Researchers at UCLA and California NanoSystems Institute create a material that exhibits quantum properties at room temperature, thanks to the addition of an amino acid called arginine. The discovery opens up new possibilities for advanced materials and technologies, including energy-efficient computer memory.
A global team of researchers has launched the largest-ever study of brain function across eight mental illnesses, analyzing over 94,000 brain scans from 27 countries using a shared method. The study aims to identify brain signatures specific to each illness, drive discovery, and inform treatment response.
Camille Bilodeau, a UVA assistant professor, has been recognized for her contributions to chemical engineering. Her lab develops computational tools to predict molecular behavior, addressing challenges in targeted drug delivery, tissue engineering, and water purification.
A study published in the Journal of General Internal Medicine found that New York City's tenant right-to-counsel program was associated with lower rates of all-cause emergency department visits among low-income residents at high risk of eviction. However, the program was linked to an increase in ED visits related to mental health and s...
A team led by Professor Mo Khalil is creating small protein-based tools called nanobodies to alter protein activity and study disease mechanisms. These nanobodies will enable large-scale experiments to understand how protein changes lead to different disease states.
Researchers propose using aging rate indicators to detect interventions that slow aging pace. The study aims to accelerate anti-aging breakthroughs, but regulatory barriers and equitable access are discussed.
A review highlights how altered fatty acid metabolism fuels glioma growth, reshapes immune responses, and influences treatment sensitivity. Fatty acid metabolism-based treatments, such as an FASN inhibitor, have shown promise in improving progression-free survival rates.
Researchers developed a biomimetic mineralization-immobilized whole-cell biocatalyst for efficient nicotinic acid production. The biocatalyst achieved 14 reuse cycles, producing 603.56 g/L nicotinic acid with a total molar conversion of 90.2%, significantly outperforming free cells.
Researchers at Eötvös Loránd University found statistical evidence that some supermassive black holes are ejected from their galaxy centers after forming. Quasars containing faster-moving black holes are, on average, redder, indicating more dust obscures them.
Gustave Roussy physicians and researchers showcase promising studies on immunotherapy and digital health at the ESMO 2026 Congress, aiming to improve treatment outcomes for cancer patients. The institution's UNLOCK programme and other initiatives are highlighted as key contributors to these advancements.
Research reveals that family heirlooms are not simply discarded, but rather, heirs consider how to pass them down to new owners and preserve their legacy. Descendants often opt to keep heritage goods together as a set to maintain the family history and integrity of the item.
A new study reveals that LSD speeds up brain rhythms, increasing frequency and making brain activity more fractal, unlike other psychedelics. The accelerated brain activity is unique to LSD and is associated with altered perception and introspection.
Researchers at Washington University in St. Louis have developed a hybrid chemical sensing system combining an insect's natural sensing abilities with nanomaterials. The system, which adds a ultralight nanomaterial coating to locust antennae, improves odor-detection performance across a wide range of chemicals, including TNT.
Mississippi State University has been awarded $90,000 by the US Department of State to lead a trilateral initiative on innovative energy research collaboration with Bahrain and the UK. The SPARK project will strengthen research partnerships, expand technical exchange, and advance practical solutions in emerging energy technologies.
To limit global warming to 1.5°C, global greenhouse gas emissions must be reduced by 18% by 2030, 45% by 2035, and 69% by 2040. The report finds that even achieving additional net-zero targets will only limit warming to 2.1°C.
The Office of Naval Research has selected 180 CNR Fellows from 70 institutions, providing technical insight and new research opportunities. The program aims to strengthen connections between the DON and academic community, supporting Sailor and Marine technological edge.
A new study by NYU Tandon School of Engineering found that 86% of AI-generated advice fell short on accuracy, completeness, or safety, and 60% omitted critical safety warnings. Researchers tested four AI systems, including IPV-specific chatbots, and found that most responses were rated unsafe or incomplete.
Researchers at USC Rossier and the University of San Francisco document how state officials use extra-legal tactics to silence local education leaders, threatening their jobs and reputations. The study highlights the personal and professional toll of these pressures, including threats, therapy, and social media avoidance.
A new study challenges the long-held hypothesis that early land animals evolved flexible necks for turning their heads. Using fossil anatomy and biomechanical studies of a modern fish, researchers found that early tetrapod necks were stiff and did not allow much mobility.
Engineers at the University of Cincinnati developed a system to detect damaged drones using sound recordings. The system can alert operators before takeoff, preventing crashes and ensuring public safety. The technology aims to enable fully autonomous drones that can detect damage and return to base before catastrophic failure.
