akin has been recognized for his groundbreaking research on sustainable and high-efficiency energy conversion systems for electric vehicles and industrial automation. His innovative contributions have enabled early warnings and enhanced system safety, shaping the future of energy and transportation.
Dr. Fan Zhang, a pioneering theoretical physicist, has made groundbreaking discoveries in quantum matter and topological physics. His research has transformed our understanding of electronic correlations and topology, inspiring experimental breakthroughs worldwide.
Dr. Yunsun Nam's groundbreaking research on RNA-protein interactions reveals key insights for gene regulation, cancer biology, and RNA-based therapeutics. Her work uncovers molecular rules governing specificity between proteins and RNAs, shedding light on novel mechanisms linking dysregulated RNA methylation to cancer.
Insilico Medicine's AI platforms enable discovery of a novel, potent, selective, and orally administered DGKα inhibitor that restores T cell function and overcomes checkpoint resistance. The compound exhibits strong combination activity with anti–PD-1 and anti–CTLA-4 therapies in preclinical studies.
Researchers at Cold Spring Harbor Laboratory have devised a new approach to stimulate cell growth and repair in the intestine using CAR T-cell therapy. This therapy has shown promising results in improving gut health in both young and old mice, with significant reductions in inflammation and improved nutrient absorption.
Dr. Yue Hu has developed a system that applies reinforcement learning to optimize real-time industrial processes in the energy sector, delivering $20 million in annual savings for bp. Her work also enables transfer of expert knowledge to younger engineers through re-playable simulations.
A new study by University of Rochester finance professors argues that socially responsible investors' capital can inadvertently create incentives for firms to postpone green reforms. The researchers suggest public commitments and binding principles of responsible investing could overcome this issue, making impact investing more effective.
Valvular heart disease is prevalent in cancer patients, with severe cases associated with increased mortality. Interventions for valvular heart disease significantly improved survival rates among those who received treatment.
Cuffless devices, such as smartwatches and patches, have shown promise in measuring blood pressure but require standardized validation for medical decision-making. The American Heart Association has outlined key limitations and recommended further research to establish their accuracy.
A new study by researchers at TU Graz and the Know Center shows that AI-powered recommender systems can perpetuate unfairness if not designed with human decision-making in mind. The study proposes a multi-stakeholder approach, involving service providers, municipalities, and local residents, to ensure fairness and transparency.
An AI-based imaging tool predicts reduced coronary blood flow, measured with CT-derived fractional flow reserve (FFR-CT), to diagnose angina and predict future cardiovascular events. The study shows that FFR-CT adds incremental value to traditional cardiovascular risk factors in predicting cardiovascular outcomes.
Daily scans taken during prostate cancer radiotherapy can identify changes linked to future rectal bleeding as early as one week into treatment. This allows doctors to adapt radiotherapy to limit side effects while maintaining cancer control.
A team of researchers has reconstructed how the cerebellum establishes its connections with the rest of the brain during earliest stages of life. The work describes the phases in which these neural connections emerge, expand, and are refined, offering a comprehensive map of cerebellar projections across the mouse brain.
A study found that a global pandemic is quietly wiping out sea urchins around the world, with populations nearing local extinction in the Canary Islands. The 2022-2023 mass mortality event affected the entire population of the species across the archipelago, causing a 74% decrease in La Palma and a 99.7% decrease in Tenerife.