The Leukemia Research Foundation has funded a two-year, $150,000 research project at the University of Cincinnati to develop a new treatment for TP53-mutated leukemia. The project aims to identify RhoA as a potential therapeutic vulnerability, which could make the leukemia more sensitive to existing treatments.
Researchers found a correlation between social media use and self-reported depression, with respondents who spent at least 150 minutes on social media per day experiencing increased depression. The study suggests that social media use can have negative health effects, particularly for adults.
Researchers at the University of Cincinnati have been approved for PCORI funding to implement healthy lifestyle interventions and metformin prescription to manage weight gain in SGA-treated youth. The project aims to increase the number of youth with overweight/obesity who are offered metformin and healthy lifestyle education.
Researchers have identified a potential target to prevent the spread of Chagas disease by using antimalarial compounds to interfere with the parasite's growth and development. This approach could lead to successful health interventions and save thousands of lives each year.
A UC study found that only 15% of eligible American adults discuss lung cancer screenings with their doctors, highlighting the need for increased awareness and education about the lifesaving procedure. The study suggests that stigma and fear around lung cancer, as well as lack of information about the low-dose CT scan, may be barriers ...
A 304-million-year-old warming event could inform scientists about rapidly changing Earth conditions. A small temperature spike led to a larger one from melting permafrost, with global sea surface temperatures rising by over 7 degrees Celsius.
A study published by University of Cincinnati associate professor Nelly Elsayed highlights the importance of human review in AI-driven physicians' documentation to ensure transparency, privacy, and reliability. The research also emphasizes the need for clinicians to be trained on software before adoption to curb errors.
The University of Cincinnati launches the Center for Alzheimer's and Neurodegenerative Diseases Research (CANDR) to improve dementia prevention and treatment outcomes. CANDR aligns with UC's mission to innovate and engage locally while addressing one of the region's most pressing public health challenges.
Researchers suggest using AI to strengthen ransomware defense by integrating synthetic data generation and behavioral forecasting. AI can detect new malicious attacks and classify unknown attack methods, helping to build trust among users.
New instruments promise precise measurement and manipulation of tiny nanomaterials used in manufacturing, aerospace and medicine. Researchers can now study the smallest heavy metals with water filters, developing more resilient structures.
A study by researchers at the University of Cincinnati found that insects respond to cycles of humidity in a predictable manner, similar to temperature and daylight. This suggests that organisms may be able to anticipate optimal conditions for survival, such as hydration or energy expenditure, based on humidity cues.
Satellite remote sensing allows researchers to monitor water quality by tracking changes in light spectrum, identifying nutrients in the water. This technology holds promise for studying global river health and detecting toxic algal blooms that can shut down water treatment plants.
A recent study by University of Cincinnati researcher Kimberly Hyun found that voices similar to our own are more persuasive, lowering our guard. The closer the vocal quality, the more likely we are to comply with a speaker's words.
Researchers found that adults with developmental disabilities who used integrated psychiatric and primary care models had lower odds of presenting to emergency departments and requiring hospitalization. The study suggested that integrated care centers co-locating physical and mental health services may provide better support for this p...
Researchers identified two weather patterns associated with an increased risk of headaches in the Northeast US. The study found that approaching cold fronts and high-pressure systems, such as the Bermuda High, can trigger new-onset headaches in people with episodic migraines.
A University of Cincinnati research team will examine how microplastics and nanoplastics accumulate in the body and affect cardiovascular health, with a focus on potential toxicity and worsening outcomes after a heart attack. The five-year study aims to advance understanding of microplastic impact on heart diseases.
Researchers found that patients who continue to smoke ahead of lung cancer surgery have a higher risk of pulmonary complications. However, their short-term mortality rate is similar to those who were able to stop smoking before surgery. The study suggests physicians reconsider traditional models and consider individualized plans for pa...
Researchers developed a nanofiber drug delivery system that uses electrospun fiber membranes to deliver multiple drugs in concert, demonstrating improved efficacy against glioblastoma. The system enables localized long-term delivery of drugs directly at the tumor site after surgery.
Researchers at the University of Cincinnati's Center for Advanced Structural Biology have visualized the structure of iRhom1 bound to the ADAM17 enzyme, shedding light on its role in regulating cell surface protein targets. This breakthrough discovery may lead to new therapeutic strategies for treating chronic inflammatory diseases.
Researchers at the University of Cincinnati found that embedding addiction treatment into primary care training clinics can expand access to care and boost physician confidence. The study showed marked improvements in resident education outcomes, including increased confidence in diagnosing and treating substance use disorders.
Researchers studied the unique planet using James Webb Space Telescope data, finding an atmosphere similar to Jupiter's, mostly composed of hydrogen and helium. The exoplanet orbits its star at just six Earth days, moving four times faster than Mercury around our sun.
A University of Cincinnati study proves the feasibility and scalability of collecting blood from patients in cardiac arrest during treatment. The approach, which involves paramedics delivering samples to a biorepository, showed significant variation among patients and underscores the need for further research.
A new clinical trial at the University of Cincinnati is testing a peptide solution to treat prosthetic joint infections after total knee replacement. The trial aims to reduce the need for repeat surgeries and expand the treatment window beyond two weeks.
A study by University of Cincinnati nursing professor Joshua Lambert found that students prefer the responses of a custom AI chatbot, but only when blinded to its source. However, when students suspected the response came from the chatbot, they rated it lower in terms of helpfulness and satisfaction.
The University of Cincinnati has established a new Center for Public Health, led by Dr. Suzanne Judd, a renowned epidemiologist and expert in health disparities. The center aims to transform community health through innovative research, education, and strategic advocacy.
