Researchers have discovered that marigold flower proteins have excellent emulsifying, hydrating, and antioxidant effects, making them suitable for nutrient-enriched food formulations. The study found that marigold proteins stayed stable up to 221 degrees Fahrenheit, outperforming other plant proteins in terms of structure retention.
A new Edith Cowan University study found that activewear is worn for activities beyond exercise, such as shopping and studying, and can lead to self-consciousness and body comparison. The research suggests a complex debate surrounding the role of activewear in promoting physical and mental wellbeing.
A new study combines dynamic full-field optical coherence tomography with deep learning to generate real-time virtual pathology images of fresh lymph nodes during surgery. The approach achieved high accuracy and sensitivity, reducing tissue consumption and manual workload.
A new study reveals how maternal antibodies program the mouth to resist aggressive bacteria and prevent bone loss associated with adult gum disease. Maternal IgG also regulates the timing of barrier sealing in the oral epithelium.
The study reveals two distinct types of unusual low-energy quasiparticle states in CsV3Sb5, including a zero-bias conductance peak within the superconducting gap and Kondo resonance peaks that break mirror symmetries of the kagome lattice.
A new study reveals that ESBL-producing E. coli can persist on farmland and transfer to irrigation water, contaminating lettuce with measurable health implications. Household washing and extended manure management intervals can substantially reduce human exposure and associated health risks.
A new review calls for prevention strategies focused on specific human-animal interfaces, incorporating behavior-centered risk communication. China's experience with major outbreaks demonstrates the country's capacity for rapid communication and community engagement.
Researchers identified ten previously unknown symptoms strongly associated with eclampsia, including twitching and impaired speech. These symptoms were rare among women without seizures but frequently occurred before an episode, increasing the risk of seizures.
A new study found that young men who viewed idealized fitness or supplement videos on TikTok reported lower fitness satisfaction and stronger intentions to use creatine, a popular muscle-building supplement. The researchers highlight the need for targeted media literacy education and responsible social media practices.
A research team at SKKU has developed specialized 'One-body' materials for dry processes, maximizing battery performance and productivity. The breakthrough technology eliminates toxic liquid solvents, reducing costs and environmental impact.
The Center for Cellular Language Intelligence will decipher the complex communications that govern tumor ecosystems, revealing principles of cellular organization and biological programs influencing cancer initiation and response. Led by Linghua Wang, the center aims to accelerate discovery and deliver new therapeutic targets, predicti...
Researchers at UCSF discovered that single-celled organism Stentor learns through modifying existing proteins with calcium signaling, which is similar to the mechanism used by animal neurons. This finding suggests that learning may be a fundamental feature of life and could have evolved before the emergence of brains.
Researchers at the Smithsonian National Museum of Natural History analyzed 18 scorpion species and found striking patterns in metal concentration and distribution among their pincers and stingers. The study reveals that zinc plays a role beyond hardness, possibly enhancing durability, and provides insight into how organisms adapt to pr...
Cancer cases are on the rise among younger adults in England, with a significant increase in bowel and ovarian cancer rates. The study found that excess weight is a key contributor, but it's unlikely to fully explain this trend, as trends in risk factors such as smoking and diet have been stable or improving over the past decade.
An AI model called REDMOD can pick up the very early subtle tissue changes of pancreatic ductal adenocarcinoma, which conventional imaging and the human eye find difficult to detect. The model detected 'invisible' signature of pre-clinical pancreatic cancer an average of 475 days before clinical diagnosis.
A study by King's College London found that babies exposed to high levels of air pollution in the womb show slower signs of development at 18 months compared to those exposed to lower levels. This is particularly true for premature babies, who experience poorer motor and language skills.
A UCLA-led international collaboration has unveiled a new technology that enables scientists to directly compare how different molecules compete for the same binding site on a protein, all in a single experiment. The results show promising interactions between two cancer drugs and reveal previously unknown interactions.
The US Department of Energy has selected four companies to participate in its Nuclear Energy Launch Pad initiative, which aims to support the development and deployment of advanced nuclear technologies. The selected companies will receive technical, regulatory, and deployment support from the National Reactor Innovation Center.
Researchers at UTHealth Houston have been awarded a three-year, $7.8 million grant to better understand how Parkinson’s disease occurs in the brain. The project aims to identify proteins and cellular pathways involved in brain damage, with the goal of developing novel strategies for intervention.
Researchers found striking, decades-long cycles in US suicide rates, influenced by broad social forces. Suicide risk has been rising steadily for over half a century among young people, affecting each new generation earlier in life.
Researchers found that distinct patterns on lung scans can signal disease severity and predict breathing problems. The study's findings may help doctors tailor treatment approaches for patients with sarcoidosis.
Researchers at UIC developed an anti-cancer therapy using a bacterial protein called aurB, which prevents energy production in tumor cells' mitochondria. The treatment was tested in combination with radiation and showed highly effective results in animal models of prostate cancer, effectively shutting down tumor growth.
Researchers found that fish lineages adapted to scrape algae and shellfish from hard surfaces evolved in more diverse ways than those living in open water. Coral reef fish are thought to have benefited from this adaptation, driving the acceleration of diversification.
A four-decade long study found that even 'stable' carbon in forest soils can break down as temperatures rise, releasing more CO2. Microbial communities play a critical role in soil ecosystems and their changes can speed the loss of carbon from soils.
