Researchers have developed a monolithically integrated VCSEL technology achieving linewidth compression to approximately 1 MHz, enabling stable single-mode operation for precision applications. The device demonstrated impressive performance in a cesium vapor-cell atomic clock, with a frequency stability of 1.89×10^−12 τ^−1 /^2.
A new study proposes that the brain's reward system is built to optimize energy, not pleasure. Researchers argue that dopamine and opioids function as physiological agents to manage the body's energetic budget, guiding behavior and learning.
This study reveals the regulatory role of BCAT2-mediated BCAA catabolism in VSMCs and its impact on intraplaque calcification in diabetic atherosclerosis. BCAT2 deficiency attenuates vascular calcification severity, decreases calcium salt deposition, and suppresses osteogenic phenotypic transition of VSMCs.
Scientists in China have designed MOFs with 3D pyr-topology frameworks and polyhedral cages to efficiently purify methane from natural gas. The materials exhibit high adsorption capacities for C3H8 and C2H6 but extremely low CH4 uptake.
This study presents a polyhydroxy hydrogel electrolyte with in situ regulated interface chemistry suitable for biosensing-compatible zinc batteries, achieving unprecedented cycling stability and high-performance biosensing. The hydrogel electrolyte enables a conformal and continuous interface, promoting uniform ion transport and deposi...
Researchers at Tufts University and Wyss Institute created neurobots by adding nerve cells to tiny living forms called xenobots, which exhibit complex movements with simple neural networks. The resulting neurobots display unique behaviors and demonstrate the formation of primitive nervous systems.
A research team from NUS has shown that compounds extracted from red dragon fruit peel can be incorporated into bread to increase antioxidant activity and slow starch digestion, offering a potential pathway to healthier staple foods and reduced food waste. The study found that optimal fortification levels of 0.75 per cent improve dough...
A phase 3 clinical trial found romiplostim significantly reduced chemotherapy dose delays and improved platelet counts in patients with gastrointestinal cancers who developed persistent low platelet counts during treatment. The therapy enables patients to maintain chemotherapy intensity, potentially preserving the integrity of cancer c...
Aging silicon-rich biochar reduces cadmium uptake in leafy vegetables, improving plant resistance to heavy metal stress. The material reshapes soil microbial communities, contributing to reduced cadmium availability.
Researchers have presented a new design paradigm for 2D flash memory devices using monolayer Janus MoSSe, achieving ultrafast charge trapping and superior retention. The device exhibits high-speed program/erase operations, stable data retention exceeding 10^8 seconds, and energy efficiency with reduced operating voltages.
Researchers develop oxychar, a highly efficient, budget-friendly alternative to traditional charred organic materials for toxic cadmium removal. The new material soaks up both agricultural ammonia and cadmium, promising a practical win for sustainable farming.
A Japanese registry study reveals widespread underdiagnosis and undertreatment of metabolic acidosis in chronic kidney disease patients. Nearly half of patients with bicarbonate measured had metabolic acidosis, and diagnosis and treatment rates were low, highlighting a need for routine bicarbonate testing in CKD care.
Researchers identified key health indicators for a new global system to monitor people's health before pregnancy. The study found that mental health, physical health, supportive relationships, and finances are prioritized by both healthcare professionals and the general public.
A new study published in The Lancet reveals that fathers' health and well-being play a significant role in shaping pregnancy and child outcomes. The research emphasizes the importance of investing in the well-being of boys and young men to reduce health disparities and improve outcomes for future generations.
A comprehensive review of 54 randomized controlled trials found no evidence that medicinal cannabis is effective in treating anxiety, depression, or PTSD. However, the study suggests that medicinal cannabis may be beneficial for certain conditions, such as reducing seizures associated with epilepsy and managing pain.
A new study models the impact of climate change on physical activity globally, predicting millions will be driven into inactivity by 2050. The study suggests this could lead to hundreds of thousands of premature deaths and billions of dollars in lost productivity.
Researchers found that bull sharks have active social preferences and choose their social partners, similar to humans. The study revealed that adult sharks form the core of the social network, while younger sharks are less socially connected.
