Biologists have identified a new type of regulation that influences the expression of about half of all human genes by targeting specific introns. This discovery adds complexity to the process of gene expression and suggests potential therapeutic targets for diseases such as blood cancers and spinal muscular atrophy.
Heavy screen use, particularly social media and video games, is associated with an increased risk of developing manic symptoms in U.S. preteens. The study found that prolonged screen time can lead to behaviors characteristic of bipolar-spectrum disorders, including inflated self-esteem, decreased sleep needs, and impulsivity.
Researchers have made a significant leap forward in Brillouin microscopy, providing a 1,000-fold improvement in speed and throughput. The new technology enables full-field imaging with minimal light intensity, opening up new possibilities for life scientists.
Deep Nanometry enables high-speed analysis of nanoparticles, detecting even trace amounts of rare particles like extracellular vesicles indicative of colon cancer. This technique has potential applications in various fields including vaccine development and environmental monitoring.
Developed by Doshisha University researchers, vmTracking assigns virtual markers to track multiple animals without physical markers. It outperforms traditional methods in crowded environments and demonstrates high accuracy in tracking various species, including fish schools and human dancers.
Researchers developed a liquid fertilizer replacing unsustainable chemical fertilizers with organic waste, producing up to 100% of nitrogen and 77% of phosphorus. The method also increases phosphorus solubility by adjusting pH levels.
Researchers at Doshisha University reveal that 25-hydroxycholesterol causes a specific type of cell death called ferroptosis, which could contribute to various diseases. The study identifies two key mechanisms by which 25-OHC induces ferroptosis, including inhibition of cellular pathways and disruption of antioxidant systems.
Researchers have discovered a novel gene therapy that can reverse conduction slowing and prevent cardiac arrhythmias by introducing the SCN10a-short gene into heart muscle cells. The treatment has shown promise in animal models and human cell studies, offering a potential solution for millions affected by arrhythmias worldwide.
Researchers found that fog water can be harvested in the Atacama Desert to ease water scarcity affecting vulnerable populations. The collected water can be used for drinking, irrigation, and local food production, with potential yields of up to 300,000 liters per week.
Chronic exercise training affects female athletes' energy expenditure and slow-wave sleep patterns differently than general women, influenced by menstrual cycles and reproductive functions.
A new study finds that non-intervention deadwood stands support the most diverse beetle communities, while salvage logging reduces diversity. Mixed management approaches combining deadwood with diverse vegetation can enhance landscape heterogeneity and connectivity.
A new type of phosphor-in-glass film converter on heat-conducting substrates has been developed to improve the performance and efficiency of high-brightness laser lighting. The researchers found that the converters with different substrates have varying effects on heat transfer, light transport, and luminescence saturation.
Researchers from the University of Oxford challenge the long-held assumption that water temperature determines the efficiency of ocean carbon capture. The study highlights the need for standardized data collection methods and improved monitoring in polar regions to better understand this critical process.
A groundbreaking study published in eBioMedicine has shown that a new mRNA vaccine is effective in boosting immunity against tuberculosis. The vaccine demonstrated potent immune responses in infected mice and improved long-term protection when combined with the BCG vaccine.
A new field study on CHS suggests that this approach could revolutionize forest stand volume estimation, providing consistent results across varying environmental conditions. The method eliminates potential biases from traditional methods and offers efficiency advantages in terms of measurement time.
Researchers have identified a new variant, clade 1b, of the mpox virus that has become more infectious and is spreading rapidly across borders. The study found that this variant primarily spreads through heterosexual contact in densely populated areas, with an estimated fatality rate of 3.4%.
The study found that global age-standardized mortality rate for suicide declined by nearly 40% from 1990 to 2021, but progress is not universal, with four regions reporting increases in suicide rates. Males were more than twice as likely to die by suicide than females, but females were 49% more likely to attempt it.
Macrophages expressing high Spp1 levels are found in emphysema patients and those exposed to cigarette smoke or soot-like particles. This study highlights Spp1 as a crucial mediator of environmental particle pollution-related COPD development, offering potential preventive targets.
The Childhood Obesity Prevention, Evaluation and Treatment Toolkit provides healthcare providers with practical guidance for preventing, evaluating, and treating childhood obesity. The toolkit is grounded in scientific evidence and offers actionable treatment approaches for children and adolescents dealing with overweight and obesity.
The National Natural Science Foundation of China funded 76 projects to study air pollution complex, achieving significant advances. Research focuses on instrument development, modeling studies, and understanding the impact of heterogeneous processes on haze chemistry.
