A study found that hospitals sold to REITs were more than five times as likely to close or file for bankruptcy compared to similar hospitals. The researchers analyzed nearly 20 years of data and found no immediate improvements in finances or quality, but long-term harms, including increased risk of closure or bankruptcy.
The Cherenkov Telescope Array Observatory has begun construction on its southern site in Chile, paving the way for the world's largest and most powerful observatory for gamma-ray astronomy. The CTAO will focus on understanding relativistic cosmic particles, probing extreme environments, and searching for dark matter.
A new study by Case Western Reserve University and University Hospitals found that financial factors are the strongest predictors of participation in cancer research studies. The researchers recommend addressing practical challenges like transportation, childcare, and lost wages to make clinical trials more inclusive.
The ESMT Berlin study analyzed 90 studies with over 16,000 participants to conclude that those who make the first offer and come well-prepared tend to achieve better outcomes. Higher first offers often lead to better final outcomes, but there are limits to this approach, particularly when demands are very high or unrealistic.
The ToFuel EU project develops a new biorefinery concept to convert tomato residues into sustainable aviation fuel, fertilizer, animal feed, and nutritional oil. The process aims to be waste-free, climate-neutral, and economically competitive.
Researchers developed a genetically informed dynamic species distribution model to reconstruct the distributional history of wild Piper nigrum from 21,000 years ago. The model identified glacial refugia and patterns of range contraction, expansion, and fragmentation following the Last Glacial Maximum.
Researchers have developed a spray-on polymer coating that can be sprayed directly onto plant leaves to protect against harmful bacterial infections and survive drought. The coating works by disrupting bacterial cell membranes, reducing water loss and inducing molecular-level stress response mechanisms.
Researchers developed a new compact Raman imaging system that can differentiate between tumor and normal tissue, offering a promising route to earlier cancer detection. The system uses special SERS nanoparticles to detect faint signals from tumor markers, highlighting spots likely to contain tumor tissue.
Research published by the American Psychological Association suggests that swearing can improve physical performance by helping individuals feel focused, confident, and less distracted. Participants who swore during a chair pushup task were able to support their body weight significantly longer than those who repeated a neutral word.
Dr. Conacci-Sorrell's research reveals how cancer cells harness nutrients to drive growth and creates targeted strategies to suppress untreatable cancers. Her work focuses on nutrient utilization and protein synthesis, uncovering potential therapeutic targets in various types of tumors.
Researchers from Tokyo University of Science developed an efficient strategy to synthesize PROTACs using a three-step click chemistry method. This approach rapidly assembles functional molecules, enabling the easy introduction of ligand components and probe functionalities.
A global study evaluates whether a new early-warning platform can support earlier interventions against dengue outbreaks. The E-Dengue platform, tailored for district-level decision-making, has been integrated into Vietnam's routine dengue surveillance and will be tested in a large cluster randomized controlled trial.
A decline in churchgoing among middle-aged, less educated white Americans is linked to increased mortality rates from drug overdoses, suicide, and alcoholic liver disease. The study found that states with the largest declines in churchgoing experienced larger increases in deaths of despair, starting years before the opioid crisis began.
In a new study, Northwestern scientists identified a previously unknown toxic sub-species of amyloid beta oligomers that drive brain changes in Alzheimer's disease. NU-9 decreased this toxin and reduced damage in a mouse model, suggesting it could prevent or delay the cascade of toxic events that destroy neurons.
Altermagnets exhibit unique magnetic structure due to unconventional symmetries, enabling spin-polarized electron currents. A new method reveals this hidden structure using circularly polarized light and resonant photoelectron diffraction.
The University of Texas at San Antonio has received a $7 million gift commitment from Ed and Linda Whitacre to advance research, student success, and athletics. The gift will fuel groundbreaking discovery in metabolic health and strengthen the institution's role in improving health outcomes for South Texans.
Researchers from Chonnam National University propose a novel delay-compensated control strategy that eliminates current sensors in boost PFC converters. This simplifies circuitry, reduces hardware failure points, and enhances power quality, leading to smaller, more efficient, and cost-effective power adapters.
A new study found that genetic communities in rats are shaped by their social partners' genes. Researchers identified three gene-microbe associations, including one linked to bacteria that feed on sugar molecules added to mucus.
Researchers have identified DNA switches that control how brain cells called astrocytes work, which are known to play a role in Alzheimer's disease. The study used CRISPRi technology and single-cell RNA sequencing to test nearly 1000 potential switches, finding that about 150 of them controlled genes implicated in Alzheimer's disease.
Researchers developed a scientifically validated personality test framework for AI chatbots, showing that larger models accurately emulated human traits and could be reliably shaped through prompts. The study raises concerns about AI safety and ethics, highlighting the need for regulation to prevent misuse.
