Researchers at UC San Diego used new airborne lidar to map cliff erosion and retreat, finding that change was highly uneven along the California coast. Hotspots were identified in Central and Northern California, with some areas experiencing retreat rates exceeding 70 feet per year.
A new study has provided important pharmacokinetic and safety data to guide dolutegravir dosing in newborns, supporting the FDA approval of the HIV drug for treatment from birth. The study found that dolutegravir achieves levels comparable to those in older children and adults, and is generally well-tolerated.
Researchers found that adding emotion management skills to family-based weight treatment helped teens regain less weight and report less emotional eating. The study, published in the Journal of the American Medical Association, suggests that addressing emotional factors can make behavioral treatment more durable.
Researchers from UC San Diego will join a national effort to accelerate the search for treatments for Alzheimer’s disease. The platform trial will test multiple combinations of natural products, repurposed FDA-approved drugs, and other potential therapies simultaneously using blood-based biomarkers.
A study by UC San Diego researchers found that macaques exposed to a deadly disease outbreak became more wary of contaminated food, suggesting that pathogen-avoidance behavior can be shaped by experience. The findings provide new insight into the behavioral immune system and its evolutionary roots.
A national study found that young adults were more likely to use high-nicotine e-cigarettes and experience increased nicotine dependence. By 2022, nearly half of young adults who vaped daily used e-cigarettes containing at least 4% nicotine.
Climate change is already affecting California's economy, with rising costs in health and labor, and disruptions in one sector raising costs in others. The report highlights the most vulnerable populations, including low-income households, outdoor workers, and rural communities, who face disproportionate economic burdens.
Researchers have made a breakthrough in understanding learned movements by activating just 20 brain cells, using advanced optical methods and neuron recording and stimulation techniques. The study, published in Nature, reveals that brief stimulation of these 20 neurons can trigger larger patterns of brain activity associated with a lea...
A new analysis of nearly half a million cells from dozens of pancreatic tumors reveals how tumor evolution, subtype transitions, and microenvironment interactions shape the disease. Genetic reconfiguration within a tumor enables cancer cells to transition between subtypes, making them more vulnerable to immune attack.
Engineers at the University of California San Diego developed a fluorine-free battery binder that simplifies manufacturing and recycling without sacrificing performance. The new binder performs just as well as conventional lithium-ion batteries and enables easier recycling by dissolving in water.
A new study published in Science found that the viscosity of marine snow plays a crucial role in transporting carbon to the deep ocean. Gooey marine snow can shuttle more than six times the carbon to the deep ocean than less viscous particles, making it a key factor in the carbon cycle.
Researchers discovered the genetic modification that gave butterflies their visual advantage, adding a photoreceptor to every unit of their compound eye. The brain adapted quickly to the new input, with no further genetic change needed, allowing butterflies to see more colors in flowers and locate nectar and potential mates.
Researchers at the University of California San Diego developed a new method to grow perovskite crystals with fewer defects, leading to higher efficiency and durability in solar cells and LEDs. The temporary melting liquid, called a eutectic, helps to neutralize electronic defects and produce larger, more uniform crystals.
A study analyzing whole-genome sequences from 1,050 Polynesian individuals reveals the history of voyaging is written in their genomes, offering new clues to health risks and medical discoveries. The research also identifies genetic variants associated with autosomal recessive diseases at high frequencies in French Polynesia.
Two Scripps-led studies demonstrate the effectiveness of underwater acoustic enrichment in spurring coral and fish recovery efforts. The studies, conducted in Hawaii's Kāne’ohe Bay, show that playing sounds from healthy reefs can increase the presence of coral larvae and fish larvae on artificial reef structures.
A study found that statin use is associated with a lower risk of developing open-angle glaucoma and needing stronger treatments like surgery. Statins were linked to reduced risks of glaucoma surgery and minimally invasive procedures, suggesting potential benefits for optic nerve health.