The study found that coastal bears have reduced genetic diversity and elevated inbreeding, while mountain bears have two distinct, genetically healthy groups. The researchers hope that the genomic data will aid wildlife managers in sustaining a healthy bear population and improving population resilience.
A University at Buffalo breakthrough enables the creation of thousands of detailed protein maps, revealing how disease and treatment reshape tissue biology. This technology has the potential to transform drug therapies by uncovering new therapeutic targets and guiding the development of safer, more effective medicines.
Researchers at UTHealth Houston will study psilocybin-assisted therapy for individuals with co-occurring cocaine use disorder and major depressive disorder. The 12-week study aims to evaluate psilocybin's potential in reducing depressive symptoms and increasing abstinence from cocaine.
Ochsner Children's NICU is part of an international research network dedicated to improving outcomes for infants born at or before 23 weeks' gestation. The collaboration aims to advance research, identify best practices, and support families of extremely premature infants.
Rice researchers have developed an ultraporous material capable of pulling several valuable and rare earth elements from complex waste streams. The material, modified with a molecule called phosphonomethyliminodiacetic acid, allows for the recovery of critical minerals from industrial wastewater, a potential step toward recycling.
Researchers at Rutgers University developed a needle-free mRNA vaccine that protected mice against COVID-19 and flu, offering a potential new delivery method. The vaccine combined a high-pressure liquid jet with adjuvants to strengthen the immune response, and showed improved efficacy and safety compared to traditional mRNA vaccines.
Researchers have discovered that polyion clustering plays a crucial role in liquid-liquid phase separation, challenging decades-old assumptions in the field. This process is essential for the formation of biomolecular condensates, which perform vital tasks necessary for life.
Digital platforms are changing the way young people participate in civic activities, with online spaces providing new opportunities for expression and engagement. Young people from diverse backgrounds are using social media and online tools to raise awareness, mobilize others, and challenge dominant narratives.
Researchers from UC San Diego will join a national effort to accelerate the search for treatments for Alzheimer’s disease. The platform trial will test multiple combinations of natural products, repurposed FDA-approved drugs, and other potential therapies simultaneously using blood-based biomarkers.
Researchers outlined a roadmap for developing state-of-the-art precision diagnostic tests to detect early signs of injury and rejection in xenotransplantation. The framework includes enhanced tissue diagnostics, continuous monitoring, and advanced research platforms to improve long-term outcomes for patients.
Ken Stedman, a renowned virus researcher, has been named an International Collen-Francqui Professor, recognizing his expertise in virus survival and evolution. He will collaborate with four Belgian universities, bringing new opportunities for students and research collaborations.
A study published in Nature reveals that deforestation and wildfires have reversed the Amazon's CO2 balance, rendering it unable to sequester greenhouse gases. The region's carbon balance has shifted, with emissions exceeding absorption by nearly 40% annually.
Researchers found that people who received early rhythm control had an 8% risk of a second stroke, compared to a 14% risk for those who did not receive treatment. Early rhythm control was also associated with a 44% lower risk of stroke and a 28% lower risk of death from all causes.
Jackie Sherrill, a two-time national champion coach, will receive the Paul ’Bear’ Bryant Lifetime Achievement Award in 2027, recognizing his outstanding career accomplishments and dedication to developing young people. The award supports the American Heart Association’ lifesaving mission, honoring coach Bryant’s legacy and celebrating ...
Researchers discovered that iron deficiency during pregnancy can cause lasting changes in brain development, including altered gene expression and myelin formation. These changes can affect cognitive function and may not be fully rescued by iron supplements.
The University of California, San Francisco has been awarded $5M in federal funding to launch a national center to improve dementia detection and management. The center will translate evidence-based approaches into practical tools, training, and technical assistance to bridge the gap between research and practice.
Researchers found that anticoagulant use was associated with a lower risk of ischemic stroke and death in people with AFib who had brain bleeds, with 83% lower risk of ischemic stroke and 80% lower risk of death. Newer anticoagulants were not associated with an increased risk of brain bleeds, while warfarin was.
The Estonian parental benefit has increased the likelihood of having a second or third child, as well as shortened the interval between births. This is particularly true for mothers with higher education qualifications, who receive benefits that compensate for their previous income.
A recent study from the Estonian Biobank surveyed nearly 46,000 participants to explore the causes of side effects from medicines and vaccines. The results show that side effects are common, affecting 29% of respondents, with women more likely to experience them. The study also found that side effects can influence treatment decisions,...
Researchers have discovered magnetic reconnection eruptions and Coronal Mass Ejections near supermassive black holes, similar to solar storms. The 'Neupert effect' was observed in the galaxy NGC 3783, indicating the same physical processes underlying solar storms occur in black hole environments.