A comprehensive review highlights the urgent need to transform unsustainable food systems, which drive both obesity and environmental harms. The authors recommend subsidies for healthy foods, taxes on unhealthy products, and restrictions on aggressive marketing to address these twin crises.
A landmark study published in Nature Metabolism reveals how citrin deficiency, a rare genetic disorder, triggers fat buildup in the liver despite being lean. The research also discovers a hormone that reduces cravings for sweets and alcohol, providing new therapeutic targets for MASLD and fatty liver disease.
A new study found that real estate investment trust (REIT)-acquired U.S. hospitals were more likely to close or go bankrupt compared to non-REIT-acquired hospitals. Despite no impact on quality of care, REIT acquisition led to significant financial strain.
Osaka Medical and Pharmaceutical University researchers have captured time-resolved structures of an enzyme during its catalytic cycle, revealing dynamics that are nearly impossible to observe by other methods. This breakthrough offers valuable insights into enzyme function and potential applications in molecular design of novel enzymes.
A recent rat study found that an individual's genes can shape their own gut microbiome as well as the microbiomes of those they live with. The research identified three new gene-microbe links and demonstrates how genetic influences can ripple through social groups via shared microbes
Researchers found that the skin relies on TRPM8 sensor for cold detection, while internal organs primarily use TRPA1 sensor. This difference explains variations in external and internal cold perception, and has implications for understanding thermal homeostasis and pathologies related to cold sensitivity.
Researchers at Kobe University developed a method to preserve iPS cells directly in their culture dishes using D-proline as a cryoprotectant. This allows for easy automation of the process, reducing costs and increasing efficiency in regenerative medicine and drug discovery research. The breakthrough enables the direct freezing, thawin...
A new computational framework allows researchers to recreate different evolutionary trees by changing the structure of the world and tasks AI agents complete. The framework showcases how tasks drove eye evolution in agents, with navigation tasks leading to compound eyes and object discrimination driving camera-type eyes.
A team of researchers developed a comprehensive framework for electric vehicle (EV) range prediction and intelligent management using real-world data. The framework, which incorporates driving behavior, ambient temperature, and battery State of Health, improves prediction accuracy by up to 30%.
A virtual diet and exercise program has been shown to reduce treatment side effects and increase treatment retention, according to a Sylvester study presented at ASH 2025. Lifestyle interventions can also help patients with blood cancers such as MDS and large B-cell lymphoma receive more effective and less toxic treatments.
Conservation organizations are using eBird data to select priority species, manage habitat for waterfowl, identify important bird areas, and monitor populations at regional scales. The study demonstrates how eBird data products help fill critical information gaps and support conservation planning across many Joint Ventures.
Researchers at the University Hospital Bonn and international collaborators have deciphered the genetic instructions for building MOG antibodies. The study reveals that these antibodies contribute to the destruction of the protective myelin layer in the brain, leading to inflammation in the central nervous system.
A new study finds that China's Climate Policy Uncertainty (CPU) amplifies risk contribution volatility in Energy and Materials sectors during moderate market declines, but reduces it in Consumer Staples and Finance. However, during extreme market crashes, CPU increases risk volatility across all sectors except Healthcare.
This study uses a novel approach to capture group-level risk synchronisation in Chinese stock sectors, revealing how multi-sector co-movements can accelerate contagion and create systemic threats. By identifying crisis-specific resonance clusters and tracking resilience in real-time, the research provides a more precise tool for monito...
This study applies Physics-Informed Neural Networks (PINNs) and Extreme Learning Machines to solve complex option pricing problems under stochastic volatility. The research enables accurate pricing of American-style options for both equity and real estate index derivatives, addressing a significant challenge in quantitative finance.
A new AI framework uses a pre-trained viral protein language model to predict the adaptation risk of unknown viruses. The framework, called GIVAL, achieves high accuracy and robustness even with incomplete data, providing critical support for early warning and proactive prevention and control of viral infectious diseases.
Dr. Tom McClelland from the University of Cambridge believes that our current evidence is insufficient to determine whether artificial intelligence has achieved consciousness. He suggests that sentience, which involves positive and negative feelings, is a more critical factor in making AI ethically significant.
A small analysis found AI-generated images of doctors exaggerate and reinforce existing stereotypes on sex, gender, race, and ethnicity. This contradicts recent medical workforce statistics, which show a more diverse range of doctors in the UK and US.
A comprehensive review reveals that antibiotic resistance genes are ancient features of microbial life shaped by millions of years of evolution. Human activities such as agriculture, wastewater discharge, and global trade are accelerating the spread of these genes into disease-causing bacteria.