Research finds that people with depression using psilocybin still pursue mental health care at similar rates to nonusers, but report unmet needs for services. This suggests that psilocybin is being used as an adjunct to traditional therapy, rather than a replacement, according to a new study.
Researchers found that movement-evoked pain activates the brain's Default Mode Network (DMN), which is associated with self-reflection and identity. This suggests that treatments like mindfulness and psilocybin may be more effective than traditional symptom-based approaches in managing chronic low back pain.
Researchers will create coast-to-coast infrastructure to study biological systems in three dimensions. The observatory will integrate advanced imaging capabilities, artificial intelligence, and powerful data networks to enable new discoveries in neuroscience and life sciences.
UC San Diego Health has adopted new coil technology and FDA-approved liquid-based treatment for chronic subdural hematoma, expanding minimally invasive treatment options. These advances provide more options for customizing treatment based on a patient's anatomy and clinical needs.
The new center will bring together researchers from various disciplines to study the biological factors contributing to addiction across multiple substances. Researchers will examine biological systems, brain networks, and gene activity to understand individual differences in addiction risk.
A 12-month exercise intervention improved attention and memory in breast cancer survivors, while a companion study found exercise slowed epigenetic aging. These findings suggest exercise may help buffer against cognitive effects associated with accelerated epigenetic aging.
Liangfang Zhang's invention uses human cell membranes to cloak nanoparticles, making them deliver drugs and remove toxins more effectively. The approach has shown promise against bacterial toxins, including MRSA, and may potentially treat diseases without conventional drugs.
A study from the University of California San Diego School of Medicine found that 11.4% of older adults who used cannabis in the past year met the criteria for cannabis use disorder (CUD). This condition is characterized by a pattern of cannabis use that causes problems or interferes with daily life. The study highlights the importance...
Researchers at the University of California San Diego have developed a new approach to switch magnetic states using light, which could lead to faster and more efficient data storage. By shaping and shrinking light, they were able to overcome limitations of previous methods and achieve optical switching in thicker magnetic materials.
Researchers developed a method to test cosmic uncertainty in the universe's oldest light, which could provide evidence for physics beyond the Standard Model. The team compared maps from different detectors to establish the calibration pattern, finding consistency with existing analysis.
Scientists tracked brain activity of schooling glassfish to uncover how animals detect social partners' actions, allowing groups to escape danger. The study found that social behavior is crucial for coordinated escape, with groups responding more effectively to threats than individual fish.
Researchers at UC San Diego identified a naturally occurring peptide called catestatin (CST) that reduces toxic protein accumulation, neuroinflammation, and improves cognitive function in mouse models. CST may provide a new peptide-based therapeutic strategy for Alzheimer's disease and related neurodegenerative disorders.
By creating virtual cells from 4D AI models and digital twins, researchers can predict how mitochondria respond to drug treatment, grouping cells that respond similarly together. This technology has the potential to speed up drug discovery and accelerate research for diseases such as cancer, diabetes, and Alzheimer's.
Researchers identified a distinct risk profile for young adults with early-onset fatty liver disease, associated with genetic factors and metabolic conditions like type 2 diabetes. The study highlights the need for more accurate liver screening and assessment for individuals at greatest risk.
Researchers identified a natural antibody, anti-NMDAR1, that may protect the brain after traumatic brain injury, reducing the risk of depression and PTSD. The study found that Marines with higher levels of the antibody had lower depression and PTSD symptoms after a TBI.
Researchers at University of California San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded, eight-letter genetic alphabet. This breakthrough advances synthetic biology and could allow scientists to create new biological systems and diagnostic tools.
Researchers developed a method to distinguish authentic ancient clay artifacts from fakes by analyzing the magnetic properties of the clay. By measuring the temperature needed to erase magnetism acquired over time, the method can determine the age and authenticity of the artifact.
A new study from the University of California San Diego reveals that the brain tracks subtle variations in breathing to decode neural activity patterns. Researchers found a precise connection between breathing patterns and brain activity, offering new avenues for understanding disorders like SUDEP and SIDS.
