A team of researchers used machine learning to analyze changes in astrocyte cells' structure, shedding light on heroin addiction and relapse. The study, published in Science Advances, found that specific subpopulations of astroglia exhibit more pronounced morphological changes during drug use.
A University of Cincinnati study found large, opposite moves in housing prices between low-income and high-income communities when analyzing police budgeting. Low-income areas saw a 13% increase in housing prices after increasing police spending, while high-income areas saw a 14% decrease.
Researchers from the University of Cincinnati Cancer Center presented abstracts highlighting contrasting effects of a protein on head and neck, breast, and lung cancers. The study found increased levels of IL-9 in patients with head and neck cancer correlated with decreased survival, while elevated IL-9 was associated with smaller tumo...
A University of Cincinnati study explores the link between health literacy and fear surrounding cataract surgery, revealing no correlation between the two. The research emphasizes the importance of open communication and building relationships to overcome fear.
David Niven, a University of Cincinnati political scientist, has been awarded a $200,000 Andrew Carnegie Corporation fellowship to investigate the American polling system. His research aims to analyze how voters' experiences at the polls impact their views on voting.
University of Cincinnati researchers, in collaboration with end users, develop a user-centered, easy-to-use assistive device to help restore hand grasping motions. The team aims to combine an exoskeleton device with functional electrical stimulation (FES) technology to create a hybrid system.
Researchers found that fruit flies that successfully evade mite attacks at night lose valuable sleep, sacrificing energy and nutrients. The study's lead author noted that sleep deprivation can have detrimental effects on animal health and behavior.
The US opioid epidemic has shifted its epicenter from the Northwest to the East, with a significant increase in fentanyl-related deaths. The study found that populations affected by substance use disorder have changed over time, with Black communities now disproportionately affected.
Researchers studying ancient rhino teeth found at Nebraska's Ashfall Fossil Beds State Historical Park discovered that prehistoric rhinos lived in large herds. The animals' limited mobility suggests they didn't respond to the volcanic eruption or migrate seasonally, instead likely dying from prolonged exposure to ash and lack of food.
A Phase 3 trial found that ChemoID improves objective response rates, median progression-free survival, and duration of response in patients with recurrent platinum-resistant ovarian cancer. The test identifies effective treatments by challenging cancer stem cells against specific anticancer drugs.
A University of Cincinnati study found that machine learning models can aid clinicians in treating patients with spreading depolarizations (SDs), a condition that can cause significant brain damage. The algorithm was able to identify SD events with high sensitivity and specificity, detecting many events not identified by human scoring.
A new study by J.Z. Bennett finds that long sentences for juveniles sever ties made while incarcerated and hinder progress upon release. The research highlights the importance of prison friendships, social connections, and emotional support in facilitating successful reintegration.
Researchers are conducting a clinical trial to find the optimal combination of pain management tools for patients undergoing mastectomy procedures. The study will enroll approximately 100 patients and examine various combinations of pectoralis nerve blocks, non-opioid analgesics, and administration methods.
A recent study in Nature Communications reveals that white blood cells employ a novel mechanism to dislodge bacteria from human tissues using brute force and integrin-based adhesion rings. The research, led by Xuefeng Wang, has significant implications for understanding the role of macrophages in cleaning up environmental pollutants.
Researchers from UC and Oak Ridge National Laboratory have made a breakthrough in understanding how alcohol damages microbes that produce it. The study reveals the primary location of toxicity is in the cell membrane, which can be stabilized to increase efficiency in biofuel production.
The University of Cincinnati is testing a collaborative care model to provide mental health resources to youth in rural communities. The program uses a tiered approach, starting with school counselors and progressing to licensed therapists and expert telehealth services, aiming to increase access and reduce barriers.
A new University of Cincinnati trial is comparing two types of omega-3 supplements, LPC-DHA and TAG-DHA, to slow or prevent dementia progression in elderly adults. Researchers aim to investigate whether LPC-DHA supplementation increases CSF DHA levels and improves cognitive function.
Researchers found that combining ultraviolet light with chlorine significantly enhances toxin degradation in water without generating harmful byproducts. The study suggests using UV/chlorine as a final barrier against toxins from algal blooms, minimizing unintended toxic consequences.
Researchers are testing noninvasive electrical stimulation of the spinal cord to treat major depressive disorder. The trial, funded by the National Institute of Mental Health, aims to confirm whether this method reduces signaling in specific pathways related to depression.
A University of Cincinnati researcher has been awarded a $2.1 million grant to investigate postoperative pain at the molecular and cellular levels. The goal is to develop new, safer non-addictive treatments for chronic pain conditions, including lower back pain and pain associated with diabetes or chemotherapy treatments.
Researchers examine how stroke patients develop post-stroke sensory reweighting (PSR) to improve walking and balance. PSR is a critical factor in determining patient outcomes, with those who develop it experiencing better balance and reduced risk of falls.
Researchers at the University of Cincinnati presented studies on intracerebral hemorrhage treatment eligibility, finding only 3% of patients are eligible for a minimally invasive procedure. Additionally, a study found racial disparities in stroke recovery, with Black individuals experiencing worse functional outcomes after ischemic str...
A new approach using artificial intelligence and electronic health records is being developed to create a fairer, more effective billing model for telehealth services. The current time-based billing model undervalues experienced doctors' expertise and time, leading to inequities in compensation.
A study led by University of Cincinnati researcher Jun-Ming Zhang investigates the link between blood vessel movement and neuropathic spontaneous pain. The research aims to understand how blood vessel movement triggers cluster firing of neurons, a key mechanism in neuropathic pain.
Researchers found that mosquitoes drink blood to survive droughts, not just water, allowing them to bite more frequently when rain comes. This increases the risk of spreading diseases like malaria, dengue fever, and Zika during dry periods.