A new study found that climate action consistent with the two-degree-Celsius target would avoid more than 13.5 million premature deaths from air pollution between 2020 and 2050, mostly in low- and middle-income countries. However, the distribution of health gains depends on how the global mitigation burden is shared.
The integration of artificial intelligence is changing environmental research, enabling scientists to connect massive datasets, uncover patterns, and generate predictive insights. AI-powered approaches can help better understand environmental processes across different spatial and temporal scales, leading to more accurate forecasting a...
A new app developed by Iowa State University researchers and global partners aims to provide farmers with instant identification and practical advice on how to manage pest, weed, and disease issues effectively. The app's artificial intelligence system will be trained on millions of images and data points to make accurate identifications.
Researchers from Southeast University and Nanjing Normal University create supercapacitor technology using plant waste, enabling rapid-charging energy storage at 4.0 volts. The innovative approach combines a custom electrode with a specialized electrolyte to stabilize the system.
The American College of Physicians (ACP) supports the American Academy of Pediatrics' (AAP) 2026 childhood vaccine schedule, which is based on evidence and better reflects current disease epidemiology. The ACP's Immunization Committee found the AAP recommendations to be more evidence-based than the CDC's recommendations, particularly i...
Researchers at the University of Arizona ran simulations to predict how a large crater near Psyche's north pole could have formed, shedding light on its composition. The study found that porosity plays a significant role in crater formation, with implications for understanding Psyche's makeup.
Researchers found that patients with both conditions exhibited different neuropsychiatric symptoms, which could inform diagnosis and treatment plans. The study's findings may help clinicians better understand the complex disease course of patients with multiple disorders, including Alzheimer's and frontotemporal lobar degeneration.
Researchers discovered that changes in breathing patterns, specifically strong abdominal muscle contractions during exhalation, can trigger hypertension. Targeting neurons in the lateral parafacial region, a potential therapeutic approach to treat hypertension has been identified.
A new biochar-enhanced photocatalyst has been developed to efficiently degrade antibiotic contaminants in water, with the material demonstrating remarkable ability to break down sulfadiazine. The photocatalyst harnesses sunlight to drive chemical reactions capable of degrading antibiotic molecules, and its performance is substantially ...
A new pediatric mental health care model, P2C3, combines primary care and psychiatry to improve access and training for future pediatricians. The model, which has completed over 1,500 visits and cared for over 400 patients, has shown durable and scalable results, reducing fragmentation and providing timely access to mental health care.
A new study of 462 college students in the University of Hawai’i system found that half of Native Hawaiian students experience period poverty, with significant mental health and academic consequences. The findings also highlight unequal outcomes based on race and socioeconomic status.
A new study suggests that early life stress during pregnancy and early childhood can lead to long-term digestive issues, including gut pain and motility challenges. The research found that early life stress can shape the development of gut-brain communication, contributing to gastrointestinal symptoms in both mice and humans.
The American College of Cardiology will host the New Orleans Health Fair on March 21, 2026, offering free screenings, health education, and early detection for cardiovascular diseases. The event aims to improve community heart health and provide equitable care.
Researchers found that early adult drinking combined with stress leads to cognitive decline in middle age, with brains damaged beyond recovery. Heavy drinking rewires the brain's circuitry, impairing decision-making and increasing risk of dementia and Alzheimer's disease.
Researchers at Colorado State University have identified four Fusarium species causing potato dry rot in the San Luis Valley, including one not previously found in the US. This study will help improve disease diagnosis and monitoring, as well as guide cultivar selection and breeding for disease resistance.
BRIGHT at DTU joins forces with Novonesis to develop microbes that can efficiently utilize acetic acid produced from captured carbon, enabling the production of sustainable protein. The collaboration aims to accelerate microbial fermentation and reduce costs, ultimately contributing to a circular bioeconomy.
Researchers at Rice University explored how artificial intelligence and machine learning can accelerate discoveries in the Deep Underground Neutrino Experiment (DUNE). The workshop aimed to integrate AI techniques into the massive computing ecosystem powering the experiment.
Using a computational model, neuroscientists at MIT showed how the brain selectively focuses attention on one voice among others in a noisy environment. The model found that amplifying the activity of neural processing units that respond to features of a target voice allows that voice to be boosted to the forefront of attention.