New study finds anaerobic digestion of hemp hurd-based bioplastic systems delivers the best environmental outcome, generating up to 6.1 kg less CO2 emissions per 1 kg mulch film treated. The production process significantly affects the final carbon footprint of biocomposites.
The BBVA Foundation Frontiers of Knowledge Award recognizes the Institute for Social Research (ISR) at the University of Michigan and NORC at the University of Chicago for their work in developing reliable data series on social sciences. The award acknowledges their contributions to objective measurement of public opinion, survey metho...
Research in Amazonas reveals that small amounts of Amazonian dark earth can increase the height and diameter of two tree species by up to 55% and 88%, respectively. The study attributes this growth to the reorganization of beneficial microorganisms around plant roots.
Engineers developed an adhesive gel that can deliver substances into plants' tissues, clearing bacterial infections within 48 hours. The gel sticks to various surfaces, including hairy leaves and stems, and can be removed without damage.
Chronic liver disease in the US costs $41.57 billion, with prescription medication expenditures accounting for nearly half of all-cause healthcare expenditures. Poor adherence to antiviral medications is a key factor in preventing disease progression and treatment, with high out-of-pocket costs increasing non-adherence risk.
A $456,000 grant from Critical Path Institute will support the development of a brain-penetrant therapy for glycosphingolipid storage disorders. The therapy aims to address neurological symptoms in patients with current limited treatment options.
Biofortifying staple crops like rice, wheat, and maize can reduce the risk of non-communicable diseases and improve nutrition. Researchers have developed high-protein rice with elevated essential amino acids, which can also help manage blood sugar levels.
Simulations by a team of scientists show that unrestricted information sharing can lead to less accurate collective beliefs, particularly in socially homogenous settings. This phenomenon is driven by homophily and the amplification of erroneous ideas within groups.
Researchers have developed a perovskite diode that can convert sunlight to electricity and emit light with high efficiency, resolving the challenge of doing both. The device achieves a world-record 26.7% efficiency in converting sunlight to electricity and 31% efficiency in emitting light.
A first-in-human clinical trial found that setidegrasib, a targeted therapy drug, demonstrated early antitumor activity in advanced lung and pancreatic cancers. The therapy shrank tumors and delayed disease progression in some patients, providing a potential new treatment approach for KRAS G12D-driven cancers.
A new study reveals that releasing goldfish into the wild can trigger a regime shift in freshwater ecosystems, leading to degradation and harm to native wildlife. The research calls for stronger public education campaigns and prevention strategies to control invasive goldfish populations.
Researchers at Indiana University School of Medicine developed a new method to analyze brain energy network patterns, revealing insights into Alzheimer's disease progression. The study found that brain networks reorganize as the disease progresses, with memory and language functions showing increased metabolic demand in early stages.
Motif Neurotech has received FDA approval to begin the first clinical trial of its therapeutic BCI device, DOT, for treatment-resistant depression. The study will test the device's effectiveness in delivering electrical stimulation to brain circuits linked to depression.
Researchers at the UC Davis MIND Institute found that polychlorinated biphenyls (PCBs) alter genes more in females than males, with a key gene called XIST playing a protective role. Folic acid also shows promise in mitigating harmful effects of PCB exposure, particularly in women.
A new review found that lifestyle behaviors like physical activity and diet can positively modulate the gut microbiome of cancer patients, but these effects are often influenced by non-modifiable variables. The study also highlighted the role of intrinsic patient characteristics in shaping microbial composition.
Researchers at NYU Abu Dhabi developed soft, flexible sensors that measure force in real-time during minimally invasive surgeries. The sensors, made from silicone and liquid metal, can detect a wide range of forces and are easy to integrate with existing tools.
A study found that prey scarcity is a key factor in jaguar presence in protected areas of the Atlantic Forest, with reduced abundance and biomass due to human hunting. The researchers warn that this situation could lead to the biome losing its top predator population.
A large study found that individuals with difficulty recognizing and expressing emotions experience greater disruption to daily life from pain over time due to increased psychological distress. The study also suggests that addressing emotional processing difficulties may be key to improving long-term outcomes for people with chronic pain.
A new Cornell University study reveals that social media boycotts have less impact on music streams than platform sanctions. In several high-profile controversies, scandal-related attention coincided with short-term increases in streams. However, when platforms reduced visibility of the artists' music, clearest declines appeared.
Researchers have created lab-grown human skin organoids that can form complex microvascular networks similar to those in native human skin. These self-organizing structures function similarly to native skin, responding to inflammatory stimuli and re-growing after injury.
Researchers at the University of Illinois have developed a machine learning model that can predict chick embryo mortality using hyperspectral imagery, reaching accuracy of up to 97%. They also successfully identified male embryos with high accuracy, potentially reducing the culling of male chicks in hatcheries.
Researchers at Texas A&M University created HIPPO, a browser extension that generates unique passwords for each website without storing them. Participants preferred HIPPO over traditional password tools for ease and security, reporting higher satisfaction rates.
A preclinical study found that mice stopped and restarted GLP-1s gained less weight over time, with a significant decrease in muscle mass. The researchers suggest that clinicians help patients preserve muscle mass while on these medications through exercise or nutrition.
