Researchers have developed a new pipeline using artificial intelligence to predict which proteins natural toxins will affect, with implications for ecological research and drug development. The method uses AI models to analyze water molecule movement around potassium channels, identifying specific targets of the cone snail toxin.
Researchers have developed a new computational modeling approach to capture the complex shapes that viral proteins can adopt. By applying this approach to a key protein involved in COVID-19 replication, scientists have created a detailed picture of its dynamic behavior.
Marcel P. Goldschen-Ohm wins the 2024 Paper of the Year-Early Career Investigator Award for his study on GABA receptor subunit linkers and their role in pore gating and diazepam modulation, challenging conventional views on receptor function.
A new tool measures how individual phytoplankton cells are using energy, revealing unique ways each species adjusts to light changes. This helps predict and observe ocean responses to climate change and assess phytoplankton health.
Scientists discovered sweet taste receptors on the surface of heart muscle cells, which increase the force of contraction when stimulated with artificial sweeteners. This breakthrough may lead to novel treatments for heart failure and provide insight into arrhythmogenesis.
A new study reveals a specific genetic mutation in the Apennine brown bear population that impairs cellular energy production and increases harmful byproducts. This mutation is linked to reduced overall health and survival in these critically endangered bears.
A new approach enables researchers to generate antibodies against transitory protein targets, providing insights into disease mechanisms and potential therapeutic targets for Alzheimer's and Parkinson's.
Research reveals key differences in immune system response to Alzheimer's and bacterial infections, with larger Aeta clumps triggering more chronic inflammation.
A team from Tokyo Metropolitan University has successfully implanted myoblasts onto healthy muscle in mice using an extracellular matrix scaffold. This breakthrough treatment could treat ageing-related muscular atrophy without scarring, offering a promising avenue for regenerative medicine.