A team of researchers from the University of Mississippi has created a customizable wound scaffold that delivers natural antibacterials to encourage healing. The 3D-printed bandage is made from biodegradable materials that reduce the chance of infection and can be tailored to fit any wound.
Researchers have identified a distinct gene expression program associated with neurotransmission in the living human brain. The study combines molecular data with real-time physiological recordings, revealing a coordinated set of genes whose activity tracks with neuronal signaling.
A 37-year study by the Smithsonian Environmental Research Center found that cannibalism is the primary killer of juvenile blue crabs in mid-salinity waters. However, young crabs can escape predation by migrating to shallow waters, where they are safer from adult crabs and other predators.
A crisis communication study reveals Ticketmaster's inadequate response to technical failures and public backlash, leading to a political scandal and antitrust lawsuit. The company's lack of transparency, avoidance of responsibility, and failure to issue a full apology further damaged its reputation.
The Small Magellanic Cloud's stars do not orbit around its center due to a direct collision with the Large Magellanic Cloud. The collision disrupted the SMC's internal structure and destroyed its gas rotation, making it a unique case to study galaxy evolution.
The ARU Arm AI Lab will provide researchers and students with access to advanced Arm AI technology, focusing on real-world applications in healthcare and life sciences. This partnership will also support emerging talent and drive innovation, building on existing collaborations and industry projects.
Photorespiration provides carbon atoms required for environmentally induced DNA modification, influencing plant adaptation to environmental influences. The study found a metabolic connection between photorespiration and epigenetic regulation, suggesting a new approach to optimize crop strategies.
A study at Baylor College of Medicine reveals the cellular composition of rare pediatric liver cancer and its response to treatment. Researchers found that these tumors contain three types of cancer cells and that they originate from hepatic stem cells.
Researchers at UCLA have developed a novel immunotherapy that uses CAR-NKT cell therapy to fight endometrial cancer. The therapy achieved complete tumor elimination and prolonged survival in mouse models, outperforming conventional CAR-T cell therapies.
New research from the University of Mississippi suggests that storytelling is just as effective, and sometimes better, than survival processing in improving memory. By creating a narrative with unrelated nouns, participants were able to remember more than those who used survival processing or pleasantness processing.
Researchers discovered diverse microbes on coral reefs, producing chemicals with promising applications in medicine and biotechnology. The findings highlight a critical dimension of conservation: the loss of coral reefs also loses a vast 'molecular library' linked to microbial life.
Researchers at Montana State University will study how avian flu viruses impact cells in the chicken intestine to better understand their growth, spread, and propagation. The study aims to find alternative strategies to vaccination, as current vaccines have unclear efficacy and can lead to food safety regulations and trade restrictions.
Impact Journals is exhibiting at the AACR Annual Meeting 2026 in San Diego, showcasing recent publications and discussing collaboration opportunities. The meeting highlights the latest advances in cancer science and medicine, with a focus on research impact, ethical standards, and scientific integrity.
Scientists have discovered that mosquitoes use a specific sensory receptor to detect and avoid borneol, an organic compound found in plant-based mosquito repellents. This finding has the potential to lead to the development of more effective and longer-lasting repellents.
A study found that people's responses to thoughts of mortality shape their travel decisions, with those in tourism hotspots seeking meaningful, slow experiences. In contrast, residents in low-tourism areas are more likely to adopt negative coping strategies, leading to fewer travel opportunities.
Researchers analyzed the teeth of four European straight-tusked elephants, discovering they migrated up to 300km before reaching their final habitat. The study suggests organized hunting and cooperation between Neanderthals and the elephants.
Researchers developed a water-rich, Jell-O-like hydrogel that mimics human tissue's movement, stretching, and relaxation. The hydrogel can be precisely controlled by light, enabling the study of cell behavior and disease modeling.
Researchers found that combining fermented and unfermented cocoa beans can balance flavor and nutritional value, increasing the market potential of Amazonian cocoa. The study also identified new molecules with antioxidant properties, suggesting Amazonian cocoa as a superfood
Astronomers have discovered a rare second-generation star, PicII-503, in the ultra-faint dwarf galaxy Pictor II, which preserves the chemical imprint of the first stars in the Universe. The star has an extreme overabundance of carbon and the lowest iron abundance ever measured outside of the Milky Way.
