Researchers from NUS and Los Alamos National Laboratory have discovered that Samarium-based nickelates can regain superconducting ability under strong magnetic fields. This reentrant superconductivity persists beyond 60 tesla, a significant breakthrough for practical superconducting technologies.
The ST-NUS HELIX Corporate Lab aims to develop new generative and embodied AI use cases at the edge through system-to-silicon innovation, reducing energy consumption and improving performance. Researchers will focus on memory-centric architecture, innovative in-memory computing, and scalable compute-and-memory systems.
Researchers from NUS have developed a method to turn waste from aircraft composite materials into aerogels that can be used for thermal insulation, sound absorption, and oil spill clean-up. The aerogels were found to be lightweight, non-toxic, and effective in absorbing sound and oil.
Researchers from NUS uncover a mechanism that helps cancer cells hide from the immune system by suppressing natural danger signals. Targeting this 'hidden switch', DDX6, could make tumours more visible to the immune system, improving existing or new immunotherapies.
Researchers at NUS engineered baker's yeast to sense and respond to red and blue light, enabling dynamic control over cellular behavior. The breakthrough uses optogenetics to deliver complex instructions without repeated chemical inducers.
NIRBA Hub fosters interdisciplinary collaboration & accelerates innovation in RNA science. The hub supports talent development, technology innovation & industry engagement.
Researchers at NUS have developed a new method called qChIP-MS to identify groups of proteins that work together at specific locations on DNA. This technique allows scientists to better understand how DNA is organised and regulated inside our cells, which could lead to breakthroughs in cancer biology and genome regulation.
Researchers have developed novel spintronics-based probabilistic processors that accelerate complex optimisation tasks while consuming less energy. The systems achieved significant speedups and energy savings compared to conventional computers, highlighting a promising route towards faster and more energy-efficient optimisation.
The collaboration aims to bridge the gap between academic research and real-world financial applications, leveraging quantum algorithms to process large volumes of scenarios more efficiently. By doing so, they hope to achieve faster valuation, improved precision, and more scalable approaches to managing derivative risks.
Researchers identified eight new DNA signatures in breast cancer and developed an open-access tool to visualize the data. The study's findings could help refine diagnostic tools and match patients with targeted therapies.
The study uses DNA barcodes to track and compare dozens of gold nanoparticle designs in living tumour models, identifying those effective at reaching mitochondria. Two formulations emerged as standout performers, achieving high tumour regression when combined with RNA therapy and photothermal treatment.
The team developed a predictive design strategy for creating nanographenes with multiple strongly coupled spins, offering enhanced resilience to magnetic perturbations. This breakthrough enables new avenues for molecular-scale quantum information technologies and next-generation spintronics.
Researchers at NUS create Lytic Selection and Evolution (LySE) platform, harnessing modified bacteriophage to rapidly create and test genetic changes. After five cycles, plastic degradation improved by over 50%, demonstrating a faster and more controllable method for training bacteria to consume plastics.
Researchers aim to develop novel quantum algorithms for molecular simulation, targeting computational bottlenecks in drug discovery. The collaboration combines expertise in quantum chemistry and sampling techniques with quantum computing capabilities.
Researchers from NUS engineered bacteria to restore metabolic balance across the gut, liver and brain, reducing brain toxins and preventing neurological symptoms. The approach preserves the natural diversity of the gut microbiome and has shown promising results in long-term safety studies.
Researchers at NUS have developed a paired protein language model (PPLM) to predict protein interactions, improving accuracy by up to 17% over leading methods. The model has strong performance across multiple tasks and can capture biologically meaningful relationships between proteins.
A new study by NUS confirms that word-picture guessing exercises with immediate feedback significantly improve adults' ability to recall new vocabulary in a second language. The research shows that attempting an answer first, even if not fully learned yet, strengthens memory and supports lasting learning.
Scientists at NUS create a DNA-based approach to directly measure the activation of Piezo1, a key protein that allows cells to detect physical forces. They find that Piezo1 can be activated by a force of about 15 piconewtons, providing new insights into cellular mechanics.