A team of scientists at the University of California, Davis, has discovered an inherited form of blindness directly comparable to autosomal dominant optic atrophy (ADOA) in rhesus macaques. The study could lead to a better understanding of ADOA and potentially new treatments.
Researchers discovered a molecular complex linking abscisic acid to sucrose metabolism in grape berries, accelerating sugar accumulation and berry ripening. The VvMYB44-VvERF045 pathway activates the key gene VvSPS4, enabling a clearer understanding of how hormone signaling translates into biochemical changes affecting fruit quality.
A Concordia-led study analyzed 53 green alleys and 23 conventional alleys in Montreal and Trois-Rivières, finding that results depend on alley design and purpose. The study suggests a middle ground between community-led projects and standardized approaches to achieve both biodiversity and social cohesion.
Visitors to a California region with numerous substance use disorder treatment centers experience higher levels of overdose, particularly out-of-state individuals. The study suggests that the industry's lack of oversight and predatory practices contribute to this hotspot.
CPSS cause hyperammonemia, hepatopulmonary syndrome, portopulmonary hypertension, and liver nodules/tumors. Detection relies on Doppler ultrasound, CT angiography, and MRI. Treatment depends on shunt type and severity, with endovascular or surgical options available.
A study identifies subtype-specific programs in pediatric ependymoma, linking metabolic patterns to clinical aggressiveness. The research reveals distinct metabolic profiles for each molecular subtype, providing a resource for understanding the biology of pediatric ependymoma and potential therapeutic vulnerabilities.
Researchers developed a fleet of cooperative robots that, like ants, can spontaneously organize to build and dismantle structures without central control. They identified key parameters needed for excavation and building performance using simple local rules.
Micro-gesture recognition is emerging as a key area of research in affective computing, focused on analyzing subtle, involuntary body movements that may reflect hidden emotional states. The field has expanded from RGB video to skeleton, audio, text, and privacy-preserving multimodal settings.
Researchers recorded single-unit activity in bats' inferior colliculus while they were freely vocalizing. The study found that 95% of neurons responded differently to self-generated vocalizations than to playback of the same calls.
A UK-led trial found that a procedure to reopen blocked heart arteries can reduce chest pain and improve quality of life. Patients who received the treatment had more angina-free days and better quality-of-life scores than those in the placebo group.
A new study published in BMC Medicine found that the experimental drug ZED1227 inhibits the activity of the transglutaminase 2 enzyme, reducing immune responses triggered by gluten. The results suggest that the drug has effects beyond the gut, dampening whole-body immunometabolic responses.
Scientists created hybrid macrophages that can simultaneously promote blood vessel and bone growth, potentially improving outcomes for patients with bone fractures. The discovery could lead to new cell-derived therapies that speed up recovery and improve healing.
The Harvard-led team demonstrates a micron-scale photonic device that generates two orders of magnitude more UV light on a chip than previous approaches. By converting red light to UV light through frequency upconversion, the researchers create high-power, low-loss, compact UV sources.
A recent study by Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau found that light pollution significantly alters the composition of predatory spiders' diets, leading to reduced hatching of insects. The invasive signal crayfish also contributes to altered feeding behavior under nighttime lighting.
A specific region of Dicer must be activated to achieve proper cell division and reproduction, a discovery that sheds light on the regulation of this enzyme's critical role in both cancer biology and fertility. This finding opens new avenues for studying how small epigenetic changes contribute to disease.
A new analysis of nearly 400 young participants found that those starting a healthy lifestyle program in spring showed weaker improvement than those beginning in summer, autumn, or winter. The study suggests that school calendars, daily routines, and long holiday breaks can impact treatment success.
A new study from Mayo Clinic suggests that Alzheimer's disease may start as early as the late 50s, with subtle biological changes accelerating over time. Researchers analyzed data from 2,082 participants and found that biomarkers of tau pathology and neurodegeneration show more pronounced increases around ages 68 to 72.
A review article analyzes InP quantum dot synthesis, core/shell optimization, ligands, and charge management for high-performance QLEDs. The study reveals the intrinsic relationship between microscopic material properties and macroscopic device performance.
Dampening, a phenomenon where positive emotions are diminished, can undermine well-being over time. Research found that future-focused thoughts, such as 'positive feelings won't last,' are strong predictors of depressive symptoms.
A large cohort study found that ABC risk factors carry greater cardiovascular significance at younger ages but become less relevant with age. The study supports an age-adapted approach to diabetes risk-factor management and highlights the importance of individualized treatment decisions in older adults.
Researchers from Lund University successfully harnessed the regenerative capacity of Scandinavian flatworms to accelerate wound healing in human skin models. The study found that signalling molecules from flatworm exosomes increased skin thickness and improved wound healing rates, including accelerated blood vessel regeneration.
Researchers discover zinc levels control endoplasmic reticulum redox enzymes necessary for proper protein folding. Zinc surge disrupts oxidative folding, leading to protein misfolding and cellular defects.
A study by the University of Trento reveals that ultra-stable glasses exhibit almost identical basic vibrations to normal glass, contradicting previous computer simulations. This finding suggests that vibrational modes are less sensitive to disorder than thought.
A Mayo Clinic study found that bariatric surgery reduces long-term cardiovascular risk more effectively than weight-loss medications. The study analyzed outcomes for 812 adults with obesity and found that greater weight loss led to larger reductions in lifetime cardiovascular risk.