Researchers recorded strong and unusual currents in the 2.4-kilometer-long canal, which can amplify water movement under certain atmospheric conditions. The study found that oscillations with periods of several dozen minutes can occur, posing a danger to vessels and coastal management.
Oreejoy's AI-powered wearable device uses pressure sensing, signal processing, and artificial intelligence to assess mobility and provide personalized sensory cues for people with neurological disorders. The startup aims to make effective diagnostics and rehabilitation more accessible, improving quality of life for patients undergoing ...
Insilico Medicine is presenting first-in-human data for AI-designed cancer drug ISM6331, a pan-TEAD inhibitor targeting the Hippo/TEAD pathway in mesothelioma and other advanced solid tumors. The study's results will be discussed at the ESMO Congress 2026.
The New Jersey Supercomputer Initiative (NJSCI) aims to advance research, innovation, education, and workforce development across New Jersey. The initiative will establish a shared supercomputer to support researchers, students, and businesses, enabling them to tackle complex challenges like cancer research and flood risk mapping.
Researchers have identified new predictors of relapse in children with acute lymphoblastic leukemia treated with immunotherapy drug blinatumomab, allowing for more precise treatment tailoring. The study also found genetic subtypes associated with poorer response to treatment and higher risk of relapse.
Drs. Bradley Schlaggar and Amy Bastian, both renowned experts in developmental neuroscience, have been elected to the National Academy of Medicine. Their groundbreaking work has been recognized for its impact on clinical care and public policy. As leaders in their fields, they will advance science and inform policy to improve health ou...
A new study links 12 blood proteins to prostate cancer diagnosed over 15 years after blood sampling, including immune cells and cancer driver genes. The research may help identify men at greater risk of aggressive prostate cancer and inform future studies.
A new study found that nearly one in five young adults in the US experience daily anxiety, with higher rates among women and LGB individuals. The study also revealed disparities in anxiety diagnoses and medication use across different racial and ethnic groups, highlighting the need for targeted support and resources.
A free online program, Mindful Mood Balance for Moms, has been shown to reduce depression relapse among new moms and moms-to-be. The program, which includes audio-guided practices, videos, and advice from peers and professionals, has been found to lower the risk of depression relapse by 26% among participants. The study, published in t...
A case report describes a patient who developed toxic epidermal necrolysis after combination therapy with pembrolizumab and enfortumab vedotin for metastatic urothelial carcinoma. The patient's high-grade urothelial carcinoma and recent radiotherapy may have contributed to the severe skin reaction.
A new AI platform, MAESTRO, has been developed to identify promising drug combinations for overcoming treatment resistance in prostate cancer. The platform uses large language models to analyze scientific knowledge and ranks the most promising candidates, providing a clear biological rationale for experimental testing.
A cold-spray technique has been developed to deposit sensors directly onto human skin and other flexible surfaces, providing strong adhesion and mechanical robustness. This innovation could lead to low-cost, expandable, and high-performing wearable sensors that enable continuous health monitoring and customized healthcare.
Researchers at McGill University found that urbanization is weakening the latitudinal diversity gradient, with tropical cities containing 42% fewer species than nearby natural areas. Preserving green space is a hopeful measure to allow birds and other species to coexist with humans.
Researchers found that mice genetically engineered to have dementia symptoms who received BCG vaccine showed reduced neurofibrillary tangles, sustained immune cell activation, and memory loss compared to untreated mice. BCG vaccination was also linked to reduced inflammation and improved cognitive function in the mice.
Adults create more original and effective ideas, while preschoolers are more confident and enjoy creative activities more frequently. The study suggests that adults' low self-confidence and anxiety inhibit their creativity, whereas preschoolers' enthusiasm and motivation drive their creative pursuits.
A new study published in PLOS One found that forensic specialists can accurately identify individuals with just one or two facial features, with ears being the most useful feature. The experts adapted their strategy depending on the face in front of them, rather than applying one fixed rule.
A study published in PLOS One suggests that attachment anxiety and vulnerable narcissism are associated with problematic social media use. Adults with anxious or fearful attachment styles and high levels of vulnerable narcissism tend to experience higher levels of compulsive social media use.
Researchers identified two common drugs, aspirin and lansoprazole, that may prevent early labor when given together during pregnancy. The study used a digital twin system to simulate the immune system of individual pregnant women and found that the combination had a large effect on delaying labor.
A large US-based study found loneliness to be the strongest factor associated with depression among cancer survivors. The study analyzed data from 70,620 adult cancer survivors and found that those who reported feeling lonely had nearly three times the odds of reporting a lifetime diagnosis of depressive disorder.