Researchers developed a targeted genetic therapy using milk-derived nanoparticles to attack cancer cells while sparing healthy tissue. The approach shows promise in treating aggressive bile duct cancer with limited treatment options.
Researchers from the University of Jyväskylä predicted that gold nanoclusters can selectively recognize chiral biomolecules, which could aid in detecting diseases directly from a blood sample. The study used computational simulations to examine nearly 300 cluster-biomolecule combinations and found clear differences in their interactions.
A new study by the University of Technology Sydney found that regular Group Clinical Supervision can meaningfully reduce burnout among midwives. The program provided a confidential setting for small groups to reflect on their experiences and develop strategies for managing emotional demands.
Researchers tracked 48 urban coyotes and found that over half of their dens were in natural structures, while others incorporated human-related items to create strong, hidden shelters. The study highlights the adaptability and intelligence of coyotes, which play a crucial role in urban ecosystems as apex predators and ecosystem engineers.
A Japanese-German research consortium is developing invisible magnets that can manipulate antiferromagnets ultrafast using intense light pulses. This approach has the potential to increase processing speed by a factor of 1,000, revolutionizing optical communication and information technology.
The research team developed a two-terminal-based AI semiconductor that precisely controls hydrogen with electrical signals, resolving speed degradation and high power consumption limitations. The device ran stably for over 10,000 repetitive operations and demonstrated learning and memory functions similar to human brain synapses.
The Dream Biology Award recognizes original ideas with potential to advance biological research and deliver benefits to society. The competition invites ambitious proposals across various biological sciences and offers a unique trophy and €10,000 prize.
A new US-based method using engineered yeast produces oxalic acid, enabling efficient and sustainable recovery of rare earth elements. The process extracts almost all the rare earth elements from low-grade ore with high efficiency.
The Brain & Behavior Research Foundation has awarded $1 million to 10 senior scientists conducting innovative research in neurobiological and behavioral science. The grants will support studies focused on critical mental health challenges such as depression, autism spectrum disorder, PTSD, and schizophrenia.
Research shows that babies can understand and engage in deception from as young as 10 months, with 1 in 4 by 17 months and 50% by 3 years old. Children's deception development builds in their first years, becoming more proficient and creative as they grow, and can involve various tactics like hiding, denial, and fabrication.
Scientists develop a simpler route-sensing signal to support accurate control in tendon-sheath mechanisms, opening doors to more compact and adaptable robotic systems. They found that friction-induced elongation is governed by the accumulated curve angle, enabling a comprehensive feedforward control framework.
A new technique harnessing Fourier ptychographic microscopy and coherence scanning interferometry provides accurate 3D morphology measurements of high-aspect-ratio micro-trenches. The method achieves high lateral resolution without iterative phase retrieval, enabling robust characterization of complex structures.
Researchers have developed a method to preserve brain tissue in a functional state using vitrification, allowing for long-term preservation and re-examination of neural networks. The technique enables the recovery of electrical signals and long-term potentiation, crucial for learning and memory processes.
Early alterations in the brain's clearance system may contribute to psychosis vulnerability. A study found that individuals with 22q11.2 deletion syndrome, a genetic condition, had impaired glymphatic system function from childhood, which may promote psychosis onset.
In a breakthrough study, researchers successfully integrated neuronal precursor cells into biobots, resulting in the formation of functional nervous systems. This development has significant implications for neuroscience, bioengineering, and regenerative medicine, enabling the investigation of fundamental questions about the origin of ...
Researchers discovered 30 bacterial species that break down biodegradable plastic, revealing speed and factors influencing degradation. The study highlights the importance of understanding microbial communities and plastic chemistry in plastic biodegradation.
A new study from the University of Vaasa investigates how adaptive machine learning and advanced sensor fusion methods can improve positioning accuracy, robustness, and efficiency. Device-based machine learning reduces dependence on cloud-based processing, strengthening privacy protection and contributing to discussions on trustworthy AI.