Researchers at the University of East Anglia have discovered that light can be programmed using its natural geometry, allowing for the creation of structured light with unique properties. This breakthrough has far-reaching implications for fields such as medicine, data transmission, and quantum technologies.
The Patient-Centered Outcomes Research Institute (PCORI) has awarded funding for new patient-centered comparative clinical effectiveness research projects. These studies will examine different approaches to care across various health concerns, aiming to generate evidence for patients to make informed choices.
New research from the University of Texas at Austin finds that regulators with ties to Big Four accounting firms are less likely to detect financial statement errors and ask for amendments. A cooling-off period might increase confidence in regulatory oversight, but its implementation could be challenging due to staff limitations.
Dr. Indra Narang, a pediatric respirologist and sleep medicine specialist, has received the 2026 Inclusive Leadership Award for her work to broaden access and representation in sleep medicine. Her research focuses on improving diagnosis and treatment of childhood obstructive sleep apnea with an emphasis on equity-driven innovation.
A study reviews benchmark datasets, evaluation metrics, fusion strategies, and model development in multimodal deception detection. The field is moving toward more practical, scalable, and context-aware systems that combine verbal and nonverbal evidence.
The Biophysical Society condemns the mass dismissal of the National Science Board, which plays a crucial role in shaping US science policy. The board's absence jeopardizes fundamental research and development, hindering the country's global leadership in science and technology.
The study reveals that rising temperatures are accelerating permafrost thaw and glacier retreat on the Tibetan Plateau, forming thermokarst lakes that release ancient, long-frozen carbon as potent greenhouse gases. The research highlights the urgent need for typology-based management strategies to mitigate these emissions.
The study reveals that the interplay between EZH2 and Ca2+ signaling pathways can be harnessed to improve CAR T-cell efficacy in tumor control while preventing graft-versus-host disease. This balance allows for effective cancer treatment while minimizing transplant rejection.
A new genetic mechanism has been discovered in eggplants, allowing for precision breeding and maintaining attractive pigmentation under variable growing conditions. The study identified a previously unknown promoter switch in the SmMYB113 gene, which enables anthocyanin production even without light.
A new study suggests that seasonal influenza vaccines may significantly reduce the risk of death from H5N1 infection. The study found that vaccines including a specific component, neuraminidase N1, reduced H5N1-related mortality by approximately 73 percent in vaccinated animals.
Researchers at Mayo Clinic have developed a blood-based method to detect germ cell tumors, the most common type of testicular cancer, including cases that do not show up on standard blood tests. The new test, GCT-iSIGN, identified 93% of individuals with germ cell tumors and correctly ruled out cancer in 99% of those without.
A new review proposes a prevention-focused framework for understanding Parkinson's disease risk, highlighting the role of early-life vulnerability, environmental exposures, and resilience factors. The study suggests that susceptibility to PD may begin earlier in life through interactions between biology and environment.
Researchers found higher rates of suicidal ideation among individuals who died by firearm suicide after 2020, but lower engagement in mental health treatment. Demographic shifts also occurred, with more young, male, and minority decedents, highlighting gaps in suicide prevention strategies.
Researchers discovered that ultrasoft elastic materials generate a V-shaped wake similar to boat wakes, blurring the distinction between wave behavior on solids and fluids. This finding could lead to new approaches for soft-tissue diagnostics and understanding the properties of natural and engineered soft materials.
Researchers at Rice Biotech Launch Pad are developing an encapsulation platform to protect transplanted pancreatic islet cells from immune attack. The approach aims to reduce scarring and inflammation, making it possible for people with Type 1 diabetes to manage their condition without long-term immunosuppression.
Artificial platelets have been developed that remain stable and effective after a year at room temperature and two months at high temperatures. This technology could enable direct injection of synthetic platelets into bone marrow to treat life-threatening bleeding in remote areas or disaster zones.
A new chemical model developed by researchers at GEOMAR accurately predicts iron chemistry in the South Pacific Ocean, taking into account diverse organic matter properties. The findings improve understanding of the marine iron cycle and its implications for climate change.
The study reveals that the structural transition of SnTe originates from atomic-level mismatches between S/Se and Sn. SnTe retains a cubic structure due to its similar physicochemical properties with Sn, enabling it to exhibit remarkable advantages in conductivity, tap density, and lithium-ion diffusivity.
Harvard engineers develop new method to preserve long molecular chains in natural rubber, resulting in composite materials that are both stiff and tough. The innovation has the potential to cut waste, reduce tire dust pollution, and open new avenues for high-performance elastomers.
Digital Science has upgraded its world-leading Dimensions Research Security platform with a full workflow solution addressing growing volumes, fragmented tools, and rising compliance pressure. The new solution enables proactive research security work with reduced manual effort, making it easier to generate, customize, and access reports.
A new study found that Catholic men are the most likely group to engage in sports gambling in the US, contradicting the long-held assumption that religion discourages such behavior. Researchers also discovered that people who infrequently attend religious services are more likely to gamble on sports than those who attend regularly.
Researchers agree on core elements of ACLF development, including chronic liver disease triggers, acute insult, and extrahepatic organ failure. A new three-stage mouse model supports testing of potential therapies, highlighting impaired liver regeneration as a key driver of disease progression.