Researchers are pinpointing areas of high overdose frequency to implement targeted interventions, including naloxone kits and fentanyl test strips. The study aims to reduce overdose deaths and improve access to life-saving resources in underserved communities.
A University of Cincinnati Cancer Center study identifies microRNA miR-205 as a promising new target to overcome breast cancer treatment resistance and improve outcomes. The research found that boosting levels of miR-205 could block the production of MED1, a protein responsible for treatment resistance, and improve treatment outcomes.
Researchers found that delivering at 39 weeks provides the optimal balance between stillbirth risk and infant health issues, making it an ideal time frame for safest births. The study used a large-scale data set to provide evidence-driven recommendations for delivery timing among women with chronic hypertension.
Researchers have identified a promising new drug, lomonitinib, targeting treatment-resistant acute myeloid leukemia (AML) with FLT-3 mutation. Additionally, they developed a novel compound to target MALT1 protein in chronic lymphocytic leukemia (CLL), aiming to provide better control of the disease.
The University of Cincinnati College of Medicine has launched a styrofoam recycling project to divert over 900 pounds of EPS waste from landfills each month. The program aims to reuse existing styrofoam materials, reducing the need for styrene and minimizing environmental impact.
A pilot clinical trial is testing the effectiveness of noninvasive electrical brain stimulation as a cognitive rehabilitation method for traumatic brain injury (TBI). The study aims to determine how early treatment with targeted brain stimulation can enhance cognitive recovery in moderate to severe TBI.
Neutrino research may hold the key to understanding the universe's origins and the imbalance between matter and antimatter. Scientists are exploring experimental anomalies and searching for a new 'sterile' neutrino flavor, which could provide answers to these deep questions.
Researchers have created a method to track genetically modified immune cells using PET scans, providing real-time insights into their behavior and persistence in solid tumors. This technology has the potential to inform personalized treatment options and optimize therapy regimens.
A new wireless EKG patch developed by MG Medical Products has been shown to be as accurate as traditional EKG machines in a recent University of Cincinnati study. The patch eliminates electrode misplacement errors and reduces hospital readmission rates, particularly in skilled nursing facilities and correctional institutions.
University of Cincinnati researchers highlight the importance of emergency consent in acute stroke trials due to time-sensitive nature and high mortality rate. They argue for more efficient alternatives to traditional informed consent, emphasizing patient autonomy and beneficence.
A new University of Cincinnati Cancer Center study reveals how copper helps clear cell renal cell carcinoma cells grow and advance. Copper accumulation is associated with worse outcomes for patients with ccRCC, and it boosts energy and growth in cancer cells.
Researchers have found that Burmese pythons can swallow deer and other large prey whole, with a gape circumference of over 81 centimeters. This increased capacity could lead to a significant impact on native wildlife populations in Florida and potentially beyond.
The University of Cincinnati is launching a new climate change health research center, focusing on vulnerable populations and extreme heat exposure. The center aims to reduce risks for people, especially in economically disadvantaged urban areas.
The study aims to examine how racism, housing instability, screen time and stress affect young children's sleep. Most healthy adults need at least seven hours of sleep nightly, but young children require more: Infants need 12-16 hours with naps, while toddlers and preschoolers need 11-13 hours.
Researchers identified AM-101 as a potential new way to enhance radiation therapy for patients with lung cancer that has spread to the brain. The drug's ability to activate GABA(A) receptors increases autophagy in lung cancer cells, making them more sensitive to radiation treatment.
An interdisciplinary study found associations between exposure to environmental phenols like BPA and triclocarban and altered cardiac electrical activity, particularly in women with higher body mass indexes. Researchers identified moderate changes to cardiac electrical activity that could exacerbate existing heart disease or arrhythmias.
Shailaja Paik, a University of Cincinnati professor, has been awarded a MacArthur fellowship for her groundbreaking research on Dalits and caste inequality in India. The grant will support her work on promoting education and human rights for marginalized communities.
Researchers created an artificial blood vessel model using 3D bioprinting to test new therapies for glioblastoma. This device enables the creation of personalized disease models, potentially improving patient survival rates.
Researchers will conduct laboratory and field work at UC Medical Center to detect airborne transmission of MRSA. The study aims to better understand the significance of airborne transmission of MRSA and inform enhanced workplace safety measures.
A study published in the journal Brain shows that increases in protein levels with new Alzheimer's drugs can explain the slowing of cognitive impairment at least as well as the reduction in amyloid plaques. The researchers found that higher levels of a critical brain protein correlate equally well with cognitive benefits.
Researchers have found a potential compound that pairs well with an IRAK4 inhibitor to kill AML cells by reducing c-Myc levels, a protein also driving cancer growth. The three-year LLS grant will allow further research into the effects of IRAK4 targeting on c-Myc.
A new AI tool called CAR-E is being developed to provide personalized coaching conversations for medical students and residents, encouraging reflective practice and enhancing their skills. The web-based tool will use a coaching approach to prompt students to think back on their clinical encounters and knowledge gaps.
Researchers have developed a new method to increase speed and success rates in drug discovery by combining data from the Library of Integrated Network-based Cellular Signatures with targeted docking simulations. This approach can accelerate the drug research process, identifying potentially effective compounds more efficiently.
Researchers at the University of Cincinnati are developing a new technology using magnetic nanoparticles to deliver medications directly to the inner ear, where hearing loss occurs. The goal is to create an effective and minimally invasive treatment option for various types of hearing loss.
Researchers found that blind cavefish develop more taste buds on their head and chin, particularly after 18 months of age. This adaptation is thought to be an adaptive trait, allowing the fish to better detect food sources like bat guano.