The joint venture will unite the nation's largest comprehensive pediatric system with a top pediatric cancer program and the nation's leading comprehensive cancer center. The collaboration aims to accelerate improved outcomes for patients in Texas and around the world, increasing access to clinical trials and innovative treatments.
A public consultation in the UK found that 90% of respondents would agree to genetic testing for personalized medication use. The study aims to better understand the public's views on pharmacogenetics and its potential impact on healthcare.
Despite increased efforts to address racism, underreporting remains a significant issue, particularly on clinical placements. Initiatives are transforming workforce experience and representation, but true equity will take time to achieve.
A systematic review of 38 studies found that frequent use of health and fitness apps is associated with problematic habits related to food and exercise. The research highlights the need for app developers to consider the psychological impacts of these tools on users' mental health.
A panel of international experts recommends against spine injections for adults with chronic back pain, as they provide minimal pain relief. The advice is based on the latest evidence and aims to reduce the burden of these costly and potentially harmful procedures on patients.
SLAC is part of a collaborative team led by General Atomics to develop fusion fuel targets and overcome critical technological challenges. The lab will receive $1 million per year to develop advanced target tracking technology, helping bridge basic research with the growing fusion industry.
Groundbreaking research from the CLEAR study reveals that greater tumor shrinkage improves survival outcomes for patients with advanced renal cell carcinoma. The lenvatinib and pembrolizumab combination regimen demonstrates significant long-term benefits, including enhanced effectiveness of subsequent treatments.
A report by University of Cambridge experts highlights the risks of unregulated AI use on UK's thriving creative sector. The researchers argue that forcing creatives to 'opt out' of AI training could compromise their livelihoods, particularly those just starting out.
The joint venture aims to build the world's preeminent pediatric cancer center, increasing access to care and clinical trials. Collaborative operations will launch in early 2026, featuring a focus on new facilities with latest medical technology.
Scientists have pinpointed two proteins in immune cells that, when blocked, can significantly reduce lung tissue scarring and restore regeneration. Blocking YAP and TAZ can curb scar formation by dampening inflammation, maintaining a healthy immune cell ratio, and disrupting their communication with nearby cells.
A global study by Amsterdam UMC found that new medication direct oral anticoagulants (DOACs) are equally safe and effective as vitamin K antagonists (VKAs) for treating sinus thrombosis. Regular monitoring is no longer necessary, making it more user-friendly.
Researchers have confirmed that aggregates called 'marine snow particles' can support nitrogen (N2) fixation by bacteria worldwide. The study reveals that this process accounts for about 10% of total N2 fixation in the global ocean, with bacterial activity distributed latitudinally across different temperature ranges.
Researchers at University of Hawaii at Manoa have discovered 10 new marine sponge species in Kāneʻohe Bay, expanding our understanding of sponge biodiversity in the Hawaiian archipelago. The discovery sheds light on the crucial role sponges play in regulating and sustaining coral reef ecosystems.
A new study in mice found that young adults are more susceptible to nicotine addiction than middle-aged adults, with a greater acute response to nicotine. The effects of nicotine on the body change over the lifespan, affecting how medications and other chemicals are processed.
The Grubhub Community Fund has awarded the American Heart Association a $2 million grant to support food security, technology innovation, and economic resiliency in New York City and Chicago. The funds will be allocated to up to 12 organizations and entrepreneurs focused on improving health equity and expanding access to capital.
A pioneering study demonstrates the feasibility of treating SMA prenatally using risdiplam, a drug administered to an expectant mother during pregnancy. No identifiable features of SMA have been observed in a 2.5-year-old child, suggesting a promising outcome for future research.
The FDA has approved vimseltinib, a targeted therapy, for treating symptomatic tenosynovial giant cell tumor (TGCT). Vimseltinib demonstrated significant reduction in tumor volume and improvement in quality of life for patients, with fewer side effects compared to pexidartinib.
The number of US work stoppages decreased by 23.8% in 2024 compared to the previous year, with a notable drop in one-day strikes. The approximate number of workers involved in stoppages also declined by 45.5%.
A new experimental concept called ultrafast vortex electron diffraction allows for direct visualization of electron movement in molecules. This technique effectively isolates coherent electron dynamics, enabling deeper insights into energy transfer and material behavior.
Global glacier melt accelerated over the last decade, with a 36% increase in meltwater compared to the previous decade. This poses significant risks to drinking water supplies, particularly in South America and Asia due to rising sea levels and increased flooding after the melt season.