A Rutgers study examines the challenges and opportunities of community violence intervention programs in semi-rural communities. The research highlights the importance of flexibility, strong partnerships, and local relationships to effectively respond to violence in broader geographic areas.
Researchers from NUS engineered bacteria to restore metabolic balance across the gut, liver and brain, reducing brain toxins and preventing neurological symptoms. The approach preserves the natural diversity of the gut microbiome and has shown promising results in long-term safety studies.
A study published in PLOS Medicine found that age at initial diagnosis, sex, and type of first cancer significantly affect the risk of developing a subsequent primary cancer. Older age and male sex were associated with a higher risk, while survivors of lung, bladder, and skin melanoma were also at increased risk.
Scientists create a novel nano-delivery system that boosts NAD+ synthesis and reduces consumption, rapidly restoring energy metabolism in damaged kidneys. The approach halts disease progression and prevents chronic kidney disease, offering a promising drug development platform for AKI and other energy metabolism disorders.
Rivers are warming, losing oxygen, and accumulating greenhouse gases, with estimated annual emissions of 1.5 billion metric tons of CO2 equivalent. Climate change and land use drive these processes, but protecting rivers can help mitigate global warming.
A recent survey found that 31% of 16-year-olds and 39% of 18-year-olds had sent sexually suggestive photos or videos. Most teens receive these messages from strangers, while those in relationships often send them to their partners.
Researchers introduce generalized perfect spatiotemporal optical vortices with topological-charge-independent sizes and fully controllable geometric shapes. The new method achieves higher modulation efficiency and improved energy utilization, exceeding 90%.
A nationwide ecological study found a statistical correlation between fewer psychiatric beds and higher suicide rates in Sweden. The study suggests that investing in outpatient care may not be enough to prevent suicides, highlighting the need for further research into healthcare resource allocation.
A team of researchers designed a bismuth-coordinated melanin material to shield against radiation and alleviate acute radiation syndrome (ARS), with promising results in mouse experiments. The material showed stronger shielding and antioxidant effects, improving survival rates from 20% to 60%.
Researchers found that plants can acquire essential nutrients like phosphorus and iron from atmospheric dust settling on their leaves. This discovery suggests an important new pathway for plant nutrition and ecosystem functioning, particularly in nutrient-limited ecosystems.
Researchers have discovered a pattern in ultra-low temperature measurements of quantum Hall effect states, which can be explained by the composite fermion (CF) theory. The findings propose a connection between CFs and the observed states, providing a new understanding of fractional quantum Hall states.
Researchers at Beihang University developed a hierarchical modular film system that couples biomimetic temperature-humidity sensing with dual-mode heating and ultrahigh EMI shielding. The system delivers exceptional metrics, achieving stable signal transmission and collaborative heating under diverse conditions.
Researchers at Linköping University developed a digital twin model to predict alcohol consumption and drinking patterns. The tool uses data from exhaled breath, blood, and urine samples to generate individualised results, providing a more accurate picture of when a person last drank.
A comprehensive survey of 4,000 adults in northern China reveals alarming gaps in public knowledge about preventing tick-borne diseases. Rural residents and high-risk groups paradoxically show the lowest protective awareness, highlighting a critical need for targeted health education interventions.
Researchers from China have successfully demonstrated CRISPR/Cas genome editing in nonregenerative cotton via sexual hybridization, opening a novel technical avenue for genetic improvement. The approach eliminates toxicity in cottonseed protein, enabling valuable resource utilization and advanced biotechnologies.
Researchers found that hydrogen in LaH3 can tunnel through energy barriers rather than surmounting them, with quantum tunneling becoming dominant at approximately 71 K and increasing to 308 K for single-ion migration. This study clarifies why classical models fail to capture key aspects of the underlying physics.
Researchers developed curvature-optimized multilevel SERS substrates using femtosecond laser shaping, exhibiting enhanced Raman signal intensity and uniformity. The substrate features triple cross-scale structures with flexible shape parameters, promoting dimensionally ordered hot spots for improved detection sensitivity.
Researchers found that exercising to self-selected music boosts endurance by nearly 20%, allowing individuals to tolerate sustained effort for longer. Participants cycled for an average of 35.6 minutes with music versus 29.8 minutes in silence, with no change in heart rate or lactate levels at the finish.
Researchers at Kyushu University developed a new mathematical model that simulates oxygen transport by red blood cells through tiny blood vessels and their delivery to surrounding tissues. The findings show that RBCs can naturally adjust the amount of oxygen released based on local requirements.
A new paradigm shift in cancer research defines valid primary study endpoints for oligometastatic disease, focusing on treatment-free time and minimal side effects. The consensus paper establishes two new metrics: STFS (Start or Switch of Systemic Therapy–Free Survival) and pPFS (polymetastatic Progression–Free Survival), which capture...
Researchers at the University of Cordoba developed MAPLID, a tool that maps city structures and pace based on how residents use their cell phones. The multi-label classification provides information on population density changes and traffic patterns.
A new study published in The Innovation Medicine found that long-term exposure to air pollution significantly increases the risk of cardiovascular disease (CVD) in individuals with cardiovascular-kidney-metabolic (CKM) syndrome. Exposure to fine particulate matter and cooking fuel was linked to a higher risk of CVD.
A recent study has developed an analytical model of downburst wind fields, which reproduces key observable features while adhering to fundamental mechanical principles. The model proposes a framework for assessing train overturning due to downbursts, with high train speeds identified as the most significant contributor to increased risk.