A new study from Drexel University found that individuals who spent more time in nature reported better dietary behaviors, such as eating more fruits and vegetables. Participants who spent more time in nature also experienced improved mental health, including reduced depression, anxiety, and stress.
Researchers from Institute of Science Tokyo reveal the SPP1–CD44–Hedgehog signaling pathway as a key driver of fibrosis in liver tumors, hinting at its potential as a therapeutic target. The study provides valuable insights into how liver tumors actively shape their surroundings, driving the onset and progression of fibrosis.
A recent study found that the 2008 recession significantly altered Americans' class identity, with most people perceiving themselves as a lower class after the event. The research used four longitudinal datasets and found that class identity decreased on average following the recession, even years after the market crash.
The latest English volumes in the Handbook of Construction Machinery series have been launched, featuring Chinese expertise in port, piling, concrete, and environmental sanitation machinery. The series, spanning 21 volumes and 20 million Chinese characters, provides a comprehensive overview of China's construction machinery sector.
Researchers developed dual-modulated vertically stacked transistors with nanoscale channels, overcoming current leakage issues. The device achieves stable operation and low power loss in 3D stacked structures.
Researchers discovered that PFK, a key sugar-processing enzyme, has a hidden function controlling cell division by unwinding RNA and promoting gene translation. The enzyme's ability to bind and unwind RNA was found to be crucial for cell cycle progression, with cells lacking PFK2 showing slowed growth and division issues.
A new brain pathway has been identified that enables humans to quickly detect and respond to 'scary' sounds, leading to increased self-reported fearfulness. This pathway is associated with better hearing ability in noisy environments.
Developed by CU Anschutz experts, the tool helps patients weigh treatment options and boosts confidence. The majority of patients reported it was helpful in their decision-making process, finding it useful and satisfied with the tool.
EDENT1FI has screened 100,000 children across Europe for early-stage type 1 diabetes, using standardized screening programs and harmonized data collection. The initiative aims to empower families to manage life with type 1 diabetes effectively and support children and adolescents with early-stage detection.
Researchers found that adults with ADHD exhibit more sleep-like brain activity, leading to more lapses in attention. This increased activity may be a key brain mechanism underlying attention problems in ADHD. Further study is needed to explore potential strategies to mitigate this activity.
Researchers analyzed Oregon Medicaid case data and found that severe burns requiring hospital-level care are a growing threat in the overdose epidemic. People who smoke drugs like fentanyl and methamphetamine account for most of these cases, with butane torches posing a significant risk due to locking mechanisms.
The cf-EpiTracing platform has been developed to detect and trace diseases from as little as 50 μl of human plasma, capturing detailed epigenetic fingerprints. It has delivered impressive results in early diagnosis and screening for colorectal cancer, achieving an accuracy rate of up to 97.6%.
Researchers developed a method to measure individual thresholds for change, finding that personal thresholds vary widely and that combining social network structure and individual thresholds improves real-world interventions. Strategies that target individuals connected to many others who are already adopting the change were most effec...
Researchers discovered that migration and invasion inhibitory protein (MIIP) suppresses colorectal cancer progression by preventing immune cells from adopting tumor-supportive behaviors. MIIP reduces cancer cell migration, invasion, and metastasis by interrupting an immune feedback loop involving STING, NFκB2, and IL-10.
A global analysis of over 2,300 seawater samples reveals human-made chemicals make up a significant portion of organic matter in coastal oceans. Industrial chemicals, including plastics and consumer products, dominate the anthropogenic chemical signal, persisting even 20 kilometers offshore.
Using azithromycin within one day triggers antibiotic resistance in the respiratory tract, according to a study published in Nature Microbiology. The researchers followed hospitalized COVID-19 patients and found that azithromycin changed the mix of microbes in the upper airway, leading to persistent changes for more than a week.
A new study describes an implantable brain-computer interface (iBCI) typing neuroprosthesis that can restore communication with speed and accuracy for people with paralysis. Two clinical trial participants, one with ALS and the other with a spinal cord injury, used the device to communicate rapidly and accurately, with a word error rat...
A new platform, Build Better Bones, offers evidence-based guidance and practical resources for osteoporosis management. The platform, developed by the International Osteoporosis Foundation, provides a trusted place for people with osteoporosis to start their journey, with a focus on exercise, nutrition, and home safety.