Rüppell's vultures exhibit a complex, graded vocal repertoire likely driven by their highly social nature, which may impact conservation efforts. The species' critically endangered status raises concerns about the long-term survival of this unique avian behavior.
Alcohol use during pregnancy has decreased in Finland over the past 35 years, but remains a significant concern. Unaware drinkers, who consume alcohol before realizing they are pregnant, pose a particular risk to fetal health.
Researchers identified a substance that reduces blood vessel lesions in the brain, a disease causing fragile blood vessel structures that can lead to hemorrhages and stroke. The substance, dabrafenib, is already used to treat brain tumors in children and could replace surgery as a treatment option for CCM.
A protein complex called the constitutive centromere-associated network (CCAN) assembles inside the cell, forming a spherical shell-like structure within the nucleus. This structure is essential for faithful segregation of chromosomes and is compromised when CENP-C is removed or prevented from binding to DNA.
Global health experts warn that public health institutions must verify the accuracy of AI-generated content to ensure public health information is trustworthy. The authors argue that knowledge is a public good and that sifting truth from AI-generated content is now a core responsibility for public health institutions.
Female Anopheles mosquitoes employ a 5-step process to bite humans, combining chemical sensing and biomechanical coordination. They bite faster and hunt for blood vessels more quickly than yellow fever-carrying Aedes aegypti mosquitoes, resulting in potentially painful bites.
A new digital twin model suggests that two out of nine FDA-approved drugs have the potential to slow preterm labor. The model, called Simulated Immunome Modeling of Clinical Outcomes (SIMCO), evaluates the impact of eight drugs on immune cell activity in pregnant and non-pregnant individuals.
Research suggests that reduced brain beta wave activity may be a neural marker for schizophrenia, correlating with speech distortion and clinical severity. The study monitored brain activity in patients and controls, finding that beta-band dynamics may signal a potential for targeted interventions.
Researchers have developed a device called Scentronic, which can detect and transmit scents across distances using artificial intelligence and machine learning. The device has the potential to improve nutritional outcomes for patients with sensory challenges and enhance food quality for astronauts and warfighters.
Researchers have developed a new therapeutic approach for SCA3, a rare neurodegenerative disease, by targeting the production of a harmful protein. The approach uses custom-designed drugs to reduce the levels of the disease-causing protein, preserving the normal protein's function.
A new analysis of clinical trial data highlights the delicate balance between preventing graft-versus-host disease and infections in stem cell transplant recipients. The study found that two immune-suppression treatments, cyclophosphamide and tacrolimus, have different effects on T cell immunity and the risk of complications. This rese...
Researchers found that Rüppell's vultures produce 16 distinct call types, using sounds to convey emotions and information. The study's findings could help improve captive breeding programs and shed light on the evolution of communication.
Researchers have created a new antifungal drug, mandimycin M16, which selectively targets fungal ergosterol without disrupting human cholesterol. This breakthrough could lead to safer and more effective treatments for fungal infections, including multidrug-resistant strains.
A new imaging agent JAS239 enables pinpointed removal of lung cancer tumors with near-infrared fluorescent imaging. The agent selectively binds to lung cancer cells and successfully accumulates in excised human lung tumors.
According to a study published in JACC: Advances, cardiac events are responsible for nearly half of all on-duty firefighter deaths in the US. The findings suggest that annual health screenings may miss heart conditions that put firefighters at risk of sudden cardiac death, such as coronary artery disease and heart muscle enlargement.
Researchers found that collective bacterial migration helps them stay ahead of phages, while also enabling phages to infect a fraction of cells near the migrating front edge. This coexistence relies on chemotaxis, or bacteria moving in response to changing chemical levels in the environment.
A pilot study tested an electronic nose, NOS.E, alongside human-remains detection dogs to detect buried human remains and confirm dog signals. The technology tracks chemical changes in decomposition, potentially helping trainers identify whether dogs need more training.
A new study led by UCL researchers found that crocodiles and their relatives followed warm climates wherever they moved, in hot periods spreading as far as Antarctica, and in colder ones retreating to the tropics. This helped them survive the asteroid that killed the dinosaurs.
Researchers discovered that plant proteins like OsNTP4 can assemble RNA chains directly from free nucleotides, challenging traditional RNA synthesis mechanisms. These proteins can generate RNA products without a template or primer, and their activity has been found to be intrinsic to the protein itself.
A European study found associations between air pollution, temperature variability, and blood glucose levels in people without diabetes. Greater exposure to air pollution, particularly PM10 particles, and increases in temperature and temperature variability were linked to higher blood glucose levels.