Researchers discovered Trichobilharzia franki parasites in Lake Alqueva, marking the first confirmed record of avian schistosomes in Portugal. The finding highlights potential cercarial dermatitis risk in Europe's largest artificial reservoir.
A new study examines the One Health approach for tick-borne disease management in the Middle East and North Africa region. The research highlights critical gaps in current control strategies, including limited understanding of acaricide resistance patterns and incomplete epidemiological surveillance systems.
A new tool has been developed to fund wetland conservation and restoration projects through verifiable Coastal Resilience Assets. This approach uses engineering methods to quantify the impacts of conservation and restoration projects on property value protected from flooding, providing a clear and tangible use case for asset buyers.
Researchers at LMU Munich develop a surface treatment method to optimize the molecular contact in perovskite solar cells, resulting in improved efficiency, reproducibility, and stability. The approach provides a scalable solution for industry-compatible fabrication workflows.
Scientists have uncovered an unexpected way cancer cells generate cancer-driving proteins by cutting RNA into shorter fragments. This process, termed as RNA dicing, enables the production of a truncated form of the JAK1 protein that remains highly active and can promote tumor growth.
Researchers found that urban birds flee sooner when approached by women compared to men in a European study. The study involved over 2,700 observations across five countries and 37 bird species, revealing that birds can recognize the sex of approaching humans.
A study by University of Barcelona researchers has identified a key protein called Polμ that enables macrophages to survive at the site of inflammation. This discovery could have implications for understanding and treating autoinflammatory diseases and conditions such as septic shock.
The 2026 Semmelweis-Richter Journalism Award is now open for entries, with a focus on high-quality health journalism and its impact across Europe. Journalists can submit articles in two categories until June 9, 2026, with a total prize fund of €45,000.
Scientists developed a Tuneable Magnetic End Effector to control microrobots for targeted and minimally invasive healthcare. The technology enables precise delivery of therapies directly to diseased tissues, reducing damage and side effects.
Researchers developed a multi-physics machine learning framework that improves stress prediction accuracy by integrating electrical resistivity. The model achieved significant reductions in mean absolute error and improved coefficient of determination, making it a promising approach for real-time monitoring of compressive stress in UHPC.
Researchers at KAUST have developed a resilient renewable energy system capable of meeting electricity demand during extreme weather conditions in hot desert regions. The system combines concentrated solar power, photovoltaic panels, wind turbines with battery and thermal storage, reducing CO2 emissions by 330,000 tonnes annually.
The kinase field offers significant therapeutic opportunities, with many understudied kinases waiting to be explored. Recent advances in chemical probe development and resource availability have led to a shift towards more systematic exploration of previously neglected targets.
A new study by the University of East London found that newer blockchain systems significantly reduce energy consumption, from 100-150 TWh per year for Bitcoin to negligible amounts. This shift has already led to reductions in network energy use and enables wider adoption at scale.
Researchers identified thermotolerant Campylobacter spp. in South American camelids (SACs) with a prevalence of 3.2%, revealing species-specific differences in bacterial colonization. Elevated antimicrobial resistance was detected, posing public health concerns.
Researchers developed a new imaging method to visualize how food spreads through ant groups in real time, offering insights into collective health and potential early warning signs of disruption. The technique allows for precise measurement of food distribution patterns across various species.
Researchers have developed a series of carbonyl-rich carbon sphere catalysts with unique wrinkled surface architecture, significantly enhancing the catalyst's performance in hydrogen peroxide electrosynthesis. The optimized catalyst achieved high H2O2 selectivity and efficiency.
Researchers studied evolution of Scalesia genus, finding lobed leaves evolved through multiple genetic pathways. The study highlights the flexibility and creativity of evolution, with new species forming and populations showing large genetic differences.
Researchers found that small understory trees can initially buffer climate change more strongly, but their long-term carbon storage capacity could be restricted by phosphorus availability. The study suggests a critical trade-off between short-term growth and long-term sustainability.
This study investigates the effects of high-volume fly ash on early-age characteristics and hardening properties of concrete. The results show that fly ash can improve fresh concrete workability but delays setting time. However, moderate fly ash replacement achieves excellent long-term strength and stiffness.
Researchers introduce Radon transform-based flow measurement (R-Flow), a contrast-free ultrasound method that visualizes blood flow dynamics at the microvascular scale. The technique captures complete 2D flow patterns and demonstrates high accuracy in detecting pathological changes in diseases like cirrhosis.
A randomized clinical trial found that proactive outreach for care coordination did not lead to better outcomes compared to usual care post-hospitalization coordination. Many participants declined the offer. The study suggests that current strategies may need to be reassessed.
Researchers developed a coarse-to-fine saliency-driven maritime ship detection network to improve detection accuracy in complex scenes. The framework achieves high F1 scores and mean average precision, outperforming strong baseline detectors.
Researchers found that soil fungi are essential for native forest re-growth and ecosystem health on Palmyra Atoll. The symbiotic relationship between Pisonia trees and fungal partners is critical for the atoll's unique ecosystem.
A nationwide Swedish study of 27,789 individuals with confirmed celiac disease found no link between antibiotic use and increased risk of developing the autoimmune disorder. The study also revealed a higher proportion of prior antibiotics used among those with normal mucosa, suggesting other factors may contribute to its development.
