Researchers at University of Arizona Health Sciences identified a potential way to reduce female post-operative pain by inhibiting pituitary prolactin. Stress can increase circulating levels of prolactin, leading to worsened post-operative pain in women.
A study led by Johns Hopkins Medicine found a genetic mutation, F722fs, in the MMS22L gene that is associated with a higher risk of prostate cancer. The researchers identified this mutation in Ashkenazi Jewish men and found it was linked to increased sensitivity to a specific anticancer therapy.
Acoustic metamaterial enables pushing, rotating, and complex movements in 3D. Researchers can now move and position objects underwater without touching them directly, paving the way for applications like remote surgery and drug delivery.
A new liquid biopsy blood test called HPV-DeepSeek achieved 99% sensitivity and specificity for diagnosing cancer in asymptomatic patients. The test detected fragments of the viral genome and other features in the blood, outperforming current methods in detecting HPV-associated head and neck cancers.
The Center for Research Innovation in Biotechnology (CRIB) has developed a comprehensive database of active pharmaceutical ingredients with evidence of clinical testing. The database provides valuable information on drug discovery and development, including pricing, sponsors, and intended clinical applications.
Researchers at Nagoya University developed an interface that creates programmable electric fields to sort graphene oxide without fixed microfluidic devices. The findings allow precise sorting of GO sheets, which can capture pollutants, solvents, and biomolecules based on their size-dependent properties.
A team of researchers at Baylor College of Medicine identified six flavonoids that kill bladder cancer cells, including compounds that cause DNA damage and disrupt energy supply. The study uses Cell Painting technology to analyze large-scale drug screening data sets on a standard desktop computer.
Researchers at Forschungszentrum Jülich have discovered a property of crystal structure called chirality that influences the orbital angular momentum of electrons. This could lead to a new class of electronic components capable of transmitting information with exceptional robustness and energy efficiency.
DeepSeek-R1 has been shown to enhance clinical workflows, supporting diagnostic reasoning, treatment planning, and risk assessment. The model has also demonstrated promise in patient engagement and medical education, improving patient adherence and creating interactive educational cases.
A new method called MagIC cryo-EM dramatically improves imaging capabilities by reducing sample loss, enabling the visualization of rare proteins and viruses. The technology also addresses the challenge of handling small proteins, allowing for more accurate structural analysis.
A Geisinger study finds that Y chromosome genes increase height by 3.1 centimeters in individuals with sex chromosome aneuploidy, explaining approximately 23% of the average height difference between men and women.
Researchers discovered that platelet-activating factor (PAF) triggers strong contractions in the esophagus and upper stomach, potentially linked to food allergies and acid reflux. PAF also causes rhythmic muscle movements in the colon, which may be connected to chronic digestive diseases.
A two-year study found that fluridone is effective in controlling Palmer pigweed in rice, but its use can cause injury to some cultivars. Rice farmers should apply the herbicide before the three-leaf stage and follow the label instructions to minimize risk.
A study by Kobe University reveals that plants reproducing solely through self-pollination likely arose from populations with extremely low genetic diversity. The research found that these species are highly successful at producing fruit and may have an evolutionary edge over outcrossing, raising questions about their long-term viability.
Christopher Kane's appointment as ABU president reflects his commitment to excellence in patient care, groundbreaking research, and physician mentorship. As president, he will refine certification protocols and enhance the urologist experience.
Wuhan University has developed a comprehensive digital transformation framework emphasizing tiered training for DI talent and integrating DI elements into discipline development. The framework aims to develop general knowledge-equipped, application-oriented, and professional talents.
A new study suggests that limiting global temperature increase to 1.5°C may not be enough to save the world's ice sheets, which could lead to significant losses and extensive displacement of coastal populations. The researchers argue that a target of around 1°C would be more effective in preventing rapid sea level rise.
A protein complex has been identified that repairs abnormal DNA responsible for neurodegenerative disease Huntington's. This discovery could lead to the development of a therapeutic target to delay or prevent disease onset.
A research team has pinpointed the genetic location behind thorns in blackberries, enabling plant breeders to accelerate the creation of thornless varieties. The study used genome-wide association studies and genotyping to identify a specific region of DNA associated with the prickly trait.
The Lancet Commission warns that over 1 billion adolescents worldwide face preventable health problems, with inadequate progress in addressing issues like anaemia, mental health, and obesity. The commission emphasizes the need for increased investment in adolescent health and wellbeing initiatives to safeguard the future.
