Thousands of Medicare beneficiaries developed postoperative infections up to six months after coronary artery bypass grafting or aortic valve replacement. Women had a 60% greater odds of developing infections, including urinary tract, pneumonia, and sepsis.
A study published in The Journal of Immunology found that supplementing maternal diet with vitamin E during pregnancy can reduce the development of food allergy and anaphylaxis in newborn mice. This potential breakthrough could help address the alarming increase in peanut allergy among children.
A study published in Mayo Clinic Proceedings found that patients who can exercise during cardiac stress testing have a lower mortality rate than those who cannot. The researchers discovered that assessing a patient's ability to exercise during testing provides a stronger distinction between high- and low-risk patients.
Researchers have developed two therapeutic cocktails that inhibit key molecules, stopping immune cells from overreacting to allergens. The treatments reduced asthma attacks in mice by erasing the immune system's memory of asthma-causing allergens.
Plastic Back and a US-based recycler partner to scale low-temperature chemical recycling technology converting hard-to-recycle plastics into valuable byproducts. The partnership aims to address the global plastic waste crisis, reducing landfill waste and dependency on virgin raw materials.
A new device has been designed to effectively treat cerebral venous sinus thrombosis (CVST) by navigating complex venous anatomy and removing large thrombi. The device features controllable axial and longitudinal maneuverability, improving clinical outcomes for patients with CVST.
A Canadian study of over 2,500 adolescents and young adults found that supplement users are more likely to experience muscle dysmorphia. The study suggests a potential link between muscle-building supplement use and the development of this condition.
An international team of researchers has created a detailed map of individual cells in the adult lung, including those affected by chronic lung disease. The AI-driven finding shows that some lung tissue in patients with idiopathic pulmonary fibrosis (IPF) exhibits signs of the disease before significant structural changes occur.
A study published in the journal Memory found that intoxicated people have difficulty accurately recalling internal facial features, while still remembering external details like hair style. This suggests that alcohol narrows attention to more noticeable external features, impairing memory for critical internal features.
UT Health San Antonio has earned the prestigious Research 1 designation from the American Council on Education and the Carnegie Foundation for its exceptional research expenditures and number of doctoral degrees awarded. The institution has made significant strides in biomedical discovery, medical education, and economic growth.
A synthetic retinoic acid-inducible gene I (RIG-I) agonist RNA has been shown to induce innate immune signaling and death of hepatocellular carcinoma cells in vitro. The addition of recombinant interferon-b potentiated this cell death, suggesting a potential new mechanism for treating patients with liver cancer.
Researchers develop dual-stage E+S-band bismuth-doped fiber amplifier for next-generation optical communication systems. The device achieves unprecedented broad bandwidth, high gain and low noise, making it suitable for boosting optical signals.
Researchers developed innovative RE³⁺-doped monolithic glasses capable of tunable full-color emission under NIR laser excitation. These glasses overcome key obstacles faced by existing technologies and demonstrate the potential as materials for dynamic, full-color laser-based volumetric displays.
A study found that emergency clinician prescribing of buprenorphine increased in California, leading to more patients starting treatment for opioid use disorder. The efforts were successful in getting patients started, with at least one in three filling a second prescription within 40 days.
Ketamine has been shown to rapidly reduce depressive symptoms in patients with treatment-resistant depression, often within hours of administration. However, the long-term efficacy and safety of ketamine therapy remain uncertain, with potential risks including cognitive impairment and cardiovascular effects.
Research advances higher-order networks to capture multi-agent interactions, enabling accurate modeling of biological, social, and physical systems. The Dirac-Bianconi operator provides a powerful generalization of the graph Laplacian, encoding local and global interactions across different topological dimensions.
Researchers have discovered double negative memory B cells, a novel subset of immune cells that are more dysfunctional when in close contact with tumors. These cells may be a useful diagnostic marker and a potential target for developing new immunotherapies.
Researchers at UCSF have identified unique, cancer-specific proteins created through mistakes in RNA splicing. These antigens could be used to create potent immunotherapies that recognize and attack hard-to-treat tumors. The discovery offers new hope for glioma patients and expands the number of targets available for cancer therapy.
Researchers discovered a genetic mutation that increases glycine decarboxylase enzyme, linked to schizophrenia behaviors in mice. The study provides a direct genetic link to psychosis and sheds light on the biochemical pathways involved.
Three early-career scientists, Dr. Omar Abudayyeh, Dr. Caleb Lareau, and Dr. Yuzhong Liu, are awarded $150,000 grants for their innovative research on human immunology, vaccine discovery, and cancer immunotherapy. Their proposals aim to advance our understanding of the immune system and develop new treatments for deadly diseases.