Researchers developed a Fe-Mg dual-atom catalyst that regulates spin states to optimize the oxygen reduction reaction, achieving exceptional electrocatalytic metrics and surpassing platinum benchmarks. The optimized catalyst delivers outstanding stability and viability for real-world applications.
Researchers have created a detailed diagram of smell receptors in the nose, revealing a highly organized receptor map that mirrors the organization of smell maps in the brain. The discovery sheds light on how information moves from the nose to the brain and could lead to therapies for loss of smell.
University of Oregon researchers have created an electrochemical tool that can quantify and separate the factors influencing coffee taste. The innovation allows cafes to improve quality control with a simple measurement, while also helping scientists understand individual tastes at a molecular level.
Researchers developed a new method to identify cellular features supporting metastatic cancer growth, revealing an unexpected driver of immune suppression in bone metastasis. Estrogen receptor alpha-activated macrophages play a key role in immunosuppression and tumor progression.
Researchers develop solar-powered technology to convert plastic waste into valuable fuels, including hydrogen and syngas, reducing reliance on fossil fuels and addressing pollution challenges.
A recent study published in JAMA Network Open found that half of older patients with dementia remain on psychotropic drugs a year after starting them. The medications, including antipsychotics and benzodiazepines, are often prescribed in acute and post-acute settings such as emergency rooms and skilled nursing facilities. This raises c...
Researchers created a detailed diagram of smell receptors in the nose, revealing that they form horizontal stripes based on receptor type from top to bottom. The study provides foundational information for developing therapies for loss of smell and offers insights into how information moves from the nose to the brain.
A study by the University of Cambridge found that racism and socioeconomic stress can alter key physiological processes in the body during pregnancy, leading to higher rates of preeclampsia and preterm birth in black women. These changes are not due to genetic differences but rather persistent socio-environmental stressors.
Engineers at MIT and their collaborators create a new type of soft magnetic hydrogel that can be made into complex, magnetically activated three-dimensional structures. The new gel enables the creation of microscopic, magnetically responsive robots and materials with micron-scale precision.
Researchers designed a force-sensing miniature robot to handle delicate cell spheroids with precision. The mobile microgripper uses magnets for controlled movement and gentle gripping, allowing successful assembly of spheroids into patterns.
Researchers developed meta-earplugs with Helmholtz resonators to address low-frequency sound issues. The earplugs use precise tuning of reflected sound waves to relieve pressure and increase protection.
A new study reveals the developmental mechanism of bone marrow formation, identifying septoclasts as early organizers followed by LepR-expressing bone marrow stromal cells. These specialized cell populations work together to build the bone marrow environment through a hardwired process supported by RANKL.
Researchers found that exposure to aggressive diplomatic messaging reduces favorability towards China in Japan, South Korea, and Taiwan. In contrast, perceptions of the US are less affected, with limited persuasive power.
Independent academic clinical trials are essential for improving patient outcomes, reducing inequalities in care, and strengthening healthcare systems. The Lancet Oncology Commission aims to deliver actionable recommendations to ensure these trials continue to benefit patients and society worldwide.
A study by researchers at the University of Basel reveals that the immune system fights lifelong viral infections acquired at birth, with partial success. The body gradually produces antibodies to reduce virus amounts, supported by T helper cells, but the response remains limited.
A new AI model, PLGMamba, improves hyperspectral image super-resolution by combining local spectral similarity with global feature modeling. The approach achieves stronger reconstruction accuracy than several leading super-resolution methods and overcomes limitations of existing models.
A cross-sectional study found that older adults are disproportionately prescribed medications affecting cognition from acute or postacute care settings. This highlights the need to target prescriptions from these settings to reduce such prescribing.
A pinecone-inspired self-curling adhesive conduit was developed to provide adaptive wrapping for peripheral nerve repair, achieving faster curling speed and higher bending curvature than existing conduits. The material demonstrated good biocompatibility, promoting cell migration and creating a favorable repair microenvironment.
A novel circular RNA replicon was identified in a high-temperature hot spring ecosystem, showing profound divergence from previously known circular RNAs. The discovery reveals diverse self-replicating RNAs exist even in extreme environments, broadening the ecological scope of RNA-based replication systems.
Tomatoes have difficulty germinating under prolonged heat stress, but two mutant lines with the loss-of-function mutation in SlIAA9 showed little decline in germination and normal seedling development. The mutants exhibited elevated expression of antioxidant enzymes and heat shock proteins, leading to enhanced resilience to heat stress.
Researchers developed an ultrafast transient absorption microscope to analyze fluctuations and heterogeneities in light-harvesting antennae. The study revealed two kinetic components with nearly identical time constants and quantified photophysical properties associated with these components.
Researchers identified an ion channel that opens and closes in response to extracellular potassium ions in fruit flies, and found similar functionality in humans. This discovery reveals a novel sensor for extracellular K+ levels, potentially linking to diseases like epilepsy.
Dr Hendricks-Sturrup brings expertise in biomedical research, bioethics, and policy to lead the editorial board. Her experience will focus on disseminating high-quality research globally.
Researchers used LiDAR surveys to analyze medieval mountain castles' topography, distinguishing between human-made and natural landscapes. The study found that castle sites exhibit greater variability in slope compared to unmodified natural ridges, with high slope variability linked to landslide traces within the castle boundaries.