Researchers at UC San Diego will develop optimized red blood cells to temporarily boost human performance and health through enhanced oxygen delivery. The project has the potential to improve athletic performance and treat conditions involving oxygen delivery to tissues.
Researchers at the University of California San Diego used computational models and virtual reality to study the social interaction rules of schooling fish. They found that individual fish 'copy' the movement direction of a randomly-chosen nearby neighbor, leading to highly dynamic behavior in groups.
A UC San Diego study links certain agricultural and natural landscapes to Valley fever rates, suggesting land management decisions can impact public health. Research analyzed 65,657 confirmed cases and found higher disease rates in areas with dry, sparsely vegetated landscapes and certain types of farmland.
Scientists in the University of California San Diego laboratory used AI to decipher the 'initiator' DNA sequence, which is responsible for gene activation. The researchers found that about 60% of human genes contain the initiator, enabling the prediction of DNA mutations that can lead to various disorders.
Scientists discovered a previously missed DNA mutation pattern in colorectal cancer, found in 3 independent datasets of 2616 tumors, suggesting a new mechanism of DNA damage accumulation. The pattern appears relatively late in tumor development and is associated with small insertions and deletions in DNA.
Researchers at the University of California, San Diego, have developed an inexpensive solution to the path-obstruction problem in millimeter wave wireless communications. Their passive reflective tiles, called FlowForm, can nearly double average data rates indoors and double wireless coverage area in challenging environments, matching ...
The five-year Brain-FRAMe program aims to improve clinical care and brain health for people with HIV and active methamphetamine use disorder through innovative, multidisciplinary treatment approaches. The program investigates the combined efficacy of long-acting injectable ART and medication for addiction treatment.
A team of computer scientists at the University of California San Diego developed a device that can take over communications between two key flight computers on a Boeing 737 by plugging into an unused maintenance port. This attack can be carried out in under 60 seconds, posing a significant risk to aviation security.
The West Health Accelerator will expand UC San Diego Health's ability to ensure every patient gets the right care at the right time in the right setting. The six-year initiative aims to raise the standard for health systems across the country, leveraging advanced technologies and data analytics.
High-frequency brain waves called ripples facilitate long-range neural communication during working memory tasks, suggesting a mechanism for integrating information. The study's findings may also help differentiate healthy cognitive signals from abnormal activity associated with neurological diseases like Alzheimer's or ADHD.
The University of California San Diego and San Diego County have developed a tool to track the New World screwworm, a parasitic fly whose larvae feed on living tissue. The dashboard combines reports of confirmed detections, environmental suitability, and media coverage to estimate risk nationwide.
Researchers at UC San Diego identified a key cellular pathway that drives brain degeneration in both Sanfilippo syndrome type A and Alzheimer's disease. The study reveals how the brain's immune cells respond to waste buildup, providing a novel target for drug development.
The Stein Institute at UC San Diego will serve as the Central Laboratory and Biorepository for the XPRIZE Healthspan Competition. The 10 finalist teams will conduct coordinated clinical trials worldwide to test their treatment approaches, aiming for a decade-long extension of human healthspan.
Engineers have created a bacterium that can consume all three major sugars present in corn stalks, opening up possibilities for more efficient biomanufacturing processes. The new strain of Pseudomonas putida was developed using an automated culturing platform and can potentially be used to produce valuable molecules like indigoidine.
A new study suggests that doctors' reassuring language can have the opposite effect on patients, making them less likely to seek treatment. The researchers found that normalizing symptoms can be misinterpreted as acceptable or not worth treating.
A new study reveals that Mindfulness-Oriented Recovery Enhancement (MORE) is highly effective in reducing opioid misuse and costs. The therapy, which combines mindfulness skills to regulate craving and pain, has been shown to provide $12 in cost savings for every dollar spent, with potential economic benefits of over $324,000 per patient.