A study by NYU Abu Dhabi researchers found that children from the Fulani group have a distinct immune response to malaria, with key differences in immune cell activity offering greater protection. The study highlights the impact of genetics and lifestyle on immune responses.
Stanford researchers have developed a practical and low-cost method to remove atmospheric carbon dioxide from the air using common minerals. The new process, known as enhanced weathering, uses heat to transform silicates into materials that capture and store CO2, offering a potentially scalable solution to mitigate global warming.
Fossil discovery in Australia rewrote the evolutionary history of theropod dinosaurs, revealing a predator hierarchy unique to Cretaceous Australia. The findings showcase the world's oldest known megaraptorid fossils and the first evidence of carcharodontosaurs in Australia.
A pilot study shows that a text messaging system can safely reduce the amount of time some patients spend receiving cancer treatment. The platform, which was tested in a clinical trial, allowed patients to complete symptom checks and receive approval for fast-tracking their treatments, saving them over an hour per visit.
Cancer cells work together to source nutrients from their environment, a cooperative process that can be targeted for treating cancer. Researchers identified key enzymes and mechanisms behind this cooperation, including the enzyme CNDP2, which can be inhibited by the drug bestatin.
Researchers at Newcastle University have developed a new environmentally-friendly mortar made from recycled plastic and silica aerogel, which improves insulation and reduces plastic waste. The new mortar mix reduced heat loss by up to 55% while maintaining the required strength for masonry construction.
A representative study of adults experiencing homelessness in California found a high proportion of current drug use and unmet need for treatment. Improving access to treatment tailored to their needs could improve outcomes.
Professor Kazunari Domen's research develops novel materials and techniques for efficient solar energy harvesting and scalable hydrogen production. His work enables the successful development of large-scale solar-driven hydrogen production units, paving the way for a clean energy future.
Advances in orbit determination using GNSS observations and inter-satellite ranging enhance accuracy and computational efficiency for large LEO constellations. The research introduces stepwise autonomous methods reducing computational burden while improving precision.
A new study finds that US hospital staffed beds have decreased by 16%, leading to a potential national bed shortage. The US could reach an 85% occupancy rate as early as 2032, with some states at higher risk than others.
A consortium of researchers and hospitals in Madrid has created a children's exoskeleton for domestic use, enabling children with gait impairments to walk at home or outdoors. The prototype features four motors that mimic natural muscle function and adapts to the child's growth.
A large-scale study examined the relationship between nutrients and sleep using data from people who used mobile applications to track their eating and sleeping habits. The results showed that participants with high protein, monounsaturated fatty acid, and polyunsaturated fatty acid intake had improved sleep outcomes.
The Dark Energy Spectroscopic Instrument (DESI) has discovered a treasure trove of actively feeding black holes in small galaxies, revealing surprisingly few are of intermediate mass. The team identified 300 new intermediate-mass black hole candidates and 2500 active black holes in dwarf galaxies.
A new classification system for SJS/TEN divides the disorder into five types based on causative factors and diagnostic algorithms. This typology aims to bring clarity to diagnosis and treatment by providing consistent criteria for identifying underlying causes.
Physicists from ISTA reveal that the contact history of materials determines how they exchange charge, explaining the unpredictability of contact electrification. By analyzing identical materials, they discovered a triboelectric series and found that repeated contact allows samples to evolve and order correctly.
A new study identifies two groups of brain cells that help the mouse brain gauge the full range of possible rewards associated with a choice. The researchers used machine-learning concepts to study brain circuitry supporting reward-based decisions in mice, shedding light on how the human brain makes such choices.
A three-year effort in nine California counties resulted in 227 individuals receiving new sentences, with 174 offenders released by September 2024. Researchers recommend increasing funding, training for prosecutors and public defenders, and standardization of review factors to strengthen the program.
A study by researchers from Florida Atlantic University and Hanyang University explores how AI service quality affects retail employees' innovation, job fit, and job satisfaction. The results suggest that employees are more likely to engage in innovative behaviors when they perceive benefits from AI interactions.
Researchers at the Technical University of Denmark have found that adding biochar to chicken feed can significantly reduce campylobacter levels in free-range chickens. The study, published in Poultry Science, demonstrates an 80% reduction in campylobacter and suggests a potential tool for improving public health.
Researchers found that combining ultraviolet light with chlorine significantly enhances toxin degradation in water without generating harmful byproducts. The study suggests using UV/chlorine as a final barrier against toxins from algal blooms, minimizing unintended toxic consequences.