Assistant Professor Tova Holmes at University of Tennessee Knoxville received a $75,000 Sloan Research Fellowship for her work on searching for new fundamental particles using colliders in high-energy particle physics research.
The Columbia Climate School has launched a one-year master's degree program in Climate Finance, combining courses in climate science, adaptation, mitigation strategies, international climate finance, capital markets, and more. The program aims to equip students with financial decision-making skills needed to respond to the climate crisis.
The University of Texas MD Anderson Cancer Center received nearly $23 million in CPRIT funding to advance cancer research, translational science, and clinical trials. The funding will support the recruitment of a first-time tenure-track faculty member and enhance the understanding of cancer biology.
A new study by Connecticut College reveals that palm trees once thrived in subarctic Canada during the late early Eocene, approximately 48 million years ago. This finding indicates a warmer climate with ice-free winters, unlike previous assumptions.
UTA research projects contributed $59 million to the national economy in 2024, supporting student development and collaboration with other research organizations. The university's research infrastructure, including cutting-edge equipment, helped drive economic impact in North Texas and beyond.
A new study suggests that a menthol cigarette ban could be less effective due to the emergence of an illegal market. The research found that demand for menthol cigarettes would remain high even with limited access to e-cigarettes, leading to a significant black market. This could blunt the intended public health benefits of the ban.
A study published by the American Academy of Neurology found that smoking is a key factor in unexplained strokes among younger adults. Researchers discovered that heavy smokers had nearly four times the risk of stroke compared to non-smokers, with the highest risk seen in male participants and those aged 45-49.
Researchers at WashU created a new model that uncovers brain mechanisms behind focusing amid distractions, finding people ignore past distractions but stay open to other inputs. The model demonstrates attention control by modulating focus on distractors and target tasks.
Kimberly Stegmaier appointed as Chair of Pediatric Oncology at Dana-Farber Cancer Institute and Associate Chief of Division of Hematology/Oncology at Boston Children's Hospital. She will focus on acute leukemias and pediatric solid tumors, pioneering genomic approaches to identify new therapies for childhood cancer.
A new study reveals US hospital occupancy has surpassed pre-pandemic levels, driven mainly by a 16% reduction in staffed hospital beds. This could lead to a bed shortage as early as 2032, posing significant risks to patient safety and mortality rates.
Researchers found that large language models use a semantic hub mechanism to process diverse data, integrating information from various modalities. They demonstrated that models can change their outputs by intervening with text in the dominant language, even when processing other languages.
Researchers at Yale University have created a new method for converting industrial carbon dioxide into a renewable fuel, namely methanol. The breakthrough involves a two-step chemical reaction and demonstrates the potential for large-scale industrial applications.
Researchers have used CRISPR gene editing to study the regulation of the Unusual Floral Organs (UFO) gene in plants, uncovering the importance of conserved non-coding DNA sequences in controlling flower formation.
A new study of over 1400 adults found loot box buying associated with real-world gambling, video gaming addiction, and mental health issues. Researchers highlight the need for regulations to address this growing concern.
A new study reveals that asymptomatic neonatal HSV infections in mice can lead to persistent CNS infection and long-term cognitive decline. Maternal vaccination may prevent this cognitive impairment, suggesting a potential strategy for reducing neurological damage in infected offspring.
Researchers at Incheon National University have pioneered a novel resonant tuning rectifier (RTR) for parallel compensated receivers in wireless power transfer. The RTR enhances efficiency via dynamic frequency adaptation, reducing circuit impedance and minimizing interference with other devices.
A new study reveals that dust storms are associated with a heightened risk of asthma, culture-negative pneumonia, and other health conditions. The research found an increase in emergency department visits for these conditions in three Southwestern U.S. states between 2005 and 2018.
A long-term study found that Roux-en-Y gastric bypass outperforms sleeve gastrectomy in treating obesity, with patients losing more excess body mass index. The Swiss Multicenter Bypass or Sleeve Study demonstrated the superiority of Roux-en-Y gastric bypass over sleeve gastrectomy for patient weight loss.
A new laser-based device can analyze gas samples with high precision, detecting molecules at minute concentrations. The technology has potential applications in medical diagnostics, tracking greenhouse gas emissions, and more.
Record-breaking temperatures and devastating floods ravaged Southern Appalachia in 2024, claiming lives and destroying homes. The region faced unpredictable conditions, including scorching heat and heartbreaking losses from flooding.