A new metahydrogel platform integrated with AI-driven signal processing suppresses motion noise, delivering clinical-grade accuracy in tracking fatigue levels with 92% accuracy. The system also enables broader neurophysiological and mental health monitoring with diverse biosignal types.
Researchers from NUS developed a boron-catalysed method to transform oxetanes into larger, medicinally relevant 1,3-oxazinanes with selective insertion of two building blocks, carbon and nitrogen units. This approach harnesses frustrated Lewis pair activation to upgrade cheap starting materials into bioactive compounds.
A research team from NUS has shown that compounds extracted from red dragon fruit peel can be incorporated into bread to increase antioxidant activity and slow starch digestion, offering a potential pathway to healthier staple foods and reduced food waste. The study found that optimal fortification levels of 0.75 per cent improve dough...
A study by National University of Singapore researchers found that NuSAP, a microtubule-associated protein, stabilises centriole architecture and recruits proteins necessary for proper centrosome engagement. This mechanism is critical to maintaining chromosome integrity and preventing developmental disorders.
Researchers have identified tyrosine phosphatase 1B (PTP1B) as a key molecular target in immunogenic cell death (ICD), a type of regulated cell death that activates the immune system against cancer cells. Two platinum-containing compounds, Pt-NHC and PlatinER, trigger ICD by blocking PTP1B's enzymatic activity.
The Centre for Computational Social Science and Humanities (CSSH) at NUS combines computational methods with social science and humanities to better understand complex social phenomena and develop solutions. CSSH aims to generate research that improves lives, strengthens institutions, and shapes more inclusive societies.
NUS food scientists develop a healthier, tastier kombu by co-fermenting enzyme-treated kombu with lactic acid bacteria and aroma-producing yeast. The resulting probiotic blend promotes nutrient bioaccessibility and introduces fruity aromas.
A new 'capping-and-coupling' strategy transforms native sugars into compounds known as C-heteroaryl glycosides in one step through photocatalytic carbon-carbon bond formation. This breakthrough enables simple and efficient coupling of diverse nitrogen-containing aromatics, offering a powerful avenue for late-stage glycosylations.
Scientists at NUS create electrochemical reaction manifold to access functionalized quinolines and N-alkylated saturated N heterocycles, both key scaffolds in pharmaceutical science. This breakthrough overcomes limitations of existing methods using strong oxidizing agents.
The new vapour-deposition method delivers unprecedented durability in perovskite–silicon tandem solar cells, achieving over 30% power-conversion efficiency and operating stability exceeding 2,000 hours. This breakthrough paves the way for real-world deployment of tandem solar modules.
Researchers at NUS develop dissolving microneedle patches to deliver beneficial microbes into plant tissue, accelerating early gains and using over 15% less biofertiliser. The approach points to precise fertiliser delivery, reduced waste and lower environmental impact.
Researchers from National University of Singapore develop two techniques to boost carob pulp's flavor, making it more appealing and sustainable than cocoa. The innovations aim to reduce the chocolate industry's dependence on cocoa and address climate change challenges.
Researchers at NUS developed a new heat-resistant material to strengthen the weakest link in perovskite-silicon tandem solar cells. The cross-linked molecular layer improved durability and efficiency over 1,200 hours of continuous operation.
Scientists at NUS and partner universities demonstrated highly efficient electroluminescence from lanthanide nanocrystals, marking an unprecedented level of control over exciton dynamics. The breakthrough enables devices to shift their color output across the visible to near-infrared spectrum with great efficiency.
Researchers at NUS have developed ultra-thin memtransistor arrays from 2D TMDC materials with controllable Schottky barriers, achieving high performance for image recognition tasks. The arrays demonstrate low device-to-device variation and high uniformity.
Researchers at NUS have discovered that certain DNA phosphates can act as catalysts for producing mirror-image versions of medicinal compounds. This new method uses 'ion-pairing' to guide chemical reactions, simplifying the process and making it more sustainable.