Researchers develop a new electronic fine-tuning approach to enhance the interactions between zinc and ruthenium, resulting in a highly active and stable catalyst for both oxygen reduction reaction and hydrogen evolution reaction. This breakthrough offers a cost-effective alternative to conventional platinum-based catalysts.
A new study found that artificial sweetener aspartame triggers insulin spikes leading to blood vessel inflammation in mice, which can contribute to atherosclerosis and increased risk of heart attacks and stroke. The researchers identified an immune signal called CX3CL1 that plays a key role in this process.
Global glacier mass loss has increased by 36% since 2000, with 6,542 billion tons lost between 2000 and 2023. This results in an 18 mm annual contribution to global sea-level rise, making glaciers the second-largest contributor after ocean warming.
Researchers develop a novel adaptive nonlinear PID controller integrated with radial basis function neural network for enhanced ballbot functionality. The proposed NPID-RBFNN controller demonstrates superior stability and robustness, outperforming traditional PID and NPID controllers.
A team of researchers found that mountain ranges with deep mantle rocks near the surface are ideal for large-scale natural hydrogen generation and accumulation. This process, called serpentinization, can produce up to 20 times more hydrogen than in rift environments, providing a promising alternative to synthetic hydrogen production.
Nanomaterials conjugated with drugs improve therapeutic efficacy, reduce toxicity, and enable targeted delivery for neglected tropical diseases. This approach enhances diagnosis with rapid, sensitive, and cost-effective biosensors.
Researchers discovered that Arctic glaciers are leaking significant amounts of methane through the 'glacial fracking' process. This previously unrecognised process could contribute to Arctic climate feedbacks and accelerate global warming.
Research reveals oxygen vacancies in ZrO2 catalysts increase catalytic performance in propane dehydrogenation. The vacancies create a localized electronic state that promotes the activation of C-H bonds in propane.
A new plant species, Nasa katjae, has been discovered in Peru's Andean cloud forests through citizen science efforts. The species is characterized by its scarlet-red flowers and is potentially vulnerable due to habitat loss and climate change. The discovery emphasizes the importance of protecting remaining pristine habitats.
A new study found that generic drugs made in India have significantly more 'severe adverse events' for patients, including hospitalization and death. The researchers matched 2,443 drugs made in the US and emerging economies, finding that mature generic drugs were responsible for the higher rates of severe adverse events.
BGI Genomics' Indonesian joint venture signed a partnership agreement to advance prenatal genetic screening technology in Indonesia. The collaboration focuses on extended Non-Invasive Prenatal Test (NIPT-Pro) and Copy Number Variation Sequencing (CNVseq) for early detection of fetal genetic disorders.
APTE 2025 aims to address transportation challenges through innovative solutions while promoting inclusivity, reliability, and sustainability. Researchers are invited to submit papers on emerging transportation solutions for building efficient, sustainable, reliable, and inclusive transport systems.
A new leaf vein-inspired design combines rapid movement with impressive load-carrying capacity, overcoming previous actuator limitations. The research opens up new ways for designing faster, stronger and more versatile actuators with wide-ranging applications.
Researchers at Sainsbury Wellcome Centre develop novel experimental setup called Translocator, isolating fundamental elements of locomotion and motion-source separation. The team finds that individual cells in primary visual cortex use motor and vestibular signals to determine visual flow origin.
A new method combines traditional histopathology with spatial transcriptomics data to improve understanding of chronic kidney disease lesions at the cellular and molecular levels. This approach has the potential to identify new biomarkers and therapeutic strategies for patients.
Recent advances in AI methodologies are performing well with limited data, opening new areas for health improvement across countries. AI has the potential to transform pandemic preparedness by predicting outbreaks and their impact on individual patients.
Tampere University has licensed a drug molecule intended for treating Epidermolysis Bullosa, a group of rare and severe skin disorders. The licensing agreement includes collaboration with Theravia to develop, register and commercialise the drug.
Researchers discovered a common cognitive feedback loop used by Buddhist jhāna meditation and Christian speaking in tongues practices to achieve profound focus and joy. This 'Attention, Arousal and Release Spiral' offers insights into cultivating deep states of tranquility and bliss.
A study from Waseda University found that Japan's Stewardship Code amendment encouraged institutional investors to disclose their voting records, leading to increased shareholder dissent in director elections. Domestic investors were more likely to react than foreign investors, with dissent strongest against underperforming directors.
Researchers developed a compact swimming robot that can maneuver through tight spaces and transport heavier payloads. The robot uses silently undulating fins to propel itself and achieves impressive speeds of 12 centimeters per second.