Researchers developed a computational tool that infers telomere length from structural changes in cells and tissues captured in medical biopsies. The TLPath model accurately predicts telomere length, providing new opportunities for studying human aging.
Continuing GLP-1/GIP agonists before upper endoscopy increased clinically significant residual gastric volume, but did not elevate adverse event risk. Clear liquids the day prior to the procedure may mitigate this risk.
Engineers at Harvard create microcombs on photonic chips, enabling compact, programmable frequency combs for precision measurement and telecommunications applications. The breakthrough makes electro-optic microcombs more practical, energy efficient, and diverse.
Researchers use NASA's James Webb Space Telescope to study the ultra-low-density planet Kepler-51d, which defies planetary formation models. A thick layer of haze on the planet obscures its chemical elements and origin, making it challenging to discern its formation process.
A systematic review of 42 studies reveals a rising trend in self-injury among children and youth in high-income countries, with significant variability across countries. The findings highlight the need for effective, contextually informed prevention strategies to curb this growing concern.
PrimeC, a combination of celecoxib and ciprofloxacin, targets neuroinflammation, iron accumulation, and abnormal microRNA activity in ALS. The PARADIGM study shows improved functional outcomes and reduced ALS-related complications with PrimeC treatment.
ToxIndex integrates AI agents to access and orchestrate toxicological resources, providing comprehensive risk assessments in hours. The platform addresses a critical need in chemical and drug safety, meeting the vision of the 2007 NRC report for 21st-century safety testing.
A cross-sectional analysis found significant delays in treatment initiation for early-onset colorectal cancer in all-urban populations, with young male, Asian or Pacific Islander, Black, or Hispanic patients disproportionately affected. These delays, exceeding 90 days, challenge assumptions of uniformly timely access in urban settings.
A clinical trial found that weekly injectable extended-release buprenorphine treatment resulted in higher rates of illicit opioid abstinence during pregnancy compared to sublingual buprenorphine. Serious adverse events were also less common in the extended-release group.
Researchers developed a comprehensive genetic risk calculator for metabolic disease by integrating genetic data from hundreds of thousands of people worldwide. The polygenic risk score outperformed existing disease-prediction models and predicted downstream morbidity and clinical interventions, particularly in non-European populations.
Febrile neutropenia is a chemotherapy complication that Traditional Chinese Medicine (TCM) can help alleviate. TCM combines tonifying qi and blood, warming yang, and strengthening the spleen and kidney to treat FN. Combining TCM with standard therapy significantly improves outcomes.
Dr. Sara Simblett brings expertise in digital health innovation, patient engagement, and technology integration to JMIR Neurotechnology. Her research focuses on improving access, quality, and outcomes of care through digital interventions.
Researchers discovered that acetylcholine can directly trigger the release of serotonin in the brain, promoting coordinated chemical signaling. This finding suggests that brain disorders may involve the internal coordination system being pushed into overdrive, leading to pathological increases in serotonin levels.
Researchers developed novel tantalate high-entropy ceramics coatings that surpassed 1500 °C thermal barrier performance. The coatings showed excellent structural integrity and stable fluorite crystal structure under rigorous thermal measurements.
A research team developed a machine learning accelerated design strategy to screen optimal BaTiO3-based high-entropy ceramic compositions, achieving ultrahigh energy storage performance and high efficiency. The designed ceramic exhibits excellent environmental stability and pulsed charge-discharge performance, paving the way for practi...
SwRI is using low frequency eddy current testing to detect and characterize subsurface flaws and cracks in bolt holes. This method will allow aircraft maintainers to assess damage progression and make repair decisions to keep the aircraft flying safely.
Researchers found that reforestation in tropical regions, such as the Amazon basin and West and South-East Africa, can have a significant cooling effect due to high evapotranspiration rates. This approach can be more efficient than previously thought, especially when combined with other climate protection strategies.
Researchers developed lead-free relaxor ferroelectric ceramics with enhanced energy storage and ultrafast discharge capabilities. The high-entropy approach and bandgap engineering enabled grain refinement, increased resistivity, and a broader bandgap, contributing to a significantly enhanced breakdown electric field.