A team of researchers from Penn State has developed a fluorescent molecular tag that tracks viral RNA and host interactions in real-time, allowing for the study of Zika and chikungunya viruses. The tool, called Mango-II, provides insight into the viral-host cell interaction, a key step to developing effective antiviral strategies.
Researchers reconstructed 16,000 years of summer temperature changes in the Western Balkans using lake sediments and tiny insects. The findings show that temperatures warmed by up to 2.9°C between 11,800 and 11,400 years ago, and cooled by 2.3°C during the Younger Dryas event.
Researchers at Johns Hopkins Medicine report a 96% survival rate among children with severe aplastic anemia treated with half-matched bone marrow transplants from family donors. The approach expands access to potentially curative treatment, with patients experiencing strong engraftment and durable survival rates.
A new review of 30 studies found that co-viewing with parents and choosing prosocial content can help young viewers make sense of what they see. Heavy screen use can also lead to sleep problems and push out other activities.
A new AI-powered tool allows for precise estimates of bee activity, complementing traditional methods in pollinator monitoring. The tool, developed by UMass Amherst ecologist Laura Figueroa, uses audio recordings to identify bee species, achieving high precision rates and correlation with visual observations.
Researchers found evidence of avian influenza infections in polar bears in eastern Greenland, highlighting the growing concern of disease transmission in Arctic ecosystems. The study suggests that climate change is increasing the bears' exposure to new pathogens, making them more vulnerable to infections.
Researchers from the University of Ottawa and collaborators developed brain-inspired computing systems, promising a fundamentally different way to process information. These emerging technologies will lead to physical devices that are dramatically more energy-efficient, faster, and adaptive, enabling greener technology and smarter wear...
A new trial shows that a shorter three-week radiation course is as safe and effective as the standard five-week treatment for women undergoing breast reconstruction. The RT CHARM trial found no increase in complications or effects on reconstruction efforts.
The research team developed a fully tunable on-chip meta-generator, enabling compact control of structured light fields with high mechanical stability and multi-dimensional tunability. The platform achieves breakthroughs in waveguide mode multiplexing and full-surface dynamic remapping across diverse Poincaré spheres.
Researchers have investigated the motion of liquid membrane structures, revealing a regime intermediate between liquid interfaces and elastic membranes. The study finds that liquid membranes exhibit entropy-dominated bending dynamics, differing from enthalpy-driven processes in lipid membranes.
The MEDA-PKD platform uses real-time data from clinical practice and research to provide insights for personalized care. The platform has demonstrated medically relevant insights, such as slowing down kidney function loss with tolvaptan treatment.
The SpongeBoost project aims to restore natural water retention in European landscapes through innovative approaches and community engagement. Nominations are open until October 31, 2026, for projects that demonstrate effective restoration, collaboration, and environmental education.
Climate change may have enabled Candida auris to become a deadly fungal pathogen worldwide, with a high mortality rate in cases of blood infection. Researchers propose early warning systems and preventive measures to tackle the spread of fungal diseases.
A recent study in Finland found that reindeer grazing reduces tree and understorey roots, particularly in the upper 0-5 cm of soil, and changes root structure, which may impact water and nutrient uptake. This could have significant effects on forest carbon and nutrient cycling.
Swiss barn owls have evolved to become more reddish-brown and heavily spotted over 30 years, driven by natural selection. Their plumage colour is linked to fertility and hunting strategies, with spotted owls appearing more resilient to stress and diet.
Mitochondrial oxidative stress is a key driver of autoimmune diseases, with each disease having unique barriers to treatment. The review proposes a single therapeutic target, targeting the interconnected regulatory network of five pathways, including NRF2, AMPK, SIRT1, and mitophagy.
Professor James Ebdon, an environmental microbiologist, has been named winner of the John Snow Public Health Innovation Prize for his work on water and sanitation. He has made significant contributions to understanding the role of water and sanitation in the spread and control of water-related diseases.
Professor Stephen Obaro has been recognized for his work in applying microbiological insights to inform policy and drive systemic change. His research focuses on reducing preventable childhood deaths from infectious diseases, with evidence generated from his studies helping to inform global vaccine development and disease surveillance ...
Tamim Asfour has made significant contributions to the development of humanoid robots that can perform complex tasks and learn from humans. His research has led to the creation of cognitive robots with episodic memory, enabling them to store, retrieve, and describe experiences in natural language.
A new materials library was created to improve sodium-ion battery performance, with iron and vanadium linked to higher energy storage and stability. The library could eventually allow AI to identify new battery compositions before they are made, accelerating the development of better sodium-ion batteries.
Global measles vaccination rates for children under 5 have declined post COVID-19, with estimated cases rising 40% from 11.1 million in 2019 to 15.6 million in 2023. The resurgence coincides with COVID-19-related disruptions to immunization programs and health systems.
