Researchers found four anti-cancer drugs that enhance penicillin-type antibiotics' effectiveness against MRSA, while one drug reduced effectiveness. The discovery may lead to combination therapies pairing antibiotics with non-antibiotic drugs to extend existing antibiotics' lifespan and provide new treatment options.
Researchers from University of Galway developed an AI accelerated computational model to investigate the theory behind why physical forces slow cancer growth. The study suggests that harnessing pressure on a tumor could open new roles for treatments known as mechanotherapies.
Researchers at University of Galway discovered a new therapeutic approach to combat Alzheimer's disease. They found that stimulating the brain's efficiency and balance may help alleviate cognitive decline and memory impairment. By blocking the activity of GABA receptors, they can reverse Alzheimer-like effects and improve cognitive per...
Researchers have discovered a second planet, WISPIT 2c, in the same system as the previously detected WISPIT 2b, which is estimated to be about 5 million years-old and has a mass ten times that of Jupiter. The young gas giant was detected using the European Southern Observatory's Very Large Telescope Interferometer.
Researchers discovered diverse microbes on coral reefs, producing chemicals with promising applications in medicine and biotechnology. The findings highlight a critical dimension of conservation: the loss of coral reefs also loses a vast 'molecular library' linked to microbial life.
New research reveals that burning 'low smoke' manufactured fuels releases tiny ultrafine particles, potentially harming human health. The study highlights the urgent need to revise air quality standards and reduce residential solid fuel burning as part of efforts to decarbonize the economy.
Researchers pinpoint high-risk areas for deadly scorpion species using field observations and computer modeling. The study's findings focus on central Morocco, a global hotspot for scorpion stings, but can be applied globally to prevent deaths and improve treatment.
A new study by University of Galway researchers highlights satellites' unique role in climate adaptation, providing objective and repeatable measurements spanning up to 60 years. The research demonstrates how satellite data can inform adaptation tracking across multiple sectors, supporting the Paris Agreement's Global Goal on Adaptation.
Research analyzing over half a million social media posts found that charismatic animals like cats and hippos generated the highest engagement. Meanwhile, plants, which comprise 57% of endangered species, received disproportionately limited attention in online discourse.
Researchers at the University of Galway have discovered that structural stromal cells in bowel cancer can 'switch off' the immune system and how targeting these cells could reactivate natural killer cells to fight cancer. The study's findings have significant implications for immunotherapy treatment.
A new study found that entering menopause at an earlier age is associated with a higher risk of dementia. On the other hand, post-menopause hormone replacement therapy appears to lower the risk of dementia. The research involved over 1,300 women from the Framingham Heart Study and analyzed various factors related to brain aging.
Researchers analyzed over 1,700 Instagram photos to track the invasive Carpobrotus species, finding that its populations flower longer than native ones in invaded regions. This reproductive advantage may help explain their invasive success, and the findings offer practical guidance for coastal managers.
Researchers detected a new planet, WISPIT 2b, at an early stage of formation around a young analog of our Sun, estimated to be about 5 million years-old. The discovery provides valuable insights into planet-disk interaction and subsequent evolution.
A new study warns that Ireland's proposed climate targets prioritize methane emission privileges for wealthy nations over poorer countries' development, undermining the transition to a sustainable and equitable food system. This approach could lock-in current inequalities in the global food system by reducing the need to curtail or off...
Researchers have discovered a likely site of a new planet in formation using the European Southern Observatory's VLT. The disk, which extends 130 astronomical units from its parent star, shows a bright ring and spiral arms.
Researchers found that spider venoms are prey-specific, meaning they target the physiology of animals found in their natural diet. This explains why some spiders, like the Brazilian wandering spider, have potent venom, while others, like the Giant house spider, have less effective venom.
Undergraduate students at University of Galway lead a major study on the link between diabetes medications and dementia risk. The research found that GLP-1 receptor agonists may have a protective effect on brain health, reducing the risk of developing dementia.
A research team used earth observation radar data to map the impact of oil pipeline networks on mangroves in the Niger Delta, finding a mortality rate of 5,644 hectares per year. The study highlights specific locations needing immediate intervention and restoration, and identifies new pipeline sites with unreported oil spill damage.
The team created APOLLO, a collection of 247,092 advanced computer models, each representing the unique metabolic processes of a distinct microbe found within these communities. The unprecedented database will allow scientists to study how microbes function within the human body and interact with health and disease.
Researchers at University of Galway have made a breakthrough in bioprinting functional human heart tissue that can change shape, bringing research closer to generating fully functional organs. The technology has shown improved structural and functional maturity of bioprinted heart tissues.
Researchers at the University of Galway and the University of Limerick have discovered that electrical stimulation can help maintain healthy tendons. The study used a novel cell culture device to deliver mechanical vibrations and electrical stimuli, causing cells to better retain their healthy properties and promoting tendon regeneration.
Research from a global study co-led by University of Galway found that frequent drinking of fizzy drinks or fruit juice increases the risk of stroke. Drinking more than four cups of coffee per day also raises this risk. The study advises avoiding or minimizing fizzy and fruit drinks, and switching to water instead.
A new technology allows for rapid and accurate detection of Shiga toxin-producing Escherichia coli in water sources, enabling Environmental Health Officers and groundwater schemes to test more frequently. The portable device provides on-the-spot results in under an hour, helping to prevent outbreaks of infection.
Scientists at University of Galway create advanced computer models simulating newborn and infant metabolism. The digital babies can be personalized, enabling researchers to investigate individual infants' metabolism for precision medicine applications.
A novel computational model simulating shear stress distribution in the colon with varying mucus thicknesses reveals how mucus acts as a lubricant, significantly increasing faecal velocity and easing waste movement. The study highlights the protective function of mucus shielding delicate cells from mechanical forces.