Researchers from the University of Modena and Reggio Emilia have developed a life cycle-verified roadmap to reduce greenhouse gas emissions in laser powder bed fusion. The study provides a tiered, cumulative action plan that factories can adopt incrementally, making measurable progress towards sustainability.
A study found that the week after the autumn clock change is associated with a reduction in demand for NHS services for anxiety, cardiovascular disease, depression, and psychiatric conditions. However, there is little evidence to suggest that the spring clock change has any short-term effect on health conditions.
A new study found that a pre-school health programme did not improve children's calorie intake or overall physical activity levels in nursery settings. The research suggests that policy-level and statutory changes are more effective in improving young children's diet and physical activity, highlighting the need for policy changes.
Western US faces a 'fire deficit' with 74% of areas behind on annual burns, requiring 3.8 million hectares of forest to burn each year over decade. Strategies like prescribed burns and managed wildfire use can help address the issue.
Experts warn that nicotine-containing products, including vapes, heated tobacco, and shisha, cause cardiovascular damage regardless of delivery system. The report highlights a rapid rise in youth addiction fueled by flavours and social media marketing.
Researchers developed an engineered antibody that outsmarts cytomegalovirus by avoiding its immune evasion strategies and activating immune cells to attack infected cells. This breakthrough could lead to safer and more effective treatments for vulnerable populations.
A new study from Kyoto University has identified a one-component superconducting state in strontium ruthenate, defying earlier predictions. The researchers developed a technique to apply shear strain to extremely thin crystals, finding that it had virtually no effect on the superconducting temperature.
Playing soothing live music in NICUs helps babies lower heart rate and respiratory rate while increasing feeding volume. Music sessions also provide a moment's respite for parents, allowing them to bond with their baby.
Researchers developed three process designs that capture higher value hydrocarbons during LNG regasification using seawater, with one configuration delivering strong economic performance. The study also highlights environmental advantages by reducing carbon dioxide emissions and improving overall efficiency.
A new study from the University of East Anglia finds that AI tools excel at speed and clarity, but human translators remain crucial for tone, cultural nuance, and natural sound. Generative AI can handle parts of video translation, but consumers still notice when something feels off.
Researchers in Illinois used public genebanks and shared data to accelerate corn quality research, identifying genetic regions influencing kernel composition traits. By combining near-infrared spectroscopy and genomic data, the team found well-known and previously unreported genomic regions associated with key kernel composition traits.
A new study from Columbia University Mailman School of Public Health reveals that young adults in the New York City area use multiple forms of cannabis, including vapes, edibles, and topicals. The research also shows that both vaped and smoked cannabis use have increased over time, with more participants initiating use than quitting.
Researchers discovered that SAR11 marine bacteria are organized into stable, ecologically distinct groups, adapted to specific environments such as coastal and open ocean. These findings provide new insights into the global ocean's life-support system and climate reactions to threats like pollution and ocean warming.
The American Museum of Natural History has discovered over 70 new species in 2025, showcasing the diversity of life on Earth. The discoveries include fruit flies, tiny mouse opossums, feathered dinosaurs and a newly identified mineral.
Researchers at the University of Oklahoma and West Virginia University are studying concept flavored cigarillos to determine their potential for addiction. The study aims to inform the FDA's impending flavor ban on cigar products, which could have wider-reaching implications for e-cigarettes and tobacco-free nicotine pouches.
Trigeminal neuralgia is a debilitating condition causing sudden, severe electric shock-like pain in the face. University Hospitals has successfully treated two initial patients with the OneRF Trigeminal Nerve Ablation System, providing complete pain relief without complications. The minimally-invasive procedure uses radiofrequency ener...
Researchers at Dartmouth's Geisel School of Medicine are conducting the first-ever multisite clinical trial to evaluate long-acting medication in treating opioid use disorder among adolescents. The study aims to establish guidelines for clinical care and understand what best practices are for treating adolescent opioid disorder.
Researchers at USF Health are developing new opioid compounds that provide pain relief without deadly side effects. The team's latest study uncovers new ways that opioid receptors work, offering hope for a better understanding of how to drug them and treat human health and disease.
The study analyzed 785,881 total posts from 513 members of the 117th Congress, identifying 12,274 gun-related posts using keyword-based filtering. Democrats respond directly to shooting events within 48 hours, while Republicans show no such response.
A new study found that deep underwater earthquakes can spur massive phytoplankton blooms at the ocean surface. Phytoplankton are microscopic, plant-like organisms that float in upper ocean layers and serve as the foundation of the oceanic food chain.
A recent study found that high doses of rifampicin do not improve survival rates among adults with tuberculous meningitis. The researchers are now exploring alternative treatments targeting inflammation in the brain membranes and investigating TNF inhibitors as potential therapies.