A new study by Queen Mary University of London found significant ethnic differences in breast cancer development and outcomes among women of African and South Asian genetic ancestry. Women from these backgrounds were diagnosed earlier and died younger than European-ancestry women, highlighting the need for tailored care approaches.
Surgeons at Mount Sinai performed the world's first heart-liver-kidney triple organ transplants in New York State, with two patients making full recoveries after the surgeries. The procedures were led by Anelechi Anyanwu and Sander S. Florman and represent a significant milestone in complex organ transplantation.
A new computational model shows that structural inequalities, including wealth inequality and social segregation, accelerate the spread of infectious diseases through society. In a hypothetical 'ideal' scenario without segregation, infection rates were lower in most metropolitan areas.
Researchers found that aging impairs CAR-T cell function and antitumor activity due to lower NAD levels. Rejuvenating aged cells with NAD-boosting compounds improves their effectiveness.
The magnetic shaftless propeller-like millirobot (MSPM) integrates multimodal motion and fluid manipulation, breaking through limitations of existing magnetic miniature robots. It achieves multiple adaptive motion modes, including rolling, propelling, and tumbling, in different terrains.
Research found that women whose sister experienced postpartum psychosis are over 10 times more likely to experience it themselves. The study highlights genetic and shared environmental influences and suggests early recognition and prevention are crucial.
A study found a decline in new dementia cases in the US from 2015 to 2021, but an increase in those living with the condition. The incidence of dementia decreased among older adults, while prevalence increased, highlighting disparities by race and socioeconomic status.
A team from The University of Osaka has developed an efficient non-precious metal catalyst for converting biomass-derived furfural to tetrahydrofurfuryl compounds, achieving high yields under mild conditions.
Researchers identified poly-metabolite scores in blood and urine associated with ultra-processed food consumption, providing an objective measure of UPF intake. The study found hundreds of metabolites linked to energy from UPFs, enabling the creation of a score predictive of diet quality.
Researchers discover CGMMV uses host cytosolic fructose-1,6-bisphosphatase to form membraneless subcellular compartments, promoting viral replication and particle assembly. A novel compound inhibits this process, providing a promising antiviral strategy.
A new study from Kennedy Krieger Institute reveals nearly 40% of pediatric patients with long COVID report significant symptoms of anxiety or depression. The study highlights the importance of integrating mental health screening into care for children with long COVID to improve quality of life.
A UNSW-led study reveals humpback whales are giving birth up to 1500 km north of their previously assumed calving zone in Tasmania. This challenges current beliefs and raises concerns about the vulnerability of newborn whales exposed to risks like boat strikes, entanglements, and pollution.
Dr. Miriam Merad has been recognized for her groundbreaking research on macrophage biology and immunology, with a focus on cancer and chronic inflammatory disease. Her work has led to the development of novel therapeutic targets and has improved treatment outcomes for patients with lung cancer.
Researchers have identified two new species of crayfish in the Pacific Northwest, but their discovery also highlights the risk of extinction due to invasive species. The Okanagan Crayfish and Misfortunate Crayfish have been named after their native habitat and unfortunate fate.
Researchers found that digital detox interventions on TikTok led to increased usage among users who were less skeptical of advertising, viewing the platform as more authentic. In contrast, users with higher skepticism showed no significant change in behavior. The study highlights the potential backfire effects of well-intentioned effor...
A new study published at the ATS 2025 International Conference suggests that standard screening tests may misclassify delirium status in Spanish-speaking ICU patients. A newly developed Spanish-language screening tool called Spanish-FAM outperforms conventional practices and reduces disparities in care.
Terrence Sejnowski has been elected to the Royal Society and the American Philosophical Society, a testament to his groundbreaking contributions to computational neuroscience. His pioneering work includes inventing the Boltzmann machine and NETtalk program, which revolutionized artificial neural networks and speech recognition.
A new study published in ECNU Review of Education highlights the effectiveness of school-to-school collaboration in improving student academic performance, particularly in underperforming schools. Structured collaboration, peer relationships, and principal leadership contribute to enhanced learning outcomes.
Researchers at Kyoto University have developed a new non-invasive diagnostic method for insulinomas, which achieved 100% diagnostic accuracy in a Phase II clinical trial. The new method using positron emission tomography (PET) probe successfully detected cases difficult to diagnose through existing methods.
The American Heart Association has awarded nearly $1.2 million in planning grants to 12 researchers testing the efficacy of food is medicine interventions, such as produce prescriptions and medically tailored groceries. The grants support clinical trial protocols to develop and test these approaches for treating chronic diseases like c...