Researchers found quercetin slowed lung cancer cell division and reduced oxidative stress, while increasing Interferon-alpha-2 and gut microbiome, suggesting a potential quercetin-rich diet for lung cancer treatment and prevention
A study by Anglia Ruskin University identifies Jeronimus Cornelisz, a 17th century trader, as the world's first corporate psychopath, exhibiting modern toxic leadership traits 400 years ago. The research found that Cornelisz displayed all 10 core characteristics associated with corporate psychopaths, including manipulating followers an...
Researchers have developed a new optogenetic tool that selectively inhibits neurons and heart muscle cells by activating a G-protein-coupled signaling pathway with blue light. The tool, Opn4L/GIRK1, has been shown to decrease the spontaneous beating rate of human heart muscle cells and inhibit the activity of cerebellar neurons.
A study of 1,300 students aged 10-18 found that motivation and responsibility are crucial in preventing bullying in physical education. Students who are more motivated to participate in physical education are more likely to show personal responsibility and actively intervene when faced with unfair situations.
A new review examines how gut microbiota and metabolites reshape liver immunity and propose strategies to overcome immunotherapy resistance. The review discusses four major directions of gut microbiota intervention, including probiotics, fecal microbiota transplantation, engineered bacteria, and metabolite-based interventions.
Researchers at HIPS used AI to design new building blocks for active ingredient production, resulting in functional proteins with improved pharmaceutical properties. The AI-designed building blocks increased yield up to three times compared to natural variants, making it easier to obtain new compounds for research and development.
Researchers at Institute of Science Tokyo used integrated forensic methods to analyze a single tooth, revealing clues about birth year, age at death, dietary patterns, drug exposure, biological sex, and DNA profile. Stable carbon isotope analysis and amino acid racemization provided accurate estimates of birth year and age at death.
The book examines the security challenges and emerging practices associated with Cyber-Physical Systems (CPS), including blockchain, cryptography, and steganography. It discusses secure authentication, data transmission, and strategies for improving system reliability and resilience across various industries.
The review highlights the importance of protein homeostasis in donor cells, particularly in the context of senescence and extracellular vesicle (EV) cargo. Researchers propose targeted clearance of misfolded proteins, such as oxidized SOD1, as a pre-transplant strategy to improve therapies for various diseases.
Researchers propose a new approach to targeted chemotherapy, using pH-sensitive polymers to release drugs at acidic tumor sites. The system relies on glucose priming to transiently widen the pH gradient, triggering release from ultra-pH-sensitive carriers. This approach aims to overcome the limitations of current chemotherapy, which of...
This edited volume examines the evolution of staycations, rural hospitality, eco-tourism, and wellness tourism, highlighting their economic, cultural, and environmental significance. Researchers and practitioners explore contemporary themes, including workcation culture and social media marketing.
AI is increasingly being used in stroke rehabilitation to predict recovery trajectories and monitor motor function, providing adaptive and continuous care. The review highlights the need for standardized outcome measures and data pipelines to determine the clinical impact of AI-based monitoring.
Researchers have developed a triple-layered artificial nerve conduit embedded with living cells that steers nerve regrowth across deep gaps, achieving functional recovery in rats that rivals a natural graft. The bioprinted nerve 'railway tracks' guide regenerating tissue, promoting axon-guidance genes and restoring electrical impulses.
A meter-scale flapping-wing robot demonstrates the benefits of low-angle takeoff, increasing flight distance by 49% and horizontal distance by 123%. The robot's ability to control pitch attitude through the flapping-pitch effect enables early acceleration and speed advantage.
Researchers identified cell-type-specific circadian gene programs and phase-specific pathway activities in liver and skeletal muscle. The study provides evidence for a cell-type-resolved circadian landscape and candidate transcription factors, suggesting potential circadian therapeutic windows.
A new study warns of the increasing impact of climate change, urban living, and digital misinformation on sleep health across Europe. The researchers call for coordinated action to protect sleep health, improve sleep health literacy, and tackle structural inequalities.
The strain accelerates wheat straw decomposition, reduces fungal proliferation, and decreases aflatoxin content, promoting peanut seedling growth and supporting sustainable agriculture. SQ1 functions as a dual-purpose biocatalyst, breaking down cellulose and inhibiting fungal growth.
A new study has reconstructed the genetic history of the Iberian Peninsula between the 1st and 8th centuries CE, revealing that Roman Hispania's genetic legacy survived the arrivals of the Suebi, Alans and Visigoths. The study found that Roman rule created an extraordinarily diverse society due to population movements across the Medite...