A new approach to heart bypass surgery has been successfully tested, using non-invasive cardiac-CT scan images and AI-powered blood flow analysis. The trial showed a 99.1% feasibility rate, indicating that the procedure is safe and effective without invasive diagnostic catheterisation.
Researchers at the University of Galway have developed a new method for improving stem cell-based brain repair therapy for Parkinson's disease, which shows promising results in enhancing survival and maturation of cells in the brain. The technique uses a collagen hydrogel to support and protect the cells after transplantation.
A team of international astronomers has captured stunning images of over 80 young stars and planetary discs using the ESO's VLT. The research provides a wealth of data on planet formation, revealing diverse populations of planets and planetary nurseries across three star-forming regions in the Milky Way galaxy.
Researchers found a higher risk of heart disease or stroke among patients who stopped taking aspirin, but no significant difference in major bleeding risk. The study suggests that patients already safely taking aspirin may continue to benefit from its use without increased risk.
Researchers have discovered that brain cells sense continuous motion caused by everyday bodily functions, leading to friction and inflammation around implanted devices. Anti-inflammation approaches, such as coating implants with soft gels, could help prevent damage and increase device lifespan.
Researchers at CÚRAM have published a study revealing the interconnectedness of cellular components. The work uses SRS microscopy to track multiple cell processes simultaneously, offering insights into disease behavior and potential improvements in drug treatments.
A new clinical trial has found that administering metformin to pregnant women with gestational diabetes does not increase adverse neonatal outcomes or maternal health risks. The study provides hope for expectant mothers and healthcare providers seeking a safe alternative to traditional insulin-based treatments.
Researchers at University of Galway and MIT have developed an intelligent implantable device that can sense its environment, adapt to release drugs as required, and bypass scar tissue buildup. The device uses AI to tailor drug delivery to individual patients, reducing fibrotic encapsulation and ensuring consistent dosing.
A new study reveals that domestic firelighters emit more black carbon than all biomass fuels combined, posing a significant threat to air quality and climate change. The research found that even small quantities of firelighter use can have devastating effects on human health and the environment.
Researchers have identified a novel approach to enhance anti-tumor immunity in bowel cancer by targeting sugar-coated molecules called sialoglycans on tumor-associated stromal cells. This strategy has shown promise in reversing T-cell mediated immunosuppression and improving treatment outcomes.
A global study led by the University of Galway found that sleep problems, including snoring and sleep apnea, can increase the likelihood of having a stroke. The study identified six sleep behaviors associated with an increased risk of stroke.
Researchers at University of Galway discovered that individuals experiencing depression symptoms are more likely to suffer acute strokes and experience poor recovery outcomes. The INTERSTROKE study, involving 26,877 adults across 32 countries, revealed a significant link between depressive symptoms and stroke risk.
Researchers created a novel pre-clinical model of non-ST elevation myocardial infarction (NSTEMI), which closely resembles clinical cases in humans. The model can aid in developing targeted pharmacological solutions to correct tissue changes associated with NSTEMI.
Scientists at University of Galway have discovered that the noble false widow spider feeds on the endangered pygmy shrew. The study highlights the invasive spider's potent venom and complex hunting behavior, raising concerns about its impact on native species in Ireland and Britain.
A global study involving 5,869 patients from 50 countries found that 35% could not be successfully weaned from invasive mechanical ventilation. Researchers recommend a systematic approach to reduce weaning duration and improve survival rates, with higher sedation levels associated with delays in initiating weaning.
Researchers at University of Galway have created a digital microbe database, AGORA2, which enables computer simulations of how drug treatments work and how patients respond. The resource offers personalized predictions of differences in metabolism between individuals for diseases such as Parkinson’s and colorectal cancer.
Researchers at University of Galway outline a potential new treatment option for MRSA infections using purine nucleosides. The study shows that these sugar versions of DNA building blocks can interfere with bacterial signaling systems, making bacteria more susceptible to penicillin-type antibiotics.
A collaborative study between University of Galway and Brunel University London found that patients with severe obesity respond differently to a dietary weight loss programme based on their genes. The research identified a
A recent University of Galway-led study found that psychosocial stress increases the risk of stroke by 17%, with severe work stress being a significant contributor. The research also revealed that individuals who reported feeling more in control had lower stroke risks.
Researchers discovered a microRNA biomarker, miR-145, can predict which breast cancer patients are at high risk of recurrence and death. This finding has the potential to identify tailored treatment options for these patients.
Researchers at CÚRAM developed an interdisciplinary framework to characterize ECM-based hydrogels, providing a concise guide for chemists, material scientists, and biologists. The review aims to bridge the gap between material science and biomedicine, facilitating further interdisciplinary work to create solutions for chronic illnesses.
A global study found that high and moderate alcohol consumption is associated with increased odds of stroke, while low-level drinking has no link. The INTERSTROKE research involved almost 26,000 people worldwide and explored the role of alcohol intake in stroke risk, revealing complex associations with socioeconomic factors.
A new treatment approach for triple-negative breast cancer is being developed using nitric oxide scavengers. The study found that converting nitric oxide into nitrogen centred free radicals inhibits the migration of cancer cells in the tumor environment, suggesting a potential use of modified hyaluronic acid as a key material.
A global ICU study has identified propofol, a commonly used anaesthetic drug, as a major risk factor for cardiovascular complications in critically ill patients. The study found that propofol increases the risk of cardiac arrest and severe hypotension after intubation.
A new international study has identified the most critical vascular risk factors for dementia, highlighting the importance of controlling high blood pressure and diabetes. The research, led by Professor Emer McGrath, found that individuals with these conditions are four times more likely to develop dementia than those without them.