The application of AI in public health informatics offers potential to revolutionize data collection, disease surveillance, decision-making, and interventions. However, its implementation faces technical, ethical, and operational challenges related to health equity, privacy, security, and bias.
Researchers have synthesized cutting-edge findings on Prader-Willi syndrome, revealing its unique link to autism spectrum disorder and psychotic spectrum disorders. The condition's distinct genetic subtypes correlate with specific psychiatric outcomes, offering critical insights into the interplay between genetics and psychiatric vulne...
Scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A exposure. The research found that specific tRNA fragments interact with key proteins and RNA molecules involved in regulating ferroptosis, supporting neuronal survival by blocking cell death pathways.
Research reveals that ignoring ecological differences between male and female plants can lead to inaccurate biodiversity forecasts. The study highlights the need to refine biodiversity forecasts to account for sex-specific responses to climate change, finding that female dominance may increase under global warming.
Researchers found that bacteria trapped in the implant's internal cover screw during surgery dominate early colonization and influence later arrivals. The findings suggest a critical window for interventions to prevent peri-implantitis, a major cause of dental implant failure.
Researchers at The University of Osaka found that localized oxygen deficiency in colon tumors can promote tumor growth by transforming normal fibroblasts into inflammatory fibroblasts. These altered cells release factors that help tumors grow, offering a potential new target for cancer therapy.
Researchers at VIB-KU Leuven have identified a novel protein complex that regulates the formation of spine apparatus in developing synapses, essential for stabilizing mature synapses and supporting learning and memory. The study reveals that GPR158 interacts with PLCXD2 to control spine apparatus abundance, lifting the brake on synapti...
Researchers have identified promising material platforms and pathways to create Z3 parafermions, enabling Fibonacci anyonic statistics and universal topological quantum computation. High-filling states and coupling FQAHE with superconductivity are potential approaches.
Research from Babraham Institute uncovers importance of RNA binding proteins in regulatory T cell function. The study sheds light on how the immune system maintains balance and forms foundation for understanding age-related inflammation.
The AI-driven Distributed Acoustic Sensing (DAS) system leverages narrow-linewidth lasers for real-time acoustic wave propagation information. Data acquisition, preprocessing, and machine learning model construction are key stages in this technology.
Scientists create ferritin structures with precisely arranged histidine residues to drive oxidation reactions in a highly effective metal-free peroxidase. This approach eliminates the need for metal cofactors and enhances catalytic activity.
UT Dallas bioengineers have created an enhanced light-activated immunotherapy approach to target advanced stomach cancer. Lab-designed molecules are primed with far-red or near-infrared light to activate the immune system against stubborn cancer cells, reducing side effects.
A new study by Brown University researchers used machine learning to analyze a massive dataset of slope streak features on Mars, finding no evidence of liquid water. The research suggests that the streaks are likely formed by dry processes such as wind and dust activity, rather than liquid flow.
Antonios Mikos, a leading expert in biomaterials and tissue engineering, has been elected to the European Academy of Sciences. He is recognized for his groundbreaking work in regenerative medicine, controlled drug delivery, gene therapy, and disease modeling.
Researchers investigate how increased warm, salty offshore water affects the cold pool on the continental shelf. Salinity measurements reveal seasonal salinification of the cold pool, shedding light on coastal ecosystem conditions.
A study of 1,113 patients aged 65+ found that nearly half had two or three overlapping cardiovascular, kidney, and metabolic conditions, leading to poorer physical function and higher mortality rates. The findings support the need for early identification of vulnerable individuals and risk stratification without advanced diagnostics.
A global study assesses ecosystem service supply-demand trends from 2000 to 2020, revealing complex patterns of surplus and deficit. The findings highlight the need for targeted land-use strategies to address regional mismatches in services such as food production, carbon sequestration, and water yield.
Researchers found that prolonged exposure to N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ) disrupts lipid and carbohydrate metabolism, causes liver injury, and alters behavioral patterns in zebrafish. The study suggests that transformation products may pose even greater risks.
A new study finds that nano-encapsulated pesticides have dramatically lower environmental risks than conventional formulations, reducing freshwater ecotoxicity impact scores by up to five orders of magnitude. This breakthrough highlights the importance of life-cycle assessments in developing safer agrochemicals.
The ETH Zurich researchers have developed SonoTextiles, a novel technology that uses acoustic waves to measure touch, pressure, and movement in fabrics. This allows for accurate health monitoring, such as tracking breathing patterns, with minimal power consumption and high precision.