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Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging

02.16.25 | Higher Education Press

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The principle of SIFA and LipoFRET
AThe fluorescence of a fluorophore changes rapidly with its distance to a graphene oxide layer.BThe experimental setup of SIFA on TIRF microscopy.CThe morphology (upper panel) and the profile of the thickness (lower panel) of a lipid bilayer composed of DOPC/DOPA.DThe dependence of the relative intensity on distance in SIFA with different critical distancesd0 (Liet al.2016).EThe scheme of LipoFRET.FFRET from one donor to multiple acceptors.GThe absorption spectra of TB (blue) and the emission sp Credit: Chenguang Yang, Dongfei Ma, Shuxin Hu, Ming Li, Ying Lu

Key Findings :

Significance : The development of SIFA and LipoFRET represents a significant advancement in the field of membrane protein research. These techniques offer valuable tools for understanding the structure and function of membrane proteins, and their potential applications in drug discovery and disease treatment.

The work entitled “ Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging ” was published on Biophysics Reports (published on December, 2024).

Biophysics Reports

10.52601/bpr.2024.240024

Experimental study

Cells

Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging

31-Dec-2024

Keywords

Biophysics

Article Information

Journal
Biophysics Reports
DOI
10.52601/bpr.2024.240024
Method of Research
Experimental study
Subject of Research
Cells
Article Publication Date
2024-12-31
Article Title
Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging

Contact Information

Rong Xie
Higher Education Press
xierong@hep.com.cn

Source

Original Source
https://journal.hep.com.cn/br/EN/10.52601/bpr.2024.240024

How to Cite This Article

APA:
Higher Education Press. (2025, February 16). Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging. Brightsurf News. https://www.brightsurf.com/news/1WR9YD9L/real-time-analysis-of-nanoscale-dynamics-in-membrane-protein-insertion-via-single-molecule-imaging.html
MLA:
"Real-time analysis of nanoscale dynamics in membrane protein insertion via single-molecule imaging." Brightsurf News, Feb. 16 2025, https://www.brightsurf.com/news/1WR9YD9L/real-time-analysis-of-nanoscale-dynamics-in-membrane-protein-insertion-via-single-molecule-imaging.html.