Jennifer Lewis, a Harvard professor, has been elected to the National Academy of Medicine for her pioneering work in 3D bioprinting and vascularized organoids. Her research focuses on developing functional materials for applications in printed electronics, artificial muscles, and human tissue engineering.
Researchers found women can expect to spend more years over their lifetimes caring for aging family members or friends, with a 3-year gap from men. This disparity extends to caring for parents, grandparents, and extended family and friends, highlighting the need for increased support and resources for caregivers.
A McGill University study found that Montrealers reduced their outdoor activities by only 5.8% when wildfire smoke warnings were issued, switching to more enclosed modes like bikeshare and public transit. The researchers suggest pairing advisories with practical incentives to encourage compliance.
Maladaptive brain-state locking (MBSL) is a lifespan hypothesis suggesting that distinct disorders converge on impaired state-transition or recovery dynamics. Candidate features include abnormal persistence, impaired transition, and delayed recovery, with lifespan timing and regional context modifying phenotypic expression.
A massive, 1-mile-thick ice shelf in Baffin Bay helped lock in three of the largest ice sheets in northern Canada and Greenland, contributing to hundreds of feet of sea-level rise. The discovery provides new insights into the future of Antarctica's massive ice sheets and the potential for sea-level rise.
Researchers discovered a signalling system regulated by metabolites that extends lifespan and delays age-related decline in animals. Muscle tissue produces the metabolite dihydrobiopterin (BH2), which is transported to other tissues to maintain protein homeostasis and tissue health.
Physicists at Northwestern University trap and cool a single positron, creating a controlled quantum state that allows for precise measurement of its magnetic properties. This breakthrough could reveal a crack in the Standard Model, offering new insights into the universe's matter-antimatter imbalance.
Researchers at Baylor College of Medicine discovered distinct astrocyte subtypes, CD51+ and CD51-, which have specialized jobs in forming synapses, shaping memory circuits and aiding recovery after stroke. These findings challenge the long-held assumption that astrocytes are uniform support cells.
Researchers discovered a new role for Wee1 in healthy cells, which could explain toxic side effects in cancer patients. Wee1 helps switch off a protein degradation complex, delaying cell division. This finding may lead to more targeted therapies and identify patients most likely to benefit from treatment.
A mouse study of Angelman syndrome identifies a potential opportunity to restore healthy neurodevelopment by targeting the buildup of a normally harmless enzyme, asparagine synthetase. The findings suggest that the enzyme's accumulation triggers a stress response that impairs brain growth.
A recent study found that overdose-reversing drug naloxone use did not increase relative to the number of overdoses in the US since 2023. Instead, nonfatal drug overdoses fell by 20.9% and opioid-related overdoses dropped by 32.7%.
Researchers have discovered a new way in which the Andes virus captures its receptor on human cells, a finding that could lead to effective therapies. The study reveals details on the molecular specifics of the interaction, including a deep groove or pocket that limits antibody access.
Zeolites can catalyze new olefin carbonylation reactions, enabling the selective production of chemical building blocks. The team discovered a key design principle: the location and size of zeolite pores determine which olefin molecules can be selectively carbonylated.
A Lehigh-led team is developing an AI platform called UniBrain to simplify brain imaging analysis, reducing the time and expertise required. The platform aims to unify image preprocessing and downstream brain network analysis, integrating information from multiple imaging modalities.
A study from Northwestern University found that a personalized fitness program for liver transplant candidates can significantly improve frailty and reduce mortality risk by 50%. The program, called prehabilitation, was linked to a lower risk of dying while awaiting a transplant.
Researchers at FAU's Harbor Branch Oceanographic Institute will investigate environmental and biological mechanisms driving harmful algal blooms in subtropical estuaries. The project aims to refine predictive models to mitigate blooms in other estuaries, with potential economic benefits of $28.3 billion.
Researchers at Chalmers University of Technology developed a new optimisation method for near-optimal large-scale fleet control, accounting for uncertainties in real-world transport systems. The method combines machine learning techniques with advanced optimisation models to predict travel demand and charger availability, improving fle...
Canadian Science Publishing launches a new collection of French-language scientific articles, strengthening the creation, dissemination, and mobilization of scientific knowledge in French. The inaugural collection features 14 articles exploring topics of significant importance, including forestry, Indigenous knowledge, and biodiversity.
New research models energy demand extremes in the US, finding that technology diffusion may have a larger impact than climate change on peak demands in certain regions. The study considers four climate change scenarios and 18 technology diffusion pathways in 183 counties across the US, projecting changes in extreme peak demands.
The BabyMERIT trial will evaluate trametinib in infants with Noonan syndrome and related conditions who develop severe hypertrophic cardiomyopathy, a potentially life-threatening condition. The study aims to improve outcomes for these young patients by targeting a molecular pathway known to drive these disorders.