The University of Cincinnati has opened a zebrafish research facility to investigate the effects of environmental contaminants on human fertility. The lab will use zebrafish as a model organism to understand molecular mechanisms behind reproductive biology and infertility.
Researchers found a clear connection between oral health and kidney health, with immune dysregulation and systemic inflammation driving the relationship. The study highlights the need for physicians to integrate oral and renal health into clinical care systems.
Researchers are analyzing real-world patient data to study the safety and effectiveness of GLP-1 drugs in preventing Alzheimer's. The study aims to determine if these widely available diabetes medications can delay or prevent the onset of Alzheimer's, a complex public health crisis that affects millions worldwide.
Researchers at the University of Cincinnati found that female caribou gnaw on shed antlers to supplement their diets with calcium and phosphorus, essential for milk production. The study, published in Ecology and Evolution, reveals a previously overlooked benefit of shed antlers in the Arctic ecosystem.
The University of Cincinnati's new UC/UC Health Addiction Center aims to improve addiction prevention and treatment outcomes through innovative research, enhanced clinical services, and education excellence. The center will coordinate activities across five UC colleges and 12 departments to foster interdisciplinary solutions.
Matthew J. Robson, PhD, a University of Cincinnati associate professor, received the 2026 Neuropharmacology Early Career Award for his research on serotonin neurotransmission and its impact on traumatic brain injury. The award honors young independent investigators in neuropharmacology.
The University of Cincinnati is conducting a clinical trial testing two new nonpharmacological treatments for depression in young adults. The trials focus on amino acid N-acetylcysteine (NAC) and mindfulness-based cognitive therapy (MBCT), with the goal of providing more treatment options for patients at higher risk of side effects fro...
Dr. David Gius, a renowned physician-scientist and radiation oncologist, has been appointed as the new director of the University of Cincinnati Cancer Center. He brings a robust research portfolio, including active clinical trials and NIH grants, to enhance regional access to superlative care.
A new study uses AI to predict substance use disorder-defining behaviors with high accuracy, providing a tool for clinicians to assess patients and offer timely treatment. The system utilizes concepts familiar in economics to evaluate human judgments and identify the type of substance used and severity of addiction.
Researchers found a synthetic protein, recombinant factor VIIa, can reduce bleeding in patients with a 'spot sign' on CT brain imaging who are treated within 90 minutes of stroke onset. These patients also experienced better outcomes and reduced ICH growth.
A new study from the University of Cincinnati College of Medicine emphasizes the need for updated treatment guidelines on reproductive health among patients with chronic kidney disease (CKD). The survey of 104 nephrologists found that sexual and menstrual health were rarely discussed, highlighting barriers to counseling.
Researchers at the University of Cincinnati Cancer Center are developing a new treatment for glioblastoma, a highly aggressive brain cancer. The team is using 'glioblastoma-on-a-chip' technology and wafer delivery to stimulate the immune system and improve patient outcomes.
A new study by University of Cincinnati economics professor David Brasington found that local business benefits from city services, particularly tax renewals, in Ohio. The research compared communities with renewed taxes and those with cut taxes, revealing a significant difference in commercial property redevelopment.
Researchers examined post-stroke symptoms and found patients with walking difficulties are more likely to be disabled, while those with numbness are less likely. The study also identified 'silent' swallowing problems after stroke, where survivors may not report any symptoms but still have real difficulty protecting their airway.
The University of Cincinnati Cancer Center is testing approaches to neutralize an enzyme complex that enables cell division in KRAS-mutated lung cancers. The grant aims to identify the best strategy to suppress this enzyme and prevent long-term tumor growth.
The University of Cincinnati College of Medicine has been awarded a $1.1 million AMA Transforming Lifelong Learning Through Precision Education grant to develop an AI-powered system for personalized learning and feedback. The project aims to improve the quality of medical education by providing real-time feedback on clinical reasoning ...
A new study by University of Cincinnati researchers found that men's sense of fulfillment at work is linked to their partners' views on money. Couples who align on the values of money tend to have higher job satisfaction, while those with differing perspectives experience lower job fulfillment.
A new research review identifies key barriers faced by military-affiliated workers in the civilian workforce. Employers can improve employee performance by offering targeted support to help bridge the gap between military and civilian life.
Medical students used ChatGPT to analyze survey responses and identify common themes, finding method three yielded the highest accuracy. The study showcases the potential for AI to assist with qualitative research in medical education.
Researchers at the University of Cincinnati have solved a long-standing problem in particle physics, using fusion reactors to produce subatomic particles called axions. This breakthrough has implications for understanding dark matter, which is thought to make up most of the universe's mass.
Researchers at the University of Cincinnati present a new BTK degrader called Bexobrutideg, showing an 83% overall response rate in relapsed CLL patients. The treatment also shows efficacy in patients with CNS involvement and those with BTK mutations that none of currently approved BTK inhibitors are effective against.
Researchers have identified critical cellular targets to improve pancreatic tumor sensitivity to KRAS inhibitors. The team found that certain patient populations may preferentially respond to anti-KRAS and anti-EGFR combination therapies.
A new clinical trial enrolls patients at the University of Cincinnati to study the effects of extended tranexamic acid dosing on recovery outcomes for young athletes after ACL reconstruction. The trial aims to test whether this approach can reduce pain, swelling and promote earlier movement in patients.
Researchers observed monk parakeets gradually approaching strangers before forming relationships, with caution escalating into friendly behaviors. This study reveals the benefits of 'testing the waters' in social interactions, potentially applicable to human friendships and social bonding.
The University of Cincinnati has received a $985,000 grant to test Healthy Eating for My Infant (HEMI), a community-based intervention promoting healthy eating and feeding practices for children 0-12 months. HEMI aims to address specific risk factors and barriers faced by low-income families. The NIH-funded study will enroll 60 infants...