Researchers tested ChatGPT with over 700 hypotheses, finding the AI was accurate 76.5% of the time, but struggled to identify false statements and was inconsistent in its answers. The study highlights the need for skepticism and caution when using AI for critical tasks, particularly those involving nuance or complex reasoning.
A recent study on sheep genome sheds light on regulatory elements that influence gene expression, providing tools for breeders to select beneficial traits and avoid disease. The study mapped gene promoters and enhancers in various tissues, offering a platform for exploring future research across multiple animal species.
A concerning rise in adolescent obesity has been found, with overall rates climbing to 15.9% in 2023. Obesity patterns also reveal a decline in weight-loss attempts, with females more likely to attempt weight loss but fewer adolescents reporting efforts in 2023.
Researchers found that nearly 80% of patients with elevated Lp(a) >50 mg/dL did not initiate lipid-lowering therapy, highlighting selective responses to elevated Lp(a). PCSK9 inhibitors and aspirin initiation were also less common among patients with elevated Lp(a).
The new framework groups stations with similar hydrological behavior, reducing computational cost while maintaining high predictive accuracy. This approach enables scalable, data-efficient AI systems for water level forecasting, supporting flood early-warning systems, optimized reservoir and irrigation management, and improved decision...
Climate mitigation policies may increase hunger risk due to land use competition, but ozone reduction benefits partially offset these effects. Ozone-driven yield gains reduce food prices and increase food availability, particularly in regions with severe hunger.
A new clinical trial will investigate whether adding the oral medication vorasidenib to standard chemotherapy improves progression-free survival for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma. The study aims to recruit 400 individuals with this type of brain cancer and evaluate the safety and side-effect profile of the...
A new class of molten planet has been discovered, with a permanent ocean of magma and a unique composition of heavy sulphur molecules. This exoplanet, L 98-59 d, is unlike any known planet in our Solar System and may be the first of its kind in the galaxy.
Researchers at the University of Edinburgh have developed a method to transform post-consumer plastic into L-DOPA, a frontline medication for Parkinson's disease. The process harnesses the power of bacteria to break down PET waste and produce L-DOPA, providing a sustainable solution to the production of pharmaceuticals.
A new trial found that infants and toddlers with unilateral cerebral palsy show significant improvements in hand and arm function when receiving early, high-dose therapy. The study suggests that multiple approaches can help children build critical motor skills, providing families and clinicians with evidence-based options.
Researchers have uncovered unusual clustering of endothelial cells around immune cells, signaling the start of excessive collagen production and scarring. This discovery could lead to new treatments for fibrosis, a common complication in Crohn's Disease affecting 10-20% of patients.
A national poll finds 1 in 3 parents worry their teen or young adult driver could cause an accident, with most witnessing unsafe driving behaviors. Despite concerns, most parents rate their child's driving as average or better, and relatively few impose consequences for risky behaviors.
A novel drug delivery system developed by Osaka Metropolitan University improves Paclitaxel absorption by binding to the lipocalin-type prostaglandin D synthase enzyme, enabling selective delivery to cancer tissues. The system demonstrates significant tumor suppression effects even after administration cessation.
The new guidelines, based on 137 systematic reviews, emphasize the importance of consistency and effort in resistance training. The primary goal for most adults should be to build a consistent routine, which can be achieved with elastic bands, bodyweight training, or home-based routines.
A large study found that Asian mothers experience a 1.5-fold higher rate of obstetric trauma, while Black immigrant and refugee mothers have a 20-30% higher risk. The study also found that immigrants with shorter duration of residence had higher initial risk of obstetric trauma, which declined with increasing time in Canada.
A study extending pregnancy monitoring from conception to 6 weeks postpartum found nearly 10,000 cases of severe maternal complications in Canada each year. This reveals significant cases were previously missed, emphasizing the importance of postpartum care and timely interventions.
A new framework, DUPGT-CDR, uses gating networks to effectively incorporate both positive and negative feedback in cross-domain recommendation systems, achieving lower prediction errors and improved convergence speed. The framework offers more precise product recommendations and personalized learning resources across various domains.