A new open-source software package called PFclassify enables researchers to classify and quantify unprocessed and processed meats into separate subtypes, providing more accurate nutrition data. This gives scientists a standardized workflow to examine meat subtype-specific dietary intake, supporting more transparent and higher quality d...
Researchers have found that supernovae may not have played a central role in reionizing the early universe, contrary to long-held theory. Instead, young stars may have helped radiation escape, with winds from supernovae creating a barrier to ionizing radiation.
The grant will support Dr. Flanagan-Steet's research into understanding how metabolism and glycosylation work together during normal development and disease onset. The study aims to identify common biological pathways that contribute to rare diseases, with the ultimate goal of developing new treatments.
A consortium of researchers and clinicians aims to develop living cardiac tissues and components for infants and young children with congenital heart disease. The THUMPIN' initiative, supported by a $29.6 million contract, will create living heart tissue that can grow and adapt throughout childhood.
A new review shows how climate change alters microclimates, which can differ substantially from regional climate averages. Vegetation and atmospheric changes, such as cloud cover, influence local climate conditions, affecting biodiversity responses to climate change.
A new study from Okinawa Institute of Science and Technology uses computational models to shed light on the evolutionary origins of potassium conduits, identifying spike timing as a probable evolutionary pressure. The research suggests that higher unitary conductance channels, found in mammals and birds, were essential for achieving pr...
Researchers used Cell Painting to study 52 cancer drugs in 3D minispheres, revealing differences in how they affect cells. The study found that two drugs, 5-fluorouracil and olaparib, behaved differently when looking at individual cells, with 5-fluorouracil causing less DNA damage but stopping cells from dividing more effectively.
The ECOG-ACRIN Cancer Research Group will conduct a phase 2/3 clinical trial to evaluate ivonescimab combined with chemotherapy for first-line treatment of advanced biliary tract cancer. The trial aims to test the efficacy of ivonescimab beyond standard chemotherapy and immunotherapy.
Researchers found that higher postpartum depression scores were associated with greater mother–infant bonding difficulties, which can affect maternal well-being and child development. Repeated assessments identified varied symptom patterns, including mothers whose bonding difficulties increased during the first three months.
EPND+ builds on five years of public-private collaboration, supporting existing and future research collaborations in neurodegeneration and beyond. The new organization will operate the EPND Hub, providing a unified gateway to valuable research resources, data, and biosamples.
A recent study by Flinders University found that women with postpartum psychosis often contact healthcare services seven times before receiving a diagnosis. The research highlights the need for greater awareness of the condition and timely assessment to improve outcomes for mothers and their families.
Research found single mothers' children experienced decline in math, reading, and early motor development after EITC expansion, attributed to reduced time with parents. Increased employment among single mothers may outweigh income benefits for children's development, emphasizing need for affordable childcare.
Researchers have identified a gene that regulates tea plants' flavor and cold tolerance, providing insights into how to expand high-quality tea production. The study's findings suggest that targeting this gene could improve both flavor quality and stress resilience in tea plants.
Researchers found sustained increases in hospitalizations and deaths among Medicare beneficiaries aged ≥65 years in North Carolina after Hurricane Matthew. The study also showed a stronger association between hurricane exposure and hospitalizations and deaths, with Black individuals experiencing worse outcomes.
A study found that regular tea consumption was linked with an 11% lower risk of cardiovascular disease, with the lowest risk estimated at approximately 6–8 cups per day among weekly drinkers. Black tea showed more consistent inverse associations with vascular disease than green tea.
A study of 15 Australian women with postpartum psychosis found that they experienced delayed recognition, inadequate assessment, and dismissal of their concerns. The findings emphasize the need for professionals to listen to women's accounts and respond appropriately to improve outcomes.
New research suggests that heat-based recovery strategies may influence some biological processes involved in recovery following muscle-damaging exercise, but do not translate to significant improvements in muscle strength or soreness over a 72-hour period
Researchers used palaeoproteomics to analyze ancient proteins in sediments from a 60,000-year-old archeological site in South Africa, revealing the presence of collagen from the common eland. The findings provide new insights into the complex technical and symbolic behaviors of early Homo sapiens.
Researchers developed a heat-informed framework to assess available playing time and evaluate tournament schedules under hot conditions. The study found that adjusting playing hours had a stronger effect on the availability of low-risk hours than changing tournament dates.
Researchers found that IT vulnerabilities in automotive software have shifted to apps and cloud services, posing risks to driver data and car control. Experts advise car manufacturers to secure systems and encourage owners to update software and use strong passwords