Researchers have developed a deep-learning framework to reconstruct a global, high-resolution nighttime light dataset from 1992 to 2024. The new product improves upon existing datasets by reducing saturation-related bias and better capturing temporal changes in urbanization, economic activity, and human development.
Researchers discovered that malaria parasite PI3K suppresses 'eat-me' signal to evade host immune system. By inhibiting PI3K, phosphatidylserine exposure increases, enhancing macrophage recognition and clearance of infected red blood cells.
Researchers found that Pseudomonas syringae triggers P-bodies to reduce protein synthesis, impairing plant defense mechanisms. This manipulation also involves reprogramming cellular stress responses and autophagy, adding layers of complexity to bacterial infection strategies.
A new 10-year project agreement advances US-EU collaboration on Wendelstein 7-X stellarator, a key experiment in fusion energy. The framework streamlines processes for joint research projects and provides a consistent legal structure for partnerships.
The new NCCN Guidelines for Patients: Prostate Cancer Screening provide a comprehensive guide to evidence-based recommendations for age-specific screening. The guidelines aim to balance the benefits of early detection with the risks of unnecessary procedures, emphasizing the importance of personalized care and monitoring.
A study on the phylogeography of Burmannia nepalensis, a rare mycoheterotrophic herb in subtropical China, found that historical climate fluctuations and geographic isolation shaped its evolutionary history. The research reveals limited gene flow due to mountain barriers and fragmented habitats.
A global research network, led by ASAP and MJFF, is expanding its efforts to map the biological blueprint of Parkinson's disease and develop a standardized toolkit of global research resources. This expansion aims to accelerate the development of personalized therapies by understanding the disease's inherent heterogeneity.
Researchers developed a machine learning model to identify insects based on radar reflection changes from wing flapping. The model achieved high accuracy in distinguishing between species, including bees and wasps, with an accuracy of 96% and 85%, respectively.
Researchers developed BikeButler to provide personalized bike routes for cyclists in Seattle. The app uses a visual language model to analyze street images and rate subjective attributes like greenery and pavement quality.
EGFR-TKIs have significantly improved OS and quality of life for EGFR-mutant NSCLC patients. However, ongoing research is needed to refine therapies for precise individualized treatment, addressing resistance mechanisms and optimal combination strategies.
Researchers found that integrating a mix of shade trees improves soil health and plant physiology, leading to stronger plant growth and consistent early fruit development. Proper management through spacing, pruning, and natural mulch can also make cacao farms more resilient to climate stress.
Researchers identified blocking ID1 and ID3 as a promising therapeutic strategy to halt and reverse lung scarring in idiopathic pulmonary fibrosis. The approach showed significant reduction in lung scarring and improvement in lung function across multiple experimental systems.
A recent CNIO study has identified a key mechanism in the development of liver fibrosis by targeting bile duct cells. The research reveals that these cells regulate liver health and form a barrier that prevents bile acid leakage and fibrosis, opening new avenues for personalized treatment.
A UCLA-led study reveals that airborne desert dust traps about twice as much heat as previously estimated, leading to improved climate and weather models. This increase in precision will help forecasters predict regional temperature shifts, rainfall patterns, and atmospheric motions.
Research highlights how everyday factors from early life through adulthood influence brain health and affect the risk of developing cognitive decline, dementia or stroke. Healthy lifestyle habits such as regular physical activity, healthy sleep habits, and balanced eating patterns can support brain development and healthy aging.
Orange County residents hold broadly positive but carefully qualified views on immigration, recognizing its benefits while drawing distinctions around enforcement. The UCI-OC Poll found that Orange County residents are pragmatic about immigration, supporting targeted enforcement against human trafficking and limiting immigration from u...
A new study suggests that an AI tool analyzing facial changes can serve as a prognostic biomarker for cancer prognosis. The researchers found that patients with higher biological aging rates had lower chances of survival, and the effect was strongest when photos were taken over longer intervals.
A decades-long study of oceanographic data shows that warm water has expanded and shifted towards the Antarctic continental shelf, posing a threat to ice shelves. The Southern Ocean's circulation has changed, allowing excess heat from global warming to reach Antarctica's vulnerable ice sheets.
A 30-country survey found that digital health literacy is highest in low- and middle-income countries, where social media plays a key role. The study also highlights variation in trust for credible sources, with medical providers being the most trusted, followed by verification through multiple sources.
The Mediterranean fin whale population is found to be genetically connected to North Atlantic populations, contrary to previous assumptions. This finding highlights the need for reevaluation of conservation strategies and increased connectivity between populations.
A new study by researchers at IMT School for Advanced Studies Lucca analyzed over 3,700 reports of dream and waking experiences to understand what determines the content of dreams. The findings show that both individual characteristics and shared life experiences play a key role in shaping dream content.
New research from the University of Waterloo shows that social media posts can speed up wildfire response but also trigger costly over-reaction. The study analyzed Twitter data on California wildfires and found that while emotional posts can amplify urgency, they also distort resource allocation.
Researchers have created an ultra-thin, lightweight shielding material that blocks 99.999% of electromagnetic waves and reduces neutrons by approximately 72%. The material is also stretchy like rubber, suitable for 3D printing and can withstand extreme temperatures.