Scientists at NUS discovered a simple DNA switch that enables tropical butterflies to change the size of their wing eyespots in response to seasonal temperatures. This genetic element, called Antennapedia, is controlled by a previously unknown promoter that triggers its activation.
Researchers from NUS pioneered a photocatalytic atom-swapping transformation that converts oxetanes into four-membered saturated cyclic molecules. This breakthrough simplifies the synthesis of pharmaceuticals and complex drug analogues, reducing steps from 8 to 4.
A new study estimates that ongoing childhood lead exposure costs the world over $3.4 trillion annually, with disproportionate impacts on low- and middle-income countries. The researchers propose a four-pronged strategy to curb a resurgence in global inequalities and set back progress in children's health.
Scientists have discovered a surprising strategy plants use to thrive in sulphur-deficient conditions by releasing glutathione, which enhances plant growth but reduces bacterial growth. This 'trans-kingdom fitness trade-off' has implications for designing better microbial solutions for resilient crops.
Researchers at NUS have successfully applied cryo-EM to study two protein machines that transport lipids in bacterial cells, maintaining the outer membrane barrier. The OmpC-MlaA-MlaC complex deforms local membranes and loosens misplaced lipids, while the TolQ-R2A complex acts as a molecular motor to transmit force for lipid balance.
Scientists have observed a doping-tunable charge density wave (CDW) in single-layer semiconductor Chromium(III) selenide. The CDW phenomenon is extended to semiconductors, allowing for reversible tuning via surface charge transfer doping. This discovery provides insights into emergent orders in quantum materials and potential device ap...
Professor Lim Chwee Teck, Director of NUS iHealthtech, has been elected an International Fellow of the Royal Academy of Engineering for his pioneering research in biomedical engineering and wearable technologies. His work on disease diagnosis and therapy has translated into impactful healthcare solutions through start-ups.
Pharmaceutical scientists at NUS developed DOMEK method to characterise enzyme-substrate interactions, enabling analysis of thousands of potential substrates. The technique combines mRNA display and next-generation sequencing to calculate specificity constant for each substrate.
Researchers have devised a method to safely and temporarily 'switch off' and then 'turn on' ribonucleic acid (RNA) inside cells using disulfide-containing chemical groups. This strategy could potentially open new avenues in more precise RNA-based therapeutics and gene editing.
An international team of researchers has derived a quantum Bayes' rule from a fundamental principle, providing a breakthrough in mathematical physics. The discovery has potential applications in quantum computing for tasks such as error correction and machine learning.
Engineered peptides form nanonets that trap and kill bacteria, while leaving healthy cells untouched. The technology could inspire next-generation biomaterials for treating bacterial infections.
A NUS-led study analyzed coral samples from the Maldives, extending the sea-level record by 60 years and revealing an acceleration of rising sea levels since 1959. The findings show that the Indian Ocean has been highly responsive to climatic changes, with significant sea level rise of 30cm since the mid-20th century.
Researchers developed a groundbreaking carbon membrane that can enable high-precision proton beams for cancer treatment. The new material outperforms best-in-class materials like graphene and commercial carbon films.
Researchers from NUS have tracked changes in gene expression and splicing patterns in skeletal muscle after a 16-week lifestyle intervention program involving supervised exercise and dietary changes. The study found that participants lost weight and improved insulin sensitivity, with specific genes showing evidence of G x L interaction.
Researchers from NUS develop non-alternant carbon nanobelts featuring five-membered cyclopentadienyl units, allowing for improved electron flow and new electronic properties. The novel structures emit bright red light and exhibit small energy gaps, making them suitable for organic light-emitting diodes and solar cells.
Researchers have found that a lower dose of abiraterone acetate, 500 mg daily, is as effective in treating prostate cancer as the standard regimen, but with fewer side effects. The study involved nine men with metastatic prostate cancer and showed comparable cancer suppression through reduced PSA levels and hormone suppression.